Yale Cancer Center
Yale New Haven Hospital
20 York Street, Ste North Pavilion 7
New Haven, CT 06510
- Yale Cancer CenterYale New Haven Hospital20 York Street, Ste North Pavilion 7New Haven, CT 06510
Iris Isufi, MD
Medical Oncology, Hematology & Oncology
Telehealth is available
Patient type treated
Adult
Accepting new patients
Yes
Referral required
From patients or physicians
Titles
- Associate Professor of Medicine (Hematology)
- Co-Director Adult CAR T-Cell Therapy Program, Hematology
- Co-Leader, Cellular Therapy Disease Aligned Research Team (DART), Yale Cancer Center
- Co-Chair, Cellular Therapy (CT)-SAFE Committee, Yale Cancer Center
Education & Training
- FellowshipYale University School of Medicine (2011)
- ResidencyAlbert Einstein College of Medicine/Montefiore Medical Center (2007)
- MDState University of New York at Stony Brook (2004)
- BAThe College of Saint Rose, Albany, NY, 2000, Biology (2000)
Languages Spoken
- English
- Italiano (Italian)
- Español (Spanish)
Additional Information
Honors & Recognitions
- ASCO/AACR Methods in Clinical Cancer Research Workshop Fellow, Vail, CO: AACR (2008)
- Outstanding House Officer in Internal Medicine Award: Albert Einstein College of Medicine/Montefiore Medical Center (2007)
- The Kijeon Yoo Award for Determination in Pursuit of a Medical Education: Stony Brook University School of Medicine (2004)
- Medical School Merit-Based Scholarship: Stony Brook University School of Medicine (2004)
Publications
- Halwani AS, Panizo C, Isufi I, Herrera AF, Okada CY, Cull EH, Kis B, Chaves JM, Bartlett NL, Ai W, de la Cruz-Merino L, Bryan LJ, Houot R, Linton K, Briones J, Chau I, von Keudell GR, Lu H, Yakovich A, Chen M, Meulen Jh T, Yurasov S, Hsu FJ, Flowers CR. Phase 1/2 study of intratumoral G100 (TLR4 agonist) with or without pembrolizumab in follicular lymphoma. Leukemia & Lymphoma 2022, 63: 821-833. PMID: 34865586, DOI: 10.1080/10428194.2021.2010057.
- Holowka T, Cheung H, Malinis M, Gan G, Deng Y, Perreault S, Isufi I, Azar MM. Incidence and associated risk factors for invasive fungal infections and other serious infections in patients on ibrutinib. Journal Of Infection And Chemotherapy : Official Journal Of The Japan Society Of Chemotherapy 2021, 27: 1700-1705. PMID: 34389223, DOI: 10.1016/j.jiac.2021.08.005.
- Perreault S, Schiffer M, Clinchy-Jarmoszko V, Bocchetta N, Barbarotta L, Abdelghany O, Foss F, Huntington S, Seropian S, Isufi I. Mitigating the risk of COVID-19 exposure by transitioning from clinic-based to home-based immune globulin infusion. American Journal Of Health-system Pharmacy : AJHP : Official Journal Of The American Society Of Health-System Pharmacists 2021, 78: 1112-1117. PMID: 33617630, PMCID: PMC7929449, DOI: 10.1093/ajhp/zxab072.
- Isufi I, Seropian S, Gowda L, Wilson LD, Roberts K, Girardi M, Perreault S, Foss F. Outcomes for allogeneic stem cell transplantation in refractory mycosis fungoides and primary cutaneous gamma Delta T cell lymphomas. Leukemia & Lymphoma 2020, 61: 2955-2961. PMID: 32643494, DOI: 10.1080/10428194.2020.1790555.
- Patel KK, Isufi I, Kothari S, Foss F, Huntington S. Cost-effectiveness of polatuzumab vedotin in relapsed or refractory diffuse large B-cell lymphoma. Leukemia & Lymphoma 2020, 61: 3387-3394. PMID: 32835553, DOI: 10.1080/10428194.2020.1808208.
- Foss FM, Rubinowitz A, Landry ML, Isufi I, Gowda L, Seropian S, Perreault S, Shenoi SV. Attenuated Novel SARS Coronavirus 2 Infection in an Allogeneic Hematopoietic Stem Cell Transplant Patient on Ruxolitinib. Clinical Lymphoma, Myeloma & Leukemia 2020, 20: 720-723. PMID: 32727701, PMCID: PMC7316063, DOI: 10.1016/j.clml.2020.06.014.
