- Yale Dermatologic SurgeryTemple Medical Center40 Temple Street, Ste 5th Floor, Suite 5ANew Haven, CT 06510
David J Leffell Sr, MDCM, BS, ACHPN, ACNPC-AG
Biography
David J. Leffell, MD, is an internationally recognized expert in skin health and the founder and chief of the Dermatologic Surgery Program at Yale Medicine. The program, which began in 1988, is a national leader, combining the highest level of patient-focused care with ongoing research into the causes of skin cancer and melanoma.
“I was privileged to be able to pursue my vision of providing exceptional patient care, research and training,” says Dr. Leffell.
Dr. Leffell has treated over 35,000 skin cancer and melanoma patients in his 30-year career. By specializing in the diagnosis, treatment and prevention of skin cancer, melanoma and rare skin tumors, he has developed a unique expertise which he has been able to share with generations of future doctors.
Dr. Leffell, a professor of dermatology, plastic surgery and otolaryngology at Yale School of Medicine, derives great satisfaction from the daily opportunity to pass on his knowledge and skill to fellows and other doctors in training. He emphasizes the importance of communication in the doctor-patient relationship. “Everything central to being a doctor flows from that: compassion, understanding, and effectiveness as a healer,” he says.
An internationally known researcher in the field of skin cancer, Dr. Leffell was involved with the discovery of the gene (PTCH) for the most common form of skin cancer, called basal cell cancer.
He has collaborated in research focused on understanding skin cancer in young women. Important new research into why women are developing skin cancer more often than expected was triggered following Dr. Leffell’s observation of the phenomenon. He holds three patents, including one for a laser device which measures aging of skin.
In addition to his clinical and research work, Dr. Leffell has published over 170 papers and has been an editor of the world’s leading textbook of dermatology, Fitzpatrick’s Dermatology in General Medicine. He is the author of Manual of Skin Surgery and Total Skin: The Definitive Guide to Whole Skin Care for Life.
Beauty and creativity also inform his personal life. In his spare time, Dr. Leffell builds furniture from locally harvested wood, and is an avid photographer. He recently published a collection of photographs of northwest Connecticut titled Connecticut Pastoral.
“Art, scientific research and clinical diagnosis—at the microscope or with the patient—all have in common the fundamental element of seeing or extracting a pattern. Once you can see the pattern, you can understand,” says Dr. Leffell.
Titles
- David P. Smith Professor of Dermatology and Professor of Surgery (Otolaryngology and Plastic)
- Deputy Dean Clinical Affairs, Yale School of Medicine
- Section Chief, Dermatologic Surgery and Cutaneous Oncology
- TITLE NON YALE, S.W.I.M, NAME OF INSTITUTION
Education & Training
- BSYale College, Biology (2039)
- AATest inst , Dept./Major (2024)
- training positioninst (2024)
- FellowUniversity of Michigan Medical School, Ann Arbor, MI (1988)
- N.I.H Postdoctoral FellowYale University School of Medicine, New Haven, CT (1987)
- ResidentYale-New Haven Hospital, New Haven, CT (1986)
- ResidentCornell Cooperating Hospitals (1984)
- InternCornell Cooperating Hospitals (1982)
- MDCMMcGill University (1981)
Languages Spoken
- English
- Français (French)
Additional Information
- Connecticut Magazine Top Docs 2016: Connecticut Magazine (2019)
- Best Doctors in New York: Castle and Connolly (2016)
- Best Doctors in America: Castle & Connolly (2014), (2015), (2016), (2017), (2018), (2019), (2020)
- Best Cancer Doctors in America: (2010), (2011), (2012), (2013), (2014), (2015), (2016), (2017), (2018)
- AB of Dermatology, Dermatology (1987, recertified: 2009)
- AB of Internal Medicine, Internal Medicine (1984)
- test comitee (2024): Abstract Grader
- Society for Investigative Dermatology, Committee on Resident/ Fellow Programs (2004 - 2008): Member
- Women's Dermatologic Society, Networking Committee (1998 - 2001): Member
- Women's Dermatologic Society, Mentorship Award Committee Women's Dermatologic Society, Mentorship Award Committee (1998 - 2001): Member
- citation
- citation
- Without URLcitation
- Titlecitation
- Beltrami E, Brown A, Salmon P, Leffell D, Ko J, Grant-Kels J. Artificial intelligence in the detection of skin cancer. Journal Of The American Academy Of Dermatology 2022, 87: 1336-1342. PMID: 35998842, DOI: 10.1016/j.jaad.2022.08.028.
- Kibbi N, Khan Y, Leffell DJ, Christensen SR, Suozzi KC. Predicting outcomes following second intent healing of periocular surgical defects. Archives Of Dermatological Research 2020, 313: 483-489. PMID: 32833078, DOI: 10.1007/s00403-020-02122-w.
- Prassinos A, Glusac E, Leffell DJ. Melanoma in situ: Don't make the cure worse than the disease. Journal Of The American Academy Of Dermatology 2020, 85: 520. PMID: 32387662, DOI: 10.1016/j.jaad.2020.04.168.
- Kibbi N, Zhang Y, Leffell DJ, Christensen SR. Photodynamic therapy for cutaneous squamous cell carcinoma in situ: Impact of anatomic location, tumor diameter, and incubation time on effectiveness. Journal Of The American Academy Of Dermatology 2019, 82: 1124-1130. PMID: 31712171, DOI: 10.1016/j.jaad.2019.10.079.
- Rodriguez‐Diaz E, Manolakos D, Christman H, Bonning MA, Geisse JK, A'Amar OM, Leffell DJ, Bigio IJ. Optical Spectroscopy as a Method for Skin Cancer Risk Assessment. Photochemistry And Photobiology 2019, 95: 1441-1445. PMID: 31287160, DOI: 10.1111/php.13140.
