- Yale Pediatric Endocrinology1 Long Wharf DriveNew Haven, CT 06511
- Yale Diabetes ClinicDana Clinic Building789 Howard Avenue, Ste 2nd FloorNew Haven, CT 06519
Ania Jastreboff, MD, PhD
Biography
Ania M. Jastreboff, MD, PhD, is an adult and pediatric endocrinologist with expertise in obesity medicine and weight management. She cares for patients who have prediabetes, insulin resistance, metabolic syndrome, and type 1 and type 2 diabetes.
Dr. Jastrebroff says she emphathizes with patients who struggle to lose weight or maintain weight loss. “Carrying excess weight and having obesity is not a lifestyle choice. Obesity is a chronic disease and should be treated with the same vigor and integrity as other chronic diseases,” she says. “We are in the infancy of our understanding of the mechanisms that underlie obesity. Many novel treatments are under development, including new anti-obesity medications, endoscopic procedures, and the refining of behavioral and surgical interventions.”
An assistant professor of medicine (endocrinology) and of pediatrics (endocrinology) at Yale School of Medicine, Dr. Jastrebroff says one of her goals is to conduct clinic research that will lead to better treatments for obesity and also have a clear public health impact in mitigating the obesity “pandemic.”
Titles
- Associate Professor
- Director, Weight Management & Obesity Prevention
- Medical Director, Yale Stress Center
Education & Training
- Clinical Research ScholarYale University School of Medicine (2013)
- PhDYale University Graduate School of Arts and Sciences (2011)
- Endocrinology Postdoctoral FellowshipYale University (2011)
- Pediatric Endocrinology Postdoctoral FellowshipYale University (2011)
- Chief ResidentUniversity of Maryland (2006)
- ResidencyUniversity of Maryland School of Medicine (2006)
- MDUniversity of Maryland at Baltimore (2002)
- BABucknell University, Art History (1998)
Additional Information
- Young Physician-Scientist Award: American Association for Clinical Investigation (ASCI) (2013)
- First Place Poster Award, Yale Multi-Disciplinary Endocrinology & Metabolism Retreat: Yale Univeristy (2013)
- American Diabetes Association Young Investigator Travel Grant Award: American Diabetes Association (ADA) (2013)
- Burroughs Wellcome Fund Travel Award, Translational Science Meeting 2013: Burroughs Wellcome Fund (2013)
- Translational Science Poster Award : Association for Clinical Research Training and Society for Clinical and Translational Science (2013)
- Diabetes Endocrinology Research Center (DRC), Poster Awardee: Yale University (2011)
- Yale Pediatric Fellows’ Research Day, Oral presentation award winner: Yale University (2011)
- AB of Obesity Medicine, Obesity Medicine (2016)
- WTNH (Channel 8) (2020): WTNH (Channel 8) On Call: Keto Diet – TV interview on news station: https://www.wtnh.com/news/health/news-8-on-call-keto-diet/
- WTNH (Channel 8) (2020): WTNH (Channel 8). Top 3 dieting trends of 2020. Live TV interview on news station: https://www.wtnh.com/on-air/gmct-at-nine/top-3-dieting-trends-of-2020/
- Better Health (2019): Better Health. 12 diets you should never try, according to health experts. https://www.eatthis.com/unhealthiest-diets-experts/
- Better Health (2019): Better Health. Healthy gifts that are doctor recommended. https://www.eatthis.com/healthy-gifts/
- WTNH (Channel 8) (2019): WTNH (Channel 8) On Call: New policy for children with severe obesity – TV interview on news station: https://www.wtnh.com/lifestyle/health-news/news-8-on-call-new-policy-for-children-with-severe-obesity/
- Huffington Post (2019): Huffington Post. This is your body on Keto. https://www.huffpost.com/entry/keto-effects-body_l_5d9b58abe4b099389803e441
- Health Central (2019): Health Central. When diet and exercise aren’t enough. https://www.healthcentral.com/article/obesity-treatments
- WTNH (Channel 8) (2019): WTNH (Channel 8) Dealing with Diabetes on Campus – Live TV interview on news station: https://www.wtnh.com/on-air/dealing-with-diabetes-on-campus/
- ADA (American Diabetes Association) (2019 - Present): Obesity/Pathogenesis of Obesity Subcommittee
- NIH (2019): NIH Study Section ad hoc reviewer KNOD: Kidney, Nutrition, Obesity, and Diabetes
- Jastreboff AM, Aronne LJ, Ahmad NN, Wharton S, Connery L, Alves B, Kiyosue A, Zhang S, Liu B, Bunck MC, Stefanski A. Tirzepatide Once Weekly for the Treatment of Obesity. The New England Journal Of Medicine 2022, 387: 205-216. PMID: 35658024, DOI: 10.1056/NEJMoa2206038.
- Fogelman N, Schwartz J, Chaplin TM, Jastreboff AM, Silverman WK, Sinha R. Parent Stress and Trauma, Autonomic Responses, and Negative Child Behaviors. Child Psychiatry And Human Development 2022 PMID: 35674991, DOI: 10.1007/s10578-022-01377-w.
- Asch RH, Holmes SE, Jastreboff AM, Potenza MN, Baldassarri SR, Carson RE, Pietrzak RH, Esterlis I. Lower synaptic density is associated with psychiatric and cognitive alterations in obesity. Neuropsychopharmacology : Official Publication Of The American College Of Neuropsychopharmacology 2022, 47: 543-552. PMID: 34294874, PMCID: PMC8674236, DOI: 10.1038/s41386-021-01111-5.
- Chouairi F, Milner A, Sen S, Guha A, Stewart J, Jastreboff AM, Mori M, Clark KA, Miller PE, Fuery MA, Rogers JG, Notarianni A, Jacoby D, Maulion C, Anwer M, Geirsson A, Desai NR, Ahmad T, Mullan CW. Impact of Obesity on Heart Transplantation Outcomes. Journal Of The American Heart Association 2021, 10: e021346. PMID: 34854316, PMCID: PMC9075353, DOI: 10.1161/JAHA.121.021346.
- Gossmann M, Butsch WS, Jastreboff AM. Treating the Chronic Disease of Obesity. The Medical Clinics Of North America 2021, 105: 983-1016. PMID: 34688422, DOI: 10.1016/j.mcna.2021.06.005.
