- Yale Physicians Building800 Howard Avenue, Fl 2ndNew Haven, CT 06519
Edward J Miller, MD, PhD
Biography
Edward J. Miller, MD, PhD, treats chronic heart including infiltrative cardiomyopathies. “The Yale Medicine Cardiomyopathy Inherited Cardiovascular Disease Program has a wonderful interdisciplinary team of experts in the diagnosis and management of infiltrative cardiomyopathies,” says Dr. Miller, who also directs the clinical nuclear cardiology laboratory at Yale New Haven Hospital
An expert at using imaging to diagnose and treat heart disease, Dr. Miller is especially interested in the use of new imaging techniques in cardiac sarcoidosis (an inflammatory disorder) and cardiac amyloidosis (a disorder of protein deposits). He is also focused on the role of obesity in certain types of heart disease.
Dr. Miller is an assistant professor of medicine, and of radiology and biomedical imaging at Yale School of Medicine.
Titles
- Associate Professor of Medicine (Cardiovascular Medicine)
- Vice Chief of Cardiovascular Medicine (Education), Cardiovascular Medicine
- Associate Professor of Medicine and Radiology
- Director, Nuclear Cardiology, Cardiovascular Medicine
- Director, Cardiology Fellowship Program, Cardiovascular Medicine
Education & Training
- Clinical FellowYale School of Medicine (2008)
- PhDYale University School of Medicine, Investigative Medicine (2008)
- Research FellowYale School of Medicine (2005)
- ResidentYale-New Haven Hospital (2003)
- InternYale-New Haven Hospital (2000)
- MDLoyola-Stritch School of Medicine, Medicine (1999)
- BSUniversity of Notre Dame, Preprofessional Studies (1994)
Additional Information
- Fellow, American College of Cardiology: American College of Cardiology (2017)
- Fellow, American Society of Nuclear Cardiology: American Society of Nuclear Cardiology (2014)
- Navy and Marine Corps Commendation Medal: United States Navy (2001)
- Navy Combat Action Ribbon: United States Navy (2001)
- Alpha Omega Alpha: (1999)
- Society of Nuclear Medicine and Molecular Imaging - Cardiovascular Council (2015 - Present): Board of Directors
- Certification Board of Nuclear Cardiology (2013 - Present): Board of Directors
- American Society of Nuclear Cardiology (2009 - 2010): Leadership Development Program
- Al-Mallah MH, Bateman TM, Branch KR, Crean A, Gingold EL, Thompson RC, McKenney SE, Miller EJ, Murthy VL, Nieman K, Villines TC, Yester MV, Einstein AJ, Mahmarian JJ. 2022 ASNC/AAPM/SCCT/SNMMI guideline for the use of CT in hybrid nuclear/CT cardiac imaging. Journal Of Nuclear Cardiology : Official Publication Of The American Society Of Nuclear Cardiology 2022 PMID: 36056224, DOI: 10.1007/s12350-022-03089-z.
- Chen X, Zhou B, Xie H, Miao T, Liu H, Holler W, Lin M, Miller EJ, Carson RE, Sinusas AJ, Liu C. DuDoSS: Deep-Learning-Based Dual-Domain sinogram synthesis from Sparsely-sampled projections of cardiac SPECT. Medical Physics 2022 PMID: 36048541, DOI: 10.1002/mp.15958.
- Sperry BW, Bateman TM, Akin EA, Bravo PE, Chen W, Dilsizian V, Hyafil F, Khor YM, Miller RJH, Slart RHJA, Slomka P, Verberne H, Miller EJ, Liu C. Hot spot imaging in cardiovascular diseases: an information statement from SNMMI, ASNC, and EANM. Journal Of Nuclear Cardiology : Official Publication Of The American Society Of Nuclear Cardiology 2022 PMID: 35864433, DOI: 10.1007/s12350-022-02985-8.
- Sperry BW, Bateman TM, Akin EA, Bravo PE, Chen W, Dilsizian V, Hyafil F, Khor YM, Miller RJH, Slart RHJA, Slomka P, Verberne H, Miller EJ, Liu C. Hot Spot Imaging in Cardiovascular Diseases: An Information Statement from SNMMI, ASNC, and EANM. Journal Of Nuclear Medicine : Official Publication, Society Of Nuclear Medicine 2022 PMID: 35863895, DOI: 10.2967/jnumed.122.264311.
- Rios R, Miller RJH, Hu LH, Otaki Y, Singh A, Diniz M, Sharir T, Einstein AJ, Fish MB, Ruddy TD, Kaufmann PA, Sinusas AJ, Miller EJ, Bateman TM, Dorbala S, DiCarli M, Van Kriekinge S, Kavanagh P, Parekh T, Liang JX, Dey D, Berman DS, Slomka P. Determining a minimum set of variables for machine learning cardiovascular event prediction: results from REFINE SPECT registry. Cardiovascular Research 2022, 118: 2152-2164. PMID: 34259870, PMCID: PMC9302886, DOI: 10.1093/cvr/cvab236.
- Miller EJ, Campisi R, Shah NR, McMahon S, Cuddy S, Gallegos-Kattan C, Maurer MS, Damy T, Slart RHJA, Bhatia K, Einstein AJ. Radiopharmaceutical supply disruptions and the use of 99mTc-hydroxymethylene diphosphonate as an alternative to 99mTc-pyrophosphate for the diagnosis of transthyretin cardiac amyloidosis: An ASNC Information Statement. Journal Of Nuclear Cardiology : Official Publication Of The American Society Of Nuclear Cardiology 2022 PMID: 35838892, PMCID: PMC9285188, DOI: 10.1007/s12350-022-03059-5.
- Dorbala S, Ando Y, Bokhari S, Dispenzieri A, Falk RH, Ferrari VA, Fontana M, Gheysens O, Gillmore JD, Glaudemans AWJM, Hanna MA, Hazenberg BPC, Kristen AV, Kwong RY, Maurer MS, Merlini G, Miller EJ, Moon JC, Murthy VL, Quarta CC, Rapezzi C, Ruberg FL, Shah SJ, Slart RHJA, Verberne HJ, Bourque JM. Addendum to ASNC/AHA/ASE/EANM/HFSA/ISA/SCMR/SNMMI Expert Consensus Recommendations for Multimodality Imaging in Cardiac Amyloidosis: Part 1 of 2-Evidence Base and Standardized Methods of Imaging. Journal Of Cardiac Failure 2022, 28: e1-e4. PMID: 34217819, DOI: 10.1016/j.cardfail.2021.06.012.
- Chen X, Zhou B, Xie H, Shi L, Liu H, Holler W, Lin M, Liu YH, Miller EJ, Sinusas AJ, Liu C. Direct and indirect strategies of deep-learning-based attenuation correction for general purpose and dedicated cardiac SPECT. European Journal Of Nuclear Medicine And Molecular Imaging 2022, 49: 3046-3060. PMID: 35169887, PMCID: PMC9253078, DOI: 10.1007/s00259-022-05718-8.
- Miller RJH, Hauser MT, Sharir T, Einstein AJ, Fish MB, Ruddy TD, Kaufmann PA, Sinusas AJ, Miller EJ, Bateman TM, Dorbala S, Di Carli M, Huang C, Liang JX, Han D, Dey D, Berman DS, Slomka PJ. Machine learning to predict abnormal myocardial perfusion from pre-test features. Journal Of Nuclear Cardiology : Official Publication Of The American Society Of Nuclear Cardiology 2022 PMID: 35672567, DOI: 10.1007/s12350-022-03012-6.
- Damsky W, Wang A, Kim DJ, Young BD, Singh K, Murphy MJ, Daccache J, Clark A, Ayasun R, Ryu C, McGeary MK, Odell ID, Fazzone-Chettiar R, Pucar D, Homer R, Gulati M, Miller EJ, Bosenberg M, Flavell RA, King B. Inhibition of type 1 immunity with tofacitinib is associated with marked improvement in longstanding sarcoidosis. Nature Communications 2022, 13: 3140. PMID: 35668129, PMCID: PMC9170782, DOI: 10.1038/s41467-022-30615-x.
- Otaki Y, Singh A, Kavanagh P, Miller RJH, Parekh T, Tamarappoo BK, Sharir T, Einstein AJ, Fish MB, Ruddy TD, Kaufmann PA, Sinusas AJ, Miller EJ, Bateman TM, Dorbala S, Di Carli M, Cadet S, Liang JX, Dey D, Berman DS, Slomka PJ. Clinical Deployment of Explainable Artificial Intelligence of SPECT for Diagnosis of Coronary Artery Disease. JACC. Cardiovascular Imaging 2022, 15: 1091-1102. PMID: 34274267, PMCID: PMC9020794, DOI: 10.1016/j.jcmg.2021.04.030.
- Pathak GA, De Lillo A, Wendt FR, De Angelis F, Koller D, Cabrera Mendoza B, Jacoby D, Miller EJ, Buxbaum JN, Polimanti R. The integration of genetically-regulated transcriptomics and electronic health records highlights a pattern of medical outcomes related to increased hepatic transthyretin expression. Amyloid : The International Journal Of Experimental And Clinical Investigation : The Official Journal Of The International Society Of Amyloidosis 2022, 29: 110-119. PMID: 34935565, PMCID: PMC9213571, DOI: 10.1080/13506129.2021.2018678.
- Rios R, Miller RJH, Manral N, Sharir T, Einstein AJ, Fish MB, Ruddy TD, Kaufmann PA, Sinusas AJ, Miller EJ, Bateman TM, Dorbala S, Di Carli M, Van Kriekinge SD, Kavanagh PB, Parekh T, Liang JX, Dey D, Berman DS, Slomka PJ. Handling missing values in machine learning to predict patient-specific risk of adverse cardiac events: Insights from REFINE SPECT registry. Computers In Biology And Medicine 2022, 145: 105449. PMID: 35381453, PMCID: PMC9117456, DOI: 10.1016/j.compbiomed.2022.105449.
- Tamarappoo BK, Otaki Y, Sharir T, Hu LH, Gransar H, Einstein AJ, Fish MB, Ruddy TD, Kaufmann P, Sinusas AJ, Miller EJ, Bateman TM, Dorbala S, Di Carli M, Eisenberg E, Liang JX, Dey D, Berman DS, Slomka PJ. Differences in Prognostic Value of Myocardial Perfusion Single-Photon Emission Computed Tomography Using High-Efficiency Solid-State Detector Between Men and Women in a Large International Multicenter Study. Circulation. Cardiovascular Imaging 2022, 15: e012741. PMID: 35727872, PMCID: PMC9307118, DOI: 10.1161/CIRCIMAGING.121.012741.
- Wang SY, Adejumo P, See C, Onuma OK, Miller EJ, Spatz ES. Characteristics of patients referred to a cardiovascular disease clinic for post-acute sequelae of SARS-CoV-2 infection. American Heart Journal Plus : Cardiology Research And Practice 2022, 18: 100176. PMID: 35856065, PMCID: PMC9277988, DOI: 10.1016/j.ahjo.2022.100176.
- Miller RJH, Kuronuma K, Singh A, Otaki Y, Hayes S, Chareonthaitawee P, Kavanagh P, Parekh T, Tamarappoo BK, Sharir T, Einstein AJ, Fish MB, Ruddy TD, Kaufmann PA, Sinusas AJ, Miller EJ, Bateman T, Dorbala S, Di Carli MF, Cadet S, Liang JX, Dey D, Berman DS, Slomka PJ. Explainable Deep Learning Improves Physician Interpretation of Myocardial Perfusion Imaging. Journal Of Nuclear Medicine : Official Publication, Society Of Nuclear Medicine 2022 PMID: 35512997, DOI: 10.2967/jnumed.121.263686.
- Klein E, Miller RJH, Sharir T, Einstein AJ, Fish MB, Ruddy TD, Kaufmann PA, Sinusas AJ, Miller EJ, Bateman TM, Dorbala S, Di Carli M, Otaki Y, Gransar H, Liang JX, Dey D, Berman DS, Slomka PJ. Automated quantitative analysis of CZT SPECT stratifies cardiovascular risk in the obese population: Analysis of the REFINE SPECT registry. Journal Of Nuclear Cardiology : Official Publication Of The American Society Of Nuclear Cardiology 2022, 29: 727-736. PMID: 32929639, PMCID: PMC8497048, DOI: 10.1007/s12350-020-02334-7.
- Higgins AY, Annapureddy AR, Wang Y, Minges KE, Bellumkonda L, Lampert R, Rosenfeld LE, Jacoby DL, Curtis JP, Miller EJ, Freeman JV. Risk and predictors of mortality after implantable cardioverter-defibrillator implantation in patients with sarcoid cardiomyopathy. American Heart Journal 2022, 246: 21-31. PMID: 34968442, DOI: 10.1016/j.ahj.2021.12.011.
- Han D, Rozanski A, Miller RJH, Sharir T, Einstein AJ, Fish MB, Ruddy TD, Kaufmann PA, Sinusas AJ, Miller EJ, Bateman TM, Dorbala S, Di Carli M, Liang JX, Dey D, Berman DS, Slomka PJ. Prevalence and predictors of automatically quantified myocardial ischemia within a multicenter international registry. Journal Of Nuclear Cardiology : Official Publication Of The American Society Of Nuclear Cardiology 2022 PMID: 35174442, PMCID: PMC9378748, DOI: 10.1007/s12350-021-02829-x.
- Wu J, Boutagy NE, Cai Z, Lin SF, Zheng MQ, Feher A, Stendahl JC, Kapinos M, Gallezot JD, Liu H, Mulnix T, Zhang W, Lindemann M, Teng JK, Miller EJ, Huang Y, Carson RE, Sinusas AJ, Liu C. Feasibility study of PET dynamic imaging of [18F]DHMT for quantification of reactive oxygen species in the myocardium of large animals. Journal Of Nuclear Cardiology : Official Publication Of The American Society Of Nuclear Cardiology 2022, 29: 216-225. PMID: 32415628, PMCID: PMC7666654, DOI: 10.1007/s12350-020-02184-3.
- Murray MF, Miller EJ. Can We Manage Presymptomatic TTR V142I Related Risk? JACC. Heart Failure 2022, 10: 139-141. PMID: 35115087, DOI: 10.1016/j.jchf.2021.10.009.
- Shi L, Lu Y, Dvornek N, Weyman CA, Miller EJ, Sinusas AJ, Liu C. Automatic Inter-Frame Patient Motion Correction for Dynamic Cardiac PET Using Deep Learning. IEEE Transactions On Medical Imaging 2021, 40: 3293-3304. PMID: 34018932, PMCID: PMC8670362, DOI: 10.1109/TMI.2021.3082578.
- Han D, Rozanski A, Gransar H, Tzolos E, Miller RJH, Sharir T, Einstein AJ, Fish MB, Ruddy TD, Kaufmann PA, Sinusas AJ, Miller EJ, Bateman TM, Dorbala S, Di Carli M, Liang JX, Hu LH, Dey D, Berman DS, Slomka PJ. Comparison of diabetes to other prognostic predictors among patients referred for cardiac stress testing: A contemporary analysis from the REFINE SPECT Registry. Journal Of Nuclear Cardiology : Official Publication Of The American Society Of Nuclear Cardiology 2021 PMID: 34757571, PMCID: PMC9085969, DOI: 10.1007/s12350-021-02810-8.
- Park J, Young BD, Miller EJ. Potential novel imaging targets of inflammation in cardiac sarcoidosis. Journal Of Nuclear Cardiology : Official Publication Of The American Society Of Nuclear Cardiology 2021 PMID: 34734365, DOI: 10.1007/s12350-021-02838-w.