- Kibbi N, Suozzi KC, Ko CJ, Leffell DJ. Squamous Cell Carcinoma of the Lip in a Patient With Graft-Versus-Host Disease. Dermatologic Surgery 2019, Publish Ahead of Print: &na;. PMID: 31260417, DOI: 10.1097/dss.0000000000001706.
- Kibbi N, Suozzi K, Ko C, Leffell D. Squamous Cell Carcinoma of the Lip in a Patient With Graft-Versus-Host Disease. Dermatologic Surgery 2018, 1. DOI: 10.1097/00042728-900000000-98571.
- Totonchy MB, Leventhal JS, Ko CJ, Leffell DJ. Hypertrophic Lichen Planus and Well-Differentiated Squamous Cell Carcinoma. Dermatologic Surgery 2018, 44: 1466-1470. PMID: 29360655, DOI: 10.1097/dss.0000000000001465.
- Ko CJ, Myung P, Leffell DJ, Bourdon JC. Cutaneous immunohistochemical staining pattern of p53β isoforms. Journal Of Clinical Pathology 2018, 71: 1120. PMID: 30305316, DOI: 10.1136/jclinpath-2018-205098.
- Ezaldein HH, Scott JF, Yin ES, Ventura A, DeRuyter NP, Leffell DJ. Transparency and Dermatologic Device Approval by the US Food and Drug Administration. JAMA Dermatology 2018, 154: 273-280. PMID: 29365020, PMCID: PMC5885836, DOI: 10.1001/jamadermatol.2017.5757.
- Ferrucci LM, Cartmel B, Clare RA, Choy CC, Kershaw T, Leffell DJ, Mayne ST. Cross-sectional assessment of ultraviolet radiation–related behaviors among young people after a diagnosis of melanoma or basal cell carcinoma. Journal Of The American Academy Of Dermatology 2017, 79: 149-152. PMID: 29291957, PMCID: PMC6004335, DOI: 10.1016/j.jaad.2017.12.056.
- Totonchy M, Leffell D. Emerging concepts and recent advances in basal cell carcinoma. F1000Research 2017, 6: 2085. PMID: 29259776, PMCID: PMC5717469, DOI: 10.12688/f1000research.11314.1.
- Ko CJ, Glusac EJ, McNiff JM, Rodic N, Leffell DJ. Squamous proliferations on the legs of women: Qualitative examination of histopathology, TP53 sequencing, and implications for diagnosis in a series of 30 cases. Journal Of The American Academy Of Dermatology 2017, 77: 1126-1132.e1. PMID: 28709693, DOI: 10.1016/j.jaad.2017.04.1119.
- Panse G, Cowper SE, Leffell DJ, Pulitzer M, Ko CJ. Well‐differentiated neuroendocrine tumors in skin: Terminology and diagnostic utility of cytokeratin 5/6 and p63. Journal Of Cutaneous Pathology 2017, 44: 557-562. PMID: 28417484, DOI: 10.1111/cup.12952.
- Cartmel B, Bale AE, Mayne ST, Gelernter JE, DeWan AT, Spain P, Leffell DJ, Pagoto S, Ferrucci LM. Predictors of tanning dependence in white non‐Hispanic females and males. Journal Of The European Academy Of Dermatology And Venereology 2017, 31: 1223-1228. PMID: 28129487, PMCID: PMC5522341, DOI: 10.1111/jdv.14138.
- Zhang Y, Cartmel B, Choy CC, Molinaro AM, Leffell DJ, Bale AE, Mayne ST, Ferrucci LM. Body mass index, height and early-onset basal cell carcinoma in a case-control study. Cancer Epidemiology 2016, 46: 66-72. PMID: 28039770, PMCID: PMC5272867, DOI: 10.1016/j.canep.2016.12.007.
- Munday WR, Leffell DJ, McNiff JM, Ko CJ. Histopathologic features of multiple cutaneous squamous cell carcinomas of the lower extremity. Journal Of Cutaneous Pathology 2016, 43: 759-765. PMID: 27220356, DOI: 10.1111/cup.12738.
- Zhang Y, Cartmel B, Choy C, Molinaro A, Leffell D, Bale A, Mayne S, Ferucci L. Body mass index, height and early-onset basal cell carcinoma in a case-control study. Dermatology Online Journal 2016, 22 DOI: 10.5070/d3229032524.
- Cartmel B, Mayne S, Bale A, Gelernter J, DeWan A, Leffell D, Pagoto S, Spain P, Ferrucci L. Predictors of tanning dependence in white non-hispanic females and males. Dermatology Online Journal 2016, 22 DOI: 10.5070/d3229032556.
- Christensen SR, McNiff JM, Cool AJ, Aasi SZ, Hanlon AM, Leffell DJ. Histopathologic assessment of depth of follicular invasion of squamous cell carcinoma (SCC) in situ (SCCis): Implications for treatment approach. Journal Of The American Academy Of Dermatology 2015, 74: 356-362. PMID: 26670714, DOI: 10.1016/j.jaad.2015.09.060.
- Izikson R, Leffell DJ, Bock SA, Patriarca PA, Post P, Dunkle LM, Cox MM. Randomized comparison of the safety of Flublok® versus licensed inactivated influenza vaccine in healthy, medically stable adults ≥50 years of age. Vaccine 2015, 33: 6622-6628. PMID: 26529070, DOI: 10.1016/j.vaccine.2015.10.097.
- Berlin NL, Cartmel B, Leffell DJ, Bale AE, Mayne ST, Ferrucci LM. Family history of skin cancer is associated with early-onset basal cell carcinoma independent of MC1R genotype. Cancer Epidemiology 2015, 39: 1078-1083. PMID: 26381319, PMCID: PMC4679454, DOI: 10.1016/j.canep.2015.09.005.