- Butsch WS, Hajduk A, Cardel MI, Donahoo WT, Kyle TK, Stanford FC, Zeltser LM, Kotz CM, Jastreboff AM. COVID-19 vaccines are effective in people with obesity: A position statement from The Obesity Society. Obesity (Silver Spring, Md.) 2021, 29: 1575-1579. PMID: 34212511, PMCID: PMC8441899, DOI: 10.1002/oby.23251.
- Jebeile H, Cardel MI, Kyle TK, Jastreboff AM. Addressing psychosocial health in the treatment and care of adolescents with obesity. Obesity (Silver Spring, Md.) 2021, 29: 1413-1422. PMID: 34431234, DOI: 10.1002/oby.23194.
- Kidambi S, Batsis JA, Donahoo WT, Jastreboff AM, Kahan S, Saunders KH, Heymsfield SB. Dietary supplements and alternative therapies for obesity: A Perspective from The Obesity Society's Clinical Committee. Obesity (Silver Spring, Md.) 2021, 29: 1095-1098. PMID: 34159756, DOI: 10.1002/oby.23189.
- Angarita GA, Matuskey D, Pittman B, Costeines JL, Potenza MN, Jastreboff AM, Schmidt HD, Malison RT. Testing the effects of the GLP-1 receptor agonist exenatide on cocaine self-administration and subjective responses in humans with cocaine use disorder. Drug And Alcohol Dependence 2021, 221: 108614. PMID: 33621809, PMCID: PMC8026565, DOI: 10.1016/j.drugalcdep.2021.108614.
- Bini J, Bhatt S, Hillmer AT, Gallezot JD, Nabulsi N, Pracitto R, Labaree D, Kapinos M, Ropchan J, Matuskey D, Sherwin RS, Jastreboff AM, Carson RE, Cosgrove K, Huang Y. Body Mass Index and Age Effects on Brain 11β-Hydroxysteroid Dehydrogenase Type 1: a Positron Emission Tomography Study. Molecular Imaging And Biology : MIB : The Official Publication Of The Academy Of Molecular Imaging 2020, 22: 1124-1131. PMID: 32133575, PMCID: PMC7351613, DOI: 10.1007/s11307-020-01490-z.
- Monin JK, Sperduto CM, Manigault AW, Dutton A, Ali A, Clark MS, Jastreboff AM. Mindfulnes-Based Stress Reduction for Older Couples with Metabolic Syndrome: a Pilot Randomized Controlled Trial. Mindfulness 2020, 11: 917-927. PMID: 33343762, PMCID: PMC7748069, DOI: 10.1007/s12671-019-01301-9.
- Mindfulness Based Stress Reduction for Older Couples with Metabolic Syndrome: A Pilot Randomized Controlled TrialMonin JK, Sperduto M, Manigault A, Dutton A, Van Ness P, Ali A, Clark M, Jastreboff AM. Mindfulness Based Stress Reduction for Older Couples with Metabolic Syndrome: A Pilot Randomized Controlled Trial. Mindfulness. Jan 15, 2020.
- Body Mass Index and Age Effects on Brain 11β-Hydroxysteroid Dehydrogenase Type 1: A Positron Emission Tomography StudyBini J , Bhatt S, Hillmer A, Gallezot JD, Nabulsi N, Pracitto R, Labaree D, Kapinos M, Ropchan J, Matuskey D, Sherwin R, Jastreboff AM, Carson RE, Cosgrove K, Huang Y. Journal Molecular Imaging and Biology. Accepted for publication February 20, 2020
- Cardel MI, Jastreboff AM, Kelly AS. Treatment of Adolescent Obesity in 2020. JAMA 2019, 322: 1707-1708. PMID: 31566652, PMCID: PMC7268517, DOI: 10.1001/jama.2019.14725.
- Garvey WT, Jastreboff AM. COMMENTARY FROM THE AMERICAN ASSOCIATION OF CLINICAL ENDOCRINOLOGISTS ON THE U.S. PREVENTIVE SERVICES TASK FORCE RECOMMANDATIONS REGARDING WEIGHT LOSS INTERVENTIONS. Endocrine Practice : Official Journal Of The American College Of Endocrinology And The American Association Of Clinical Endocrinologists 2019, 25: 394-395. PMID: 31013160, DOI: 10.4158/EP-2018-0597.
- Srivastava G, Fox CK, Kelly AS, Jastreboff AM, Browne AF, Browne NT, Pratt JSA, Bolling C, Michalsky MP, Cook S, Lenders CM, Apovian CM. Clinical Considerations Regarding the Use of Obesity Pharmacotherapy in Adolescents with Obesity. Obesity (Silver Spring, Md.) 2019, 27: 190-204. PMID: 30677262, PMCID: PMC6449849, DOI: 10.1002/oby.22385.
- Jastreboff AM, Kotz CM, Kahan S, Kelly AS, Heymsfield SB. Obesity as a Disease: The Obesity Society 2018 Position Statement. Obesity (Silver Spring, Md.) 2019, 27: 7-9. PMID: 30569641, DOI: 10.1002/oby.22378.
- Jastreboff AM, Chaplin TM, Finnie S, Savoye M, Stults-Kolehmainen M, Silverman WK, Sinha R. Preventing Childhood Obesity Through a Mindfulness-Based Parent Stress Intervention: A Randomized Pilot Study. The Journal Of Pediatrics 2018, 202: 136-142.e1. PMID: 30241766, PMCID: PMC6203652, DOI: 10.1016/j.jpeds.2018.07.011.
- Doyle EA, Quinn SM, Ambrosino JM, Weyman K, Tamborlane WV, Jastreboff AM. Disordered Eating Behaviors in Emerging Adults With Type 1 Diabetes: A Common Problem for Both Men and Women. Journal Of Pediatric Health Care : Official Publication Of National Association Of Pediatric Nurse Associates & Practitioners 2017, 31: 327-333. PMID: 27843015, DOI: 10.1016/j.pedhc.2016.10.004.