- Yang J, Shi L, Wang R, Miller EJ, Sinusas AJ, Liu CJ, Gullberg GT, Seo Y. Direct Attenuation Correction Using Deep Learning for Cardiac SPECT: A Feasibility Study. Journal Of Nuclear Medicine : Official Publication, Society Of Nuclear Medicine 2021, 62: 1645-1652. PMID: 33637586, PMCID: PMC8612332, DOI: 10.2967/jnumed.120.256396.
- Miller RJH, Sharir T, Otaki Y, Gransar H, Liang JX, Einstein AJ, Fish MB, Ruddy TD, Kaufmann PA, Sinusas AJ, Miller EJ, Bateman TM, Dorbala S, Di Carli M, Tamarappoo BK, Dey D, Berman DS, Slomka PJ. Quantitation of Poststress Change in Ventricular Morphology Improves Risk Stratification. Journal Of Nuclear Medicine : Official Publication, Society Of Nuclear Medicine 2021, 62: 1582-1590. PMID: 33712535, PMCID: PMC8612345, DOI: 10.2967/jnumed.120.260141.
- Liu H, Wu J, Shi L, Liu Y, Miller E, Sinusas A, Liu YH, Liu C. Post-reconstruction attenuation correction for SPECT myocardium perfusion imaging facilitated by deep learning-based attenuation map generation. Journal Of Nuclear Cardiology : Official Publication Of The American Society Of Nuclear Cardiology 2021 PMID: 34671940, DOI: 10.1007/s12350-021-02817-1.
- Feher A, Boutagy NE, Oikonomou EK, Thorn S, Liu YH, Miller EJ, Sinusas AJ, Hinchcliff M. Impaired Myocardial Flow Reserve on 82Rubidium Positron Emission Tomography/Computed Tomography in Patients With Systemic Sclerosis. The Journal Of Rheumatology 2021, 48: 1574-1582. PMID: 34266986, DOI: 10.3899/jrheum.210040.
- Young BD, Moreland H, Oatmen KE, Freeburg LA, Shahab Z, Herzog E, Miller EJ, Spinale FG. Cytokine Signaling and Matrix Remodeling Pathways Associated with Cardiac Sarcoidosis Disease Activity Defined Using FDG PET Imaging. International Heart Journal 2021, 62: 1096-1105. PMID: 34544982, DOI: 10.1536/ihj.21-164.
- Wendt FR, Koller D, Pathak GA, Jacoby D, Miller EJ, Polimanti R. Biobank Scale Pharmacogenomics Informs the Genetic Underpinnings of Simvastatin Use. Clinical Pharmacology And Therapeutics 2021, 110: 777-785. PMID: 33837531, PMCID: PMC8376807, DOI: 10.1002/cpt.2260.
- Feher A, Boutagy NE, Oikonomou EK, Liu YH, Miller EJ, Sinusas AJ, Hinchcliff M. Association Between Impaired Myocardial Flow Reserve on 82Rubidium Positron Emission Tomography Imaging and Adverse Events in Patients With Autoimmune Rheumatic Disease. Circulation. Cardiovascular Imaging 2021, 14: e012208. PMID: 34503339, PMCID: PMC8475774, DOI: 10.1161/CIRCIMAGING.120.012208.
- Liu H, Thorn S, Wu J, Fazzone-Chettiar R, Sandoval V, Miller EJ, Sinusas AJ, Liu YH. Quantification of myocardial blood flow (MBF) and reserve (MFR) incorporated with a novel segmentation approach: Assessments of quantitative precision and the lower limit of normal MBF and MFR in patients. Journal Of Nuclear Cardiology : Official Publication Of The American Society Of Nuclear Cardiology 2021, 28: 1236-1248. PMID: 32715416, DOI: 10.1007/s12350-020-02278-y.
- Liu H, Wu J, Miller EJ, Liu C, Yaqiang, Liu, Liu YH. Diagnostic accuracy of stress-only myocardial perfusion SPECT improved by deep learning. European Journal Of Nuclear Medicine And Molecular Imaging 2021, 48: 2793-2800. PMID: 33511425, DOI: 10.1007/s00259-021-05202-9.
- Dorbala S, Ando Y, Bokhari S, Dispenzieri A, Falk RH, Ferrari VA, Fontana M, Gheysens O, Gillmore JD, Glaudemans AWJM, Hanna MA, Hazenberg BPC, Kristen AV, Kwong RY, Maurer MS, Merlini G, Miller EJ, Moon JC, Murthy VL, Quarta CC, Rapezzi C, Ruberg FL, Shah SJ, Slart RHJA, Verberne HJ, Bourque JM. Addendum to ASNC/AHA/ASE/EANM/HFSA/ISA/SCMR/SNMMI expert consensus recommendations for multimodality imaging in cardiac amyloidosis: Part 1 of 2-evidence base and standardized methods of imaging. Journal Of Nuclear Cardiology : Official Publication Of The American Society Of Nuclear Cardiology 2021, 28: 1769-1774. PMID: 34196911, DOI: 10.1007/s12350-020-02455-z.
- Dorbala S, Ando Y, Bokhari S, Dispenzieri A, Falk RH, Ferrari VA, Fontana M, Gheysens O, Gillmore JD, Glaudemans AWJM, Hanna MA, Hazenberg BPC, Kristen AV, Kwong RY, Maurer MS, Merlini G, Miller EJ, Moon JC, Murthy VL, Quarta CC, Rapezzi C, Ruberg FL, Shah SJ, Slart RHJA, Verberne HJ, Bourque JM. Correction to: ASNC/AHA/ASE/EANM/HFSA/ISA/SCMR/SNMMI expert consensus recommendations for multimodality imaging in cardiac amyloidosis: Part 1 of 2-evidence base and standardized methods of imaging. Journal Of Nuclear Cardiology : Official Publication Of The American Society Of Nuclear Cardiology 2021, 28: 1761-1762. PMID: 34259978, DOI: 10.1007/s12350-021-02711-w.
- Dorbala S, Ando Y, Bokhari S, Dispenzieri A, Falk RH, Ferrari VA, Fontana M, Gheysens O, Gillmore JD, Glaudemans AWJM, Hanna MA, Hazenberg BPC, Kristen AV, Kwong RY, Maurer MS, Merlini G, Miller EJ, Moon JC, Murthy VL, Quarta CC, Rapezzi C, Ruberg FL, Shah SJ, Slart RHJA, Verberne HJ, Bourque JM. Correction to: ASNC/AHA/ASE/EANM/HFSA/ISA/SCMR/SNMMI Expert consensus recommendations for multimodality imaging in cardiac amyloidosis: Part 2 of 2-Diagnostic criteria and appropriate utilization. Journal Of Nuclear Cardiology : Official Publication Of The American Society Of Nuclear Cardiology 2021, 28: 1763-1767. PMID: 34279803, DOI: 10.1007/s12350-021-02712-9.
- Oikonomou EK, Van Dijk D, Parise H, Suchard MA, de Lemos J, Antoniades C, Velazquez EJ, Miller EJ, Khera R. A phenomapping-derived tool to personalize the selection of anatomical vs. functional testing in evaluating chest pain (ASSIST). European Heart Journal 2021, 42: 2536-2548. PMID: 33881513, PMCID: PMC8488385, DOI: 10.1093/eurheartj/ehab223.
- Eisenberg E, Miller RJH, Hu LH, Rios R, Betancur J, Azadani P, Han D, Sharir T, Einstein AJ, Bokhari S, Fish MB, Ruddy TD, Kaufmann PA, Sinusas AJ, Miller EJ, Bateman TM, Dorbala S, Di Carli M, Liang JX, Otaki Y, Tamarappoo BK, Dey D, Berman DS, Slomka PJ. Diagnostic safety of a machine learning-based automatic patient selection algorithm for stress-only myocardial perfusion SPECT. Journal Of Nuclear Cardiology : Official Publication Of The American Society Of Nuclear Cardiology 2021 PMID: 34228341, PMCID: PMC9020793, DOI: 10.1007/s12350-021-02698-4.
- Dorbala S, Ando Y, Bokhari S, Dispenzieri A, Falk RH, Ferrari VA, Fontana M, Gheysens O, Gillmore JD, Glaudemans AWJM, Hanna MA, Hazenberg BPC, Kristen AV, Kwong RY, Maurer MS, Merlini G, Miller EJ, Moon JC, Murthy VL, Quarta CC, Rapezzi C, Ruberg FL, Shah SJ, Slart RHJA, Verberne HJ, Bourque JM. ASNC/AHA/ASE/EANM/HFSA/ISA/SCMR/SNMMI Expert Consensus Recommendations for Multimodality Imaging in Cardiac Amyloidosis: Part 1 of 2-Evidence Base and Standardized Methods of Imaging. Circulation. Cardiovascular Imaging 2021, 14: e000029. PMID: 34196223, DOI: 10.1161/HCI.0000000000000029.
- Dorbala S, Ando Y, Bokhari S, Dispenzieri A, Falk RH, Ferrari VA, Fontana M, Gheysens O, Gillmore JD, Glaudemans AWJM, Hanna MA, Hazenberg BPC, Kristen AV, Kwong RY, Maurer MS, Merlini G, Miller EJ, Moon JC, Murthy VL, Quarta CC, Rapezzi C, Ruberg FL, Shah SJ, Slart RHJA, Verberne HJ, Bourque JM. ASNC/AHA/ASE/EANM/HFSA/ISA/SCMR/SNMMI Expert Consensus Recommendations for Multimodality Imaging in Cardiac Amyloidosis: Part 2 of 2-Diagnostic Criteria and Appropriate Utilization. Circulation. Cardiovascular Imaging 2021, 14: e000030. PMID: 34196222, DOI: 10.1161/HCI.0000000000000030.
- Kuronuma K, Miller RJH, Otaki Y, Van Kriekinge SD, Diniz MA, Sharir T, Hu LH, Gransar H, Liang JX, Parekh T, Kavanagh PB, Einstein AJ, Fish MB, Ruddy TD, Kaufmann PA, Sinusas AJ, Miller EJ, Bateman TM, Dorbala S, Di Carli M, Tamarappoo BK, Dey D, Berman DS, Slomka PJ. Prognostic Value of Phase Analysis for Predicting Adverse Cardiac Events Beyond Conventional Single-Photon Emission Computed Tomography Variables: Results From the REFINE SPECT Registry. Circulation. Cardiovascular Imaging 2021, 14: e012386. PMID: 34281372, PMCID: PMC8978932, DOI: 10.1161/CIRCIMAGING.120.012386.
- Chen X, Zhou B, Shi L, Liu H, Pang Y, Wang R, Miller EJ, Sinusas AJ, Liu C. CT-free attenuation correction for dedicated cardiac SPECT using a 3D dual squeeze-and-excitation residual dense network. Journal Of Nuclear Cardiology : Official Publication Of The American Society Of Nuclear Cardiology 2021 PMID: 34085168, DOI: 10.1007/s12350-021-02672-0.
- Liu YH, Fazzone-Chettiar R, Sandoval V, Tsatkin V, Miller EJ, Sinusas AJ. New approach for quantification of left ventricular function from low-dose gated bloodpool SPECT: Validation and comparison with conventional methods in patients. Journal Of Nuclear Cardiology : Official Publication Of The American Society Of Nuclear Cardiology 2021, 28: 939-950. PMID: 31338796, DOI: 10.1007/s12350-019-01823-8.
- Gallegos C, Oikonomou EK, Grimshaw A, Gulati M, Young BD, Miller EJ. Non-steroidal treatment of cardiac sarcoidosis: A systematic review. International Journal Of Cardiology. Heart & Vasculature 2021, 34: 100782. PMID: 33997256, PMCID: PMC8105294, DOI: 10.1016/j.ijcha.2021.100782.
- Hu LH, Miller RJH, Sharir T, Commandeur F, Rios R, Einstein AJ, Fish MB, Ruddy TD, Kaufmann PA, Sinusas AJ, Miller EJ, Bateman TM, Dorbala S, Di Carli M, Liang JX, Eisenberg E, Dey D, Berman DS, Slomka PJ. Prognostically safe stress-only single-photon emission computed tomography myocardial perfusion imaging guided by machine learning: report from REFINE SPECT. European Heart Journal Cardiovascular Imaging 2021, 22: 705-714. PMID: 32533137, DOI: 10.1093/ehjci/jeaa134.
- Gerber J, Miller EJ. Optimal interpretation of Tc99m PYP in 2020: Avoiding the million-dollar mistake. Journal Of Nuclear Cardiology : Official Publication Of The American Society Of Nuclear Cardiology 2021, 28: 503-506. PMID: 33442822, DOI: 10.1007/s12350-020-02503-8.
- Azadani PN, Miller RJH, Sharir T, Diniz MA, Hu LH, Otaki Y, Gransar H, Liang JX, Eisenberg E, Einstein AJ, Fish MB, Ruddy TD, Kaufmann PA, Sinusas AJ, Miller EJ, Bateman TM, Dorbala S, Di Carli M, Tamarappoo BK, Dey D, Berman DS, Slomka PJ. Impact of Early Revascularization on Major Adverse Cardiovascular Events in Relation to Automatically Quantified Ischemia. JACC. Cardiovascular Imaging 2021, 14: 644-653. PMID: 32828784, PMCID: PMC7987223, DOI: 10.1016/j.jcmg.2020.05.039.
- Rosenfeld LE, Chung MK, Harding CV, Spagnolo P, Grunewald J, Appelbaum J, Sauer WH, Culver DA, Joglar JA, Lin BA, Jellis CL, Dickfeld TM, Kwon DH, Miller EJ, Cremer PC, Bogun F, Kron J, Bock A, Mehta D, Leis P, Siontis KC, Kaufman ES, Crawford T, Zimetbaum P, Zishiri ET, Singh JP, Ellenbogen KA, Chrispin J, Quadri S, Vincent LL, Patton KK, Kalbfleish S, Callahan TD, Murgatroyd F, Judson MA, Birnie D, Okada DR, Maulion C, Bhat P, Bellumkonda L, Blankstein R, Cheng RK, Farr MA, Estep JD. Arrhythmias in Cardiac Sarcoidosis Bench to Bedside: A Case-Based Review. Circulation. Arrhythmia And Electrophysiology 2021, 14: e009203. PMID: 33591816, PMCID: PMC8142901, DOI: 10.1161/CIRCEP.120.009203.
- Torkaman M, Yang J, Shi L, Wang R, Miller EJ, Sinusas AJ, Liu C, Gullberg GT, Seo Y. Direct Image-Based Attenuation Correction using Conditional Generative Adversarial Network for SPECT Myocardial Perfusion Imaging. Proceedings Of SPIE--the International Society For Optical Engineering 2021, 11600 PMID: 33727759, PMCID: PMC7956874, DOI: 10.1117/12.2580922.
- Higgins AY, Annapureddy AR, Wang Y, Minges KE, Lampert R, Rosenfeld LE, Jacoby DL, Curtis JP, Miller EJ, Freeman JV. Survival Following Implantable Cardioverter-Defibrillator Implantation in Patients With Amyloid Cardiomyopathy. Journal Of The American Heart Association 2020, 9: e016038. PMID: 32867553, PMCID: PMC7726970, DOI: 10.1161/JAHA.120.016038.
- Hu LH, Sharir T, Miller RJH, Einstein AJ, Fish MB, Ruddy TD, Dorbala S, Di Carli M, Kaufmann PA, Sinusas AJ, Miller EJ, Bateman TM, Betancur J, Germano G, Liang JX, Commandeur F, Azadani PN, Gransar H, Otaki Y, Tamarappoo BK, Dey D, Berman DS, Slomka PJ. Upper reference limits of transient ischemic dilation ratio for different protocols on new-generation cadmium zinc telluride cameras: A report from REFINE SPECT registry. Journal Of Nuclear Cardiology : Official Publication Of The American Society Of Nuclear Cardiology 2020, 27: 1180-1189. PMID: 31087268, PMCID: PMC6851400, DOI: 10.1007/s12350-019-01730-y.