- Higgins HW, Lee KC, Galan A, Leffell DJ. Melanoma in situ Part I. Epidemiology, screening, and clinical features. Journal Of The American Academy Of Dermatology 2015, 73: 181-190. PMID: 26183967, DOI: 10.1016/j.jaad.2015.04.014.
- Higgins HW, Lee KC, Galan A, Leffell DJ. Melanoma in situ Part II. Histopathology, treatment, and clinical management. Journal Of The American Academy Of Dermatology 2015, 73: 193-203. PMID: 26183968, DOI: 10.1016/j.jaad.2015.03.057.
- Berlin NL, Ferrucci LM, Cartmel B, Wang SY, Leffell DJ, McNiff JM, Mayne ST. Subsequent skin cancer in patients with early‐onset basal cell carcinoma. Australasian Journal Of Dermatology 2015, 56: 236-237. PMID: 26201376, DOI: 10.1111/ajd.12338.
- Molinaro AM, Ferrucci LM, Cartmel B, Loftfield E, Leffell DJ, Bale AE, Mayne ST. Indoor Tanning and the MC1R Genotype: Risk Prediction for Basal Cell Carcinoma Risk in Young People. American Journal Of Epidemiology 2015, 181: 908-916. PMID: 25858289, PMCID: PMC4445390, DOI: 10.1093/aje/kwu356.
- Kim J, Singh Maan H, Cool AJ, Hanlon AM, Leffell DJ. Fast Absorbing Gut Suture versus Cyanoacrylate Tissue Adhesive in the Epidermal Closure of Linear Repairs Following Mohs Micrographic Surgery. The Journal Of Clinical And Aesthetic Dermatology 2015, 8: 24-9. PMID: 25741400, PMCID: PMC4345930.
- Goldberg C, Hoang D, McRae M, Chung C, Leffell DJ, Narayan D. A Strategy for the Successful Management of Dermatofibrosarcoma Protuberans. Annals Of Plastic Surgery 2015, 74: 80-84. PMID: 23788146, DOI: 10.1097/sap.0b013e3182898692.
- Mendez JJ, Ghaedi M, Sivarapatna A, Dimitrievska S, Shao Z, Osuji CO, Steinbacher DM, Leffell DJ, Niklason LE. Mesenchymal stromal cells form vascular tubes when placed in fibrin sealant and accelerate wound healing in vivo. Biomaterials 2014, 40: 61-71. PMID: 25433608, PMCID: PMC4268422, DOI: 10.1016/j.biomaterials.2014.11.011.
- Zhang Y, Ferrucci LM, Cartmel B, Molinaro AM, Leffell DJ, Bale AE, Mayne ST. Alcohol intake and early‐onset basal cell carcinoma in a case–control study. British Journal Of Dermatology 2014, 171: 1451-1457. PMID: 25059635, PMCID: PMC4272627, DOI: 10.1111/bjd.13291.
- Cartmel B, Dewan A, Ferrucci LM, Gelernter J, Stapleton J, Leffell DJ, Mayne ST, Bale AE. Novel gene identified in an exome‐wide association study of tanning dependence. Experimental Dermatology 2014, 23: 757-759. PMID: 25041255, PMCID: PMC4204712, DOI: 10.1111/exd.12503.
- Ferrucci LM, Cartmel B, Molinaro AM, Leffell DJ, Bale AE, Mayne ST. Tea, coffee, and caffeine and early-onset basal cell carcinoma in a case–control study. European Journal Of Cancer Prevention 2014, 23: 296-302. PMID: 24841641, PMCID: PMC4059399, DOI: 10.1097/cej.0000000000000037.
- Troche JR, Ferrucci LM, Cartmel B, Leffell DJ, Bale AE, Mayne ST. Systemic glucocorticoid use and early-onset basal cell carcinoma. Annals Of Epidemiology 2014, 24: 625-627. PMID: 24958637, PMCID: PMC4119504, DOI: 10.1016/j.annepidem.2014.05.009.
- Higgins HW, Lee KC, Leffell DJ. Point of care cutaneous imaging technology in melanoma screening and mole mapping. Faculty Reviews 2014, 6: 34. PMID: 24860656, PMCID: PMC4017910, DOI: 10.12703/p6-34.
- Hanlon A, Kim J, Leffell DJ. Intralesional interferon alfa-2b for refractory, recurrent squamous cell carcinoma of the face. Journal Of The American Academy Of Dermatology 2013, 69: 1070-1072. PMID: 24238178, DOI: 10.1016/j.jaad.2013.02.032.
- Kim C, Ko CJ, Leffell DJ. Cutaneous squamous cell carcinomas of the lower extremity: A distinct subset of squamous cell carcinomas. Journal Of The American Academy Of Dermatology 2013, 70: 70-74. PMID: 24210370, DOI: 10.1016/j.jaad.2013.09.026.
- Cartmel B, Ferrucci LM, Spain P, Bale AE, Pagoto SL, Leffell DJ, Gelernter J, Mayne ST. Indoor Tanning and Tanning Dependence in Young People After a Diagnosis of Basal Cell Carcinoma. JAMA Dermatology 2013, 149: 1110-1111. PMID: 23824273, PMCID: PMC3782995, DOI: 10.1001/jamadermatol.2013.5104.
- Scarmo S, Cartmel B, Lin H, Leffell DJ, Ermakov IV, Gellermann W, Bernstein PS, Mayne ST. Single v. multiple measures of skin carotenoids by resonance Raman spectroscopy as a biomarker of usual carotenoid status. British Journal Of Nutrition 2013, 110: 911-917. PMID: 23351238, PMCID: PMC3696054, DOI: 10.1017/s000711451200582x.
- Aasi S, Leffell D, Lazova R. Atlas of Practical Mohs Histopathology. 2013 DOI: 10.1007/978-1-4614-5161-7.