- Chao AM, Jastreboff AM, White MA, Grilo CM, Sinha R. Stress, cortisol, and other appetite-related hormones: Prospective prediction of 6-month changes in food cravings and weight. Obesity (Silver Spring, Md.) 2017, 25: 713-720. PMID: 28349668, PMCID: PMC5373497, DOI: 10.1002/oby.21790.
- Gaiser EC, Gallezot JD, Worhunsky PD, Jastreboff AM, Pittman B, Kantrovitz L, Angarita GA, Cosgrove KP, Potenza MN, Malison RT, Carson RE, Matuskey D. Elevated Dopamine D2/3 Receptor Availability in Obese Individuals: A PET Imaging Study with [11C](+)PHNO. Neuropsychopharmacology : Official Publication Of The American College Of Neuropsychopharmacology 2016, 41: 3042-3050. PMID: 27374277, PMCID: PMC5101552, DOI: 10.1038/npp.2016.115.
- Quinn SM, Ambrosino JM, Doyle EA, Weyman K, Tamborlane WV, Jastreboff AM. UTILITY OF PSYCHOLOGICAL SCREENING OF YOUNG ADULTS WITH TYPE 1 DIABETES TRANSITIONING TO ADULT PROVIDERS. Endocrine Practice : Official Journal Of The American College Of Endocrinology And The American Association Of Clinical Endocrinologists 2016, 22: 1104-10. PMID: 27295017, DOI: 10.4158/EP151190.OR.
- Garrison KA, Sinha R, Lacadie CM, Scheinost D, Jastreboff AM, Constable RT, Potenza MN. Functional Connectivity During Exposure to Favorite-Food, Stress, and Neutral-Relaxing Imagery Differs Between Smokers and Nonsmokers. Nicotine & Tobacco Research : Official Journal Of The Society For Research On Nicotine And Tobacco 2016, 18: 1820-9. PMID: 26995796, PMCID: PMC4978981, DOI: 10.1093/ntr/ntw088.
- Jastreboff AM, Sinha R, Arora J, Giannini C, Kubat J, Malik S, Van Name MA, Santoro N, Savoye M, Duran EJ, Pierpont B, Cline G, Constable RT, Sherwin RS, Caprio S. Altered Brain Response to Drinking Glucose and Fructose in Obese Adolescents. Diabetes 2016, 65: 1929-39. PMID: 27207544, PMCID: PMC5384636, DOI: 10.2337/db15-1216.
- Garvey WT, Mechanick JI, Brett EM, Garber AJ, Hurley DL, Jastreboff AM, Nadolsky K, Pessah-Pollack R, Plodkowski R. AMERICAN ASSOCIATION OF CLINICAL ENDOCRINOLOGISTS AND AMERICAN COLLEGE OF ENDOCRINOLOGY COMPREHENSIVE CLINICAL PRACTICE GUIDELINES FOR MEDICAL CARE OF PATIENTS WITH OBESITY. Endocrine Practice : Official Journal Of The American College Of Endocrinology And The American Association Of Clinical Endocrinologists 2016, 22 Suppl 3: 1-203. PMID: 27219496, DOI: 10.4158/EP161365.GL.
- Garvey WT, Mechanick JI, Brett EM, Garber AJ, Hurley DL, Jastreboff AM, Nadolsky K, Pessah-Pollack R, Plodkowski R. AMERICAN ASSOCIATION OF CLINICAL ENDOCRINOLOGISTS AND AMERICAN COLLEGE OF ENDOCRINOLOGY COMPREHENSIVE CLINICAL PRACTICE GUIDELINES FOR MEDICAL CARE OF PATIENTS WITH OBESITYEXECUTIVE SUMMARYComplete Guidelines available at https://www.aace.com/publications/guidelines. Endocrine Practice : Official Journal Of The American College Of Endocrinology And The American Association Of Clinical Endocrinologists 2016, 22: 842-84. PMID: 27472012, DOI: 10.4158/EP161356.ESGL.
- Van Name M, Giannini C, Santoro N, Jastreboff AM, Kubat J, Li F, Kursawe R, Savoye M, Duran E, Dziura J, Sinha R, Sherwin RS, Cline G, Caprio S. Blunted suppression of acyl-ghrelin in response to fructose ingestion in obese adolescents: the role of insulin resistance. Obesity (Silver Spring, Md.) 2015, 23: 653-61. PMID: 25645909, PMCID: PMC4548801, DOI: 10.1002/oby.21019.
- Jastreboff AM, Sinha R, Lacadie CM, Balodis IM, Sherwin R, Potenza MN. Blunted striatal responses to favorite-food cues in smokers. Drug And Alcohol Dependence 2015, 146: 103-6. PMID: 25444233, PMCID: PMC4272899, DOI: 10.1016/j.drugalcdep.2014.09.006.
- Hooked on Sugar? Effect of Sucrose on Stress-Induced Cortisol ReleaseJastreboff AM. Hooked on Sugar? Effect of Sucrose on Stress-Induced Cortisol Release. PracticeUpdate website. Available at: http://www.practiceupdate.com/c/24494/48/8. Accessed May 18, 2015.
- Jastreboff AM, Lacadie C, Seo D, Kubat J, Van Name MA, Giannini C, Savoye M, Constable RT, Sherwin RS, Caprio S, Sinha R. Leptin is associated with exaggerated brain reward and emotion responses to food images in adolescent obesity. Diabetes Care 2014, 37: 3061-8. PMID: 25139883, PMCID: PMC4207200, DOI: 10.2337/dc14-0525.
- Jastreboff AM, Gaiser EC, Gu P, Sinha R. Sex differences in the association between dietary restraint, insulin resistance and obesity. Eating Behaviors 2014, 15: 286-90. PMID: 24854820, PMCID: PMC4032476, DOI: 10.1016/j.eatbeh.2014.03.008.
- Phentermine/Topiramate and Lifestyle Modification Effective for Weight Loss in DiabeticsJastreboff AM. Phentermine/Topiramate and Lifestyle Modification Effective for Weight Loss in Diabetics. Editorial. PracticeUpdate website. Available at: http://www.practiceupdate.com/journalscan/14806. Accessed December 22, 2014.
- Bariatric Surgery-Induced Weight Loss Causes Remission of Food Addiction in Extreme ObesityJastreboff AM. Bariatric Surgery-Induced Weight Loss Causes Remission of Food Addiction in Extreme Obesity. Editorial. PracticeUpdate website. Available at: http://www.practiceupdate.com/journalscan/11791. Accessed August 19, 2014.