- Patel KK, Isufi I, Kothari S, Davidoff AJ, Gross CP, Huntington SF. Cost-effectiveness of first-line vs third-line ibrutinib in patients with untreated chronic lymphocytic leukemia. Blood 2020, 136: 1946-1955. PMID: 32518952, DOI: 10.1182/blood.2020004922.
- Bewersdorf JP, Shallis RM, Gowda L, Wei W, Hager K, Isufi I, Kim TK, Pillai MM, Seropian S, Podoltsev NA, Gore SD, Siddon AJ, Zeidan AM. Clinical outcomes and characteristics of patients with TP53-mutated acute myeloid leukemia or myelodysplastic syndromes: a single center experience. Leukemia & Lymphoma 2020, 61: 2180-2190. PMID: 32362171, PMCID: PMC7603787, DOI: 10.1080/10428194.2020.1759051.
- Perreault S, McManus D, Bar N, Foss F, Gowda L, Isufi I, Seropian S, Malinis M, Topal JE. The impact of a multimodal approach to vancomycin discontinuation in hematopoietic stem cell transplant recipients (HSCT) with febrile neutropenia (FN). Transplant Infectious Disease : An Official Journal Of The Transplantation Society 2019, 21: e13059. PMID: 30737868, DOI: 10.1111/tid.13059.
- Kim TK, DeVeaux M, Stahl M, Perreault S, Isufi I, Cooper D, Foss F, Shlomchik W, Zelterman D, Zeidan AM, Seropian S. Long-term follow-up of a single institution pilot study of sirolimus, tacrolimus, and short course methotrexate for graft versus host disease prophylaxis in mismatched unrelated donor allogeneic stem cell transplantation. Annals Of Hematology 2019, 98: 237-240. PMID: 30027436, DOI: 10.1007/s00277-018-3427-1.
- Cyrenne BM, Gibson JF, Subtil A, Girardi M, Isufi I, Seropian S, Foss F. Transplantation in the Treatment of Primary Cutaneous Aggressive Epidermotropic Cytotoxic CD8-Positive T-Cell Lymphoma. Clinical Lymphoma, Myeloma & Leukemia 2018, 18: e85-e93. PMID: 29223388, DOI: 10.1016/j.clml.2017.11.004.
- Perreault S, Baker J, Medoff E, Pratt K, Foss F, Isufi I, Seropian S, Cooper DL. Infusion reactions are common after high-dose carmustine in BEAM chemotherapy and are not reduced by lengthening the time of administration. Supportive Care In Cancer : Official Journal Of The Multinational Association Of Supportive Care In Cancer 2017, 25: 205-208. PMID: 27614867, DOI: 10.1007/s00520-016-3399-4.
- Nadeau M, Perreault S, Seropian S, Foss F, Isufi I, Cooper DL. The use of basiliximab-infliximab combination for the treatment of severe gastrointestinal acute GvHD. Bone Marrow Transplantation 2016, 51: 273-6. PMID: 26479982, DOI: 10.1038/bmt.2015.247.
- Lansigan F, Isufi I, Tagoe CE. Microangiopathic haemolytic anaemia resembling thrombotic thrombocytopenic purpura in systemic lupus erythematosus: the role of ADAMTS13. Rheumatology (Oxford, England) 2011, 50: 824-9. PMID: 21149242, DOI: 10.1093/rheumatology/keq395.
- Saif MW, Isufi I, Peccerillo J, Syrigos KN. Cerebrovascular accidents associated with sorafenib in hepatocellular carcinoma. Gastroenterology Research And Practice 2011, 2011: 616080. PMID: 21687621, PMCID: PMC3113260, DOI: 10.1155/2011/616080.
- Saif MW, Syrigos K, Kaley K, Isufi I. Role of pregabalin in treatment of oxaliplatin-induced sensory neuropathy. Anticancer Research 2010, 30: 2927-33. PMID: 20683034.
- Isufi I, Seetharam M, Zhou L, Sohal D, Opalinska J, Pahanish P, Verma A. Transforming growth factor-beta signaling in normal and malignant hematopoiesis. Journal Of Interferon & Cytokine Research : The Official Journal Of The International Society For Interferon And Cytokine Research 2007, 27: 543-52. PMID: 17651015, DOI: 10.1089/jir.2007.0009.