- Bunick CG, Leffell D, Bosenberg M, Yahalom J, Choi JN. Cutaneous Rosai-Dorfman disease of the right ear responsive to radiotherapy. Journal Of The American Academy Of Dermatology 2012, 67: e225-e226. PMID: 23062927, DOI: 10.1016/j.jaad.2012.04.025.
- Jedrych J, Leffell D, McNiff JM. Desmoplastic trichoepithelioma with perineural involvement: a series of seven cases. Journal Of Cutaneous Pathology 2012, 39: 317-323. PMID: 22335590, DOI: 10.1111/j.1600-0560.2012.01876.x.
- Lostritto K, Ferrucci LM, Cartmel B, Leffell DJ, Molinaro AM, Bale AE, Mayne ST. Lifetime history of indoor tanning in young people: a retrospective assessment of initiation, persistence, and correlates. BMC Public Health 2012, 12: 118. PMID: 22324969, PMCID: PMC3340300, DOI: 10.1186/1471-2458-12-118.
- Heffelfinger C, Ouyang Z, Engberg A, Leffell DJ, Hanlon AM, Gordon PB, Zheng W, Zhao H, Snyder MP, Bale AE. Correlation of Global MicroRNA Expression With Basal Cell Carcinoma Subtype. G3: Genes, Genomes, Genetics 2012, 2: 279-286. PMID: 22384406, PMCID: PMC3284335, DOI: 10.1534/g3.111.001115.
- Ferrucci LM, Cartmel B, Molinaro AM, Leffell DJ, Bale AE, Mayne ST. Indoor tanning and risk of early-onset basal cell carcinoma. Journal Of The American Academy Of Dermatology 2011, 67: 552-562. PMID: 22153793, PMCID: PMC3307842, DOI: 10.1016/j.jaad.2011.11.940.
- Ferrucci LM, Cartmel B, Molinaro AM, Gordon PB, Leffell DJ, Bale AE, Mayne ST. Host Phenotype Characteristics and MC1R in Relation to Early-Onset Basal Cell Carcinoma. Journal Of Investigative Dermatology 2011, 132: 1272-1279. PMID: 22158557, PMCID: PMC3305835, DOI: 10.1038/jid.2011.402.
- Choi JN, Hanlon A, Leffell D. Melanoma and Nevi: Detection and Diagnosis. Current Problems In Cancer 2011, 35: 138-161. PMID: 21911179, DOI: 10.1016/j.currproblcancer.2011.07.005.
- Colegio O, Leffell D. Chapter 2 Genetics of Skin Cancer. 2011, 12-22. DOI: 10.1016/b978-1-4377-1788-4.00002-2.
- Mayne ST, Cartmel B, Scarmo S, Lin H, Leffell DJ, Welch E, Ermakov I, Bhosale P, Bernstein PS, Gellermann W. Noninvasive assessment of dermal carotenoids as a biomarker of fruit and vegetable intake. American Journal Of Clinical Nutrition 2010, 92: 794-800. PMID: 20685953, PMCID: PMC3133234, DOI: 10.3945/ajcn.2010.29707.
- Scarmo S, Cartmel B, Lin H, Leffell DJ, Welch E, Bhosale P, Bernstein PS, Mayne ST. Significant correlations of dermal total carotenoids and dermal lycopene with their respective plasma levels in healthy adults. Archives Of Biochemistry And Biophysics 2010, 504: 34-39. PMID: 20637178, PMCID: PMC2957565, DOI: 10.1016/j.abb.2010.07.004.
- Terushkin E, Leffell DJ, Futoryan T, Cowper S, Lazova R. Squamoid Eccrine Ductal Carcinoma: A Case Report and Review of the Literature. American Journal Of Dermatopathology 2010, 32: 287-292. PMID: 20010402, DOI: 10.1097/dad.0b013e3181b623c4.
- Book S, Aasi S, Leffell D. 16 Ellipse, Ellipse Variations, and Dog-ear Repairs. 2010, 239-250. DOI: 10.1016/b978-0-323-06575-7.00016-x.
- Ko CJ, Leffell DJ, McNiff JM. Adenosquamous carcinoma: a report of nine cases with p63 and cytokeratin 5/6 staining. Journal Of Cutaneous Pathology 2009, 36: 448-452. PMID: 19278431, DOI: 10.1111/j.1600-0560.2008.01083.x.
- Mariwalla K, Aasi SZ, Glusac EJ, Leffell DJ. Mohs micrographic surgery histopathology concordance. Journal Of The American Academy Of Dermatology 2009, 60: 94-98. PMID: 19103361, PMCID: PMC2632938, DOI: 10.1016/j.jaad.2008.09.061.
- NEWMAN J, LEFFELL D. Letter. Dermatologic Surgery 2008, 34: 853. DOI: 10.1097/00042728-200806000-00030.
- NEWMAN J, LEFFELL D. Reply. Dermatologic Surgery 2008, 34: 853-853. DOI: 10.1111/j.1524-4725.2008.34161_1.x.
- Aasi S, Leffell D. Free Margin Distortion. 2008, 95-114. DOI: 10.1007/978-0-387-73152-0_9.
- NEWMAN J, LEFFELL D. Correlation of Embryonic Fusion Planes with the Anatomical Distribution of Basal Cell Carcinoma. Dermatologic Surgery 2007, 33: 957-965. DOI: 10.1097/00042728-200708000-00009.
- Neville JA, Welch E, Leffell DJ. Management of nonmelanoma skin cancer in 2007. Nature Reviews Clinical Oncology 2007, 4: 462-469. PMID: 17657251, DOI: 10.1038/ncponc0883.
- NEWMAN JC, LEFFELL DJ. Correlation of Embryonic Fusion Planes with the Anatomical Distribution of Basal Cell Carcinoma. Dermatologic Surgery 2007, 33: 957-965. PMID: 17661939, DOI: 10.1111/j.1524-4725.2007.33198.x.