- Insulin: Food for ThoughtJastreboff AM. Insulin: Food for Thought. Science Translational Medicine. Vol. 6, Issue 226, p. 226ec39. March 2014. DOI: 10.1126/scitranslmed.3008712
- Sinha R, Jastreboff AM. Stress as a common risk factor for obesity and addiction. Biological Psychiatry 2013, 73: 827-35. PMID: 23541000, PMCID: PMC3658316, DOI: 10.1016/j.biopsych.2013.01.032.
- Hairston KG, Ducharme JL, Treuth MS, Hsueh WC, Jastreboff AM, Ryan KA, Shi X, Mitchell BD, Shuldiner AR, Snitker S. Comparison of BMI and physical activity between old order Amish children and non-Amish children. Diabetes Care 2013, 36: 873-8. PMID: 23093661, PMCID: PMC3609522, DOI: 10.2337/dc12-0934.
- Jastreboff AM, Sinha R, Lacadie C, Small DM, Sherwin RS, Potenza MN. Neural correlates of stress- and food cue-induced food craving in obesity: association with insulin levels. Diabetes Care 2013, 36: 394-402. PMID: 23069840, PMCID: PMC3554293, DOI: 10.2337/dc12-1112.
- Diabetes Shrinks the BrainJastreboff AM. Diabetes Shrinks the Brain. Science Translational Medicine. Vol. 5, Issue 214, p.214ec199. December 2013. DOI: 10.1126/scitranslmed.3008073
- Oxytocin Curbs Cookie ConsumptionJastreboff AM. Oxytocin Curbs Cookie Consumption. Science Translational Medicine. Vol. 5, Issue 208, p. 208ec173. October 2013. DOI: 10.1126/scitranslamed.3007768
- BAT Burns Fat? CoolJastreboff AM. BAT Burns Fat? Cool. Science Translational Medicine. Vol. 5, Issue 202, p. 202ec148. September 2013. DOI: 10.1126/scitranslmed.3007485
- Linking an Obesity-Associated Gene Variant, Ghrelin, and the BrainJastreboff AM. Linking an Obesity-Associated Gene Variant, Ghrelin, and the Brain. Science Translational Medicine. 2013 July 31; Vol 5, Issue 196, p. 184ec124. DOI: 10.1126/scitranslmed.3007044
- The brains behind alcohol relapseJastreboff AM. The brains behind alcohol relapse. Science Translational Medicine. Vol. 5, Issue 185, p. 185ec82. May 2013. DOI: 10.1126/scitranslmed.300652
- Demystifying the “magical cure” for diabetesJastreboff AM. Demystifying the “magical cure” for diabetes. Science Translational Medicine. Vol. 5, Issue 184, p. 184ec76. May 2013. DOI: 10.1126/scitranslmed.3006449
- Paying our sleep debt in extra poundsJastreboff AM. Paying our sleep debt in extra pounds. Science Translational Medicine.5:178. March 2013. DOI: 10.1126/scitranslmed.3006149
- Sherwin R, Jastreboff AM. Year in diabetes 2012: The diabetes tsunami. The Journal Of Clinical Endocrinology And Metabolism 2012, 97: 4293-301. PMID: 23185035, PMCID: PMC3513534, DOI: 10.1210/jc.2012-3487.
- Phipps MS, Jastreboff AM, Furie K, Kernan WN. The diagnosis and management of cerebrovascular disease in diabetes. Current Diabetes Reports 2012, 12: 314-23. PMID: 22492061, DOI: 10.1007/s11892-012-0271-x.
- Jastreboff AM, Potenza MN, Lacadie C, Hong KA, Sherwin RS, Sinha R. Body mass index, metabolic factors, and striatal activation during stressful and neutral-relaxing states: an FMRI study. Neuropsychopharmacology : Official Publication Of The American College Of Neuropsychopharmacology 2011, 36: 627-37. PMID: 21048702, PMCID: PMC3055687, DOI: 10.1038/npp.2010.194.
- Jastreboff A, Sherr J. Three faces of hypothalamic tumors. Journal Of Pediatric Endocrinology & Metabolism : JPEM 2007, 20: 471. PMID: 17550209, DOI: 10.1515/jpem.2007.20.4.471.
- Jastreboff AM, Cymet T. Role of the human papilloma virus in the development of cervical intraepithelial neoplasia and malignancy. Postgraduate Medical Journal 2002, 78: 225-8. PMID: 11930025, PMCID: PMC1742321.
- Jastreboff AM. Paying our sleep debt in extra pounds. Science Translational Medicine.5:178. March 2013. DOI: 10.1126/scitranslmed.3006149Jastreboff AM. Paying our sleep debt in extra pounds. Science Translational Medicine.5:178. March 2013. DOI: 10.1126/scitranslmed.3006149
- Jastreboff AM. Demystifying the “magical cure” for diabetes. Science Translational Medicine. Vol. 5, Issue 184, p. 184ec76. May 2013. DOI: 10.1126/scitranslmed.3006449Jastreboff AM. Demystifying the “magical cure” for diabetes. Science Translational Medicine. Vol. 5, Issue 184, p. 184ec76. May 2013. DOI: 10.1126/scitranslmed.3006449
- Jastreboff AM. BAT Burns Fat? Cool. Science Translational Medicine. Vol. 5, Issue 202, p. 202ec148. September 2013. DOI: 10.1126/scitranslmed.3007485Jastreboff AM. BAT Burns Fat? Cool. Science Translational Medicine. Vol. 5, Issue 202, p. 202ec148. September 2013. DOI: 10.1126/scitranslmed.3007485
- Jastreboff AM. Oxytocin Curbs Cookie Consumption. Science Translational Medicine. Vol. 5, Issue 208, p. 208ec173. October 2013. DOI: 10.1126/scitranslamed.3007768Jastreboff AM. Oxytocin Curbs Cookie Consumption. Science Translational Medicine. Vol. 5, Issue 208, p. 208ec173. October 2013. DOI: 10.1126/scitranslamed.3007768
- Yale Pediatric Endocrinology1 Long Wharf DriveNew Haven, CT 06511
- Yale Diabetes ClinicDana Clinic Building789 Howard Avenue, Ste 2nd FloorNew Haven, CT 06519
Biography
Ania M. Jastreboff, MD, PhD, is an adult and pediatric endocrinologist with expertise in obesity medicine and weight management. She cares for patients who have prediabetes, insulin resistance, metabolic syndrome, and type 1 and type 2 diabetes.