Patient Care Organizations
Titles
- Associate Professor of Medicine (Hematology)
- Co-Director Adult CAR T-Cell Therapy Program, Hematology
- Co-Leader, Cellular Therapy Disease Aligned Research Team (DART), Yale Cancer Center
- Co-Chair, Cellular Therapy (CT)-SAFE Committee, Yale Cancer Center
Education & Training
- FellowshipYale University School of Medicine (2011)
- ResidencyAlbert Einstein College of Medicine/Montefiore Medical Center (2007)
- MDState University of New York at Stony Brook (2004)
- BAThe College of Saint Rose, Albany, NY, 2000, Biology (2000)
Languages Spoken
- English
- Italiano (Italian)
- Español (Spanish)
Additional Information
Honors & Recognitions
- ASCO/AACR Methods in Clinical Cancer Research Workshop Fellow, Vail, CO: AACR (2008)
- Outstanding House Officer in Internal Medicine Award: Albert Einstein College of Medicine/Montefiore Medical Center (2007)
- The Kijeon Yoo Award for Determination in Pursuit of a Medical Education: Stony Brook University School of Medicine (2004)
- Medical School Merit-Based Scholarship: Stony Brook University School of Medicine (2004)
Publications
- Halwani AS, Panizo C, Isufi I, Herrera AF, Okada CY, Cull EH, Kis B, Chaves JM, Bartlett NL, Ai W, de la Cruz-Merino L, Bryan LJ, Houot R, Linton K, Briones J, Chau I, von Keudell GR, Lu H, Yakovich A, Chen M, Meulen Jh T, Yurasov S, Hsu FJ, Flowers CR. Phase 1/2 study of intratumoral G100 (TLR4 agonist) with or without pembrolizumab in follicular lymphoma. Leukemia & Lymphoma 2022, 63: 821-833. PMID: 34865586, DOI: 10.1080/10428194.2021.2010057.
- Holowka T, Cheung H, Malinis M, Gan G, Deng Y, Perreault S, Isufi I, Azar MM. Incidence and associated risk factors for invasive fungal infections and other serious infections in patients on ibrutinib. Journal Of Infection And Chemotherapy : Official Journal Of The Japan Society Of Chemotherapy 2021, 27: 1700-1705. PMID: 34389223, DOI: 10.1016/j.jiac.2021.08.005.
- Perreault S, Schiffer M, Clinchy-Jarmoszko V, Bocchetta N, Barbarotta L, Abdelghany O, Foss F, Huntington S, Seropian S, Isufi I. Mitigating the risk of COVID-19 exposure by transitioning from clinic-based to home-based immune globulin infusion. American Journal Of Health-system Pharmacy : AJHP : Official Journal Of The American Society Of Health-System Pharmacists 2021, 78: 1112-1117. PMID: 33617630, PMCID: PMC7929449, DOI: 10.1093/ajhp/zxab072.
- Isufi I, Seropian S, Gowda L, Wilson LD, Roberts K, Girardi M, Perreault S, Foss F. Outcomes for allogeneic stem cell transplantation in refractory mycosis fungoides and primary cutaneous gamma Delta T cell lymphomas. Leukemia & Lymphoma 2020, 61: 2955-2961. PMID: 32643494, DOI: 10.1080/10428194.2020.1790555.
- Patel KK, Isufi I, Kothari S, Foss F, Huntington S. Cost-effectiveness of polatuzumab vedotin in relapsed or refractory diffuse large B-cell lymphoma. Leukemia & Lymphoma 2020, 61: 3387-3394. PMID: 32835553, DOI: 10.1080/10428194.2020.1808208.
- Foss FM, Rubinowitz A, Landry ML, Isufi I, Gowda L, Seropian S, Perreault S, Shenoi SV. Attenuated Novel SARS Coronavirus 2 Infection in an Allogeneic Hematopoietic Stem Cell Transplant Patient on Ruxolitinib. Clinical Lymphoma, Myeloma & Leukemia 2020, 20: 720-723. PMID: 32727701, PMCID: PMC7316063, DOI: 10.1016/j.clml.2020.06.014.
- Patel KK, Isufi I, Kothari S, Davidoff AJ, Gross CP, Huntington SF. Cost-effectiveness of first-line vs third-line ibrutinib in patients with untreated chronic lymphocytic leukemia. Blood 2020, 136: 1946-1955. PMID: 32518952, DOI: 10.1182/blood.2020004922.
- Bewersdorf JP, Shallis RM, Gowda L, Wei W, Hager K, Isufi I, Kim TK, Pillai MM, Seropian S, Podoltsev NA, Gore SD, Siddon AJ, Zeidan AM. Clinical outcomes and characteristics of patients with TP53-mutated acute myeloid leukemia or myelodysplastic syndromes: a single center experience. Leukemia & Lymphoma 2020, 61: 2180-2190. PMID: 32362171, PMCID: PMC7603787, DOI: 10.1080/10428194.2020.1759051.
- Perreault S, McManus D, Bar N, Foss F, Gowda L, Isufi I, Seropian S, Malinis M, Topal JE. The impact of a multimodal approach to vancomycin discontinuation in hematopoietic stem cell transplant recipients (HSCT) with febrile neutropenia (FN). Transplant Infectious Disease : An Official Journal Of The Transplantation Society 2019, 21: e13059. PMID: 30737868, DOI: 10.1111/tid.13059.
- Kim TK, DeVeaux M, Stahl M, Perreault S, Isufi I, Cooper D, Foss F, Shlomchik W, Zelterman D, Zeidan AM, Seropian S. Long-term follow-up of a single institution pilot study of sirolimus, tacrolimus, and short course methotrexate for graft versus host disease prophylaxis in mismatched unrelated donor allogeneic stem cell transplantation. Annals Of Hematology 2019, 98: 237-240. PMID: 30027436, DOI: 10.1007/s00277-018-3427-1.
- Cyrenne BM, Gibson JF, Subtil A, Girardi M, Isufi I, Seropian S, Foss F. Transplantation in the Treatment of Primary Cutaneous Aggressive Epidermotropic Cytotoxic CD8-Positive T-Cell Lymphoma. Clinical Lymphoma, Myeloma & Leukemia 2018, 18: e85-e93. PMID: 29223388, DOI: 10.1016/j.clml.2017.11.004.
- Perreault S, Baker J, Medoff E, Pratt K, Foss F, Isufi I, Seropian S, Cooper DL. Infusion reactions are common after high-dose carmustine in BEAM chemotherapy and are not reduced by lengthening the time of administration. Supportive Care In Cancer : Official Journal Of The Multinational Association Of Supportive Care In Cancer 2017, 25: 205-208. PMID: 27614867, DOI: 10.1007/s00520-016-3399-4.
- Nadeau M, Perreault S, Seropian S, Foss F, Isufi I, Cooper DL. The use of basiliximab-infliximab combination for the treatment of severe gastrointestinal acute GvHD. Bone Marrow Transplantation 2016, 51: 273-6. PMID: 26479982, DOI: 10.1038/bmt.2015.247.
- Lansigan F, Isufi I, Tagoe CE. Microangiopathic haemolytic anaemia resembling thrombotic thrombocytopenic purpura in systemic lupus erythematosus: the role of ADAMTS13. Rheumatology (Oxford, England) 2011, 50: 824-9. PMID: 21149242, DOI: 10.1093/rheumatology/keq395.
- Saif MW, Isufi I, Peccerillo J, Syrigos KN. Cerebrovascular accidents associated with sorafenib in hepatocellular carcinoma. Gastroenterology Research And Practice 2011, 2011: 616080. PMID: 21687621, PMCID: PMC3113260, DOI: 10.1155/2011/616080.
- Saif MW, Syrigos K, Kaley K, Isufi I. Role of pregabalin in treatment of oxaliplatin-induced sensory neuropathy. Anticancer Research 2010, 30: 2927-33. PMID: 20683034.
- Isufi I, Seetharam M, Zhou L, Sohal D, Opalinska J, Pahanish P, Verma A. Transforming growth factor-beta signaling in normal and malignant hematopoiesis. Journal Of Interferon & Cytokine Research : The Official Journal Of The International Society For Interferon And Cytokine Research 2007, 27: 543-52. PMID: 17651015, DOI: 10.1089/jir.2007.0009.
Patient Care Organizations
Yale Cancer Center
Yale New Haven Hospital
20 York Street, Ste North Pavilion 7
New Haven, CT 06510
- Yale Cancer CenterYale New Haven Hospital20 York Street, Ste North Pavilion 7New Haven, CT 06510