- Pennington B, Bolognia J, Leffell D. Flip‐Top Pigment Transplantation. 2006, 134-138. DOI: 10.1002/9780470987568.ch17.
- Bhattacharjee P, Leffell D, McNiff JM. Primary cutaneous carcinosarcoma arising in a patient with nevoid basal cell carcinoma syndrome. Journal Of Cutaneous Pathology 2005, 32: 638-641. PMID: 16176303, DOI: 10.1111/j.0303-6987.2005.00384.x.
- Pennington BE, Leffell DJ. Mohs micrographic surgery: established uses and emerging trends. Oncology 2005, 19: 1165-71; discussion 1171-2, 1175. PMID: 16255133.
- Pennington B, Leffell D. Book Review. New England Journal Of Medicine 2005, 352: 2657-2657. DOI: 10.1056/nejm200506233522525.
- Asplund A, Gustafsson AC, Wikonkal NM, Sela A, Leffell DJ, Kidd K, Lundeberg J, Brash DE, Pontén F. PTCH codon 1315 polymorphism and risk for nonmelanoma skin cancer. British Journal Of Dermatology 2005, 152: 868-873. PMID: 15888139, DOI: 10.1111/j.1365-2133.2005.06464.x.
- Book S, Aasi S, Leffell D. Chapter 18 Ellipse, Ellipse Variations, and Dog-ear Repairs. 2005, 259-272. DOI: 10.1016/b978-0-323-02752-6.50023-7.
- Aasi SZ, Leffell DJ. Bilobed transposition flap. Dermatologic Clinics 2005, 23: 55-64. PMID: 15620619, DOI: 10.1016/j.det.2004.08.004.
- Newman J, Leffell D. Correlation of embryonic fusion planes with the anatomical distribution of basal cell carcinoma1 1Disclosure not available at press time. Journal Of The American Academy Of Dermatology 2004, 50: p7. DOI: 10.1016/j.jaad.2003.10.032.
- Balfour E, Olhoffer I, Leffell D, Handerson T. Massive Pseudoepitheliomatous Hyperplasia: An Unusual Reaction to a Tattoo. American Journal Of Dermatopathology 2003, 25: 338-340. PMID: 12876493, DOI: 10.1097/00000372-200308000-00010.
- Aasi SZ, Leffell DJ. Complications in Dermatologic Surgery: How Safe Is Safe? JAMA Dermatology 2003, 139: 213-214. PMID: 12588228, DOI: 10.1001/archderm.139.2.213.
- Leffell DJ. Clinical Efficacy of Devices for Nonablative Photorejuvenation. JAMA Dermatology 2002, 138: 1503-1508. PMID: 12437458, DOI: 10.1001/archderm.138.11.1503.
- Olhoffer IH, Lazova R, Leffell DJ. Histopathologic misdiagnoses and their clinical consequences. JAMA Dermatology 2002, 138: 1381-3. PMID: 12374557, DOI: 10.1001/archderm.138.10.1381.
- CARUCCI J, KOLENIK S, LEFFELL D. Human Cadaveric Allograft for Repair of Nasal Defects After Extirpation of Basal Cell Carcinoma by Mohs Micrographic Surgery. Dermatologic Surgery 2002, 28: 340-343. DOI: 10.1097/00042728-200204000-00008.
- Carucci JA, Kolenik SA, Leffell DJ. Human Cadaveric Allograft for Repair of Nasal Defects After Extirpation of Basal Cell Carcinoma by Mohs Micrographic Surgery. Dermatologic Surgery 2002, 28: 340-343. PMID: 11966793, DOI: 10.1046/j.1524-4725.2002.01143.x.
- CARUCCI J, KOLENIK S, LEFFELL D. Repair of a Defect of the Lower Lip. Dermatologic Surgery 2002, 28: 195-196. DOI: 10.1097/00042728-200202000-00022.
- Carucci JA, Kolenik SA, Leffell DJ. Repair of a defect of the lower lip. Dermatologic Surgery : Official Publication For American Society For Dermatologic Surgery [et Al.] 2002, 28: 195-6. PMID: 11860438, DOI: 10.1046/j.1524-4725.2002.01250.x.
- Chen T, Yan W, Wells R, Rimm D, McNiff J, Leffell D, Reiss M. Novel inactivating mutations of transforming growth factor‐β type I receptor gene in head‐and‐neck cancer metastases. International Journal Of Cancer 2001, 93: 653-661. PMID: 11477574, DOI: 10.1002/ijc.1381.
- McGovern T, Leffell D. Surgical therapies, part II: flip‐top transplants in vitiligo. Dermatologic Therapy 2001, 14: 15-19. DOI: 10.1046/j.1529-8019.2001.014001015.x.
- Asgari M, Leffell D. Common Benign and Malignant Skin Lesions. 2001, 867-884. DOI: 10.1007/978-1-4757-3432-4_61.
- Grekin R, Tope W, Yarborough J, Olhoffer I, Lee P, Leffell D, Zachary C. Electrosurgical Facial Resurfacing: A Prospective Multicenter Study of Efficacy and Safety. JAMA Dermatology 2000, 136: 1309-1316. PMID: 11074690, DOI: 10.1001/archderm.136.11.1309.
- Carucci J, Leffell D. Intralesional interferon alfa for treatment of recurrent lentigo maligna of the eyelid in a patient with primary acquired melanosis. JAMA Dermatology 2000, 136: 1415-6. PMID: 11074712, DOI: 10.1001/archderm.136.11.1415.
- Leffell D, Arndt K. The Dermatologic Surgery Issue: A New Face for the ARCHIVES. JAMA Dermatology 2000, 136: 1404-1404. PMID: 11074706, DOI: 10.1001/archderm.136.11.1404.