Dr. Jastrebroff says she emphathizes with patients who struggle to lose weight or maintain weight loss. “Carrying excess weight and having obesity is not a lifestyle choice. Obesity is a chronic disease and should be treated with the same vigor and integrity as other chronic diseases,” she says. “We are in the infancy of our understanding of the mechanisms that underlie obesity. Many novel treatments are under development, including new anti-obesity medications, endoscopic procedures, and the refining of behavioral and surgical interventions.”
An assistant professor of medicine (endocrinology) and of pediatrics (endocrinology) at Yale School of Medicine, Dr. Jastrebroff says one of her goals is to conduct clinic research that will lead to better treatments for obesity and also have a clear public health impact in mitigating the obesity “pandemic.”
Titles
- Associate Professor
- Director, Weight Management & Obesity Prevention
- Medical Director, Yale Stress Center
Education & Training
- Clinical Research ScholarYale University School of Medicine (2013)
- PhDYale University Graduate School of Arts and Sciences (2011)
- Endocrinology Postdoctoral FellowshipYale University (2011)
- Pediatric Endocrinology Postdoctoral FellowshipYale University (2011)
- Chief ResidentUniversity of Maryland (2006)
- ResidencyUniversity of Maryland School of Medicine (2006)
- MDUniversity of Maryland at Baltimore (2002)
- BABucknell University, Art History (1998)
Additional Information
- Young Physician-Scientist Award: American Association for Clinical Investigation (ASCI) (2013)
- First Place Poster Award, Yale Multi-Disciplinary Endocrinology & Metabolism Retreat: Yale Univeristy (2013)
- American Diabetes Association Young Investigator Travel Grant Award: American Diabetes Association (ADA) (2013)
- Burroughs Wellcome Fund Travel Award, Translational Science Meeting 2013: Burroughs Wellcome Fund (2013)
- Translational Science Poster Award : Association for Clinical Research Training and Society for Clinical and Translational Science (2013)
- Diabetes Endocrinology Research Center (DRC), Poster Awardee: Yale University (2011)
- Yale Pediatric Fellows’ Research Day, Oral presentation award winner: Yale University (2011)
- AB of Obesity Medicine, Obesity Medicine (2016)
- WTNH (Channel 8) (2020): WTNH (Channel 8) On Call: Keto Diet – TV interview on news station: https://www.wtnh.com/news/health/news-8-on-call-keto-diet/
- WTNH (Channel 8) (2020): WTNH (Channel 8). Top 3 dieting trends of 2020. Live TV interview on news station: https://www.wtnh.com/on-air/gmct-at-nine/top-3-dieting-trends-of-2020/
- Better Health (2019): Better Health. 12 diets you should never try, according to health experts. https://www.eatthis.com/unhealthiest-diets-experts/
- Better Health (2019): Better Health. Healthy gifts that are doctor recommended. https://www.eatthis.com/healthy-gifts/
- WTNH (Channel 8) (2019): WTNH (Channel 8) On Call: New policy for children with severe obesity – TV interview on news station: https://www.wtnh.com/lifestyle/health-news/news-8-on-call-new-policy-for-children-with-severe-obesity/
- Huffington Post (2019): Huffington Post. This is your body on Keto. https://www.huffpost.com/entry/keto-effects-body_l_5d9b58abe4b099389803e441
- Health Central (2019): Health Central. When diet and exercise aren’t enough. https://www.healthcentral.com/article/obesity-treatments
- WTNH (Channel 8) (2019): WTNH (Channel 8) Dealing with Diabetes on Campus – Live TV interview on news station: https://www.wtnh.com/on-air/dealing-with-diabetes-on-campus/
- ADA (American Diabetes Association) (2019 - Present): Obesity/Pathogenesis of Obesity Subcommittee
- NIH (2019): NIH Study Section ad hoc reviewer KNOD: Kidney, Nutrition, Obesity, and Diabetes
- Jastreboff AM, Aronne LJ, Ahmad NN, Wharton S, Connery L, Alves B, Kiyosue A, Zhang S, Liu B, Bunck MC, Stefanski A. Tirzepatide Once Weekly for the Treatment of Obesity. The New England Journal Of Medicine 2022, 387: 205-216. PMID: 35658024, DOI: 10.1056/NEJMoa2206038.
- Fogelman N, Schwartz J, Chaplin TM, Jastreboff AM, Silverman WK, Sinha R. Parent Stress and Trauma, Autonomic Responses, and Negative Child Behaviors. Child Psychiatry And Human Development 2022 PMID: 35674991, DOI: 10.1007/s10578-022-01377-w.
- Asch RH, Holmes SE, Jastreboff AM, Potenza MN, Baldassarri SR, Carson RE, Pietrzak RH, Esterlis I. Lower synaptic density is associated with psychiatric and cognitive alterations in obesity. Neuropsychopharmacology : Official Publication Of The American College Of Neuropsychopharmacology 2022, 47: 543-552. PMID: 34294874, PMCID: PMC8674236, DOI: 10.1038/s41386-021-01111-5.
- Chouairi F, Milner A, Sen S, Guha A, Stewart J, Jastreboff AM, Mori M, Clark KA, Miller PE, Fuery MA, Rogers JG, Notarianni A, Jacoby D, Maulion C, Anwer M, Geirsson A, Desai NR, Ahmad T, Mullan CW. Impact of Obesity on Heart Transplantation Outcomes. Journal Of The American Heart Association 2021, 10: e021346. PMID: 34854316, PMCID: PMC9075353, DOI: 10.1161/JAHA.121.021346.
- Gossmann M, Butsch WS, Jastreboff AM. Treating the Chronic Disease of Obesity. The Medical Clinics Of North America 2021, 105: 983-1016. PMID: 34688422, DOI: 10.1016/j.mcna.2021.06.005.