- Hindle-Katel W, Oen-Hsiao J, Lussnig E, Miller EJ. Incidental finding of COVID-19 pulmonary infiltrates on SPECT/CT attenuation correction CT. Journal Of Nuclear Cardiology : Official Publication Of The American Society Of Nuclear Cardiology 2020, 27: 1385-1386. PMID: 32394407, PMCID: PMC7213942, DOI: 10.1007/s12350-020-02178-1.
- Murthy VL, Bateman TM, Chen W, Malhotra S, Miller EJ, Ruddy TD, Dilsizian V. Impact of the ISCHEMIA Trial on Stress Nuclear Myocardial Perfusion Imaging. Journal Of Nuclear Medicine : Official Publication, Society Of Nuclear Medicine 2020, 61: 962-964. PMID: 32611712, PMCID: PMC7383082, DOI: 10.2967/jnumed.119.245399.
- Murthy VL, Bateman TM, Chen W, Malhotra S, Miller E, Ruddy T, Dilsizian V. Impact of the ISCHEMIA Trial on Stress Nuclear Myocardial Perfusion Imaging. Journal Of Nuclear Medicine : Official Publication, Society Of Nuclear Medicine 2020 PMID: 32513904, DOI: 10.2967/jnumed.120.245399.
- Slomka PJ, Betancur J, Liang JX, Otaki Y, Hu LH, Sharir T, Dorbala S, Di Carli M, Fish MB, Ruddy TD, Bateman TM, Einstein AJ, Kaufmann PA, Miller EJ, Sinusas AJ, Azadani PN, Gransar H, Tamarappoo BK, Dey D, Berman DS, Germano G. Rationale and design of the REgistry of Fast Myocardial Perfusion Imaging with NExt generation SPECT (REFINE SPECT). Journal Of Nuclear Cardiology : Official Publication Of The American Society Of Nuclear Cardiology 2020, 27: 1010-1021. PMID: 29923104, PMCID: PMC6301135, DOI: 10.1007/s12350-018-1326-4.
- Gallegos C, Miller EJ. Advances in PET-Based Cardiac Amyloid Radiotracers. Current Cardiology Reports 2020, 22: 40. PMID: 32430600, DOI: 10.1007/s11886-020-01284-3.
- Miller RJH, Hu LH, Gransar H, Betancur J, Eisenberg E, Otaki Y, Sharir T, Fish MB, Ruddy TD, Dorbala S, Carli MD, Einstein AJ, Kaufmann PA, Sinusas AJ, Miller EJ, Bateman T, Germano G, Tamarappoo BK, Dey D, Berman DS, Slomka PJ. Transient ischaemic dilation and post-stress wall motion abnormality increase risk in patients with less than moderate ischaemia: analysis of the REFINE SPECT registry. European Heart Journal Cardiovascular Imaging 2020, 21: 567-575. PMID: 31302679, PMCID: PMC7167750, DOI: 10.1093/ehjci/jez172.
- Hu LH, Betancur J, Sharir T, Einstein AJ, Bokhari S, Fish MB, Ruddy TD, Kaufmann PA, Sinusas AJ, Miller EJ, Bateman TM, Dorbala S, Di Carli M, Germano G, Commandeur F, Liang JX, Otaki Y, Tamarappoo BK, Dey D, Berman DS, Slomka PJ. Machine learning predicts per-vessel early coronary revascularization after fast myocardial perfusion SPECT: results from multicentre REFINE SPECT registry. European Heart Journal Cardiovascular Imaging 2020, 21: 549-559. PMID: 31317178, PMCID: PMC7167744, DOI: 10.1093/ehjci/jez177.
- Sharp MB, Soufer A, Abdelmessih M, Rosenfeld LE, Baldassarre LA, Miller EJ. Using FDG-PET to guide targeted cardiac magnetic resonance imaging in patients with suspected cardiac sarcoidosis. Journal Of Nuclear Cardiology : Official Publication Of The American Society Of Nuclear Cardiology 2020, 27: 688-690. PMID: 30737635, DOI: 10.1007/s12350-019-01640-z.
- Dorbala S, Ando Y, Bokhari S, Dispenzieri A, Falk RH, Ferrari VA, Fontana M, Gheysens O, Gillmore JD, Glaudemans AWJM, Hanna MA, Hazenberg BPC, Kristen AV, Kwong RY, Maurer MS, Merlini G, Miller EJ, Moon JC, Murthy VL, Quarta CC, Rapezzi C, Ruberg FL, Shah SJ, Slart RHJA, Verberne HJ, Bourque JM. ASNC/AHA/ASE/EANM/HFSA/ISA/SCMR/SNMMI expert consensus recommendations for multimodality imaging in cardiac amyloidosis: Part 2 of 2-Diagnostic criteria and appropriate utilization. Journal Of Nuclear Cardiology : Official Publication Of The American Society Of Nuclear Cardiology 2020, 27: 659-673. PMID: 31468377, DOI: 10.1007/s12350-019-01761-5.
- Miller EJ. Complex cellular physiology underlies the use of FDG-PET imaging in investigating post-infarction remodeling. Journal Of Nuclear Cardiology : Official Publication Of The American Society Of Nuclear Cardiology 2020, 27: 532-533. PMID: 31907858, DOI: 10.1007/s12350-019-02008-z.
- Otaki Y, Betancur J, Sharir T, Hu LH, Gransar H, Liang JX, Azadani PN, Einstein AJ, Fish MB, Ruddy TD, Kaufmann PA, Sinusas AJ, Miller EJ, Bateman TM, Dorbala S, Di Carli M, Tamarappoo BK, Germano G, Dey D, Berman DS, Slomka PJ. 5-Year Prognostic Value of Quantitative Versus Visual MPI in Subtle Perfusion Defects: Results From REFINE SPECT. JACC. Cardiovascular Imaging 2020, 13: 774-785. PMID: 31202740, PMCID: PMC6899217, DOI: 10.1016/j.jcmg.2019.02.028.
- Han D, Rozanski A, Gransar H, Sharir T, Einstein AJ, Fish MB, Ruddy TD, Kaufmann PA, Sinusas AJ, Miller EJ, Bateman TM, Dorbala S, Di Carli M, Liang JX, Hu LH, Germano G, Dey D, Berman DS, Slomka PJ. Myocardial Ischemic Burden and Differences in Prognosis Among Patients With and Without Diabetes: Results From the Multicenter International REFINE SPECT Registry. Diabetes Care 2020, 43: 453-459. PMID: 31776140, PMCID: PMC6971784, DOI: 10.2337/dc19-1360.
- Damsky W, Young BD, Sloan B, Miller EJ, Obando JA, King B. Treatment of Multiorgan Sarcoidosis With Tofacitinib. ACR Open Rheumatology 2020, 2: 106-109. PMID: 31916703, PMCID: PMC7011417, DOI: 10.1002/acr2.11112.
- Feher A, Srivastava A, Quail MA, Boutagy NE, Khanna P, Wilson L, Miller EJ, Liu YH, Lee F, Sinusas AJ. Serial Assessment of Coronary Flow Reserve by Rubidium-82 Positron Emission Tomography Predicts Mortality in Heart Transplant Recipients. JACC. Cardiovascular Imaging 2020, 13: 109-120. PMID: 30343093, PMCID: PMC6461525, DOI: 10.1016/j.jcmg.2018.08.025.
- Dorbala S, Ando Y, Bokhari S, Dispenzieri A, Falk RH, Ferrari VA, Fontana M, Gheysens O, Gillmore JD, Glaudemans AWJM, Hanna MA, Hazenberg BPC, Kristen AV, Kwong RY, Maurer MS, Merlini G, Miller EJ, Moon JC, Murthy VL, Quarta CC, Rapezzi C, Ruberg FL, Shah SJ, Slart RHJA, Verberne HJ, Bourque JM. ASNC/AHA/ASE/EANM/HFSA/ISA/SCMR/SNMMI expert consensus recommendations for multimodality imaging in cardiac amyloidosis: Part 1 of 2-evidence base and standardized methods of imaging. Journal Of Nuclear Cardiology : Official Publication Of The American Society Of Nuclear Cardiology 2019, 26: 2065-2123. PMID: 31468376, DOI: 10.1007/s12350-019-01760-6.
- Dorbala S, Ando Y, Bokhari S, Dispenzieri A, Falk RH, Ferrari VA, Fontana M, Gheysens O, Gillmore JD, Glaudemans AWJM, Hanna MA, Hazenberg BPC, Kristen AV, Kwong RY, Maurer MS, Merlini G, Miller EJ, Moon JC, Murthy VL, Quarta CC, Rapezzi C, Ruberg FL, Shah SJ, Slart RHJA, Verberne HJ, Bourque JM. ASNC/AHA/ASE/EANM/HFSA/ISA/SCMR/SNMMI Expert Consensus Recommendations for Multimodality Imaging in Cardiac Amyloidosis: Part 1 of 2-Evidence Base and Standardized Methods of Imaging. Journal Of Cardiac Failure 2019, 25: e1-e39. PMID: 31473268, DOI: 10.1016/j.cardfail.2019.08.001.
- Dorbala S, Ando Y, Bokhari S, Dispenzieri A, Falk RH, Ferrari VA, Fontana M, Gheysens O, Gillmore JD, Glaudemans AWJM, Hanna MA, Hazenberg BPC, Kristen AV, Kwong RY, Maurer MS, Merlini G, Miller EJ, Moon JC, Murthy VL, Quarta CC, Rapezzi C, Ruberg FL, Shah SJ, Slart RHJA, Verberne HJ, Bourque JM. ASNC/AHA/ASE/EANM/HFSA/ISA/SCMR/SNMMI Expert Consensus Recommendations for Multimodality Imaging in Cardiac Amyloidosis: Part 2 of 2-Diagnostic Criteria and Appropriate Utilization. Journal Of Cardiac Failure 2019, 25: 854-865. PMID: 31473267, DOI: 10.1016/j.cardfail.2019.08.002.
- Alvi RM, Young BD, Shahab Z, Pan H, Winkler J, Herzog E, Miller EJ. Repeatability and Optimization of FDG Positron Emission Tomography for Evaluation of Cardiac Sarcoidosis. JACC. Cardiovascular Imaging 2019, 12: 1284-1287. PMID: 30846271, DOI: 10.1016/j.jcmg.2019.01.011.
- Miller EJ, Jacoby D. Advanced Cardiac Imaging and the Complexity of Diagnosing Cardiac Sarcoidosis. Circulation. Cardiovascular Imaging 2019, 12: e009275. PMID: 31177819, DOI: 10.1161/CIRCIMAGING.119.009275.
- Betancur JA, Hu LH, Commandeur F, Sharir T, Einstein AJ, Fish MB, Ruddy TD, Kaufmann P, Sinusas AJ, Miller EJ, Bateman TM, Dorbala S, Di Carli M, Germano G, Otaki Y, Liang JX, Tamarappoo BK, Dey D, Berman DS, Slomka PJ. Deep Learning Analysis of Upright-Supine High-Efficiency SPECT Myocardial Perfusion Imaging for Prediction of Obstructive Coronary Artery Disease: A Multicenter Study. Journal Of Nuclear Medicine : Official Publication, Society Of Nuclear Medicine 2019, 60: 664-670. PMID: 30262516, PMCID: PMC6495237, DOI: 10.2967/jnumed.118.213538.
- Chen K, Miller EJ, Sadeghi MM. PET-Based Imaging of Ischemic Heart Disease. PET Clinics 2019, 14: 211-221. PMID: 30826019, PMCID: PMC6426655, DOI: 10.1016/j.cpet.2018.12.003.
- Betancur J, Commandeur F, Motlagh M, Sharir T, Einstein AJ, Bokhari S, Fish MB, Ruddy TD, Kaufmann P, Sinusas AJ, Miller EJ, Bateman TM, Dorbala S, Di Carli M, Germano G, Otaki Y, Tamarappoo BK, Dey D, Berman DS, Slomka PJ. Deep Learning for Prediction of Obstructive Disease From Fast Myocardial Perfusion SPECT: A Multicenter Study. JACC. Cardiovascular Imaging 2018, 11: 1654-1663. PMID: 29550305, PMCID: PMC6135711, DOI: 10.1016/j.jcmg.2018.01.020.
- Gallegos C, Miller EJ. Use of fluorine-18 sodium fluoride for the diagnosis of transthyretin cardiac amyloidosis: The birth of a new technique. Journal Of Nuclear Cardiology : Official Publication Of The American Society Of Nuclear Cardiology 2018, 25: 1568-1570. PMID: 28357811, DOI: 10.1007/s12350-017-0847-6.
- Higgins AY, Taylor EP, Baldassarre LA, Miller EJ, Rosenfeld LE. Diagnosis of extensive myocardial infiltration by diffuse large B-cell lymphoma using 18F-fluorodeoxyglucose positron emission tomography (18-FDG PET). Journal Of Nuclear Cardiology : Official Publication Of The American Society Of Nuclear Cardiology 2018, 25: 1869-1871. PMID: 29116563, DOI: 10.1007/s12350-017-1099-1.
- Boutagy NE, Wu J, Cai Z, Zhang W, Booth CJ, Kyriakides TC, Pfau D, Mulnix T, Liu Z, Miller EJ, Young LH, Carson RE, Huang Y, Liu C, Sinusas AJ. In Vivo Reactive Oxygen Species Detection With a Novel Positron Emission Tomography Tracer, 18F-DHMT, Allows for Early Detection of Anthracycline-Induced Cardiotoxicity in Rodents. JACC. Basic To Translational Science 2018, 3: 378-390. PMID: 30062224, PMCID: PMC6058999, DOI: 10.1016/j.jacbts.2018.02.003.
- Alvi R, Miller EJ, Hashemi Zonouz T, Sandoval V, Tariq N, Lampert R, Sinusas AJ, Liu YH. Quantification and Determination of Normal 123I-Meta Iodobenzylguanidine Heart-to-Mediastinum Ratio (HMR) from Cardiac SPECT/CT and Correlation with Planar HMR. Journal Of Nuclear Medicine : Official Publication, Society Of Nuclear Medicine 2018, 59: 652-658. PMID: 28916622, DOI: 10.2967/jnumed.117.197152.
- Slart RHJA, Glaudemans AWJM, Lancellotti P, Hyafil F, Blankstein R, Schwartz RG, Jaber WA, Russell R, Gimelli A, Rouzet F, Hacker M, Gheysens O, Plein S, Miller EJ, Dorbala S, Donal E. A joint procedural position statement on imaging in cardiac sarcoidosis: from the Cardiovascular and Inflammation & Infection Committees of the European Association of Nuclear Medicine, the European Association of Cardiovascular Imaging, and the American Society of Nuclear Cardiology. Journal Of Nuclear Cardiology : Official Publication Of The American Society Of Nuclear Cardiology 2018, 25: 298-319. PMID: 29043557, DOI: 10.1007/s12350-017-1043-4.
- Papoutsidakis N, Miller EJ, Rodonski A, Jacoby D. Time Course of Common Clinical Manifestations in Patients with Transthyretin Cardiac Amyloidosis: Delay From Symptom Onset to Diagnosis. Journal Of Cardiac Failure 2018, 24: 131-133. PMID: 29305186, DOI: 10.1016/j.cardfail.2017.12.005.