- Leffell D. The other side of the sun. The Lancet 2000, 356: 699. PMID: 11085686, DOI: 10.1016/s0140-6736(00)02625-8.
- Leffell D. The scientific basis of skin cancer. Journal Of The American Academy Of Dermatology 2000, 42: s18-s22. PMID: 10607352, DOI: 10.1067/mjd.2000.103340.
- McGovern T, Grossman D, Fitzgerald D, Glusac E, Leffell D. Status of residual tumor in patients with squamous cell carcinoma referred for Mohs micrographic surgery. JAMA Dermatology 1999, 135: 1557-9. PMID: 10606080, DOI: 10.1001/archderm.135.12.1557.
- McGovern T, Bolognia J, Leffell D. Flip-Top Pigment Transplantation: A Novel Transplantation Procedure for the Treatment of Depigmentation. JAMA Dermatology 1999, 135: 1305-1307. PMID: 10566827, DOI: 10.1001/archderm.135.11.1305.
- McGovern T, Leffell D. Mohs Surgery: The Informed View. JAMA Dermatology 1999, 135: 1255-1259. PMID: 10522675, DOI: 10.1001/archderm.135.10.1255.
- Kolenik S, McGovern T, Leffell D. Use of a Lyophilized Bovine Collagen Matrix in Postoperative Wound Healing. Dermatologic Surgery 1999, 25: 303-307. PMID: 10417587, DOI: 10.1046/j.1524-4725.1999.08230.x.
- Olhoffer I, Davidson D, Longley J, Glusac E, Leffell D. Facial bowenoid papulosis secondary to human papillomavirus type 16. British Journal Of Dermatology 1999, 140: 761-2. PMID: 10233343.
- Zitelli J, Skouge J, Greenway H, Albom M, Day C, Dinehart S, Fewkes J, Geronemus R, Maloney M, Monheit G, Parlette H, Roenigk R, Robertson D, Fish F, Johnson T, Leffell D. American College of Mohs Micrographic Surgery and Cutaneous Oncology. Dermatologic Surgery 1998, 24: 481-489. DOI: 10.1111/j.1524-4725.1998.tb04192.x.
- Jonason A, Kunala S, Price G, Restifo R, Spinelli H, Persing J, Leffell D, Tarone R, Brash D. Frequent clones of p53-mutated keratinocytes in normal human skin. Proceedings Of The National Academy Of Sciences Of The United States Of America 1996, 93: 14025-14029. PMID: 8943054, PMCID: PMC19488, DOI: 10.1073/pnas.93.24.14025.
- Gailani M, Ståhle-Bäckdahl M, Leffell D, Glyn M, Zaphiropoulos P, Undén A, Dean M, Brash D, Bale A, Toftgård R. The role of the human homologue of Drosophila patched in sporadic basal cell carcinomas. Nature Genetics 1996, 14: 78-81. PMID: 8782823, DOI: 10.1038/ng0996-78.
- Hahn H, Wicking C, Zaphiropoulos P, Gailani M, Shanley S, Chidambaram A, Vorechovsky I, Holmberg E, Unden A, Gillies S, Negus K, Smyth I, Pressman C, Leffell D, Gerrard B, Goldstein A, Dean M, Toftgard R, Chenevix-Trench G, Wainwright B, Bale A. Mutations of the Human Homolog of Drosophila patched in the Nevoid Basal Cell Carcinoma Syndrome. Cell 1996, 85: 841-851. PMID: 8681379, DOI: 10.1016/s0092-8674(00)81268-4.
- Ziegler A, Jonason A, Simon J, Leffell D, Brash DE. Tumor Suppressor Gene Mutations and Photocarcinogenesis. Photochemistry And Photobiology 1996, 63: 432-435. PMID: 8934758, DOI: 10.1111/j.1751-1097.1996.tb03064.x.
- Gailani M, Leffell D, Ziegler A, Gross E, Brash D, Bale A. Relationship Between Sunlight Exposure and a Key Genetic Alteration in Basal Cell Carcinoma. Journal Of The National Cancer Institute 1996, 88: 349-354. PMID: 8609643, DOI: 10.1093/jnci/88.6.349.
- Waldorf H, Kauvar A, Geronemus R, Leffell D. Remote fire with the pulsed dye laser: Risk and prevention. Journal Of The American Academy Of Dermatology 1996, 34: 503-506. PMID: 8609266, DOI: 10.1016/s0190-9622(96)90457-0.
- KOLENIK S, LEFFELL D. The Use of Cryopreserved Human Skin Allografts in Wound Healing following Mohs Surgery. Dermatologic Surgery 1995, 21: 615-620. PMID: 7606373, DOI: 10.1111/j.1524-4725.1995.tb00517.x.
- Bale A, Gailani M, Leffell D. The Gorlin syndrome gene: a tumor suppressor active in basal cell carcinogenesis and embryonic development. Proceedings Of The Association Of American Physicians 1995, 107: 253-7. PMID: 8624861.
- Morganroth G, Tigelaar R, Longley B, Luck L, Leffell D. Targetoid hemangioma associated with pregnancy and the menstrual cycle. Journal Of The American Academy Of Dermatology 1995, 32: 282-284. PMID: 7829718, DOI: 10.1016/0190-9622(95)90149-3.
- Bale A, Gailani M, Leffell D. Nevoid Basal Cell Carcinoma Syndrome. Journal Of Investigative Dermatology 1994, 103: s126-s130. DOI: 10.1038/jid.1994.23.
- Bale A, Gailani M, Leffell D. Nevoid basal cell carcinoma syndrome. Journal Of Investigative Dermatology 1994, 103: 126s-130s. PMID: 7963674, DOI: 10.1111/1523-1747.ep12399438.
