Ian Krop, MD, PhD

Ian Krop, MD, PhD, is a professor of internal medicine, specializing in medical oncology, at Yale School of Medicine. He is a Yale Medicine specialist, with expertise in the management of breast cancer. Among his leadership roles at Yale Cancer Center, Dr. Krop serves as Associate Cancer Center Director for Clinical Research, Director of the Yale Cancer Center Clinical Trials Office, and Chief Clinical Research Officer.

Dr. Krop's research interests include the treatment of HER2-positive breast cancer through the investigation of various therapies, evaluation of genomic tools, and analysis of patient-reported outcomes. He participates in clinical trials that examine the role of neoadjuvant therapies in cancer treatment and ways to manage of spread of cancer to the brain. His work also examines patient-reported outcomes in breast cancer clinical trials and the correlation between the PIK3CA mutation and breast cancer outcomes.

Dr. Krop's research team has been awarded with grants from the National Cancer Institute, Susan G. Komen Breast Cancer Foundation, the Breast Cancer Research Foundation, and the American Association for Cancer Research. His work has significantly influenced patient care and medical education, leading to an improved understanding of resistance to HER2-directed therapies, the identification of potential tumor suppressors, and strategies to overcome residual disease in HER2-positive breast cancer.