- Miller EJ, Culver DA. Establishing an Evidence-Based Method to Diagnose Cardiac Sarcoidosis: The Complementary Use of Cardiac Magnetic Resonance Imaging and FDG-PET. Circulation. Cardiovascular Imaging 2018, 11: e007408. PMID: 29335273, DOI: 10.1161/CIRCIMAGING.117.007408.
- Varghese M, Smiley D, Bellumkonda L, Rosenfeld LE, Lavanya B, Miller EJ. Quantitative interpretation of FDG PET for cardiac sarcoidosis reclassifies visually interpreted exams and potentially impacts downstream interventions. Sarcoidosis, Vasculitis, And Diffuse Lung Diseases : Official Journal Of WASOG / World Association Of Sarcoidosis And Other Granulomatous Disorders 2018, 35: 342-353. PMID: 32476922, PMCID: PMC7170132, DOI: 10.36141/svdld.v35i4.7342.
- Chareonthaitawee P, Beanlands RS, Chen W, Dorbala S, Miller EJ, Murthy VL, Birnie DH, Chen ES, Cooper LT, Tung RH, White ES, Borges-Neto S, Di Carli MF, Gropler RJ, Ruddy TD, Schindler TH, Blankstein R. Joint SNMMI-ASNC expert consensus document on the role of 18F-FDG PET/CT in cardiac sarcoid detection and therapy monitoring. Journal Of Nuclear Cardiology : Official Publication Of The American Society Of Nuclear Cardiology 2017, 24: 1741-1758. PMID: 28770463, DOI: 10.1007/s12350-017-0978-9.
- Salinaro F, Meier-Ewert HK, Miller EJ, Pandey S, Sanchorawala V, Berk JL, Seldin DC, Ruberg FL. Longitudinal systolic strain, cardiac function improvement, and survival following treatment of light-chain (AL) cardiac amyloidosis. European Heart Journal Cardiovascular Imaging 2017, 18: 1057-1064. PMID: 27965280, DOI: 10.1093/ehjci/jew298.
- Chareonthaitawee P, Beanlands RS, Chen W, Dorbala S, Miller EJ, Murthy VL, Birnie DH, Chen ES, Cooper LT, Tung RH, White ES, Borges-Neto S, Di Carli MF, Gropler RJ, Ruddy TD, Schindler TH, Blankstein R. Joint SNMMI-ASNC Expert Consensus Document on the Role of 18F-FDG PET/CT in Cardiac Sarcoid Detection and Therapy Monitoring. Journal Of Nuclear Medicine : Official Publication, Society Of Nuclear Medicine 2017, 58: 1341-1353. PMID: 28765228, PMCID: PMC6944184, DOI: 10.2967/jnumed.117.196287.
- Harb SC, Haq M, Flood K, Guerrieri A, Passerell W, Jaber WA, Miller EJ. National patterns in imaging utilization for diagnosis of cardiac amyloidosis: A focus on Tc99m-pyrophosphate scintigraphy. Journal Of Nuclear Cardiology : Official Publication Of The American Society Of Nuclear Cardiology 2017, 24: 1094-1097. PMID: 27016106, DOI: 10.1007/s12350-016-0478-3.
- Morse JC, Huang J, Khona N, Miller EJ, Siwik DA, Colucci WS, Hobai IA. Up-regulation of Intracellular Calcium Handling Underlies the Recovery of Endotoxemic Cardiomyopathy in Mice. Anesthesiology 2017, 126: 1125-1138. PMID: 28410273, DOI: 10.1097/ALN.0000000000001627.
- Haq M, Pawar S, Berk JL, Miller EJ, Ruberg FL. Can 99mTc-Pyrophosphate Aid in Early Detection of Cardiac Involvement in Asymptomatic Variant TTR Amyloidosis? JACC. Cardiovascular Imaging 2017, 10: 713-714. PMID: 27568122, PMCID: PMC5318295, DOI: 10.1016/j.jcmg.2016.06.003.
- Patchett ND, Pawar S, Miller EJ. Visual identification of coronary calcifications on attenuation correction CT improves diagnostic accuracy of SPECT/CT myocardial perfusion imaging. Journal Of Nuclear Cardiology : Official Publication Of The American Society Of Nuclear Cardiology 2017, 24: 711-720. PMID: 26850031, DOI: 10.1007/s12350-016-0395-5.
- Ahmadian A, Pawar S, Govender P, Berman J, Ruberg FL, Miller EJ. The response of FDG uptake to immunosuppressive treatment on FDG PET/CT imaging for cardiac sarcoidosis. Journal Of Nuclear Cardiology : Official Publication Of The American Society Of Nuclear Cardiology 2017, 24: 413-424. PMID: 27457527, DOI: 10.1007/s12350-016-0490-7.
- Blankstein R, Miller EJ. Quantifying FDG uptake to diagnose cardiac device infections: When and how should we do it? Journal Of Nuclear Cardiology : Official Publication Of The American Society Of Nuclear Cardiology 2016, 23: 1467-1469. PMID: 26494648, DOI: 10.1007/s12350-015-0293-2.
- Castano A, Haq M, Narotsky DL, Goldsmith J, Weinberg RL, Morgenstern R, Pozniakoff T, Ruberg FL, Miller EJ, Berk JL, Dispenzieri A, Grogan M, Johnson G, Bokhari S, Maurer MS. Multicenter Study of Planar Technetium 99m Pyrophosphate Cardiac Imaging: Predicting Survival for Patients With ATTR Cardiac Amyloidosis. JAMA Cardiology 2016, 1: 880-889. PMID: 27557400, DOI: 10.1001/jamacardio.2016.2839.
- Gillmore JD, Maurer MS, Falk RH, Merlini G, Damy T, Dispenzieri A, Wechalekar AD, Berk JL, Quarta CC, Grogan M, Lachmann HJ, Bokhari S, Castano A, Dorbala S, Johnson GB, Glaudemans AW, Rezk T, Fontana M, Palladini G, Milani P, Guidalotti PL, Flatman K, Lane T, Vonberg FW, Whelan CJ, Moon JC, Ruberg FL, Miller EJ, Hutt DF, Hazenberg BP, Rapezzi C, Hawkins PN. Nonbiopsy Diagnosis of Cardiac Transthyretin Amyloidosis. Circulation 2016, 133: 2404-12. PMID: 27143678, DOI: 10.1161/CIRCULATIONAHA.116.021612.
- Sverdlov AL, Elezaby A, Qin F, Behring JB, Luptak I, Calamaras TD, Siwik DA, Miller EJ, Liesa M, Shirihai OS, Pimentel DR, Cohen RA, Bachschmid MM, Colucci WS. Mitochondrial Reactive Oxygen Species Mediate Cardiac Structural, Functional, and Mitochondrial Consequences of Diet-Induced Metabolic Heart Disease. Journal Of The American Heart Association 2016, 5 PMID: 26755553, PMCID: PMC4859372, DOI: 10.1161/JAHA.115.002555.
- Miller EJ, Calamaras T, Elezaby A, Sverdlov A, Qin F, Luptak I, Wang K, Sun X, Vijay A, Croteau D, Bachschmid M, Cohen RA, Walsh K, Colucci WS. Partial Liver Kinase B1 (LKB1) Deficiency Promotes Diastolic Dysfunction, De Novo Systolic Dysfunction, Apoptosis, and Mitochondrial Dysfunction With Dietary Metabolic Challenge. Journal Of The American Heart Association 2015, 5 PMID: 26722122, PMCID: PMC4859355, DOI: 10.1161/JAHA.115.002277.
- Sung MM, Zordoky BN, Bujak AL, Lally JS, Fung D, Young ME, Horman S, Miller EJ, Light PE, Kemp BE, Steinberg GR, Dyck JR. AMPK deficiency in cardiac muscle results in dilated cardiomyopathy in the absence of changes in energy metabolism. Cardiovascular Research 2015, 107: 235-45. PMID: 26023060, PMCID: PMC4565988, DOI: 10.1093/cvr/cvv166.
- Elezaby A, Sverdlov AL, Tu VH, Soni K, Luptak I, Qin F, Liesa M, Shirihai OS, Rimer J, Schaffer JE, Colucci WS, Miller EJ. Mitochondrial remodeling in mice with cardiomyocyte-specific lipid overload. Journal Of Molecular And Cellular Cardiology 2015, 79: 275-83. PMID: 25497302, PMCID: PMC4301992, DOI: 10.1016/j.yjmcc.2014.12.001.
- Sverdlov AL, Elezaby A, Behring JB, Bachschmid MM, Luptak I, Tu VH, Siwik DA, Miller EJ, Liesa M, Shirihai OS, Pimentel DR, Cohen RA, Colucci WS. High fat, high sucrose diet causes cardiac mitochondrial dysfunction due in part to oxidative post-translational modification of mitochondrial complex II. Journal Of Molecular And Cellular Cardiology 2015, 78: 165-73. PMID: 25109264, PMCID: PMC4268348, DOI: 10.1016/j.yjmcc.2014.07.018.
- Ahmadian A, Brogan A, Berman J, Sverdlov AL, Mercier G, Mazzini M, Govender P, Ruberg FL, Miller EJ. Quantitative interpretation of FDG PET/CT with myocardial perfusion imaging increases diagnostic information in the evaluation of cardiac sarcoidosis. Journal Of Nuclear Cardiology : Official Publication Of The American Society Of Nuclear Cardiology 2014, 21: 925-39. PMID: 24879453, DOI: 10.1007/s12350-014-9901-9.
- Ayalon N, Gopal DM, Mooney DM, Simonetti JS, Grossman JR, Dwivedi A, Donohue C, Perez AJ, Downing J, Gokce N, Miller EJ, Liang CS, Apovian CM, Colucci WS, Ho JE. Preclinical left ventricular diastolic dysfunction in metabolic syndrome. The American Journal Of Cardiology 2014, 114: 838-42. PMID: 25084691, PMCID: PMC4162746, DOI: 10.1016/j.amjcard.2014.06.013.
- Berman JS, Govender P, Ruberg FL, Mazzini M, Miller EJ. Scadding revisited: a proposed staging system for cardiac sarcoidosis. Sarcoidosis, Vasculitis, And Diffuse Lung Diseases : Official Journal Of WASOG / World Association Of Sarcoidosis And Other Granulomatous Disorders 2014, 31: 2-5. PMID: 24751447.
- Li J, Qi D, Cheng H, Hu X, Miller EJ, Wu X, Russell KS, Mikush N, Zhang J, Xiao L, Sherwin RS, Young LH. Urocortin 2 autocrine/paracrine and pharmacologic effects to activate AMP-activated protein kinase in the heart. Proceedings Of The National Academy Of Sciences Of The United States Of America 2013, 110: 16133-8. PMID: 24043794, PMCID: PMC3791748, DOI: 10.1073/pnas.1312775110.
- Ruberg FL, Miller EJ. Nuclear tracers for transthyretin cardiac amyloidosis: time to bone up? Circulation. Cardiovascular Imaging 2013, 6: 162-4. PMID: 23512778, DOI: 10.1161/CIRCIMAGING.113.000178.
- Qin F, Siwik DA, Luptak I, Hou X, Wang L, Higuchi A, Weisbrod RM, Ouchi N, Tu VH, Calamaras TD, Miller EJ, Verbeuren TJ, Walsh K, Cohen RA, Colucci WS. The polyphenols resveratrol and S17834 prevent the structural and functional sequelae of diet-induced metabolic heart disease in mice. Circulation 2012, 125: 1757-64, S1-6. PMID: 22388319, PMCID: PMC3354628, DOI: 10.1161/CIRCULATIONAHA.111.067801.
- Depuey EG, Mahmarian JJ, Miller TD, Einstein AJ, Hansen CL, Holly TA, Miller EJ, Polk DM, Samuel Wann L. Patient-centered imaging. Journal Of Nuclear Cardiology : Official Publication Of The American Society Of Nuclear Cardiology 2012, 19: 185-215. PMID: 22328324, DOI: 10.1007/s12350-012-9523-z.
- Russell RR, Abbott BG, Arrighi JA, Blankstein R, Faber TL, Mahmarian JJ, Miller EJ, Miller TD, Shaw LJ, Soman P, Travin MI. Highlights of the 2011 Scientific Session of the American Society of Nuclear Cardiology: Denver, Colorado, September 8-11, 2011. Journal Of Nuclear Cardiology : Official Publication Of The American Society Of Nuclear Cardiology 2012, 19: 158-64. PMID: 22071955, DOI: 10.1007/s12350-011-9479-4.
- Kim AS, Miller EJ, Wright TM, Li J, Qi D, Atsina K, Zaha V, Sakamoto K, Young LH. A small molecule AMPK activator protects the heart against ischemia-reperfusion injury. Journal Of Molecular And Cellular Cardiology 2011, 51: 24-32. PMID: 21402077, PMCID: PMC4005884, DOI: 10.1016/j.yjmcc.2011.03.003.
- Amundson D, Dadekian G, Etienne M, Gleeson T, Hicks T, Killian D, Kratovil K, Lewis C, Monsour M, Pasiuk B, Rhodes D, Miller EJ. Practicing internal medicine onboard the USNS COMFORT in the aftermath of the Haitian earthquake. Annals Of Internal Medicine 2010, 152: 733-7. PMID: 20197507, DOI: 10.7326/0003-4819-152-11-201006010-00215.
- Kim AS, Miller EJ, Young LH. AMP-activated protein kinase: a core signalling pathway in the heart. Acta Physiologica (Oxford, England) 2009, 196: 37-53. PMID: 19239414, DOI: 10.1111/j.1748-1716.2009.01978.x.
- Ozcan C, Miller EJ, Russell KS, Dewar ML, Rosenfeld LE. An unusual case of nonbacterial thrombotic (marantic) endocarditis. The Journal Of Thoracic And Cardiovascular Surgery 2009, 137: 239-41. PMID: 19154931, DOI: 10.1016/j.jtcvs.2008.01.019.
- Miller EJ, Li J, Leng L, McDonald C, Atsumi T, Bucala R, Young LH. Macrophage migration inhibitory factor stimulates AMP-activated protein kinase in the ischaemic heart. Nature 2008, 451: 578-82. PMID: 18235500, DOI: 10.1038/nature06504.
- Miller EJ, Li J, Sinusas KM, Holman GD, Young LH. Infusion of a biotinylated bis-glucose photolabel: a new method to quantify cell surface GLUT4 in the intact mouse heart. American Journal Of Physiology. Endocrinology And Metabolism 2007, 292: E1922-8. PMID: 17341550, DOI: 10.1152/ajpendo.00170.2006.
- Li J, Coven DL, Miller EJ, Hu X, Young ME, Carling D, Sinusas AJ, Young LH. Activation of AMPK alpha- and gamma-isoform complexes in the intact ischemic rat heart. American Journal Of Physiology. Heart And Circulatory Physiology 2006, 291: H1927-34. PMID: 16648175, DOI: 10.1152/ajpheart.00251.2006.
- Li J, Miller EJ, Ninomiya-Tsuji J, Russell RR, Young LH. AMP-activated protein kinase activates p38 mitogen-activated protein kinase by increasing recruitment of p38 MAPK to TAB1 in the ischemic heart. Circulation Research 2005, 97: 872-9. PMID: 16179588, DOI: 10.1161/01.RES.0000187458.77026.10.
- Baron SJ, Li J, Russell RR, Neumann D, Miller EJ, Tuerk R, Wallimann T, Hurley RL, Witters LA, Young LH. Dual mechanisms regulating AMPK kinase action in the ischemic heart. Circulation Research 2005, 96: 337-45. PMID: 15653571, DOI: 10.1161/01.RES.0000155723.53868.d2.
- Miller EJ. Doctors and torture. The New England Journal Of Medicine 2004, 351: 1571-4; author reply 1571-4. PMID: 15473022.
- Yale Physicians Building800 Howard Avenue, Fl 2ndNew Haven, CT 06519
Biography
Edward J. Miller, MD, PhD, treats chronic heart including infiltrative cardiomyopathies. “The Yale Medicine Cardiomyopathy Inherited Cardiovascular Disease Program has a wonderful interdisciplinary team of experts in the diagnosis and management of infiltrative cardiomyopathies,” says Dr. Miller, who also directs the clinical nuclear cardiology laboratory at Yale New Haven Hospital
An expert at using imaging to diagnose and treat heart disease, Dr. Miller is especially interested in the use of new imaging techniques in cardiac sarcoidosis (an inflammatory disorder) and cardiac amyloidosis (a disorder of protein deposits). He is also focused on the role of obesity in certain types of heart disease.
Dr. Miller is an assistant professor of medicine, and of radiology and biomedical imaging at Yale School of Medicine.
Titles
- Associate Professor of Medicine (Cardiovascular Medicine)
- Vice Chief of Cardiovascular Medicine (Education), Cardiovascular Medicine
- Associate Professor of Medicine and Radiology
- Director, Nuclear Cardiology, Cardiovascular Medicine
- Director, Cardiology Fellowship Program, Cardiovascular Medicine
Education & Training
- Clinical FellowYale School of Medicine (2008)
- PhDYale University School of Medicine, Investigative Medicine (2008)
- Research FellowYale School of Medicine (2005)
- ResidentYale-New Haven Hospital (2003)
- InternYale-New Haven Hospital (2000)
- MDLoyola-Stritch School of Medicine, Medicine (1999)
- BSUniversity of Notre Dame, Preprofessional Studies (1994)
Additional Information
- Fellow, American College of Cardiology: American College of Cardiology (2017)
- Fellow, American Society of Nuclear Cardiology: American Society of Nuclear Cardiology (2014)
- Navy and Marine Corps Commendation Medal: United States Navy (2001)
- Navy Combat Action Ribbon: United States Navy (2001)
- Alpha Omega Alpha: (1999)
- Society of Nuclear Medicine and Molecular Imaging - Cardiovascular Council (2015 - Present): Board of Directors
- Certification Board of Nuclear Cardiology (2013 - Present): Board of Directors
- American Society of Nuclear Cardiology (2009 - 2010): Leadership Development Program
- Al-Mallah MH, Bateman TM, Branch KR, Crean A, Gingold EL, Thompson RC, McKenney SE, Miller EJ, Murthy VL, Nieman K, Villines TC, Yester MV, Einstein AJ, Mahmarian JJ. 2022 ASNC/AAPM/SCCT/SNMMI guideline for the use of CT in hybrid nuclear/CT cardiac imaging. Journal Of Nuclear Cardiology : Official Publication Of The American Society Of Nuclear Cardiology 2022 PMID: 36056224, DOI: 10.1007/s12350-022-03089-z.
- Chen X, Zhou B, Xie H, Miao T, Liu H, Holler W, Lin M, Miller EJ, Carson RE, Sinusas AJ, Liu C. DuDoSS: Deep-Learning-Based Dual-Domain sinogram synthesis from Sparsely-sampled projections of cardiac SPECT. Medical Physics 2022 PMID: 36048541, DOI: 10.1002/mp.15958.
- Sperry BW, Bateman TM, Akin EA, Bravo PE, Chen W, Dilsizian V, Hyafil F, Khor YM, Miller RJH, Slart RHJA, Slomka P, Verberne H, Miller EJ, Liu C. Hot spot imaging in cardiovascular diseases: an information statement from SNMMI, ASNC, and EANM. Journal Of Nuclear Cardiology : Official Publication Of The American Society Of Nuclear Cardiology 2022 PMID: 35864433, DOI: 10.1007/s12350-022-02985-8.
- Sperry BW, Bateman TM, Akin EA, Bravo PE, Chen W, Dilsizian V, Hyafil F, Khor YM, Miller RJH, Slart RHJA, Slomka P, Verberne H, Miller EJ, Liu C. Hot Spot Imaging in Cardiovascular Diseases: An Information Statement from SNMMI, ASNC, and EANM. Journal Of Nuclear Medicine : Official Publication, Society Of Nuclear Medicine 2022 PMID: 35863895, DOI: 10.2967/jnumed.122.264311.
- Rios R, Miller RJH, Hu LH, Otaki Y, Singh A, Diniz M, Sharir T, Einstein AJ, Fish MB, Ruddy TD, Kaufmann PA, Sinusas AJ, Miller EJ, Bateman TM, Dorbala S, DiCarli M, Van Kriekinge S, Kavanagh P, Parekh T, Liang JX, Dey D, Berman DS, Slomka P. Determining a minimum set of variables for machine learning cardiovascular event prediction: results from REFINE SPECT registry. Cardiovascular Research 2022, 118: 2152-2164. PMID: 34259870, PMCID: PMC9302886, DOI: 10.1093/cvr/cvab236.
- Miller EJ, Campisi R, Shah NR, McMahon S, Cuddy S, Gallegos-Kattan C, Maurer MS, Damy T, Slart RHJA, Bhatia K, Einstein AJ. Radiopharmaceutical supply disruptions and the use of 99mTc-hydroxymethylene diphosphonate as an alternative to 99mTc-pyrophosphate for the diagnosis of transthyretin cardiac amyloidosis: An ASNC Information Statement. Journal Of Nuclear Cardiology : Official Publication Of The American Society Of Nuclear Cardiology 2022 PMID: 35838892, PMCID: PMC9285188, DOI: 10.1007/s12350-022-03059-5.
- Dorbala S, Ando Y, Bokhari S, Dispenzieri A, Falk RH, Ferrari VA, Fontana M, Gheysens O, Gillmore JD, Glaudemans AWJM, Hanna MA, Hazenberg BPC, Kristen AV, Kwong RY, Maurer MS, Merlini G, Miller EJ, Moon JC, Murthy VL, Quarta CC, Rapezzi C, Ruberg FL, Shah SJ, Slart RHJA, Verberne HJ, Bourque JM. Addendum to ASNC/AHA/ASE/EANM/HFSA/ISA/SCMR/SNMMI Expert Consensus Recommendations for Multimodality Imaging in Cardiac Amyloidosis: Part 1 of 2-Evidence Base and Standardized Methods of Imaging. Journal Of Cardiac Failure 2022, 28: e1-e4. PMID: 34217819, DOI: 10.1016/j.cardfail.2021.06.012.
- Chen X, Zhou B, Xie H, Shi L, Liu H, Holler W, Lin M, Liu YH, Miller EJ, Sinusas AJ, Liu C. Direct and indirect strategies of deep-learning-based attenuation correction for general purpose and dedicated cardiac SPECT. European Journal Of Nuclear Medicine And Molecular Imaging 2022, 49: 3046-3060. PMID: 35169887, PMCID: PMC9253078, DOI: 10.1007/s00259-022-05718-8.
- Miller RJH, Hauser MT, Sharir T, Einstein AJ, Fish MB, Ruddy TD, Kaufmann PA, Sinusas AJ, Miller EJ, Bateman TM, Dorbala S, Di Carli M, Huang C, Liang JX, Han D, Dey D, Berman DS, Slomka PJ. Machine learning to predict abnormal myocardial perfusion from pre-test features. Journal Of Nuclear Cardiology : Official Publication Of The American Society Of Nuclear Cardiology 2022 PMID: 35672567, DOI: 10.1007/s12350-022-03012-6.
- Damsky W, Wang A, Kim DJ, Young BD, Singh K, Murphy MJ, Daccache J, Clark A, Ayasun R, Ryu C, McGeary MK, Odell ID, Fazzone-Chettiar R, Pucar D, Homer R, Gulati M, Miller EJ, Bosenberg M, Flavell RA, King B. Inhibition of type 1 immunity with tofacitinib is associated with marked improvement in longstanding sarcoidosis. Nature Communications 2022, 13: 3140. PMID: 35668129, PMCID: PMC9170782, DOI: 10.1038/s41467-022-30615-x.
- Otaki Y, Singh A, Kavanagh P, Miller RJH, Parekh T, Tamarappoo BK, Sharir T, Einstein AJ, Fish MB, Ruddy TD, Kaufmann PA, Sinusas AJ, Miller EJ, Bateman TM, Dorbala S, Di Carli M, Cadet S, Liang JX, Dey D, Berman DS, Slomka PJ. Clinical Deployment of Explainable Artificial Intelligence of SPECT for Diagnosis of Coronary Artery Disease. JACC. Cardiovascular Imaging 2022, 15: 1091-1102. PMID: 34274267, PMCID: PMC9020794, DOI: 10.1016/j.jcmg.2021.04.030.
- Pathak GA, De Lillo A, Wendt FR, De Angelis F, Koller D, Cabrera Mendoza B, Jacoby D, Miller EJ, Buxbaum JN, Polimanti R. The integration of genetically-regulated transcriptomics and electronic health records highlights a pattern of medical outcomes related to increased hepatic transthyretin expression. Amyloid : The International Journal Of Experimental And Clinical Investigation : The Official Journal Of The International Society Of Amyloidosis 2022, 29: 110-119. PMID: 34935565, PMCID: PMC9213571, DOI: 10.1080/13506129.2021.2018678.
- Rios R, Miller RJH, Manral N, Sharir T, Einstein AJ, Fish MB, Ruddy TD, Kaufmann PA, Sinusas AJ, Miller EJ, Bateman TM, Dorbala S, Di Carli M, Van Kriekinge SD, Kavanagh PB, Parekh T, Liang JX, Dey D, Berman DS, Slomka PJ. Handling missing values in machine learning to predict patient-specific risk of adverse cardiac events: Insights from REFINE SPECT registry. Computers In Biology And Medicine 2022, 145: 105449. PMID: 35381453, PMCID: PMC9117456, DOI: 10.1016/j.compbiomed.2022.105449.
- Tamarappoo BK, Otaki Y, Sharir T, Hu LH, Gransar H, Einstein AJ, Fish MB, Ruddy TD, Kaufmann P, Sinusas AJ, Miller EJ, Bateman TM, Dorbala S, Di Carli M, Eisenberg E, Liang JX, Dey D, Berman DS, Slomka PJ. Differences in Prognostic Value of Myocardial Perfusion Single-Photon Emission Computed Tomography Using High-Efficiency Solid-State Detector Between Men and Women in a Large International Multicenter Study. Circulation. Cardiovascular Imaging 2022, 15: e012741. PMID: 35727872, PMCID: PMC9307118, DOI: 10.1161/CIRCIMAGING.121.012741.
- Wang SY, Adejumo P, See C, Onuma OK, Miller EJ, Spatz ES. Characteristics of patients referred to a cardiovascular disease clinic for post-acute sequelae of SARS-CoV-2 infection. American Heart Journal Plus : Cardiology Research And Practice 2022, 18: 100176. PMID: 35856065, PMCID: PMC9277988, DOI: 10.1016/j.ahjo.2022.100176.
- Miller RJH, Kuronuma K, Singh A, Otaki Y, Hayes S, Chareonthaitawee P, Kavanagh P, Parekh T, Tamarappoo BK, Sharir T, Einstein AJ, Fish MB, Ruddy TD, Kaufmann PA, Sinusas AJ, Miller EJ, Bateman T, Dorbala S, Di Carli MF, Cadet S, Liang JX, Dey D, Berman DS, Slomka PJ. Explainable Deep Learning Improves Physician Interpretation of Myocardial Perfusion Imaging. Journal Of Nuclear Medicine : Official Publication, Society Of Nuclear Medicine 2022 PMID: 35512997, DOI: 10.2967/jnumed.121.263686.
- Klein E, Miller RJH, Sharir T, Einstein AJ, Fish MB, Ruddy TD, Kaufmann PA, Sinusas AJ, Miller EJ, Bateman TM, Dorbala S, Di Carli M, Otaki Y, Gransar H, Liang JX, Dey D, Berman DS, Slomka PJ. Automated quantitative analysis of CZT SPECT stratifies cardiovascular risk in the obese population: Analysis of the REFINE SPECT registry. Journal Of Nuclear Cardiology : Official Publication Of The American Society Of Nuclear Cardiology 2022, 29: 727-736. PMID: 32929639, PMCID: PMC8497048, DOI: 10.1007/s12350-020-02334-7.
- Higgins AY, Annapureddy AR, Wang Y, Minges KE, Bellumkonda L, Lampert R, Rosenfeld LE, Jacoby DL, Curtis JP, Miller EJ, Freeman JV. Risk and predictors of mortality after implantable cardioverter-defibrillator implantation in patients with sarcoid cardiomyopathy. American Heart Journal 2022, 246: 21-31. PMID: 34968442, DOI: 10.1016/j.ahj.2021.12.011.
- Han D, Rozanski A, Miller RJH, Sharir T, Einstein AJ, Fish MB, Ruddy TD, Kaufmann PA, Sinusas AJ, Miller EJ, Bateman TM, Dorbala S, Di Carli M, Liang JX, Dey D, Berman DS, Slomka PJ. Prevalence and predictors of automatically quantified myocardial ischemia within a multicenter international registry. Journal Of Nuclear Cardiology : Official Publication Of The American Society Of Nuclear Cardiology 2022 PMID: 35174442, PMCID: PMC9378748, DOI: 10.1007/s12350-021-02829-x.
- Wu J, Boutagy NE, Cai Z, Lin SF, Zheng MQ, Feher A, Stendahl JC, Kapinos M, Gallezot JD, Liu H, Mulnix T, Zhang W, Lindemann M, Teng JK, Miller EJ, Huang Y, Carson RE, Sinusas AJ, Liu C. Feasibility study of PET dynamic imaging of [18F]DHMT for quantification of reactive oxygen species in the myocardium of large animals. Journal Of Nuclear Cardiology : Official Publication Of The American Society Of Nuclear Cardiology 2022, 29: 216-225. PMID: 32415628, PMCID: PMC7666654, DOI: 10.1007/s12350-020-02184-3.
- Murray MF, Miller EJ. Can We Manage Presymptomatic TTR V142I Related Risk? JACC. Heart Failure 2022, 10: 139-141. PMID: 35115087, DOI: 10.1016/j.jchf.2021.10.009.
- Shi L, Lu Y, Dvornek N, Weyman CA, Miller EJ, Sinusas AJ, Liu C. Automatic Inter-Frame Patient Motion Correction for Dynamic Cardiac PET Using Deep Learning. IEEE Transactions On Medical Imaging 2021, 40: 3293-3304. PMID: 34018932, PMCID: PMC8670362, DOI: 10.1109/TMI.2021.3082578.
- Han D, Rozanski A, Gransar H, Tzolos E, Miller RJH, Sharir T, Einstein AJ, Fish MB, Ruddy TD, Kaufmann PA, Sinusas AJ, Miller EJ, Bateman TM, Dorbala S, Di Carli M, Liang JX, Hu LH, Dey D, Berman DS, Slomka PJ. Comparison of diabetes to other prognostic predictors among patients referred for cardiac stress testing: A contemporary analysis from the REFINE SPECT Registry. Journal Of Nuclear Cardiology : Official Publication Of The American Society Of Nuclear Cardiology 2021 PMID: 34757571, PMCID: PMC9085969, DOI: 10.1007/s12350-021-02810-8.
- Park J, Young BD, Miller EJ. Potential novel imaging targets of inflammation in cardiac sarcoidosis. Journal Of Nuclear Cardiology : Official Publication Of The American Society Of Nuclear Cardiology 2021 PMID: 34734365, DOI: 10.1007/s12350-021-02838-w.
- Yang J, Shi L, Wang R, Miller EJ, Sinusas AJ, Liu CJ, Gullberg GT, Seo Y. Direct Attenuation Correction Using Deep Learning for Cardiac SPECT: A Feasibility Study. Journal Of Nuclear Medicine : Official Publication, Society Of Nuclear Medicine 2021, 62: 1645-1652. PMID: 33637586, PMCID: PMC8612332, DOI: 10.2967/jnumed.120.256396.
- Miller RJH, Sharir T, Otaki Y, Gransar H, Liang JX, Einstein AJ, Fish MB, Ruddy TD, Kaufmann PA, Sinusas AJ, Miller EJ, Bateman TM, Dorbala S, Di Carli M, Tamarappoo BK, Dey D, Berman DS, Slomka PJ. Quantitation of Poststress Change in Ventricular Morphology Improves Risk Stratification. Journal Of Nuclear Medicine : Official Publication, Society Of Nuclear Medicine 2021, 62: 1582-1590. PMID: 33712535, PMCID: PMC8612345, DOI: 10.2967/jnumed.120.260141.
- Liu H, Wu J, Shi L, Liu Y, Miller E, Sinusas A, Liu YH, Liu C. Post-reconstruction attenuation correction for SPECT myocardium perfusion imaging facilitated by deep learning-based attenuation map generation. Journal Of Nuclear Cardiology : Official Publication Of The American Society Of Nuclear Cardiology 2021 PMID: 34671940, DOI: 10.1007/s12350-021-02817-1.
- Feher A, Boutagy NE, Oikonomou EK, Thorn S, Liu YH, Miller EJ, Sinusas AJ, Hinchcliff M. Impaired Myocardial Flow Reserve on 82Rubidium Positron Emission Tomography/Computed Tomography in Patients With Systemic Sclerosis. The Journal Of Rheumatology 2021, 48: 1574-1582. PMID: 34266986, DOI: 10.3899/jrheum.210040.
- Young BD, Moreland H, Oatmen KE, Freeburg LA, Shahab Z, Herzog E, Miller EJ, Spinale FG. Cytokine Signaling and Matrix Remodeling Pathways Associated with Cardiac Sarcoidosis Disease Activity Defined Using FDG PET Imaging. International Heart Journal 2021, 62: 1096-1105. PMID: 34544982, DOI: 10.1536/ihj.21-164.
- Wendt FR, Koller D, Pathak GA, Jacoby D, Miller EJ, Polimanti R. Biobank Scale Pharmacogenomics Informs the Genetic Underpinnings of Simvastatin Use. Clinical Pharmacology And Therapeutics 2021, 110: 777-785. PMID: 33837531, PMCID: PMC8376807, DOI: 10.1002/cpt.2260.
- Feher A, Boutagy NE, Oikonomou EK, Liu YH, Miller EJ, Sinusas AJ, Hinchcliff M. Association Between Impaired Myocardial Flow Reserve on 82Rubidium Positron Emission Tomography Imaging and Adverse Events in Patients With Autoimmune Rheumatic Disease. Circulation. Cardiovascular Imaging 2021, 14: e012208. PMID: 34503339, PMCID: PMC8475774, DOI: 10.1161/CIRCIMAGING.120.012208.
- Liu H, Thorn S, Wu J, Fazzone-Chettiar R, Sandoval V, Miller EJ, Sinusas AJ, Liu YH. Quantification of myocardial blood flow (MBF) and reserve (MFR) incorporated with a novel segmentation approach: Assessments of quantitative precision and the lower limit of normal MBF and MFR in patients. Journal Of Nuclear Cardiology : Official Publication Of The American Society Of Nuclear Cardiology 2021, 28: 1236-1248. PMID: 32715416, DOI: 10.1007/s12350-020-02278-y.
- Liu H, Wu J, Miller EJ, Liu C, Yaqiang, Liu, Liu YH. Diagnostic accuracy of stress-only myocardial perfusion SPECT improved by deep learning. European Journal Of Nuclear Medicine And Molecular Imaging 2021, 48: 2793-2800. PMID: 33511425, DOI: 10.1007/s00259-021-05202-9.
- Dorbala S, Ando Y, Bokhari S, Dispenzieri A, Falk RH, Ferrari VA, Fontana M, Gheysens O, Gillmore JD, Glaudemans AWJM, Hanna MA, Hazenberg BPC, Kristen AV, Kwong RY, Maurer MS, Merlini G, Miller EJ, Moon JC, Murthy VL, Quarta CC, Rapezzi C, Ruberg FL, Shah SJ, Slart RHJA, Verberne HJ, Bourque JM. Addendum to ASNC/AHA/ASE/EANM/HFSA/ISA/SCMR/SNMMI expert consensus recommendations for multimodality imaging in cardiac amyloidosis: Part 1 of 2-evidence base and standardized methods of imaging. Journal Of Nuclear Cardiology : Official Publication Of The American Society Of Nuclear Cardiology 2021, 28: 1769-1774. PMID: 34196911, DOI: 10.1007/s12350-020-02455-z.
- Dorbala S, Ando Y, Bokhari S, Dispenzieri A, Falk RH, Ferrari VA, Fontana M, Gheysens O, Gillmore JD, Glaudemans AWJM, Hanna MA, Hazenberg BPC, Kristen AV, Kwong RY, Maurer MS, Merlini G, Miller EJ, Moon JC, Murthy VL, Quarta CC, Rapezzi C, Ruberg FL, Shah SJ, Slart RHJA, Verberne HJ, Bourque JM. Correction to: ASNC/AHA/ASE/EANM/HFSA/ISA/SCMR/SNMMI expert consensus recommendations for multimodality imaging in cardiac amyloidosis: Part 1 of 2-evidence base and standardized methods of imaging. Journal Of Nuclear Cardiology : Official Publication Of The American Society Of Nuclear Cardiology 2021, 28: 1761-1762. PMID: 34259978, DOI: 10.1007/s12350-021-02711-w.
- Dorbala S, Ando Y, Bokhari S, Dispenzieri A, Falk RH, Ferrari VA, Fontana M, Gheysens O, Gillmore JD, Glaudemans AWJM, Hanna MA, Hazenberg BPC, Kristen AV, Kwong RY, Maurer MS, Merlini G, Miller EJ, Moon JC, Murthy VL, Quarta CC, Rapezzi C, Ruberg FL, Shah SJ, Slart RHJA, Verberne HJ, Bourque JM. Correction to: ASNC/AHA/ASE/EANM/HFSA/ISA/SCMR/SNMMI Expert consensus recommendations for multimodality imaging in cardiac amyloidosis: Part 2 of 2-Diagnostic criteria and appropriate utilization. Journal Of Nuclear Cardiology : Official Publication Of The American Society Of Nuclear Cardiology 2021, 28: 1763-1767. PMID: 34279803, DOI: 10.1007/s12350-021-02712-9.
- Oikonomou EK, Van Dijk D, Parise H, Suchard MA, de Lemos J, Antoniades C, Velazquez EJ, Miller EJ, Khera R. A phenomapping-derived tool to personalize the selection of anatomical vs. functional testing in evaluating chest pain (ASSIST). European Heart Journal 2021, 42: 2536-2548. PMID: 33881513, PMCID: PMC8488385, DOI: 10.1093/eurheartj/ehab223.
- Eisenberg E, Miller RJH, Hu LH, Rios R, Betancur J, Azadani P, Han D, Sharir T, Einstein AJ, Bokhari S, Fish MB, Ruddy TD, Kaufmann PA, Sinusas AJ, Miller EJ, Bateman TM, Dorbala S, Di Carli M, Liang JX, Otaki Y, Tamarappoo BK, Dey D, Berman DS, Slomka PJ. Diagnostic safety of a machine learning-based automatic patient selection algorithm for stress-only myocardial perfusion SPECT. Journal Of Nuclear Cardiology : Official Publication Of The American Society Of Nuclear Cardiology 2021 PMID: 34228341, PMCID: PMC9020793, DOI: 10.1007/s12350-021-02698-4.
- Dorbala S, Ando Y, Bokhari S, Dispenzieri A, Falk RH, Ferrari VA, Fontana M, Gheysens O, Gillmore JD, Glaudemans AWJM, Hanna MA, Hazenberg BPC, Kristen AV, Kwong RY, Maurer MS, Merlini G, Miller EJ, Moon JC, Murthy VL, Quarta CC, Rapezzi C, Ruberg FL, Shah SJ, Slart RHJA, Verberne HJ, Bourque JM. ASNC/AHA/ASE/EANM/HFSA/ISA/SCMR/SNMMI Expert Consensus Recommendations for Multimodality Imaging in Cardiac Amyloidosis: Part 1 of 2-Evidence Base and Standardized Methods of Imaging. Circulation. Cardiovascular Imaging 2021, 14: e000029. PMID: 34196223, DOI: 10.1161/HCI.0000000000000029.
- Dorbala S, Ando Y, Bokhari S, Dispenzieri A, Falk RH, Ferrari VA, Fontana M, Gheysens O, Gillmore JD, Glaudemans AWJM, Hanna MA, Hazenberg BPC, Kristen AV, Kwong RY, Maurer MS, Merlini G, Miller EJ, Moon JC, Murthy VL, Quarta CC, Rapezzi C, Ruberg FL, Shah SJ, Slart RHJA, Verberne HJ, Bourque JM. ASNC/AHA/ASE/EANM/HFSA/ISA/SCMR/SNMMI Expert Consensus Recommendations for Multimodality Imaging in Cardiac Amyloidosis: Part 2 of 2-Diagnostic Criteria and Appropriate Utilization. Circulation. Cardiovascular Imaging 2021, 14: e000030. PMID: 34196222, DOI: 10.1161/HCI.0000000000000030.
- Kuronuma K, Miller RJH, Otaki Y, Van Kriekinge SD, Diniz MA, Sharir T, Hu LH, Gransar H, Liang JX, Parekh T, Kavanagh PB, Einstein AJ, Fish MB, Ruddy TD, Kaufmann PA, Sinusas AJ, Miller EJ, Bateman TM, Dorbala S, Di Carli M, Tamarappoo BK, Dey D, Berman DS, Slomka PJ. Prognostic Value of Phase Analysis for Predicting Adverse Cardiac Events Beyond Conventional Single-Photon Emission Computed Tomography Variables: Results From the REFINE SPECT Registry. Circulation. Cardiovascular Imaging 2021, 14: e012386. PMID: 34281372, PMCID: PMC8978932, DOI: 10.1161/CIRCIMAGING.120.012386.
- Chen X, Zhou B, Shi L, Liu H, Pang Y, Wang R, Miller EJ, Sinusas AJ, Liu C. CT-free attenuation correction for dedicated cardiac SPECT using a 3D dual squeeze-and-excitation residual dense network. Journal Of Nuclear Cardiology : Official Publication Of The American Society Of Nuclear Cardiology 2021 PMID: 34085168, DOI: 10.1007/s12350-021-02672-0.
- Liu YH, Fazzone-Chettiar R, Sandoval V, Tsatkin V, Miller EJ, Sinusas AJ. New approach for quantification of left ventricular function from low-dose gated bloodpool SPECT: Validation and comparison with conventional methods in patients. Journal Of Nuclear Cardiology : Official Publication Of The American Society Of Nuclear Cardiology 2021, 28: 939-950. PMID: 31338796, DOI: 10.1007/s12350-019-01823-8.
- Gallegos C, Oikonomou EK, Grimshaw A, Gulati M, Young BD, Miller EJ. Non-steroidal treatment of cardiac sarcoidosis: A systematic review. International Journal Of Cardiology. Heart & Vasculature 2021, 34: 100782. PMID: 33997256, PMCID: PMC8105294, DOI: 10.1016/j.ijcha.2021.100782.
- Hu LH, Miller RJH, Sharir T, Commandeur F, Rios R, Einstein AJ, Fish MB, Ruddy TD, Kaufmann PA, Sinusas AJ, Miller EJ, Bateman TM, Dorbala S, Di Carli M, Liang JX, Eisenberg E, Dey D, Berman DS, Slomka PJ. Prognostically safe stress-only single-photon emission computed tomography myocardial perfusion imaging guided by machine learning: report from REFINE SPECT. European Heart Journal Cardiovascular Imaging 2021, 22: 705-714. PMID: 32533137, DOI: 10.1093/ehjci/jeaa134.
- Gerber J, Miller EJ. Optimal interpretation of Tc99m PYP in 2020: Avoiding the million-dollar mistake. Journal Of Nuclear Cardiology : Official Publication Of The American Society Of Nuclear Cardiology 2021, 28: 503-506. PMID: 33442822, DOI: 10.1007/s12350-020-02503-8.
- Azadani PN, Miller RJH, Sharir T, Diniz MA, Hu LH, Otaki Y, Gransar H, Liang JX, Eisenberg E, Einstein AJ, Fish MB, Ruddy TD, Kaufmann PA, Sinusas AJ, Miller EJ, Bateman TM, Dorbala S, Di Carli M, Tamarappoo BK, Dey D, Berman DS, Slomka PJ. Impact of Early Revascularization on Major Adverse Cardiovascular Events in Relation to Automatically Quantified Ischemia. JACC. Cardiovascular Imaging 2021, 14: 644-653. PMID: 32828784, PMCID: PMC7987223, DOI: 10.1016/j.jcmg.2020.05.039.
- Rosenfeld LE, Chung MK, Harding CV, Spagnolo P, Grunewald J, Appelbaum J, Sauer WH, Culver DA, Joglar JA, Lin BA, Jellis CL, Dickfeld TM, Kwon DH, Miller EJ, Cremer PC, Bogun F, Kron J, Bock A, Mehta D, Leis P, Siontis KC, Kaufman ES, Crawford T, Zimetbaum P, Zishiri ET, Singh JP, Ellenbogen KA, Chrispin J, Quadri S, Vincent LL, Patton KK, Kalbfleish S, Callahan TD, Murgatroyd F, Judson MA, Birnie D, Okada DR, Maulion C, Bhat P, Bellumkonda L, Blankstein R, Cheng RK, Farr MA, Estep JD. Arrhythmias in Cardiac Sarcoidosis Bench to Bedside: A Case-Based Review. Circulation. Arrhythmia And Electrophysiology 2021, 14: e009203. PMID: 33591816, PMCID: PMC8142901, DOI: 10.1161/CIRCEP.120.009203.
- Torkaman M, Yang J, Shi L, Wang R, Miller EJ, Sinusas AJ, Liu C, Gullberg GT, Seo Y. Direct Image-Based Attenuation Correction using Conditional Generative Adversarial Network for SPECT Myocardial Perfusion Imaging. Proceedings Of SPIE--the International Society For Optical Engineering 2021, 11600 PMID: 33727759, PMCID: PMC7956874, DOI: 10.1117/12.2580922.
- Higgins AY, Annapureddy AR, Wang Y, Minges KE, Lampert R, Rosenfeld LE, Jacoby DL, Curtis JP, Miller EJ, Freeman JV. Survival Following Implantable Cardioverter-Defibrillator Implantation in Patients With Amyloid Cardiomyopathy. Journal Of The American Heart Association 2020, 9: e016038. PMID: 32867553, PMCID: PMC7726970, DOI: 10.1161/JAHA.120.016038.
- Hu LH, Sharir T, Miller RJH, Einstein AJ, Fish MB, Ruddy TD, Dorbala S, Di Carli M, Kaufmann PA, Sinusas AJ, Miller EJ, Bateman TM, Betancur J, Germano G, Liang JX, Commandeur F, Azadani PN, Gransar H, Otaki Y, Tamarappoo BK, Dey D, Berman DS, Slomka PJ. Upper reference limits of transient ischemic dilation ratio for different protocols on new-generation cadmium zinc telluride cameras: A report from REFINE SPECT registry. Journal Of Nuclear Cardiology : Official Publication Of The American Society Of Nuclear Cardiology 2020, 27: 1180-1189. PMID: 31087268, PMCID: PMC6851400, DOI: 10.1007/s12350-019-01730-y.
- Hindle-Katel W, Oen-Hsiao J, Lussnig E, Miller EJ. Incidental finding of COVID-19 pulmonary infiltrates on SPECT/CT attenuation correction CT. Journal Of Nuclear Cardiology : Official Publication Of The American Society Of Nuclear Cardiology 2020, 27: 1385-1386. PMID: 32394407, PMCID: PMC7213942, DOI: 10.1007/s12350-020-02178-1.
- Murthy VL, Bateman TM, Chen W, Malhotra S, Miller EJ, Ruddy TD, Dilsizian V. Impact of the ISCHEMIA Trial on Stress Nuclear Myocardial Perfusion Imaging. Journal Of Nuclear Medicine : Official Publication, Society Of Nuclear Medicine 2020, 61: 962-964. PMID: 32611712, PMCID: PMC7383082, DOI: 10.2967/jnumed.119.245399.
- Murthy VL, Bateman TM, Chen W, Malhotra S, Miller E, Ruddy T, Dilsizian V. Impact of the ISCHEMIA Trial on Stress Nuclear Myocardial Perfusion Imaging. Journal Of Nuclear Medicine : Official Publication, Society Of Nuclear Medicine 2020 PMID: 32513904, DOI: 10.2967/jnumed.120.245399.
- Slomka PJ, Betancur J, Liang JX, Otaki Y, Hu LH, Sharir T, Dorbala S, Di Carli M, Fish MB, Ruddy TD, Bateman TM, Einstein AJ, Kaufmann PA, Miller EJ, Sinusas AJ, Azadani PN, Gransar H, Tamarappoo BK, Dey D, Berman DS, Germano G. Rationale and design of the REgistry of Fast Myocardial Perfusion Imaging with NExt generation SPECT (REFINE SPECT). Journal Of Nuclear Cardiology : Official Publication Of The American Society Of Nuclear Cardiology 2020, 27: 1010-1021. PMID: 29923104, PMCID: PMC6301135, DOI: 10.1007/s12350-018-1326-4.
- Gallegos C, Miller EJ. Advances in PET-Based Cardiac Amyloid Radiotracers. Current Cardiology Reports 2020, 22: 40. PMID: 32430600, DOI: 10.1007/s11886-020-01284-3.
- Miller RJH, Hu LH, Gransar H, Betancur J, Eisenberg E, Otaki Y, Sharir T, Fish MB, Ruddy TD, Dorbala S, Carli MD, Einstein AJ, Kaufmann PA, Sinusas AJ, Miller EJ, Bateman T, Germano G, Tamarappoo BK, Dey D, Berman DS, Slomka PJ. Transient ischaemic dilation and post-stress wall motion abnormality increase risk in patients with less than moderate ischaemia: analysis of the REFINE SPECT registry. European Heart Journal Cardiovascular Imaging 2020, 21: 567-575. PMID: 31302679, PMCID: PMC7167750, DOI: 10.1093/ehjci/jez172.
- Hu LH, Betancur J, Sharir T, Einstein AJ, Bokhari S, Fish MB, Ruddy TD, Kaufmann PA, Sinusas AJ, Miller EJ, Bateman TM, Dorbala S, Di Carli M, Germano G, Commandeur F, Liang JX, Otaki Y, Tamarappoo BK, Dey D, Berman DS, Slomka PJ. Machine learning predicts per-vessel early coronary revascularization after fast myocardial perfusion SPECT: results from multicentre REFINE SPECT registry. European Heart Journal Cardiovascular Imaging 2020, 21: 549-559. PMID: 31317178, PMCID: PMC7167744, DOI: 10.1093/ehjci/jez177.
- Sharp MB, Soufer A, Abdelmessih M, Rosenfeld LE, Baldassarre LA, Miller EJ. Using FDG-PET to guide targeted cardiac magnetic resonance imaging in patients with suspected cardiac sarcoidosis. Journal Of Nuclear Cardiology : Official Publication Of The American Society Of Nuclear Cardiology 2020, 27: 688-690. PMID: 30737635, DOI: 10.1007/s12350-019-01640-z.
- Dorbala S, Ando Y, Bokhari S, Dispenzieri A, Falk RH, Ferrari VA, Fontana M, Gheysens O, Gillmore JD, Glaudemans AWJM, Hanna MA, Hazenberg BPC, Kristen AV, Kwong RY, Maurer MS, Merlini G, Miller EJ, Moon JC, Murthy VL, Quarta CC, Rapezzi C, Ruberg FL, Shah SJ, Slart RHJA, Verberne HJ, Bourque JM. ASNC/AHA/ASE/EANM/HFSA/ISA/SCMR/SNMMI expert consensus recommendations for multimodality imaging in cardiac amyloidosis: Part 2 of 2-Diagnostic criteria and appropriate utilization. Journal Of Nuclear Cardiology : Official Publication Of The American Society Of Nuclear Cardiology 2020, 27: 659-673. PMID: 31468377, DOI: 10.1007/s12350-019-01761-5.
- Miller EJ. Complex cellular physiology underlies the use of FDG-PET imaging in investigating post-infarction remodeling. Journal Of Nuclear Cardiology : Official Publication Of The American Society Of Nuclear Cardiology 2020, 27: 532-533. PMID: 31907858, DOI: 10.1007/s12350-019-02008-z.
- Otaki Y, Betancur J, Sharir T, Hu LH, Gransar H, Liang JX, Azadani PN, Einstein AJ, Fish MB, Ruddy TD, Kaufmann PA, Sinusas AJ, Miller EJ, Bateman TM, Dorbala S, Di Carli M, Tamarappoo BK, Germano G, Dey D, Berman DS, Slomka PJ. 5-Year Prognostic Value of Quantitative Versus Visual MPI in Subtle Perfusion Defects: Results From REFINE SPECT. JACC. Cardiovascular Imaging 2020, 13: 774-785. PMID: 31202740, PMCID: PMC6899217, DOI: 10.1016/j.jcmg.2019.02.028.
- Han D, Rozanski A, Gransar H, Sharir T, Einstein AJ, Fish MB, Ruddy TD, Kaufmann PA, Sinusas AJ, Miller EJ, Bateman TM, Dorbala S, Di Carli M, Liang JX, Hu LH, Germano G, Dey D, Berman DS, Slomka PJ. Myocardial Ischemic Burden and Differences in Prognosis Among Patients With and Without Diabetes: Results From the Multicenter International REFINE SPECT Registry. Diabetes Care 2020, 43: 453-459. PMID: 31776140, PMCID: PMC6971784, DOI: 10.2337/dc19-1360.
- Damsky W, Young BD, Sloan B, Miller EJ, Obando JA, King B. Treatment of Multiorgan Sarcoidosis With Tofacitinib. ACR Open Rheumatology 2020, 2: 106-109. PMID: 31916703, PMCID: PMC7011417, DOI: 10.1002/acr2.11112.
- Feher A, Srivastava A, Quail MA, Boutagy NE, Khanna P, Wilson L, Miller EJ, Liu YH, Lee F, Sinusas AJ. Serial Assessment of Coronary Flow Reserve by Rubidium-82 Positron Emission Tomography Predicts Mortality in Heart Transplant Recipients. JACC. Cardiovascular Imaging 2020, 13: 109-120. PMID: 30343093, PMCID: PMC6461525, DOI: 10.1016/j.jcmg.2018.08.025.
- Dorbala S, Ando Y, Bokhari S, Dispenzieri A, Falk RH, Ferrari VA, Fontana M, Gheysens O, Gillmore JD, Glaudemans AWJM, Hanna MA, Hazenberg BPC, Kristen AV, Kwong RY, Maurer MS, Merlini G, Miller EJ, Moon JC, Murthy VL, Quarta CC, Rapezzi C, Ruberg FL, Shah SJ, Slart RHJA, Verberne HJ, Bourque JM. ASNC/AHA/ASE/EANM/HFSA/ISA/SCMR/SNMMI expert consensus recommendations for multimodality imaging in cardiac amyloidosis: Part 1 of 2-evidence base and standardized methods of imaging. Journal Of Nuclear Cardiology : Official Publication Of The American Society Of Nuclear Cardiology 2019, 26: 2065-2123. PMID: 31468376, DOI: 10.1007/s12350-019-01760-6.
- Dorbala S, Ando Y, Bokhari S, Dispenzieri A, Falk RH, Ferrari VA, Fontana M, Gheysens O, Gillmore JD, Glaudemans AWJM, Hanna MA, Hazenberg BPC, Kristen AV, Kwong RY, Maurer MS, Merlini G, Miller EJ, Moon JC, Murthy VL, Quarta CC, Rapezzi C, Ruberg FL, Shah SJ, Slart RHJA, Verberne HJ, Bourque JM. ASNC/AHA/ASE/EANM/HFSA/ISA/SCMR/SNMMI Expert Consensus Recommendations for Multimodality Imaging in Cardiac Amyloidosis: Part 1 of 2-Evidence Base and Standardized Methods of Imaging. Journal Of Cardiac Failure 2019, 25: e1-e39. PMID: 31473268, DOI: 10.1016/j.cardfail.2019.08.001.
- Dorbala S, Ando Y, Bokhari S, Dispenzieri A, Falk RH, Ferrari VA, Fontana M, Gheysens O, Gillmore JD, Glaudemans AWJM, Hanna MA, Hazenberg BPC, Kristen AV, Kwong RY, Maurer MS, Merlini G, Miller EJ, Moon JC, Murthy VL, Quarta CC, Rapezzi C, Ruberg FL, Shah SJ, Slart RHJA, Verberne HJ, Bourque JM. ASNC/AHA/ASE/EANM/HFSA/ISA/SCMR/SNMMI Expert Consensus Recommendations for Multimodality Imaging in Cardiac Amyloidosis: Part 2 of 2-Diagnostic Criteria and Appropriate Utilization. Journal Of Cardiac Failure 2019, 25: 854-865. PMID: 31473267, DOI: 10.1016/j.cardfail.2019.08.002.
- Alvi RM, Young BD, Shahab Z, Pan H, Winkler J, Herzog E, Miller EJ. Repeatability and Optimization of FDG Positron Emission Tomography for Evaluation of Cardiac Sarcoidosis. JACC. Cardiovascular Imaging 2019, 12: 1284-1287. PMID: 30846271, DOI: 10.1016/j.jcmg.2019.01.011.
- Miller EJ, Jacoby D. Advanced Cardiac Imaging and the Complexity of Diagnosing Cardiac Sarcoidosis. Circulation. Cardiovascular Imaging 2019, 12: e009275. PMID: 31177819, DOI: 10.1161/CIRCIMAGING.119.009275.
- Betancur JA, Hu LH, Commandeur F, Sharir T, Einstein AJ, Fish MB, Ruddy TD, Kaufmann P, Sinusas AJ, Miller EJ, Bateman TM, Dorbala S, Di Carli M, Germano G, Otaki Y, Liang JX, Tamarappoo BK, Dey D, Berman DS, Slomka PJ. Deep Learning Analysis of Upright-Supine High-Efficiency SPECT Myocardial Perfusion Imaging for Prediction of Obstructive Coronary Artery Disease: A Multicenter Study. Journal Of Nuclear Medicine : Official Publication, Society Of Nuclear Medicine 2019, 60: 664-670. PMID: 30262516, PMCID: PMC6495237, DOI: 10.2967/jnumed.118.213538.
- Chen K, Miller EJ, Sadeghi MM. PET-Based Imaging of Ischemic Heart Disease. PET Clinics 2019, 14: 211-221. PMID: 30826019, PMCID: PMC6426655, DOI: 10.1016/j.cpet.2018.12.003.
- Betancur J, Commandeur F, Motlagh M, Sharir T, Einstein AJ, Bokhari S, Fish MB, Ruddy TD, Kaufmann P, Sinusas AJ, Miller EJ, Bateman TM, Dorbala S, Di Carli M, Germano G, Otaki Y, Tamarappoo BK, Dey D, Berman DS, Slomka PJ. Deep Learning for Prediction of Obstructive Disease From Fast Myocardial Perfusion SPECT: A Multicenter Study. JACC. Cardiovascular Imaging 2018, 11: 1654-1663. PMID: 29550305, PMCID: PMC6135711, DOI: 10.1016/j.jcmg.2018.01.020.
- Gallegos C, Miller EJ. Use of fluorine-18 sodium fluoride for the diagnosis of transthyretin cardiac amyloidosis: The birth of a new technique. Journal Of Nuclear Cardiology : Official Publication Of The American Society Of Nuclear Cardiology 2018, 25: 1568-1570. PMID: 28357811, DOI: 10.1007/s12350-017-0847-6.
- Higgins AY, Taylor EP, Baldassarre LA, Miller EJ, Rosenfeld LE. Diagnosis of extensive myocardial infiltration by diffuse large B-cell lymphoma using 18F-fluorodeoxyglucose positron emission tomography (18-FDG PET). Journal Of Nuclear Cardiology : Official Publication Of The American Society Of Nuclear Cardiology 2018, 25: 1869-1871. PMID: 29116563, DOI: 10.1007/s12350-017-1099-1.
- Boutagy NE, Wu J, Cai Z, Zhang W, Booth CJ, Kyriakides TC, Pfau D, Mulnix T, Liu Z, Miller EJ, Young LH, Carson RE, Huang Y, Liu C, Sinusas AJ. In Vivo Reactive Oxygen Species Detection With a Novel Positron Emission Tomography Tracer, 18F-DHMT, Allows for Early Detection of Anthracycline-Induced Cardiotoxicity in Rodents. JACC. Basic To Translational Science 2018, 3: 378-390. PMID: 30062224, PMCID: PMC6058999, DOI: 10.1016/j.jacbts.2018.02.003.
- Alvi R, Miller EJ, Hashemi Zonouz T, Sandoval V, Tariq N, Lampert R, Sinusas AJ, Liu YH. Quantification and Determination of Normal 123I-Meta Iodobenzylguanidine Heart-to-Mediastinum Ratio (HMR) from Cardiac SPECT/CT and Correlation with Planar HMR. Journal Of Nuclear Medicine : Official Publication, Society Of Nuclear Medicine 2018, 59: 652-658. PMID: 28916622, DOI: 10.2967/jnumed.117.197152.
- Slart RHJA, Glaudemans AWJM, Lancellotti P, Hyafil F, Blankstein R, Schwartz RG, Jaber WA, Russell R, Gimelli A, Rouzet F, Hacker M, Gheysens O, Plein S, Miller EJ, Dorbala S, Donal E. A joint procedural position statement on imaging in cardiac sarcoidosis: from the Cardiovascular and Inflammation & Infection Committees of the European Association of Nuclear Medicine, the European Association of Cardiovascular Imaging, and the American Society of Nuclear Cardiology. Journal Of Nuclear Cardiology : Official Publication Of The American Society Of Nuclear Cardiology 2018, 25: 298-319. PMID: 29043557, DOI: 10.1007/s12350-017-1043-4.
- Papoutsidakis N, Miller EJ, Rodonski A, Jacoby D. Time Course of Common Clinical Manifestations in Patients with Transthyretin Cardiac Amyloidosis: Delay From Symptom Onset to Diagnosis. Journal Of Cardiac Failure 2018, 24: 131-133. PMID: 29305186, DOI: 10.1016/j.cardfail.2017.12.005.