- LEFFELL D, BERWICK M, BOLOGNIA J. The Effect of Pre‐Education on Patient Compliance with Full‐Body Examination in a Public Skin Cancer Screening. Dermatologic Surgery 1993, 19: 660-663. PMID: 8349904, DOI: 10.1111/j.1524-4725.1993.tb00407.x.
- Leffell D, Chen Y, Berwick M, Bolognia J. Interobserver agreement in a community skin cancer screening setting. Journal Of The American Academy Of Dermatology 1993, 28: 1003-1005. PMID: 8496441, DOI: 10.1016/s0190-9622(08)80653-6.
- Ziegler A, Leffell DJ, Kunala S, Sharma HW, Gailani M, Simon JA, Halperin AJ, Baden HP, Shapiro PE, Bale AE. Mutation hotspots due to sunlight in the p53 gene of nonmelanoma skin cancers. Proceedings Of The National Academy Of Sciences Of The United States Of America 1993, 90: 4216-4220. PMID: 8483937, PMCID: PMC46477, DOI: 10.1073/pnas.90.9.4216.
- Morganroth G, Leffell D. Nonexcisional Treatment of Benign and Premalignant Cutaneous Lesions. Clinics In Plastic Surgery 1993, 20: 91-104. PMID: 8420713, DOI: 10.1016/s0094-1298(20)30775-6.
- Leffell D, Thompson J. Lasers in Dermatology and Ophthalmology. Dermatologic Clinics 1992, 10: 687-700. PMID: 1395152, DOI: 10.1016/s0733-8635(18)30305-x.
- Developmental defects in gorlin syndrome related to a putative tumor suppressor gene on chromosome 9Gailani M, Bale S, Leffell D, DiGiovanna J, Peck G, Poliak S, Drum M, Pastakia B, McBride O, Kase R, Greene M, Mulvihill J, Bale A. Developmental defects in gorlin syndrome related to a putative tumor suppressor gene on chromosome 9. Cell 1992, 69: 111-117. PMID: 1348213, DOI: 10.1016/0092-8674(92)90122-s.
- Leffell DJ, Headington JT, Wong DS, Swanson NA. Aggressive-Growth Basal Cell Carcinoma in Young Adults. JAMA Dermatology 1991, 127: 1663-1667. PMID: 1952969, DOI: 10.1001/archderm.1991.01680100063005.
- Leffell D. An educational device for Mohs micrographic surgery. A three-dimensional model of basal cell carcinoma. Dermatologic Surgery 1991, 17: 498-501. PMID: 2040753.
- LEFFELL D, BROWN M, SWANSON N. Laser Vaporization: A Novel Treatment of Botryomycosis. Dermatologic Surgery 1989, 15: 703-705. PMID: 2501368, DOI: 10.1111/j.1524-4725.1989.tb03615.x.
- Leffell D, Stetz M, Milstone L, Deckelbaum L. In Vivo Fluorescence of Human Skin-Reply. JAMA Dermatology 1989, 125: 999-1000. DOI: 10.1001/archderm.1989.01670190133021.
- Leffell D, Stetz M, Milstone L, Deckelbaum L. In Vivo Fluorescence of Human Skin: A Potential Marker of Photoaging. JAMA Dermatology 1988, 124: 1514-1518. DOI: 10.1001/archderm.1988.01670100016005.
- Leffell DJ, Stetz ML, Milstone LM, Deckelbaum LI. In vivo fluorescence of human skin. A potential marker of photoaging. JAMA Dermatology 1988, 124: 1514-8. PMID: 3421727, DOI: 10.1001/archderm.124.10.1514.
- Leffell D, Braverman I. Familial multiple lipomatosis Report of a case and a review of the literature. Journal Of The American Academy Of Dermatology 1986, 15: 275-279. PMID: 3745530, DOI: 10.1016/s0190-9622(86)70166-7.
- Yale Dermatologic SurgeryTemple Medical Center40 Temple Street, Ste 5th Floor, Suite 5ANew Haven, CT 06510
Biography
David J. Leffell, MD, is an internationally recognized expert in skin health and the founder and chief of the Dermatologic Surgery Program at Yale Medicine. The program, which began in 1988, is a national leader, combining the highest level of patient-focused care with ongoing research into the causes of skin cancer and melanoma.
“I was privileged to be able to pursue my vision of providing exceptional patient care, research and training,” says Dr. Leffell.
Dr. Leffell has treated over 35,000 skin cancer and melanoma patients in his 30-year career. By specializing in the diagnosis, treatment and prevention of skin cancer, melanoma and rare skin tumors, he has developed a unique expertise which he has been able to share with generations of future doctors.
Dr. Leffell, a professor of dermatology, plastic surgery and otolaryngology at Yale School of Medicine, derives great satisfaction from the daily opportunity to pass on his knowledge and skill to fellows and other doctors in training. He emphasizes the importance of communication in the doctor-patient relationship. “Everything central to being a doctor flows from that: compassion, understanding, and effectiveness as a healer,” he says.
An internationally known researcher in the field of skin cancer, Dr. Leffell was involved with the discovery of the gene (PTCH) for the most common form of skin cancer, called basal cell cancer.
He has collaborated in research focused on understanding skin cancer in young women. Important new research into why women are developing skin cancer more often than expected was triggered following Dr. Leffell’s observation of the phenomenon. He holds three patents, including one for a laser device which measures aging of skin.
In addition to his clinical and research work, Dr. Leffell has published over 170 papers and has been an editor of the world’s leading textbook of dermatology, Fitzpatrick’s Dermatology in General Medicine. He is the author of Manual of Skin Surgery and Total Skin: The Definitive Guide to Whole Skin Care for Life.
Beauty and creativity also inform his personal life. In his spare time, Dr. Leffell builds furniture from locally harvested wood, and is an avid photographer. He recently published a collection of photographs of northwest Connecticut titled Connecticut Pastoral.