- Butsch WS, Hajduk A, Cardel MI, Donahoo WT, Kyle TK, Stanford FC, Zeltser LM, Kotz CM, Jastreboff AM. COVID-19 vaccines are effective in people with obesity: A position statement from The Obesity Society. Obesity (Silver Spring, Md.) 2021, 29: 1575-1579. PMID: 34212511, PMCID: PMC8441899, DOI: 10.1002/oby.23251.
- Jebeile H, Cardel MI, Kyle TK, Jastreboff AM. Addressing psychosocial health in the treatment and care of adolescents with obesity. Obesity (Silver Spring, Md.) 2021, 29: 1413-1422. PMID: 34431234, DOI: 10.1002/oby.23194.
- Kidambi S, Batsis JA, Donahoo WT, Jastreboff AM, Kahan S, Saunders KH, Heymsfield SB. Dietary supplements and alternative therapies for obesity: A Perspective from The Obesity Society's Clinical Committee. Obesity (Silver Spring, Md.) 2021, 29: 1095-1098. PMID: 34159756, DOI: 10.1002/oby.23189.
- Angarita GA, Matuskey D, Pittman B, Costeines JL, Potenza MN, Jastreboff AM, Schmidt HD, Malison RT. Testing the effects of the GLP-1 receptor agonist exenatide on cocaine self-administration and subjective responses in humans with cocaine use disorder. Drug And Alcohol Dependence 2021, 221: 108614. PMID: 33621809, PMCID: PMC8026565, DOI: 10.1016/j.drugalcdep.2021.108614.
- Bini J, Bhatt S, Hillmer AT, Gallezot JD, Nabulsi N, Pracitto R, Labaree D, Kapinos M, Ropchan J, Matuskey D, Sherwin RS, Jastreboff AM, Carson RE, Cosgrove K, Huang Y. Body Mass Index and Age Effects on Brain 11β-Hydroxysteroid Dehydrogenase Type 1: a Positron Emission Tomography Study. Molecular Imaging And Biology : MIB : The Official Publication Of The Academy Of Molecular Imaging 2020, 22: 1124-1131. PMID: 32133575, PMCID: PMC7351613, DOI: 10.1007/s11307-020-01490-z.
- Monin JK, Sperduto CM, Manigault AW, Dutton A, Ali A, Clark MS, Jastreboff AM. Mindfulnes-Based Stress Reduction for Older Couples with Metabolic Syndrome: a Pilot Randomized Controlled Trial. Mindfulness 2020, 11: 917-927. PMID: 33343762, PMCID: PMC7748069, DOI: 10.1007/s12671-019-01301-9.
- Mindfulness Based Stress Reduction for Older Couples with Metabolic Syndrome: A Pilot Randomized Controlled TrialMonin JK, Sperduto M, Manigault A, Dutton A, Van Ness P, Ali A, Clark M, Jastreboff AM. Mindfulness Based Stress Reduction for Older Couples with Metabolic Syndrome: A Pilot Randomized Controlled Trial. Mindfulness. Jan 15, 2020.
- Body Mass Index and Age Effects on Brain 11β-Hydroxysteroid Dehydrogenase Type 1: A Positron Emission Tomography StudyBini J , Bhatt S, Hillmer A, Gallezot JD, Nabulsi N, Pracitto R, Labaree D, Kapinos M, Ropchan J, Matuskey D, Sherwin R, Jastreboff AM, Carson RE, Cosgrove K, Huang Y. Journal Molecular Imaging and Biology. Accepted for publication February 20, 2020
- Cardel MI, Jastreboff AM, Kelly AS. Treatment of Adolescent Obesity in 2020. JAMA 2019, 322: 1707-1708. PMID: 31566652, PMCID: PMC7268517, DOI: 10.1001/jama.2019.14725.
- Garvey WT, Jastreboff AM. COMMENTARY FROM THE AMERICAN ASSOCIATION OF CLINICAL ENDOCRINOLOGISTS ON THE U.S. PREVENTIVE SERVICES TASK FORCE RECOMMANDATIONS REGARDING WEIGHT LOSS INTERVENTIONS. Endocrine Practice : Official Journal Of The American College Of Endocrinology And The American Association Of Clinical Endocrinologists 2019, 25: 394-395. PMID: 31013160, DOI: 10.4158/EP-2018-0597.
- Srivastava G, Fox CK, Kelly AS, Jastreboff AM, Browne AF, Browne NT, Pratt JSA, Bolling C, Michalsky MP, Cook S, Lenders CM, Apovian CM. Clinical Considerations Regarding the Use of Obesity Pharmacotherapy in Adolescents with Obesity. Obesity (Silver Spring, Md.) 2019, 27: 190-204. PMID: 30677262, PMCID: PMC6449849, DOI: 10.1002/oby.22385.
- Jastreboff AM, Kotz CM, Kahan S, Kelly AS, Heymsfield SB. Obesity as a Disease: The Obesity Society 2018 Position Statement. Obesity (Silver Spring, Md.) 2019, 27: 7-9. PMID: 30569641, DOI: 10.1002/oby.22378.
- Jastreboff AM, Chaplin TM, Finnie S, Savoye M, Stults-Kolehmainen M, Silverman WK, Sinha R. Preventing Childhood Obesity Through a Mindfulness-Based Parent Stress Intervention: A Randomized Pilot Study. The Journal Of Pediatrics 2018, 202: 136-142.e1. PMID: 30241766, PMCID: PMC6203652, DOI: 10.1016/j.jpeds.2018.07.011.
- Doyle EA, Quinn SM, Ambrosino JM, Weyman K, Tamborlane WV, Jastreboff AM. Disordered Eating Behaviors in Emerging Adults With Type 1 Diabetes: A Common Problem for Both Men and Women. Journal Of Pediatric Health Care : Official Publication Of National Association Of Pediatric Nurse Associates & Practitioners 2017, 31: 327-333. PMID: 27843015, DOI: 10.1016/j.pedhc.2016.10.004.
- Chao AM, Jastreboff AM, White MA, Grilo CM, Sinha R. Stress, cortisol, and other appetite-related hormones: Prospective prediction of 6-month changes in food cravings and weight. Obesity (Silver Spring, Md.) 2017, 25: 713-720. PMID: 28349668, PMCID: PMC5373497, DOI: 10.1002/oby.21790.
- Gaiser EC, Gallezot JD, Worhunsky PD, Jastreboff AM, Pittman B, Kantrovitz L, Angarita GA, Cosgrove KP, Potenza MN, Malison RT, Carson RE, Matuskey D. Elevated Dopamine D2/3 Receptor Availability in Obese Individuals: A PET Imaging Study with [11C](+)PHNO. Neuropsychopharmacology : Official Publication Of The American College Of Neuropsychopharmacology 2016, 41: 3042-3050. PMID: 27374277, PMCID: PMC5101552, DOI: 10.1038/npp.2016.115.
- Quinn SM, Ambrosino JM, Doyle EA, Weyman K, Tamborlane WV, Jastreboff AM. UTILITY OF PSYCHOLOGICAL SCREENING OF YOUNG ADULTS WITH TYPE 1 DIABETES TRANSITIONING TO ADULT PROVIDERS. Endocrine Practice : Official Journal Of The American College Of Endocrinology And The American Association Of Clinical Endocrinologists 2016, 22: 1104-10. PMID: 27295017, DOI: 10.4158/EP151190.OR.
- Garrison KA, Sinha R, Lacadie CM, Scheinost D, Jastreboff AM, Constable RT, Potenza MN. Functional Connectivity During Exposure to Favorite-Food, Stress, and Neutral-Relaxing Imagery Differs Between Smokers and Nonsmokers. Nicotine & Tobacco Research : Official Journal Of The Society For Research On Nicotine And Tobacco 2016, 18: 1820-9. PMID: 26995796, PMCID: PMC4978981, DOI: 10.1093/ntr/ntw088.
- Jastreboff AM, Sinha R, Arora J, Giannini C, Kubat J, Malik S, Van Name MA, Santoro N, Savoye M, Duran EJ, Pierpont B, Cline G, Constable RT, Sherwin RS, Caprio S. Altered Brain Response to Drinking Glucose and Fructose in Obese Adolescents. Diabetes 2016, 65: 1929-39. PMID: 27207544, PMCID: PMC5384636, DOI: 10.2337/db15-1216.
- Garvey WT, Mechanick JI, Brett EM, Garber AJ, Hurley DL, Jastreboff AM, Nadolsky K, Pessah-Pollack R, Plodkowski R. AMERICAN ASSOCIATION OF CLINICAL ENDOCRINOLOGISTS AND AMERICAN COLLEGE OF ENDOCRINOLOGY COMPREHENSIVE CLINICAL PRACTICE GUIDELINES FOR MEDICAL CARE OF PATIENTS WITH OBESITY. Endocrine Practice : Official Journal Of The American College Of Endocrinology And The American Association Of Clinical Endocrinologists 2016, 22 Suppl 3: 1-203. PMID: 27219496, DOI: 10.4158/EP161365.GL.
- Garvey WT, Mechanick JI, Brett EM, Garber AJ, Hurley DL, Jastreboff AM, Nadolsky K, Pessah-Pollack R, Plodkowski R. AMERICAN ASSOCIATION OF CLINICAL ENDOCRINOLOGISTS AND AMERICAN COLLEGE OF ENDOCRINOLOGY COMPREHENSIVE CLINICAL PRACTICE GUIDELINES FOR MEDICAL CARE OF PATIENTS WITH OBESITYEXECUTIVE SUMMARYComplete Guidelines available at https://www.aace.com/publications/guidelines. Endocrine Practice : Official Journal Of The American College Of Endocrinology And The American Association Of Clinical Endocrinologists 2016, 22: 842-84. PMID: 27472012, DOI: 10.4158/EP161356.ESGL.
- Van Name M, Giannini C, Santoro N, Jastreboff AM, Kubat J, Li F, Kursawe R, Savoye M, Duran E, Dziura J, Sinha R, Sherwin RS, Cline G, Caprio S. Blunted suppression of acyl-ghrelin in response to fructose ingestion in obese adolescents: the role of insulin resistance. Obesity (Silver Spring, Md.) 2015, 23: 653-61. PMID: 25645909, PMCID: PMC4548801, DOI: 10.1002/oby.21019.
- Jastreboff AM, Sinha R, Lacadie CM, Balodis IM, Sherwin R, Potenza MN. Blunted striatal responses to favorite-food cues in smokers. Drug And Alcohol Dependence 2015, 146: 103-6. PMID: 25444233, PMCID: PMC4272899, DOI: 10.1016/j.drugalcdep.2014.09.006.
- Hooked on Sugar? Effect of Sucrose on Stress-Induced Cortisol ReleaseJastreboff AM. Hooked on Sugar? Effect of Sucrose on Stress-Induced Cortisol Release. PracticeUpdate website. Available at: http://www.practiceupdate.com/c/24494/48/8. Accessed May 18, 2015.
- Jastreboff AM, Lacadie C, Seo D, Kubat J, Van Name MA, Giannini C, Savoye M, Constable RT, Sherwin RS, Caprio S, Sinha R. Leptin is associated with exaggerated brain reward and emotion responses to food images in adolescent obesity. Diabetes Care 2014, 37: 3061-8. PMID: 25139883, PMCID: PMC4207200, DOI: 10.2337/dc14-0525.
- Jastreboff AM, Gaiser EC, Gu P, Sinha R. Sex differences in the association between dietary restraint, insulin resistance and obesity. Eating Behaviors 2014, 15: 286-90. PMID: 24854820, PMCID: PMC4032476, DOI: 10.1016/j.eatbeh.2014.03.008.
- Phentermine/Topiramate and Lifestyle Modification Effective for Weight Loss in DiabeticsJastreboff AM. Phentermine/Topiramate and Lifestyle Modification Effective for Weight Loss in Diabetics. Editorial. PracticeUpdate website. Available at: http://www.practiceupdate.com/journalscan/14806. Accessed December 22, 2014.
- Bariatric Surgery-Induced Weight Loss Causes Remission of Food Addiction in Extreme ObesityJastreboff AM. Bariatric Surgery-Induced Weight Loss Causes Remission of Food Addiction in Extreme Obesity. Editorial. PracticeUpdate website. Available at: http://www.practiceupdate.com/journalscan/11791. Accessed August 19, 2014.