- Miller EJ, Culver DA. Establishing an Evidence-Based Method to Diagnose Cardiac Sarcoidosis: The Complementary Use of Cardiac Magnetic Resonance Imaging and FDG-PET. Circulation. Cardiovascular Imaging 2018, 11: e007408. PMID: 29335273, DOI: 10.1161/CIRCIMAGING.117.007408.
- Varghese M, Smiley D, Bellumkonda L, Rosenfeld LE, Lavanya B, Miller EJ. Quantitative interpretation of FDG PET for cardiac sarcoidosis reclassifies visually interpreted exams and potentially impacts downstream interventions. Sarcoidosis, Vasculitis, And Diffuse Lung Diseases : Official Journal Of WASOG / World Association Of Sarcoidosis And Other Granulomatous Disorders 2018, 35: 342-353. PMID: 32476922, PMCID: PMC7170132, DOI: 10.36141/svdld.v35i4.7342.
- Chareonthaitawee P, Beanlands RS, Chen W, Dorbala S, Miller EJ, Murthy VL, Birnie DH, Chen ES, Cooper LT, Tung RH, White ES, Borges-Neto S, Di Carli MF, Gropler RJ, Ruddy TD, Schindler TH, Blankstein R. Joint SNMMI-ASNC expert consensus document on the role of 18F-FDG PET/CT in cardiac sarcoid detection and therapy monitoring. Journal Of Nuclear Cardiology : Official Publication Of The American Society Of Nuclear Cardiology 2017, 24: 1741-1758. PMID: 28770463, DOI: 10.1007/s12350-017-0978-9.
- Salinaro F, Meier-Ewert HK, Miller EJ, Pandey S, Sanchorawala V, Berk JL, Seldin DC, Ruberg FL. Longitudinal systolic strain, cardiac function improvement, and survival following treatment of light-chain (AL) cardiac amyloidosis. European Heart Journal Cardiovascular Imaging 2017, 18: 1057-1064. PMID: 27965280, DOI: 10.1093/ehjci/jew298.
- Chareonthaitawee P, Beanlands RS, Chen W, Dorbala S, Miller EJ, Murthy VL, Birnie DH, Chen ES, Cooper LT, Tung RH, White ES, Borges-Neto S, Di Carli MF, Gropler RJ, Ruddy TD, Schindler TH, Blankstein R. Joint SNMMI-ASNC Expert Consensus Document on the Role of 18F-FDG PET/CT in Cardiac Sarcoid Detection and Therapy Monitoring. Journal Of Nuclear Medicine : Official Publication, Society Of Nuclear Medicine 2017, 58: 1341-1353. PMID: 28765228, PMCID: PMC6944184, DOI: 10.2967/jnumed.117.196287.
- Harb SC, Haq M, Flood K, Guerrieri A, Passerell W, Jaber WA, Miller EJ. National patterns in imaging utilization for diagnosis of cardiac amyloidosis: A focus on Tc99m-pyrophosphate scintigraphy. Journal Of Nuclear Cardiology : Official Publication Of The American Society Of Nuclear Cardiology 2017, 24: 1094-1097. PMID: 27016106, DOI: 10.1007/s12350-016-0478-3.
- Morse JC, Huang J, Khona N, Miller EJ, Siwik DA, Colucci WS, Hobai IA. Up-regulation of Intracellular Calcium Handling Underlies the Recovery of Endotoxemic Cardiomyopathy in Mice. Anesthesiology 2017, 126: 1125-1138. PMID: 28410273, DOI: 10.1097/ALN.0000000000001627.
- Haq M, Pawar S, Berk JL, Miller EJ, Ruberg FL. Can 99mTc-Pyrophosphate Aid in Early Detection of Cardiac Involvement in Asymptomatic Variant TTR Amyloidosis? JACC. Cardiovascular Imaging 2017, 10: 713-714. PMID: 27568122, PMCID: PMC5318295, DOI: 10.1016/j.jcmg.2016.06.003.
- Patchett ND, Pawar S, Miller EJ. Visual identification of coronary calcifications on attenuation correction CT improves diagnostic accuracy of SPECT/CT myocardial perfusion imaging. Journal Of Nuclear Cardiology : Official Publication Of The American Society Of Nuclear Cardiology 2017, 24: 711-720. PMID: 26850031, DOI: 10.1007/s12350-016-0395-5.
- Ahmadian A, Pawar S, Govender P, Berman J, Ruberg FL, Miller EJ. The response of FDG uptake to immunosuppressive treatment on FDG PET/CT imaging for cardiac sarcoidosis. Journal Of Nuclear Cardiology : Official Publication Of The American Society Of Nuclear Cardiology 2017, 24: 413-424. PMID: 27457527, DOI: 10.1007/s12350-016-0490-7.
- Blankstein R, Miller EJ. Quantifying FDG uptake to diagnose cardiac device infections: When and how should we do it? Journal Of Nuclear Cardiology : Official Publication Of The American Society Of Nuclear Cardiology 2016, 23: 1467-1469. PMID: 26494648, DOI: 10.1007/s12350-015-0293-2.
- Castano A, Haq M, Narotsky DL, Goldsmith J, Weinberg RL, Morgenstern R, Pozniakoff T, Ruberg FL, Miller EJ, Berk JL, Dispenzieri A, Grogan M, Johnson G, Bokhari S, Maurer MS. Multicenter Study of Planar Technetium 99m Pyrophosphate Cardiac Imaging: Predicting Survival for Patients With ATTR Cardiac Amyloidosis. JAMA Cardiology 2016, 1: 880-889. PMID: 27557400, DOI: 10.1001/jamacardio.2016.2839.
- Gillmore JD, Maurer MS, Falk RH, Merlini G, Damy T, Dispenzieri A, Wechalekar AD, Berk JL, Quarta CC, Grogan M, Lachmann HJ, Bokhari S, Castano A, Dorbala S, Johnson GB, Glaudemans AW, Rezk T, Fontana M, Palladini G, Milani P, Guidalotti PL, Flatman K, Lane T, Vonberg FW, Whelan CJ, Moon JC, Ruberg FL, Miller EJ, Hutt DF, Hazenberg BP, Rapezzi C, Hawkins PN. Nonbiopsy Diagnosis of Cardiac Transthyretin Amyloidosis. Circulation 2016, 133: 2404-12. PMID: 27143678, DOI: 10.1161/CIRCULATIONAHA.116.021612.
- Sverdlov AL, Elezaby A, Qin F, Behring JB, Luptak I, Calamaras TD, Siwik DA, Miller EJ, Liesa M, Shirihai OS, Pimentel DR, Cohen RA, Bachschmid MM, Colucci WS. Mitochondrial Reactive Oxygen Species Mediate Cardiac Structural, Functional, and Mitochondrial Consequences of Diet-Induced Metabolic Heart Disease. Journal Of The American Heart Association 2016, 5 PMID: 26755553, PMCID: PMC4859372, DOI: 10.1161/JAHA.115.002555.
- Miller EJ, Calamaras T, Elezaby A, Sverdlov A, Qin F, Luptak I, Wang K, Sun X, Vijay A, Croteau D, Bachschmid M, Cohen RA, Walsh K, Colucci WS. Partial Liver Kinase B1 (LKB1) Deficiency Promotes Diastolic Dysfunction, De Novo Systolic Dysfunction, Apoptosis, and Mitochondrial Dysfunction With Dietary Metabolic Challenge. Journal Of The American Heart Association 2015, 5 PMID: 26722122, PMCID: PMC4859355, DOI: 10.1161/JAHA.115.002277.
- Sung MM, Zordoky BN, Bujak AL, Lally JS, Fung D, Young ME, Horman S, Miller EJ, Light PE, Kemp BE, Steinberg GR, Dyck JR. AMPK deficiency in cardiac muscle results in dilated cardiomyopathy in the absence of changes in energy metabolism. Cardiovascular Research 2015, 107: 235-45. PMID: 26023060, PMCID: PMC4565988, DOI: 10.1093/cvr/cvv166.
- Elezaby A, Sverdlov AL, Tu VH, Soni K, Luptak I, Qin F, Liesa M, Shirihai OS, Rimer J, Schaffer JE, Colucci WS, Miller EJ. Mitochondrial remodeling in mice with cardiomyocyte-specific lipid overload. Journal Of Molecular And Cellular Cardiology 2015, 79: 275-83. PMID: 25497302, PMCID: PMC4301992, DOI: 10.1016/j.yjmcc.2014.12.001.
- Sverdlov AL, Elezaby A, Behring JB, Bachschmid MM, Luptak I, Tu VH, Siwik DA, Miller EJ, Liesa M, Shirihai OS, Pimentel DR, Cohen RA, Colucci WS. High fat, high sucrose diet causes cardiac mitochondrial dysfunction due in part to oxidative post-translational modification of mitochondrial complex II. Journal Of Molecular And Cellular Cardiology 2015, 78: 165-73. PMID: 25109264, PMCID: PMC4268348, DOI: 10.1016/j.yjmcc.2014.07.018.
- Ahmadian A, Brogan A, Berman J, Sverdlov AL, Mercier G, Mazzini M, Govender P, Ruberg FL, Miller EJ. Quantitative interpretation of FDG PET/CT with myocardial perfusion imaging increases diagnostic information in the evaluation of cardiac sarcoidosis. Journal Of Nuclear Cardiology : Official Publication Of The American Society Of Nuclear Cardiology 2014, 21: 925-39. PMID: 24879453, DOI: 10.1007/s12350-014-9901-9.
- Ayalon N, Gopal DM, Mooney DM, Simonetti JS, Grossman JR, Dwivedi A, Donohue C, Perez AJ, Downing J, Gokce N, Miller EJ, Liang CS, Apovian CM, Colucci WS, Ho JE. Preclinical left ventricular diastolic dysfunction in metabolic syndrome. The American Journal Of Cardiology 2014, 114: 838-42. PMID: 25084691, PMCID: PMC4162746, DOI: 10.1016/j.amjcard.2014.06.013.
- Berman JS, Govender P, Ruberg FL, Mazzini M, Miller EJ. Scadding revisited: a proposed staging system for cardiac sarcoidosis. Sarcoidosis, Vasculitis, And Diffuse Lung Diseases : Official Journal Of WASOG / World Association Of Sarcoidosis And Other Granulomatous Disorders 2014, 31: 2-5. PMID: 24751447.
- Li J, Qi D, Cheng H, Hu X, Miller EJ, Wu X, Russell KS, Mikush N, Zhang J, Xiao L, Sherwin RS, Young LH. Urocortin 2 autocrine/paracrine and pharmacologic effects to activate AMP-activated protein kinase in the heart. Proceedings Of The National Academy Of Sciences Of The United States Of America 2013, 110: 16133-8. PMID: 24043794, PMCID: PMC3791748, DOI: 10.1073/pnas.1312775110.
- Ruberg FL, Miller EJ. Nuclear tracers for transthyretin cardiac amyloidosis: time to bone up? Circulation. Cardiovascular Imaging 2013, 6: 162-4. PMID: 23512778, DOI: 10.1161/CIRCIMAGING.113.000178.
- Qin F, Siwik DA, Luptak I, Hou X, Wang L, Higuchi A, Weisbrod RM, Ouchi N, Tu VH, Calamaras TD, Miller EJ, Verbeuren TJ, Walsh K, Cohen RA, Colucci WS. The polyphenols resveratrol and S17834 prevent the structural and functional sequelae of diet-induced metabolic heart disease in mice. Circulation 2012, 125: 1757-64, S1-6. PMID: 22388319, PMCID: PMC3354628, DOI: 10.1161/CIRCULATIONAHA.111.067801.
- Depuey EG, Mahmarian JJ, Miller TD, Einstein AJ, Hansen CL, Holly TA, Miller EJ, Polk DM, Samuel Wann L. Patient-centered imaging. Journal Of Nuclear Cardiology : Official Publication Of The American Society Of Nuclear Cardiology 2012, 19: 185-215. PMID: 22328324, DOI: 10.1007/s12350-012-9523-z.
- Russell RR, Abbott BG, Arrighi JA, Blankstein R, Faber TL, Mahmarian JJ, Miller EJ, Miller TD, Shaw LJ, Soman P, Travin MI. Highlights of the 2011 Scientific Session of the American Society of Nuclear Cardiology: Denver, Colorado, September 8-11, 2011. Journal Of Nuclear Cardiology : Official Publication Of The American Society Of Nuclear Cardiology 2012, 19: 158-64. PMID: 22071955, DOI: 10.1007/s12350-011-9479-4.
- Kim AS, Miller EJ, Wright TM, Li J, Qi D, Atsina K, Zaha V, Sakamoto K, Young LH. A small molecule AMPK activator protects the heart against ischemia-reperfusion injury. Journal Of Molecular And Cellular Cardiology 2011, 51: 24-32. PMID: 21402077, PMCID: PMC4005884, DOI: 10.1016/j.yjmcc.2011.03.003.
- Amundson D, Dadekian G, Etienne M, Gleeson T, Hicks T, Killian D, Kratovil K, Lewis C, Monsour M, Pasiuk B, Rhodes D, Miller EJ. Practicing internal medicine onboard the USNS COMFORT in the aftermath of the Haitian earthquake. Annals Of Internal Medicine 2010, 152: 733-7. PMID: 20197507, DOI: 10.7326/0003-4819-152-11-201006010-00215.
- Kim AS, Miller EJ, Young LH. AMP-activated protein kinase: a core signalling pathway in the heart. Acta Physiologica (Oxford, England) 2009, 196: 37-53. PMID: 19239414, DOI: 10.1111/j.1748-1716.2009.01978.x.
- Ozcan C, Miller EJ, Russell KS, Dewar ML, Rosenfeld LE. An unusual case of nonbacterial thrombotic (marantic) endocarditis. The Journal Of Thoracic And Cardiovascular Surgery 2009, 137: 239-41. PMID: 19154931, DOI: 10.1016/j.jtcvs.2008.01.019.
- Miller EJ, Li J, Leng L, McDonald C, Atsumi T, Bucala R, Young LH. Macrophage migration inhibitory factor stimulates AMP-activated protein kinase in the ischaemic heart. Nature 2008, 451: 578-82. PMID: 18235500, DOI: 10.1038/nature06504.
- Miller EJ, Li J, Sinusas KM, Holman GD, Young LH. Infusion of a biotinylated bis-glucose photolabel: a new method to quantify cell surface GLUT4 in the intact mouse heart. American Journal Of Physiology. Endocrinology And Metabolism 2007, 292: E1922-8. PMID: 17341550, DOI: 10.1152/ajpendo.00170.2006.
- Li J, Coven DL, Miller EJ, Hu X, Young ME, Carling D, Sinusas AJ, Young LH. Activation of AMPK alpha- and gamma-isoform complexes in the intact ischemic rat heart. American Journal Of Physiology. Heart And Circulatory Physiology 2006, 291: H1927-34. PMID: 16648175, DOI: 10.1152/ajpheart.00251.2006.
- Li J, Miller EJ, Ninomiya-Tsuji J, Russell RR, Young LH. AMP-activated protein kinase activates p38 mitogen-activated protein kinase by increasing recruitment of p38 MAPK to TAB1 in the ischemic heart. Circulation Research 2005, 97: 872-9. PMID: 16179588, DOI: 10.1161/01.RES.0000187458.77026.10.
- Baron SJ, Li J, Russell RR, Neumann D, Miller EJ, Tuerk R, Wallimann T, Hurley RL, Witters LA, Young LH. Dual mechanisms regulating AMPK kinase action in the ischemic heart. Circulation Research 2005, 96: 337-45. PMID: 15653571, DOI: 10.1161/01.RES.0000155723.53868.d2.
- Miller EJ. Doctors and torture. The New England Journal Of Medicine 2004, 351: 1571-4; author reply 1571-4. PMID: 15473022.
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