“Art, scientific research and clinical diagnosis—at the microscope or with the patient—all have in common the fundamental element of seeing or extracting a pattern. Once you can see the pattern, you can understand,” says Dr. Leffell.
Titles
- David P. Smith Professor of Dermatology and Professor of Surgery (Otolaryngology and Plastic)
- Deputy Dean Clinical Affairs, Yale School of Medicine
- Section Chief, Dermatologic Surgery and Cutaneous Oncology
- TITLE NON YALE, S.W.I.M, NAME OF INSTITUTION
Education & Training
- BSYale College, Biology (2039)
- AATest inst , Dept./Major (2024)
- training positioninst (2024)
- FellowUniversity of Michigan Medical School, Ann Arbor, MI (1988)
- N.I.H Postdoctoral FellowYale University School of Medicine, New Haven, CT (1987)
- ResidentYale-New Haven Hospital, New Haven, CT (1986)
- ResidentCornell Cooperating Hospitals (1984)
- InternCornell Cooperating Hospitals (1982)
- MDCMMcGill University (1981)
Languages Spoken
- English
- Français (French)
Additional Information
- Connecticut Magazine Top Docs 2016: Connecticut Magazine (2019)
- Best Doctors in New York: Castle and Connolly (2016)
- Best Doctors in America: Castle & Connolly (2014), (2015), (2016), (2017), (2018), (2019), (2020)
- Best Cancer Doctors in America: (2010), (2011), (2012), (2013), (2014), (2015), (2016), (2017), (2018)
- AB of Dermatology, Dermatology (1987, recertified: 2009)
- AB of Internal Medicine, Internal Medicine (1984)
- test comitee (2024): Abstract Grader
- Society for Investigative Dermatology, Committee on Resident/ Fellow Programs (2004 - 2008): Member
- Women's Dermatologic Society, Networking Committee (1998 - 2001): Member
- Women's Dermatologic Society, Mentorship Award Committee Women's Dermatologic Society, Mentorship Award Committee (1998 - 2001): Member
- citation
- citation
- Without URLcitation
- Titlecitation
- Beltrami E, Brown A, Salmon P, Leffell D, Ko J, Grant-Kels J. Artificial intelligence in the detection of skin cancer. Journal Of The American Academy Of Dermatology 2022, 87: 1336-1342. PMID: 35998842, DOI: 10.1016/j.jaad.2022.08.028.
- Kibbi N, Khan Y, Leffell DJ, Christensen SR, Suozzi KC. Predicting outcomes following second intent healing of periocular surgical defects. Archives Of Dermatological Research 2020, 313: 483-489. PMID: 32833078, DOI: 10.1007/s00403-020-02122-w.
- Prassinos A, Glusac E, Leffell DJ. Melanoma in situ: Don't make the cure worse than the disease. Journal Of The American Academy Of Dermatology 2020, 85: 520. PMID: 32387662, DOI: 10.1016/j.jaad.2020.04.168.
- Kibbi N, Zhang Y, Leffell DJ, Christensen SR. Photodynamic therapy for cutaneous squamous cell carcinoma in situ: Impact of anatomic location, tumor diameter, and incubation time on effectiveness. Journal Of The American Academy Of Dermatology 2019, 82: 1124-1130. PMID: 31712171, DOI: 10.1016/j.jaad.2019.10.079.
- Rodriguez‐Diaz E, Manolakos D, Christman H, Bonning MA, Geisse JK, A'Amar OM, Leffell DJ, Bigio IJ. Optical Spectroscopy as a Method for Skin Cancer Risk Assessment. Photochemistry And Photobiology 2019, 95: 1441-1445. PMID: 31287160, DOI: 10.1111/php.13140.
- Kibbi N, Suozzi KC, Ko CJ, Leffell DJ. Squamous Cell Carcinoma of the Lip in a Patient With Graft-Versus-Host Disease. Dermatologic Surgery 2019, Publish Ahead of Print: &na;. PMID: 31260417, DOI: 10.1097/dss.0000000000001706.
- Kibbi N, Suozzi K, Ko C, Leffell D. Squamous Cell Carcinoma of the Lip in a Patient With Graft-Versus-Host Disease. Dermatologic Surgery 2018, 1. DOI: 10.1097/00042728-900000000-98571.
- Totonchy MB, Leventhal JS, Ko CJ, Leffell DJ. Hypertrophic Lichen Planus and Well-Differentiated Squamous Cell Carcinoma. Dermatologic Surgery 2018, 44: 1466-1470. PMID: 29360655, DOI: 10.1097/dss.0000000000001465.
- Ko CJ, Myung P, Leffell DJ, Bourdon JC. Cutaneous immunohistochemical staining pattern of p53β isoforms. Journal Of Clinical Pathology 2018, 71: 1120. PMID: 30305316, DOI: 10.1136/jclinpath-2018-205098.
- Ezaldein HH, Scott JF, Yin ES, Ventura A, DeRuyter NP, Leffell DJ. Transparency and Dermatologic Device Approval by the US Food and Drug Administration. JAMA Dermatology 2018, 154: 273-280. PMID: 29365020, PMCID: PMC5885836, DOI: 10.1001/jamadermatol.2017.5757.
- Ferrucci LM, Cartmel B, Clare RA, Choy CC, Kershaw T, Leffell DJ, Mayne ST. Cross-sectional assessment of ultraviolet radiation–related behaviors among young people after a diagnosis of melanoma or basal cell carcinoma. Journal Of The American Academy Of Dermatology 2017, 79: 149-152. PMID: 29291957, PMCID: PMC6004335, DOI: 10.1016/j.jaad.2017.12.056.
- Totonchy M, Leffell D. Emerging concepts and recent advances in basal cell carcinoma. F1000Research 2017, 6: 2085. PMID: 29259776, PMCID: PMC5717469, DOI: 10.12688/f1000research.11314.1.
- