- Yale-New Haven Transplantation CenterYale Physicians Building800 Howard Avenue, Ste 3rd floorNew Haven, CT 06519
- Yale Transplant & ImmunologyFarnam Memorial Building310 Cedar StreetNew Haven, CT 06510
Sanjay Kulkarni, MD, MHCM, FACS
Biography
Sanjay Kulkarni, MD, is a multi-organ transplant surgeon and medical director of the Center for Living Organ Donors at Yale New Haven Hospital. In this role Dr. Kulkarni helped pioneer a unique initiative that is first in the United States of its kind. The Center for Living Organ Donors creates supportive communities of living donors and provides them with free, lifelong local medical monitoring for any health issues that may arise related to their organ donation.
“I think I have the best job in the world,” says Dr. Kulkarni. “I deal with living organ donors every single day—individuals who constantly remind you what a major difference one person’s generosity can make in another person’s life, and for the benefit of society.”
Dr. Kulkarni performs all living donor evaluations and 95 percent of kidney donor surgeries for Yale Medicine. He has played a role in such high-profile surgeries as Connecticut’s first eight-patient kidney transplant exchange in 2015. In this complex match-up, four women underwent surgery to give four men the kidneys they needed.
Dr. Kulkarni is also the surgical director of the Yale Medicine Kidney and Pancreas Transplant Program, a destination center for patients who need these transplants, and the largest program for both kidney transplantation and living-donor kidney transplantation in New England. Dr. Kulkarni and his colleagues in the program specialize in minimally invasive surgical approaches, which typically reduce pain and hasten recoveries.
An associate professor of transplant surgery and of nephrology at Yale School of Medicine, Dr. Kulkarni is also the scientific director of the Yale Transplant Research Unit, which pursues new therapies for transplant patients. His personal research explores the ethics surrounding care of living donors, understanding the reasons why some people come forward to be considered as a donor then opt out, and the use of social networking to foster donor communities.
Titles
- Professor of Surgery (Transplant)
- Physician Executive Director, Clinical Continuity & Integration, Yale-New Haven Hospital
- Surgical Director, Kidney Transplant Program
- Medical Director, New England Donor Services
- Medical Director, Center for Living Organ Donors
Education & Training
- MHCMHarvard University, School of Public Health (2018)
- Global Clinical Scholars Training Program (GCSRT)Harvard Medical School (2015)
- FellowUniversity of Chicago Hospitals, Chicago, IL (2004)
- FellowUniversity Hospital Essen, Germany (2004)
- Clinical Research Training Program (CRTP)University of Chicago, Pritzker School of Medicine (2004)
- Chief ResidentUniversity of Chicago Hospitals, Chicago, IL (2002)
- ResidentUniversity of Chicago Hospitals, Chicago, IL (2001)
- Research FellowUniversity of Chicago, Chicago, IL (1999)
- MDMedical College Wisconsin (1995)
- BSUniversity of Wisconsin (1990)
- Research FellowUniversity of Wisconsin-Madison, Madison, WI (1990)
Languages Spoken
- English
- Deutsch (German)
Additional Information
- AB of Surgery, Surgery, General (2003, recertified: 2012)
- UNOS (2020 - Present): Ethics Committee
- American Journal of Transplantation (2019 - Present): Associate Editor
- AASLD (2013 - 2015): AASLD, Liver & Intestive Committee
- UNOS (2013 - 2015): Region representative, UNOS Living Donor Committee
- Sun Z, Zhang Z, Banu K, Azzi YA, Reghuvaran A, Fredericks S, Planoutene M, Hartzell S, Kim Y, Pell J, Tietjen G, Asch W, Kulkarni S, Formica R, Rana M, Maltzman JS, Zhang W, Akalin E, Heeger PS, Cravedi P, Menon MC. Blood Transcriptomes of SARS-CoV-2-Infected Kidney Transplant Recipients Associated with Immune Insufficiency Proportionate to Severity. Journal Of The American Society Of Nephrology : JASN 2022 PMID: 36041788, DOI: 10.1681/ASN.2022010125.
- Kulkarni S, Glazier A, Lipkowitz G, Fynn-Tompson F, Woolley AE, Delmonico FL. A Collaborative Stewardship of OPOs and Transplant Centers to Maintain Equitable Allocation when Facilitating Ex Vivo Organ Preservation. American Journal Of Transplantation : Official Journal Of The American Society Of Transplantation And The American Society Of Transplant Surgeons 2022 PMID: 35704287, DOI: 10.1111/ajt.17120.
- Azar MM, Cohen E, Ma L, Cissé OH, Gan G, Deng Y, Belfield K, Asch W, Grant M, Gleeson S, Koff A, Gaston DC, Topal J, Curran S, Kulkarni S, Kovacs JA, Malinis M. Genetic and Epidemiologic Analyses of an Outbreak of Pneumocystis jirovecii Pneumonia Among Kidney Transplant Recipients in the United States. Clinical Infectious Diseases : An Official Publication Of The Infectious Diseases Society Of America 2022, 74: 639-647. PMID: 34017984, PMCID: PMC9012955, DOI: 10.1093/cid/ciab474.
- Kulkarni S, Flescher A, Ahmad M, Bayliss G, Bearl D, Biondi L, Davis E, George R, Gordon E, Lyons T, Wightman A, Ladin K. Ethical analysis examining the prioritisation of living donor transplantation in times of healthcare rationing. Journal Of Medical Ethics 2022 PMID: 34983855, DOI: 10.1136/medethics-2021-107574.
- Kulkarni SB, Joshi PM, Bandini M, Morey AF, Santucci RA, Fisch M, Djinovic R, Montorsi F, Barbagli G, Mundy T. Re: Sanad Saad, Nadir I. Osman, Christopher R. Chapple. Female Urethra: Is Ventral the True Dorsal? Eur Urol 2020;78:e218-9. European Urology 2022, 81: e14-e15. PMID: 34756627, DOI: 10.1016/j.eururo.2021.09.031.
- Thiessen C, Gannon J, Li S, Skrip L, Dobosz D, Gan G, Deng Y, Kennedy K, Gray D, Mussell A, Reese PP, Gordon EJ, Kulkarni S. Quantifying Risk Tolerance Among Potential Living Kidney Donors With the Donor-Specific Risk Questionnaire. American Journal Of Kidney Diseases : The Official Journal Of The National Kidney Foundation 2021, 78: 246-258. PMID: 33508397, DOI: 10.1053/j.ajkd.2020.11.028.
- Orandi BJ, Kulkarni S. Everything has a value, except human life. Transplant International : Official Journal Of The European Society For Organ Transplantation 2021, 34: 1571-1572. PMID: 34192376, PMCID: PMC8363555, DOI: 10.1111/tri.13966.
- Kulkarni S, Ladin K. Leveling-up versus leveling-down to address health disparities in transplantation. American Journal Of Transplantation : Official Journal Of The American Society Of Transplantation And The American Society Of Transplant Surgeons 2021, 21: 917-918. PMID: 33326686, PMCID: PMC7986107, DOI: 10.1111/ajt.16458.
- Merola J, Gan G, Stewart D, Noreen S, Mulligan D, Batra R, Haakinson D, Deng Y, Kulkarni S. Inactive status is an independent predictor of liver transplant waitlist mortality and is associated with a transplant centers median meld at transplant. PloS One 2021, 16: e0260000. PMID: 34793524, PMCID: PMC8601542, DOI: 10.1371/journal.pone.0260000.
- Ladin K, Kulkarni S. Reply to "Ethical principles governing organ transplantation apply to paired exchange programs". American Journal Of Transplantation : Official Journal Of The American Society Of Transplantation And The American Society Of Transplant Surgeons 2020, 20: 1758-1759. PMID: 32337792, DOI: 10.1111/ajt.15945.
- Kulkarni S, Wei G, Jiang W, Lopez LA, Parikh CR, Hall IE. Outcomes From Right Versus Left Deceased-Donor Kidney Transplants: A US National Cohort Study. American Journal Of Kidney Diseases : The Official Journal Of The National Kidney Foundation 2020, 75: 725-735. PMID: 31812448, PMCID: PMC7288694, DOI: 10.1053/j.ajkd.2019.08.018.
- Kulkarni S, Ladin K. Ethical principles governing organ transplantation apply to paired exchange programs. American Journal Of Transplantation : Official Journal Of The American Society Of Transplantation And The American Society Of Transplant Surgeons 2020, 20: 1223-1224. PMID: 32022980, PMCID: PMC7217160, DOI: 10.1111/ajt.15807.
- Cmunt K, Danovitch G, Delmonico F, Fynn-Thompson F, Glazier A, Grandas J, Gunderson S, Jendrisak M, Johnson HK, Kulkarni S, Lipkowitz G, Meyer K, Mulligan D, Nathan H, Mone T, Moritz M, O'Connor K, Payne W, Souter M, Wood RP. Deceased donors: Defining drug-related deaths. Clinical Transplantation 2020, 34: e13800. PMID: 32077534, DOI: 10.1111/ctr.13800.
- Schröppel B, Akalin E, Baweja M, Bloom RD, Florman S, Goldstein M, Haydel B, Hricik DE, Kulkarni S, Levine M, Mehrotra A, Patel A, Poggio ED, Ratner L, Shapiro R, Heeger PS. Peritransplant eculizumab does not prevent delayed graft function in deceased donor kidney transplant recipients: Results of two randomized controlled pilot trials. American Journal Of Transplantation : Official Journal Of The American Society Of Transplantation And The American Society Of Transplant Surgeons 2020, 20: 564-572. PMID: 31452319, DOI: 10.1111/ajt.15580.
- Cohen EA, McKimmy D, Cerilli A, Kulkarni S. A Pharmacist-Driven Intervention Designed to Improve Medication Accuracy in the Outpatient Kidney Transplant Setting. Drug, Healthcare And Patient Safety 2020, 12: 229-235. PMID: 33269008, PMCID: PMC7701366, DOI: 10.2147/DHPS.S264022.
- Kulkarni S, Ladin K, Haakinson D, Greene E, Li L, Deng Y. Association of Racial Disparities With Access to Kidney Transplant After the Implementation of the New Kidney Allocation System. JAMA Surgery 2019, 154: 618-625. PMID: 30942882, PMCID: PMC6583835, DOI: 10.1001/jamasurg.2019.0512.
- McCauley M, Mussell A, Goldberg D, Sawinski D, Molina RN, Tomlin R, Doshi SD, Abt P, Bloom R, Blumberg E, Kulkarni S, Esnaola G, Shults J, Thiessen C, Reese PP. Race, Risk, and Willingness of End-Stage Renal Disease Patients Without Hepatitis C Virus to Accept an HCV-Infected Kidney Transplant. Transplantation 2018, 102: e163-e170. PMID: 29346260, DOI: 10.1097/TP.0000000000002099.
- Dorflinger LM, Kulkarni S, Thiessen C, Klarman S, Fraenkel L. Assessing Living Donor Priorities Through Nominal Group Technique. Progress In Transplantation (Aliso Viejo, Calif.) 2018, 28: 29-35. PMID: 29243533, PMCID: PMC5735019, DOI: 10.1177/1526924817746682.
- Formica RN, Kulkarni S. Being Thoughtful about Desensitization. Clinical Journal Of The American Society Of Nephrology : CJASN 2017, 12: 1878-1880. PMID: 28974523, PMCID: PMC5672977, DOI: 10.2215/CJN.09000817.
- Thiessen C, Jaji Z, Joyce M, Zimbrean P, Reese P, Gordon EJ, Kulkarni S. Opting out: a single-centre pilot study assessing the reasons for and the psychosocial impact of withdrawing from living kidney donor evaluation. Journal Of Medical Ethics 2017, 43: 756-761. PMID: 28258071, DOI: 10.1136/medethics-2016-103512.
- Choe J, Merola J, Kulkarni S, Mulligan DC. Allograft transmission of hepatitis C during the window period: Weighing the new risks and costs in the era of donor shortage. Clinical Transplantation 2017, 31 PMID: 28643333, DOI: 10.1111/ctr.13022.
- Kulkarni S, Kirkiles-Smith NC, Deng YH, Formica RN, Moeckel G, Broecker V, Bow L, Tomlin R, Pober JS. Eculizumab Therapy for Chronic Antibody-Mediated Injury in Kidney Transplant Recipients: A Pilot Randomized Controlled Trial. American Journal Of Transplantation : Official Journal Of The American Society Of Transplantation And The American Society Of Transplant Surgeons 2017, 17: 682-691. PMID: 27501352, DOI: 10.1111/ajt.14001.
- Callender GG, Malinowski J, Javid M, Zhang Y, Huang H, Quinn CE, Carling T, Tomlin R, Smith JD, Kulkarni S. Parathyroidectomy prior to kidney transplant decreases graft failure. Surgery 2017, 161: 44-50. PMID: 27863776, DOI: 10.1016/j.surg.2016.10.003.
- Kulkarni S, Hall I, Formica R, Thiessen C, Stewart D, Gan G, Greene E, Deng Y. Transition probabilities between changing sensitization levels, waitlist activity status and competing-risk kidney transplant outcomes using multi-state modeling. PloS One 2017, 12: e0190277. PMID: 29287087, PMCID: PMC5747475, DOI: 10.1371/journal.pone.0190277.
- Kulkarni S, Thiessen C, Formica RN, Schilsky M, Mulligan D, D'Aquila R. The Long-Term Follow-up and Support for Living Organ Donors: A Center-Based Initiative Founded on Developing a Community of Living Donors. American Journal Of Transplantation : Official Journal Of The American Society Of Transplantation And The American Society Of Transplant Surgeons 2016, 16: 3385-3391. PMID: 27500361, DOI: 10.1111/ajt.14005.
- Thiessen C, Kulkarni S, Reese PP, Gordon EJ. A Call for Research on Individuals Who Opt Out of Living Kidney Donation: Challenges and Opportunities. Transplantation 2016, 100: 2527-2532. PMID: 27495760, DOI: 10.1097/TP.0000000000001408.
- Merola J, Yoo PS, Schaub J, Smith JD, Rodriguez-Davalos MI, Tichy E, Mulligan DC, Asch W, Formica R, Kashgarian M, Kulkarni S. Belatacept and Eculizumab for Treatment of Calcineurin Inhibitor-induced Thrombotic Microangiopathy After Kidney Transplantation: Case Report. Transplantation Proceedings 2016, 48: 3106-3108. PMID: 27932157, DOI: 10.1016/j.transproceed.2016.04.005.
- Tooley JE, Bohl DD, Kulkarni S, Rodriguez-Davalos MI, Mangi A, Mulligan DC, Yoo PS. Perioperative outcomes of coronary artery bypass graft in renal transplant recipients in the United States: results from the Nationwide Inpatient Sample. Clinical Transplantation 2016, 30: 1258-1263. PMID: 27440000, DOI: 10.1111/ctr.12816.
- Guerra CM, Formica RN, Kulkarni S, Asch WS, Tichy EM. Duration of prophylaxis against fungal infection in kidney transplant recipients. Progress In Transplantation (Aliso Viejo, Calif.) 2015, 25: 311-5. PMID: 26645924, DOI: 10.7182/pit2015929.
- Thiessen C, Gordon EJ, Reese PP, Kulkarni S. Development of a Donor-Centered Approach to Risk Assessment: Rebalancing Nonmaleficence and Autonomy. American Journal Of Transplantation : Official Journal Of The American Society Of Transplantation And The American Society Of Transplant Surgeons 2015, 15: 2314-23. PMID: 25868787, DOI: 10.1111/ajt.13272.
- Thiessen C, Kim YA, Formica R, Bia M, Kulkarni S. Opting out: confidentiality and availability of an 'alibi' for potential living kidney donors in the USA. Journal Of Medical Ethics 2015, 41: 506-10. PMID: 25368413, DOI: 10.1136/medethics-2014-102184.
- Vilarinho S, Choi M, Jain D, Malhotra A, Kulkarni S, Pashankar D, Phatak U, Patel M, Bale A, Mane S, Lifton RP, Mistry PK. Individual exome analysis in diagnosis and management of paediatric liver failure of indeterminate aetiology. Journal Of Hepatology 2014, 61: 1056-63. PMID: 25016221, PMCID: PMC4203706, DOI: 10.1016/j.jhep.2014.06.038.
- Thiessen C, Kim YA, Yoo PS, Rodriguez-Davalos M, Mulligan D, Kulkarni S. Written informed consent for living liver donor evaluation: compliance with Centers for Medicare and Medicaid Services and Organ Procurement and Transplantation Network Guidelines and alibi offers. Liver Transplantation : Official Publication Of The American Association For The Study Of Liver Diseases And The International Liver Transplantation Society 2014, 20: 416-24. PMID: 24415564, DOI: 10.1002/lt.23822.
- Rodriguez-Davalos MI, Arvelakis A, Umman V, Tanjavur V, Yoo PS, Kulkarni S, Luczycki SM, Schilsky M, Emre S. Segmental grafts in adult and pediatric liver transplantation: improving outcomes by minimizing vascular complications. JAMA Surgery 2014, 149: 63-70. PMID: 24284803, DOI: 10.1001/jamasurg.2013.3384.
- Jane-Wit D, Manes TD, Yi T, Qin L, Clark P, Kirkiles-Smith NC, Abrahimi P, Devalliere J, Moeckel G, Kulkarni S, Tellides G, Pober JS. Alloantibody and complement promote T cell-mediated cardiac allograft vasculopathy through noncanonical nuclear factor-κB signaling in endothelial cells. Circulation 2013, 128: 2504-16. PMID: 24045046, PMCID: PMC3885874, DOI: 10.1161/CIRCULATIONAHA.113.002972.
- Davarpanah AH, Pahade JK, Cornfeld D, Ghita M, Kulkarni S, Israel GM. CT angiography in potential living kidney donors: 80 kVp versus 120 kVp. AJR. American Journal Of Roentgenology 2013, 201: W753-60. PMID: 24147505, DOI: 10.2214/AJR.12.10439.
- Thiessen C, Kim YA, Formica R, Bia M, Kulkarni S. Written informed consent for living kidney donors: practices and compliance with CMS and OPTN requirements. American Journal Of Transplantation : Official Journal Of The American Society Of Transplantation And The American Society Of Transplant Surgeons 2013, 13: 2713-21. PMID: 24020884, DOI: 10.1111/ajt.12406.
- Gandelman JA, Yoo PS, Kulkarni S. Retrocaval renal artery bifurcation is not a contraindication to laparoscopic right donor nephrectomy. Journal Of The American College Of Surgeons 2013, 217: 406-11. PMID: 23791562, DOI: 10.1016/j.jamcollsurg.2013.03.026.
- Heavner MS, Tichy EM, Yazdi M, Formica RN, Kulkarni S, Emre S. Clinical outcomes associated with conversion from brand-name to generic tacrolimus in hospitalized kidney transplant recipients. American Journal Of Health-system Pharmacy : AJHP : Official Journal Of The American Society Of Health-System Pharmacists 2013, 70: 1507-12. PMID: 23943182, DOI: 10.2146/ajhp120783.
- Yoo PS, Enestvedt CK, Kulkarni S. Anatomic considerations in the surgical resection of hepatocellular carcinoma. Journal Of Clinical Gastroenterology 2013, 47 Suppl: S11-5. PMID: 23632343, DOI: 10.1097/MCG.0b013e318280ce5f.
- Wang C, Yi T, Qin L, Maldonado RA, von Andrian UH, Kulkarni S, Tellides G, Pober JS. Rapamycin-treated human endothelial cells preferentially activate allogeneic regulatory T cells. The Journal Of Clinical Investigation 2013, 123: 1677-93. PMID: 23478407, PMCID: PMC3613923, DOI: 10.1172/JCI66204.
- Mittal R, Kalra P, Dharmalingam M, Verma RG, Kulkarni S, Shetty P. Lymphocytic hypophysitis masquerading as pituitary adenoma. Indian Journal Of Endocrinology And Metabolism 2012, 16: S304-6. PMID: 23565408, PMCID: PMC3603056, DOI: 10.4103/2230-8210.104069.
- Formica RN, Barrantes F, Asch WS, Bia MJ, Coca S, Kalyesubula R, McCloskey B, Leary T, Arvelakis A, Kulkarni S. A one-day centralized work-up for kidney transplant recipient candidates: a quality improvement report. American Journal Of Kidney Diseases : The Official Journal Of The National Kidney Foundation 2012, 60: 288-94. PMID: 22571868, DOI: 10.1053/j.ajkd.2012.04.008.
- Guo X, Schmitz JC, Kenney BC, Uchio EM, Kulkarni S, Cha CH. Intermedin is overexpressed in hepatocellular carcinoma and regulates cell proliferation and survival. Cancer Science 2012, 103: 1474-80. PMID: 22625651, PMCID: PMC7659195, DOI: 10.1111/j.1349-7006.2012.02341.x.
- Yi T, Fogal B, Hao Z, Tobiasova Z, Wang C, Rao DA, Al-Lamki RS, Kirkiles-Smith NC, Kulkarni S, Bradley JR, Bothwell AL, Sessa WC, Tellides G, Pober JS. Reperfusion injury intensifies the adaptive human T cell alloresponse in a human-mouse chimeric artery model. Arteriosclerosis, Thrombosis, And Vascular Biology 2012, 32: 353-60. PMID: 22053072, PMCID: PMC3262100, DOI: 10.1161/ATVBAHA.111.239285.
- Fogal B, Yi T, Wang C, Rao DA, Lebastchi A, Kulkarni S, Tellides G, Pober JS. Neutralizing IL-6 reduces human arterial allograft rejection by allowing emergence of CD161+ CD4+ regulatory T cells. Journal Of Immunology (Baltimore, Md. : 1950) 2011, 187: 6268-80. PMID: 22084439, PMCID: PMC3237826, DOI: 10.4049/jimmunol.1003774.
- Singh M, Singh G, Pandey A, Cha CH, Kulkarni S. Laparoscopic repair of iatrogenic diaphragmatic hernia following radiofrequency ablation for hepatocellular carcinoma. Hepatology Research : The Official Journal Of The Japan Society Of Hepatology 2011, 41: 1132-6. PMID: 22032681, DOI: 10.1111/j.1872-034X.2011.00865.x.
- Solomon DA, Rabidou N, Kulkarni S, Formica R, Fraenkel L. Accepting a donor kidney: an evaluation of patients' and transplant surgeons' priorities. Clinical Transplantation 2011, 25: 786-93. PMID: 20964716, PMCID: PMC4846340, DOI: 10.1111/j.1399-0012.2010.01342.x.
- Tobiasova Z, Zhang L, Yi T, Qin L, Manes TD, Kulkarni S, Lorber MI, Rodriguez FC, Choi JM, Tellides G, Pober JS, Kawikova I, Bothwell AL. Peroxisome proliferator-activated receptor-γ agonists prevent in vivo remodeling of human artery induced by alloreactive T cells. Circulation 2011, 124: 196-205. PMID: 21690493, PMCID: PMC3347886, DOI: 10.1161/CIRCULATIONAHA.110.015396.
- Kulkarni S, Taddei TH. When should a hepatitis C-positive ESRD patient receive a renal transplant? Seminars In Dialysis 2011, 24: 438-9. PMID: 21801216, DOI: 10.1111/j.1525-139X.2011.00898.x.
- Cimsit B, Schilsky M, Moini M, Cartiera K, Arvelakis A, Kulkarni S, Formica R, Caldwell C, Taddei T, Asch W, Emre S. Combined liver kidney transplantation: critical analysis of a single-center experience. Transplantation Proceedings 2011, 43: 901-4. PMID: 21486624, DOI: 10.1016/j.transproceed.2011.02.033.
- Cimsit B, Assis D, Caldwell C, Arvelakis A, Taddei T, Kulkarni S, Schilsky M, Emre S. Successful treatment of fibrosing cholestatic hepatitis after liver transplantation. Transplantation Proceedings 2011, 43: 905-8. PMID: 21486625, DOI: 10.1016/j.transproceed.2011.02.034.
- Renal transplantation for nephrogenic systemic fibrosis: a case report and review of the literature.Cuffy MC, Singh M, Formica R, Simmons E, Abu Alfa AK, Carlson K, Girardi M, Cowper SE, Kulkarni S. Renal transplantation for nephrogenic systemic fibrosis: a case report and review of the literature. Nephrology, Dialysis, Transplantation : Official Publication Of The European Dialysis And Transplant Association - European Renal Association 2011, 26: 1099-101. PMID: 21079195, DOI: 10.1093/ndt/gfq693.
- Kulkarni S, Emre S, Arvelakis A, Asch W, Bia M, Formica R, Israel G. Multidetector CT angiography in living donor renal transplantation: accuracy and discrepancies in right venous anatomy. Clinical Transplantation 2011, 25: 77-82. PMID: 20070320, DOI: 10.1111/j.1399-0012.2009.01193.x.
- Bia M, Adey DB, Bloom RD, Chan L, Kulkarni S, Tomlanovich S. KDOQI US commentary on the 2009 KDIGO clinical practice guideline for the care of kidney transplant recipients. American Journal Of Kidney Diseases : The Official Journal Of The National Kidney Foundation 2010, 56: 189-218. PMID: 20598411, DOI: 10.1053/j.ajkd.2010.04.010.
- Caldwell C, Werdiger N, Jakab S, Schilsky M, Arvelakis A, Kulkarni S, Emre S. Use of model for end-stage liver disease exception points for early liver transplantation and successful reversal of hepatic myelopathy with a review of the literature. Liver Transplantation : Official Publication Of The American Association For The Study Of Liver Diseases And The International Liver Transplantation Society 2010, 16: 818-26. PMID: 20583082, DOI: 10.1002/lt.22077.
- Tichy EM, Medwid AJ, Mills EA, Formica RN, Kulkarni S. Significant sirolimus and dronedarone interaction in a kidney transplant recipient. The Annals Of Pharmacotherapy 2010, 44: 1338-41. PMID: 20484171, DOI: 10.1345/aph.1P114.
- Formica RN, Asch WS, Wagner KR, Kulkarni S. Kidney transplantation and HIV: does recipient privacy outweigh the donor's right to information? Clinical Journal Of The American Society Of Nephrology : CJASN 2010, 5: 924-8. PMID: 20203162, PMCID: PMC2863980, DOI: 10.2215/CJN.06820909.
- Parekh AM, Gordon EJ, Garg AX, Waterman AD, Kulkarni S, Parikh CR. Living kidney donor informed consent practices vary between US and non-US centers. Nephrology, Dialysis, Transplantation : Official Publication Of The European Dialysis And Transplant Association - European Renal Association 2008, 23: 3316-24. PMID: 18599559, PMCID: PMC2720811, DOI: 10.1093/ndt/gfn295.
- Friedman AL, Geoghegan SR, Sowers NM, Kulkarni S, Formica RN. Medication errors in the outpatient setting: classification and root cause analysis. Archives Of Surgery (Chicago, Ill. : 1960) 2007, 142: 278-83; discussion 284. PMID: 17372053, DOI: 10.1001/archsurg.142.3.278.
- Kulkarni S, Cronin DC. Ethics in liver transplantation. Seminars In Liver Disease 2006, 26: 234-8. PMID: 16850372, DOI: 10.1055/s-2006-947299.
- Kulkarni S, Cronin DC. Ethical tensions in solid organ transplantation: the price of success. World Journal Of Gastroenterology : WJG 2006, 12: 3259-64. PMID: 16718849, PMCID: PMC4087972, DOI: 10.3748/wjg.v12.i20.3259.
- Kulkarni S, Malagò M, Cronin DC. Living donor liver transplantation for pediatric and adult recipients. Nature Clinical Practice. Gastroenterology & Hepatology 2006, 3: 149-57. PMID: 16511549, DOI: 10.1038/ncpgasthep0437.
- Schaffer RL, Kulkarni S, Harper A, Millis JM, Cronin DC. The sickest first? Disparities with model for end-stage liver disease-based organ allocation: one region's experience. Liver Transplantation : Official Publication Of The American Association For The Study Of Liver Diseases And The International Liver Transplantation Society 2003, 9: 1211-5. PMID: 14586883, DOI: 10.1053/jlts.2003.50192.
- Kulkarni S, Naureckas E, Cronin DC. Solid-organ transplant recipients treated with drotrecogin alfa (activated) for severe sepsis. Transplantation 2003, 75: 899-901. PMID: 12660522, DOI: 10.1097/01.TP.0000054842.34916.E8.
- Kulkarni S, Holman PO, Kopelan A, van Seventer GA, van Seventer JM, Kranz DM, Woodle ES. Programmed cell death signaling via cell-surface expression of a single-chain antibody transgene. Transplantation 2000, 69: 1209-17. PMID: 10762228, DOI: 10.1097/00007890-200003270-00028.
- O'Herrin SM, Kulkarni S, Kenealy WR, Fechner JH, Sollinger H, Schneck JP, Burlingham WJ. Expression of human recombinant beta 2-microglobulin by Aspergillus nidulans and its activity. Human Immunology 1996, 51: 63-72. PMID: 8960907.
- Yale-New Haven Transplantation CenterYale Physicians Building800 Howard Avenue, Ste 3rd floorNew Haven, CT 06519
- Yale Transplant & ImmunologyFarnam Memorial Building310 Cedar StreetNew Haven, CT 06510
Biography
Sanjay Kulkarni, MD, is a multi-organ transplant surgeon and medical director of the Center for Living Organ Donors at Yale New Haven Hospital. In this role Dr. Kulkarni helped pioneer a unique initiative that is first in the United States of its kind. The Center for Living Organ Donors creates supportive communities of living donors and provides them with free, lifelong local medical monitoring for any health issues that may arise related to their organ donation.
“I think I have the best job in the world,” says Dr. Kulkarni. “I deal with living organ donors every single day—individuals who constantly remind you what a major difference one person’s generosity can make in another person’s life, and for the benefit of society.”
Dr. Kulkarni performs all living donor evaluations and 95 percent of kidney donor surgeries for Yale Medicine. He has played a role in such high-profile surgeries as Connecticut’s first eight-patient kidney transplant exchange in 2015. In this complex match-up, four women underwent surgery to give four men the kidneys they needed.
Dr. Kulkarni is also the surgical director of the Yale Medicine Kidney and Pancreas Transplant Program, a destination center for patients who need these transplants, and the largest program for both kidney transplantation and living-donor kidney transplantation in New England. Dr. Kulkarni and his colleagues in the program specialize in minimally invasive surgical approaches, which typically reduce pain and hasten recoveries.
An associate professor of transplant surgery and of nephrology at Yale School of Medicine, Dr. Kulkarni is also the scientific director of the Yale Transplant Research Unit, which pursues new therapies for transplant patients. His personal research explores the ethics surrounding care of living donors, understanding the reasons why some people come forward to be considered as a donor then opt out, and the use of social networking to foster donor communities.
Titles
- Professor of Surgery (Transplant)
- Physician Executive Director, Clinical Continuity & Integration, Yale-New Haven Hospital
- Surgical Director, Kidney Transplant Program
- Medical Director, New England Donor Services
- Medical Director, Center for Living Organ Donors
Education & Training
- MHCMHarvard University, School of Public Health (2018)
- Global Clinical Scholars Training Program (GCSRT)Harvard Medical School (2015)
- FellowUniversity of Chicago Hospitals, Chicago, IL (2004)
- FellowUniversity Hospital Essen, Germany (2004)
- Clinical Research Training Program (CRTP)University of Chicago, Pritzker School of Medicine (2004)
- Chief ResidentUniversity of Chicago Hospitals, Chicago, IL (2002)
- ResidentUniversity of Chicago Hospitals, Chicago, IL (2001)
- Research FellowUniversity of Chicago, Chicago, IL (1999)
- MDMedical College Wisconsin (1995)
- BSUniversity of Wisconsin (1990)
- Research FellowUniversity of Wisconsin-Madison, Madison, WI (1990)
Languages Spoken
- English
- Deutsch (German)
Additional Information
- AB of Surgery, Surgery, General (2003, recertified: 2012)
- UNOS (2020 - Present): Ethics Committee
- American Journal of Transplantation (2019 - Present): Associate Editor
- AASLD (2013 - 2015): AASLD, Liver & Intestive Committee
- UNOS (2013 - 2015): Region representative, UNOS Living Donor Committee
- Sun Z, Zhang Z, Banu K, Azzi YA, Reghuvaran A, Fredericks S, Planoutene M, Hartzell S, Kim Y, Pell J, Tietjen G, Asch W, Kulkarni S, Formica R, Rana M, Maltzman JS, Zhang W, Akalin E, Heeger PS, Cravedi P, Menon MC. Blood Transcriptomes of SARS-CoV-2-Infected Kidney Transplant Recipients Associated with Immune Insufficiency Proportionate to Severity. Journal Of The American Society Of Nephrology : JASN 2022 PMID: 36041788, DOI: 10.1681/ASN.2022010125.
- Kulkarni S, Glazier A, Lipkowitz G, Fynn-Tompson F, Woolley AE, Delmonico FL. A Collaborative Stewardship of OPOs and Transplant Centers to Maintain Equitable Allocation when Facilitating Ex Vivo Organ Preservation. American Journal Of Transplantation : Official Journal Of The American Society Of Transplantation And The American Society Of Transplant Surgeons 2022 PMID: 35704287, DOI: 10.1111/ajt.17120.
- Azar MM, Cohen E, Ma L, Cissé OH, Gan G, Deng Y, Belfield K, Asch W, Grant M, Gleeson S, Koff A, Gaston DC, Topal J, Curran S, Kulkarni S, Kovacs JA, Malinis M. Genetic and Epidemiologic Analyses of an Outbreak of Pneumocystis jirovecii Pneumonia Among Kidney Transplant Recipients in the United States. Clinical Infectious Diseases : An Official Publication Of The Infectious Diseases Society Of America 2022, 74: 639-647. PMID: 34017984, PMCID: PMC9012955, DOI: 10.1093/cid/ciab474.
- Kulkarni S, Flescher A, Ahmad M, Bayliss G, Bearl D, Biondi L, Davis E, George R, Gordon E, Lyons T, Wightman A, Ladin K. Ethical analysis examining the prioritisation of living donor transplantation in times of healthcare rationing. Journal Of Medical Ethics 2022 PMID: 34983855, DOI: 10.1136/medethics-2021-107574.
- Kulkarni SB, Joshi PM, Bandini M, Morey AF, Santucci RA, Fisch M, Djinovic R, Montorsi F, Barbagli G, Mundy T. Re: Sanad Saad, Nadir I. Osman, Christopher R. Chapple. Female Urethra: Is Ventral the True Dorsal? Eur Urol 2020;78:e218-9. European Urology 2022, 81: e14-e15. PMID: 34756627, DOI: 10.1016/j.eururo.2021.09.031.
- Thiessen C, Gannon J, Li S, Skrip L, Dobosz D, Gan G, Deng Y, Kennedy K, Gray D, Mussell A, Reese PP, Gordon EJ, Kulkarni S. Quantifying Risk Tolerance Among Potential Living Kidney Donors With the Donor-Specific Risk Questionnaire. American Journal Of Kidney Diseases : The Official Journal Of The National Kidney Foundation 2021, 78: 246-258. PMID: 33508397, DOI: 10.1053/j.ajkd.2020.11.028.
- Orandi BJ, Kulkarni S. Everything has a value, except human life. Transplant International : Official Journal Of The European Society For Organ Transplantation 2021, 34: 1571-1572. PMID: 34192376, PMCID: PMC8363555, DOI: 10.1111/tri.13966.
- Kulkarni S, Ladin K. Leveling-up versus leveling-down to address health disparities in transplantation. American Journal Of Transplantation : Official Journal Of The American Society Of Transplantation And The American Society Of Transplant Surgeons 2021, 21: 917-918. PMID: 33326686, PMCID: PMC7986107, DOI: 10.1111/ajt.16458.
- Merola J, Gan G, Stewart D, Noreen S, Mulligan D, Batra R, Haakinson D, Deng Y, Kulkarni S. Inactive status is an independent predictor of liver transplant waitlist mortality and is associated with a transplant centers median meld at transplant. PloS One 2021, 16: e0260000. PMID: 34793524, PMCID: PMC8601542, DOI: 10.1371/journal.pone.0260000.
- Ladin K, Kulkarni S. Reply to "Ethical principles governing organ transplantation apply to paired exchange programs". American Journal Of Transplantation : Official Journal Of The American Society Of Transplantation And The American Society Of Transplant Surgeons 2020, 20: 1758-1759. PMID: 32337792, DOI: 10.1111/ajt.15945.
- Kulkarni S, Wei G, Jiang W, Lopez LA, Parikh CR, Hall IE. Outcomes From Right Versus Left Deceased-Donor Kidney Transplants: A US National Cohort Study. American Journal Of Kidney Diseases : The Official Journal Of The National Kidney Foundation 2020, 75: 725-735. PMID: 31812448, PMCID: PMC7288694, DOI: 10.1053/j.ajkd.2019.08.018.
- Kulkarni S, Ladin K. Ethical principles governing organ transplantation apply to paired exchange programs. American Journal Of Transplantation : Official Journal Of The American Society Of Transplantation And The American Society Of Transplant Surgeons 2020, 20: 1223-1224. PMID: 32022980, PMCID: PMC7217160, DOI: 10.1111/ajt.15807.
- Cmunt K, Danovitch G, Delmonico F, Fynn-Thompson F, Glazier A, Grandas J, Gunderson S, Jendrisak M, Johnson HK, Kulkarni S, Lipkowitz G, Meyer K, Mulligan D, Nathan H, Mone T, Moritz M, O'Connor K, Payne W, Souter M, Wood RP. Deceased donors: Defining drug-related deaths. Clinical Transplantation 2020, 34: e13800. PMID: 32077534, DOI: 10.1111/ctr.13800.
- Schröppel B, Akalin E, Baweja M, Bloom RD, Florman S, Goldstein M, Haydel B, Hricik DE, Kulkarni S, Levine M, Mehrotra A, Patel A, Poggio ED, Ratner L, Shapiro R, Heeger PS. Peritransplant eculizumab does not prevent delayed graft function in deceased donor kidney transplant recipients: Results of two randomized controlled pilot trials. American Journal Of Transplantation : Official Journal Of The American Society Of Transplantation And The American Society Of Transplant Surgeons 2020, 20: 564-572. PMID: 31452319, DOI: 10.1111/ajt.15580.
- Cohen EA, McKimmy D, Cerilli A, Kulkarni S. A Pharmacist-Driven Intervention Designed to Improve Medication Accuracy in the Outpatient Kidney Transplant Setting. Drug, Healthcare And Patient Safety 2020, 12: 229-235. PMID: 33269008, PMCID: PMC7701366, DOI: 10.2147/DHPS.S264022.
- Kulkarni S, Ladin K, Haakinson D, Greene E, Li L, Deng Y. Association of Racial Disparities With Access to Kidney Transplant After the Implementation of the New Kidney Allocation System. JAMA Surgery 2019, 154: 618-625. PMID: 30942882, PMCID: PMC6583835, DOI: 10.1001/jamasurg.2019.0512.
- McCauley M, Mussell A, Goldberg D, Sawinski D, Molina RN, Tomlin R, Doshi SD, Abt P, Bloom R, Blumberg E, Kulkarni S, Esnaola G, Shults J, Thiessen C, Reese PP. Race, Risk, and Willingness of End-Stage Renal Disease Patients Without Hepatitis C Virus to Accept an HCV-Infected Kidney Transplant. Transplantation 2018, 102: e163-e170. PMID: 29346260, DOI: 10.1097/TP.0000000000002099.
- Dorflinger LM, Kulkarni S, Thiessen C, Klarman S, Fraenkel L. Assessing Living Donor Priorities Through Nominal Group Technique. Progress In Transplantation (Aliso Viejo, Calif.) 2018, 28: 29-35. PMID: 29243533, PMCID: PMC5735019, DOI: 10.1177/1526924817746682.
- Formica RN, Kulkarni S. Being Thoughtful about Desensitization. Clinical Journal Of The American Society Of Nephrology : CJASN 2017, 12: 1878-1880. PMID: 28974523, PMCID: PMC5672977, DOI: 10.2215/CJN.09000817.
- Thiessen C, Jaji Z, Joyce M, Zimbrean P, Reese P, Gordon EJ, Kulkarni S. Opting out: a single-centre pilot study assessing the reasons for and the psychosocial impact of withdrawing from living kidney donor evaluation. Journal Of Medical Ethics 2017, 43: 756-761. PMID: 28258071, DOI: 10.1136/medethics-2016-103512.
- Choe J, Merola J, Kulkarni S, Mulligan DC. Allograft transmission of hepatitis C during the window period: Weighing the new risks and costs in the era of donor shortage. Clinical Transplantation 2017, 31 PMID: 28643333, DOI: 10.1111/ctr.13022.
- Kulkarni S, Kirkiles-Smith NC, Deng YH, Formica RN, Moeckel G, Broecker V, Bow L, Tomlin R, Pober JS. Eculizumab Therapy for Chronic Antibody-Mediated Injury in Kidney Transplant Recipients: A Pilot Randomized Controlled Trial. American Journal Of Transplantation : Official Journal Of The American Society Of Transplantation And The American Society Of Transplant Surgeons 2017, 17: 682-691. PMID: 27501352, DOI: 10.1111/ajt.14001.
- Callender GG, Malinowski J, Javid M, Zhang Y, Huang H, Quinn CE, Carling T, Tomlin R, Smith JD, Kulkarni S. Parathyroidectomy prior to kidney transplant decreases graft failure. Surgery 2017, 161: 44-50. PMID: 27863776, DOI: 10.1016/j.surg.2016.10.003.
- Kulkarni S, Hall I, Formica R, Thiessen C, Stewart D, Gan G, Greene E, Deng Y. Transition probabilities between changing sensitization levels, waitlist activity status and competing-risk kidney transplant outcomes using multi-state modeling. PloS One 2017, 12: e0190277. PMID: 29287087, PMCID: PMC5747475, DOI: 10.1371/journal.pone.0190277.
- Kulkarni S, Thiessen C, Formica RN, Schilsky M, Mulligan D, D'Aquila R. The Long-Term Follow-up and Support for Living Organ Donors: A Center-Based Initiative Founded on Developing a Community of Living Donors. American Journal Of Transplantation : Official Journal Of The American Society Of Transplantation And The American Society Of Transplant Surgeons 2016, 16: 3385-3391. PMID: 27500361, DOI: 10.1111/ajt.14005.
- Thiessen C, Kulkarni S, Reese PP, Gordon EJ. A Call for Research on Individuals Who Opt Out of Living Kidney Donation: Challenges and Opportunities. Transplantation 2016, 100: 2527-2532. PMID: 27495760, DOI: 10.1097/TP.0000000000001408.
- Merola J, Yoo PS, Schaub J, Smith JD, Rodriguez-Davalos MI, Tichy E, Mulligan DC, Asch W, Formica R, Kashgarian M, Kulkarni S. Belatacept and Eculizumab for Treatment of Calcineurin Inhibitor-induced Thrombotic Microangiopathy After Kidney Transplantation: Case Report. Transplantation Proceedings 2016, 48: 3106-3108. PMID: 27932157, DOI: 10.1016/j.transproceed.2016.04.005.
- Tooley JE, Bohl DD, Kulkarni S, Rodriguez-Davalos MI, Mangi A, Mulligan DC, Yoo PS. Perioperative outcomes of coronary artery bypass graft in renal transplant recipients in the United States: results from the Nationwide Inpatient Sample. Clinical Transplantation 2016, 30: 1258-1263. PMID: 27440000, DOI: 10.1111/ctr.12816.
- Guerra CM, Formica RN, Kulkarni S, Asch WS, Tichy EM. Duration of prophylaxis against fungal infection in kidney transplant recipients. Progress In Transplantation (Aliso Viejo, Calif.) 2015, 25: 311-5. PMID: 26645924, DOI: 10.7182/pit2015929.
- Thiessen C, Gordon EJ, Reese PP, Kulkarni S. Development of a Donor-Centered Approach to Risk Assessment: Rebalancing Nonmaleficence and Autonomy. American Journal Of Transplantation : Official Journal Of The American Society Of Transplantation And The American Society Of Transplant Surgeons 2015, 15: 2314-23. PMID: 25868787, DOI: 10.1111/ajt.13272.
- Thiessen C, Kim YA, Formica R, Bia M, Kulkarni S. Opting out: confidentiality and availability of an 'alibi' for potential living kidney donors in the USA. Journal Of Medical Ethics 2015, 41: 506-10. PMID: 25368413, DOI: 10.1136/medethics-2014-102184.
- Vilarinho S, Choi M, Jain D, Malhotra A, Kulkarni S, Pashankar D, Phatak U, Patel M, Bale A, Mane S, Lifton RP, Mistry PK. Individual exome analysis in diagnosis and management of paediatric liver failure of indeterminate aetiology. Journal Of Hepatology 2014, 61: 1056-63. PMID: 25016221, PMCID: PMC4203706, DOI: 10.1016/j.jhep.2014.06.038.
- Thiessen C, Kim YA, Yoo PS, Rodriguez-Davalos M, Mulligan D, Kulkarni S. Written informed consent for living liver donor evaluation: compliance with Centers for Medicare and Medicaid Services and Organ Procurement and Transplantation Network Guidelines and alibi offers. Liver Transplantation : Official Publication Of The American Association For The Study Of Liver Diseases And The International Liver Transplantation Society 2014, 20: 416-24. PMID: 24415564, DOI: 10.1002/lt.23822.
- Rodriguez-Davalos MI, Arvelakis A, Umman V, Tanjavur V, Yoo PS, Kulkarni S, Luczycki SM, Schilsky M, Emre S. Segmental grafts in adult and pediatric liver transplantation: improving outcomes by minimizing vascular complications. JAMA Surgery 2014, 149: 63-70. PMID: 24284803, DOI: 10.1001/jamasurg.2013.3384.
- Jane-Wit D, Manes TD, Yi T, Qin L, Clark P, Kirkiles-Smith NC, Abrahimi P, Devalliere J, Moeckel G, Kulkarni S, Tellides G, Pober JS. Alloantibody and complement promote T cell-mediated cardiac allograft vasculopathy through noncanonical nuclear factor-κB signaling in endothelial cells. Circulation 2013, 128: 2504-16. PMID: 24045046, PMCID: PMC3885874, DOI: 10.1161/CIRCULATIONAHA.113.002972.
- Davarpanah AH, Pahade JK, Cornfeld D, Ghita M, Kulkarni S, Israel GM. CT angiography in potential living kidney donors: 80 kVp versus 120 kVp. AJR. American Journal Of Roentgenology 2013, 201: W753-60. PMID: 24147505, DOI: 10.2214/AJR.12.10439.
- Thiessen C, Kim YA, Formica R, Bia M, Kulkarni S. Written informed consent for living kidney donors: practices and compliance with CMS and OPTN requirements. American Journal Of Transplantation : Official Journal Of The American Society Of Transplantation And The American Society Of Transplant Surgeons 2013, 13: 2713-21. PMID: 24020884, DOI: 10.1111/ajt.12406.
- Gandelman JA, Yoo PS, Kulkarni S. Retrocaval renal artery bifurcation is not a contraindication to laparoscopic right donor nephrectomy. Journal Of The American College Of Surgeons 2013, 217: 406-11. PMID: 23791562, DOI: 10.1016/j.jamcollsurg.2013.03.026.
- Heavner MS, Tichy EM, Yazdi M, Formica RN, Kulkarni S, Emre S. Clinical outcomes associated with conversion from brand-name to generic tacrolimus in hospitalized kidney transplant recipients. American Journal Of Health-system Pharmacy : AJHP : Official Journal Of The American Society Of Health-System Pharmacists 2013, 70: 1507-12. PMID: 23943182, DOI: 10.2146/ajhp120783.
- Yoo PS, Enestvedt CK, Kulkarni S. Anatomic considerations in the surgical resection of hepatocellular carcinoma. Journal Of Clinical Gastroenterology 2013, 47 Suppl: S11-5. PMID: 23632343, DOI: 10.1097/MCG.0b013e318280ce5f.
- Wang C, Yi T, Qin L, Maldonado RA, von Andrian UH, Kulkarni S, Tellides G, Pober JS. Rapamycin-treated human endothelial cells preferentially activate allogeneic regulatory T cells. The Journal Of Clinical Investigation 2013, 123: 1677-93. PMID: 23478407, PMCID: PMC3613923, DOI: 10.1172/JCI66204.
- Mittal R, Kalra P, Dharmalingam M, Verma RG, Kulkarni S, Shetty P. Lymphocytic hypophysitis masquerading as pituitary adenoma. Indian Journal Of Endocrinology And Metabolism 2012, 16: S304-6. PMID: 23565408, PMCID: PMC3603056, DOI: 10.4103/2230-8210.104069.
- Formica RN, Barrantes F, Asch WS, Bia MJ, Coca S, Kalyesubula R, McCloskey B, Leary T, Arvelakis A, Kulkarni S. A one-day centralized work-up for kidney transplant recipient candidates: a quality improvement report. American Journal Of Kidney Diseases : The Official Journal Of The National Kidney Foundation 2012, 60: 288-94. PMID: 22571868, DOI: 10.1053/j.ajkd.2012.04.008.
- Guo X, Schmitz JC, Kenney BC, Uchio EM, Kulkarni S, Cha CH. Intermedin is overexpressed in hepatocellular carcinoma and regulates cell proliferation and survival. Cancer Science 2012, 103: 1474-80. PMID: 22625651, PMCID: PMC7659195, DOI: 10.1111/j.1349-7006.2012.02341.x.
- Yi T, Fogal B, Hao Z, Tobiasova Z, Wang C, Rao DA, Al-Lamki RS, Kirkiles-Smith NC, Kulkarni S, Bradley JR, Bothwell AL, Sessa WC, Tellides G, Pober JS. Reperfusion injury intensifies the adaptive human T cell alloresponse in a human-mouse chimeric artery model. Arteriosclerosis, Thrombosis, And Vascular Biology 2012, 32: 353-60. PMID: 22053072, PMCID: PMC3262100, DOI: 10.1161/ATVBAHA.111.239285.
- Fogal B, Yi T, Wang C, Rao DA, Lebastchi A, Kulkarni S, Tellides G, Pober JS. Neutralizing IL-6 reduces human arterial allograft rejection by allowing emergence of CD161+ CD4+ regulatory T cells. Journal Of Immunology (Baltimore, Md. : 1950) 2011, 187: 6268-80. PMID: 22084439, PMCID: PMC3237826, DOI: 10.4049/jimmunol.1003774.
- Singh M, Singh G, Pandey A, Cha CH, Kulkarni S. Laparoscopic repair of iatrogenic diaphragmatic hernia following radiofrequency ablation for hepatocellular carcinoma. Hepatology Research : The Official Journal Of The Japan Society Of Hepatology 2011, 41: 1132-6. PMID: 22032681, DOI: 10.1111/j.1872-034X.2011.00865.x.
- Solomon DA, Rabidou N, Kulkarni S, Formica R, Fraenkel L. Accepting a donor kidney: an evaluation of patients' and transplant surgeons' priorities. Clinical Transplantation 2011, 25: 786-93. PMID: 20964716, PMCID: PMC4846340, DOI: 10.1111/j.1399-0012.2010.01342.x.
- Tobiasova Z, Zhang L, Yi T, Qin L, Manes TD, Kulkarni S, Lorber MI, Rodriguez FC, Choi JM, Tellides G, Pober JS, Kawikova I, Bothwell AL. Peroxisome proliferator-activated receptor-γ agonists prevent in vivo remodeling of human artery induced by alloreactive T cells. Circulation 2011, 124: 196-205. PMID: 21690493, PMCID: PMC3347886, DOI: 10.1161/CIRCULATIONAHA.110.015396.
- Kulkarni S, Taddei TH. When should a hepatitis C-positive ESRD patient receive a renal transplant? Seminars In Dialysis 2011, 24: 438-9. PMID: 21801216, DOI: 10.1111/j.1525-139X.2011.00898.x.
- Cimsit B, Schilsky M, Moini M, Cartiera K, Arvelakis A, Kulkarni S, Formica R, Caldwell C, Taddei T, Asch W, Emre S. Combined liver kidney transplantation: critical analysis of a single-center experience. Transplantation Proceedings 2011, 43: 901-4. PMID: 21486624, DOI: 10.1016/j.transproceed.2011.02.033.
- Cimsit B, Assis D, Caldwell C, Arvelakis A, Taddei T, Kulkarni S, Schilsky M, Emre S. Successful treatment of fibrosing cholestatic hepatitis after liver transplantation. Transplantation Proceedings 2011, 43: 905-8. PMID: 21486625, DOI: 10.1016/j.transproceed.2011.02.034.
- Renal transplantation for nephrogenic systemic fibrosis: a case report and review of the literature.Cuffy MC, Singh M, Formica R, Simmons E, Abu Alfa AK, Carlson K, Girardi M, Cowper SE, Kulkarni S. Renal transplantation for nephrogenic systemic fibrosis: a case report and review of the literature. Nephrology, Dialysis, Transplantation : Official Publication Of The European Dialysis And Transplant Association - European Renal Association 2011, 26: 1099-101. PMID: 21079195, DOI: 10.1093/ndt/gfq693.
- Kulkarni S, Emre S, Arvelakis A, Asch W, Bia M, Formica R, Israel G. Multidetector CT angiography in living donor renal transplantation: accuracy and discrepancies in right venous anatomy. Clinical Transplantation 2011, 25: 77-82. PMID: 20070320, DOI: 10.1111/j.1399-0012.2009.01193.x.
- Bia M, Adey DB, Bloom RD, Chan L, Kulkarni S, Tomlanovich S. KDOQI US commentary on the 2009 KDIGO clinical practice guideline for the care of kidney transplant recipients. American Journal Of Kidney Diseases : The Official Journal Of The National Kidney Foundation 2010, 56: 189-218. PMID: 20598411, DOI: 10.1053/j.ajkd.2010.04.010.
- Caldwell C, Werdiger N, Jakab S, Schilsky M, Arvelakis A, Kulkarni S, Emre S. Use of model for end-stage liver disease exception points for early liver transplantation and successful reversal of hepatic myelopathy with a review of the literature. Liver Transplantation : Official Publication Of The American Association For The Study Of Liver Diseases And The International Liver Transplantation Society 2010, 16: 818-26. PMID: 20583082, DOI: 10.1002/lt.22077.
- Tichy EM, Medwid AJ, Mills EA, Formica RN, Kulkarni S. Significant sirolimus and dronedarone interaction in a kidney transplant recipient. The Annals Of Pharmacotherapy 2010, 44: 1338-41. PMID: 20484171, DOI: 10.1345/aph.1P114.
- Formica RN, Asch WS, Wagner KR, Kulkarni S. Kidney transplantation and HIV: does recipient privacy outweigh the donor's right to information? Clinical Journal Of The American Society Of Nephrology : CJASN 2010, 5: 924-8. PMID: 20203162, PMCID: PMC2863980, DOI: 10.2215/CJN.06820909.
- Parekh AM, Gordon EJ, Garg AX, Waterman AD, Kulkarni S, Parikh CR. Living kidney donor informed consent practices vary between US and non-US centers. Nephrology, Dialysis, Transplantation : Official Publication Of The European Dialysis And Transplant Association - European Renal Association 2008, 23: 3316-24. PMID: 18599559, PMCID: PMC2720811, DOI: 10.1093/ndt/gfn295.
- Friedman AL, Geoghegan SR, Sowers NM, Kulkarni S, Formica RN. Medication errors in the outpatient setting: classification and root cause analysis. Archives Of Surgery (Chicago, Ill. : 1960) 2007, 142: 278-83; discussion 284. PMID: 17372053, DOI: 10.1001/archsurg.142.3.278.
- Kulkarni S, Cronin DC. Ethics in liver transplantation. Seminars In Liver Disease 2006, 26: 234-8. PMID: 16850372, DOI: 10.1055/s-2006-947299.
- Kulkarni S, Cronin DC. Ethical tensions in solid organ transplantation: the price of success. World Journal Of Gastroenterology : WJG 2006, 12: 3259-64. PMID: 16718849, PMCID: PMC4087972, DOI: 10.3748/wjg.v12.i20.3259.
- Kulkarni S, Malagò M, Cronin DC. Living donor liver transplantation for pediatric and adult recipients. Nature Clinical Practice. Gastroenterology & Hepatology 2006, 3: 149-57. PMID: 16511549, DOI: 10.1038/ncpgasthep0437.
- Schaffer RL, Kulkarni S, Harper A, Millis JM, Cronin DC. The sickest first? Disparities with model for end-stage liver disease-based organ allocation: one region's experience. Liver Transplantation : Official Publication Of The American Association For The Study Of Liver Diseases And The International Liver Transplantation Society 2003, 9: 1211-5. PMID: 14586883, DOI: 10.1053/jlts.2003.50192.
- Kulkarni S, Naureckas E, Cronin DC. Solid-organ transplant recipients treated with drotrecogin alfa (activated) for severe sepsis. Transplantation 2003, 75: 899-901. PMID: 12660522, DOI: 10.1097/01.TP.0000054842.34916.E8.
- Kulkarni S, Holman PO, Kopelan A, van Seventer GA, van Seventer JM, Kranz DM, Woodle ES. Programmed cell death signaling via cell-surface expression of a single-chain antibody transgene. Transplantation 2000, 69: 1209-17. PMID: 10762228, DOI: 10.1097/00007890-200003270-00028.
- O'Herrin SM, Kulkarni S, Kenealy WR, Fechner JH, Sollinger H, Schneck JP, Burlingham WJ. Expression of human recombinant beta 2-microglobulin by Aspergillus nidulans and its activity. Human Immunology 1996, 51: 63-72. PMID: 8960907.
- Yale-New Haven Transplantation CenterYale Physicians Building800 Howard Avenue, Ste 3rd floorNew Haven, CT 06519
- Yale Transplant & ImmunologyFarnam Memorial Building310 Cedar StreetNew Haven, CT 06510
- Yale-New Haven Transplantation CenterYale Physicians Building800 Howard Avenue, Ste 3rd floorNew Haven, CT 06519
- Yale Transplant & ImmunologyFarnam Memorial Building310 Cedar StreetNew Haven, CT 06510