- Insulin: Food for ThoughtJastreboff AM. Insulin: Food for Thought. Science Translational Medicine. Vol. 6, Issue 226, p. 226ec39. March 2014. DOI: 10.1126/scitranslmed.3008712
- Sinha R, Jastreboff AM. Stress as a common risk factor for obesity and addiction. Biological Psychiatry 2013, 73: 827-35. PMID: 23541000, PMCID: PMC3658316, DOI: 10.1016/j.biopsych.2013.01.032.
- Hairston KG, Ducharme JL, Treuth MS, Hsueh WC, Jastreboff AM, Ryan KA, Shi X, Mitchell BD, Shuldiner AR, Snitker S. Comparison of BMI and physical activity between old order Amish children and non-Amish children. Diabetes Care 2013, 36: 873-8. PMID: 23093661, PMCID: PMC3609522, DOI: 10.2337/dc12-0934.
- Jastreboff AM, Sinha R, Lacadie C, Small DM, Sherwin RS, Potenza MN. Neural correlates of stress- and food cue-induced food craving in obesity: association with insulin levels. Diabetes Care 2013, 36: 394-402. PMID: 23069840, PMCID: PMC3554293, DOI: 10.2337/dc12-1112.
- Diabetes Shrinks the BrainJastreboff AM. Diabetes Shrinks the Brain. Science Translational Medicine. Vol. 5, Issue 214, p.214ec199. December 2013. DOI: 10.1126/scitranslmed.3008073
- Oxytocin Curbs Cookie ConsumptionJastreboff AM. Oxytocin Curbs Cookie Consumption. Science Translational Medicine. Vol. 5, Issue 208, p. 208ec173. October 2013. DOI: 10.1126/scitranslamed.3007768
- BAT Burns Fat? CoolJastreboff AM. BAT Burns Fat? Cool. Science Translational Medicine. Vol. 5, Issue 202, p. 202ec148. September 2013. DOI: 10.1126/scitranslmed.3007485
- Linking an Obesity-Associated Gene Variant, Ghrelin, and the BrainJastreboff AM. Linking an Obesity-Associated Gene Variant, Ghrelin, and the Brain. Science Translational Medicine. 2013 July 31; Vol 5, Issue 196, p. 184ec124. DOI: 10.1126/scitranslmed.3007044
- The brains behind alcohol relapseJastreboff AM. The brains behind alcohol relapse. Science Translational Medicine. Vol. 5, Issue 185, p. 185ec82. May 2013. DOI: 10.1126/scitranslmed.300652
- Demystifying the “magical cure” for diabetesJastreboff AM. Demystifying the “magical cure” for diabetes. Science Translational Medicine. Vol. 5, Issue 184, p. 184ec76. May 2013. DOI: 10.1126/scitranslmed.3006449
- Paying our sleep debt in extra poundsJastreboff AM. Paying our sleep debt in extra pounds. Science Translational Medicine.5:178. March 2013. DOI: 10.1126/scitranslmed.3006149
- Sherwin R, Jastreboff AM. Year in diabetes 2012: The diabetes tsunami. The Journal Of Clinical Endocrinology And Metabolism 2012, 97: 4293-301. PMID: 23185035, PMCID: PMC3513534, DOI: 10.1210/jc.2012-3487.
- Phipps MS, Jastreboff AM, Furie K, Kernan WN. The diagnosis and management of cerebrovascular disease in diabetes. Current Diabetes Reports 2012, 12: 314-23. PMID: 22492061, DOI: 10.1007/s11892-012-0271-x.
- Jastreboff AM, Potenza MN, Lacadie C, Hong KA, Sherwin RS, Sinha R. Body mass index, metabolic factors, and striatal activation during stressful and neutral-relaxing states: an FMRI study. Neuropsychopharmacology : Official Publication Of The American College Of Neuropsychopharmacology 2011, 36: 627-37. PMID: 21048702, PMCID: PMC3055687, DOI: 10.1038/npp.2010.194.
- Jastreboff A, Sherr J. Three faces of hypothalamic tumors. Journal Of Pediatric Endocrinology & Metabolism : JPEM 2007, 20: 471. PMID: 17550209, DOI: 10.1515/jpem.2007.20.4.471.
- Jastreboff AM, Cymet T. Role of the human papilloma virus in the development of cervical intraepithelial neoplasia and malignancy. Postgraduate Medical Journal 2002, 78: 225-8. PMID: 11930025, PMCID: PMC1742321.
- Jastreboff AM. Paying our sleep debt in extra pounds. Science Translational Medicine.5:178. March 2013. DOI: 10.1126/scitranslmed.3006149Jastreboff AM. Paying our sleep debt in extra pounds. Science Translational Medicine.5:178. March 2013. DOI: 10.1126/scitranslmed.3006149
- Jastreboff AM. Demystifying the “magical cure” for diabetes. Science Translational Medicine. Vol. 5, Issue 184, p. 184ec76. May 2013. DOI: 10.1126/scitranslmed.3006449Jastreboff AM. Demystifying the “magical cure” for diabetes. Science Translational Medicine. Vol. 5, Issue 184, p. 184ec76. May 2013. DOI: 10.1126/scitranslmed.3006449
- Jastreboff AM. BAT Burns Fat? Cool. Science Translational Medicine. Vol. 5, Issue 202, p. 202ec148. September 2013. DOI: 10.1126/scitranslmed.3007485Jastreboff AM. BAT Burns Fat? Cool. Science Translational Medicine. Vol. 5, Issue 202, p. 202ec148. September 2013. DOI: 10.1126/scitranslmed.3007485
- Jastreboff AM. Oxytocin Curbs Cookie Consumption. Science Translational Medicine. Vol. 5, Issue 208, p. 208ec173. October 2013. DOI: 10.1126/scitranslamed.3007768Jastreboff AM. Oxytocin Curbs Cookie Consumption. Science Translational Medicine. Vol. 5, Issue 208, p. 208ec173. October 2013. DOI: 10.1126/scitranslamed.3007768
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- Yale Pediatric Endocrinology1 Long Wharf DriveNew Haven, CT 06511
- Yale Diabetes ClinicDana Clinic Building789 Howard Avenue, Ste 2nd FloorNew Haven, CT 06519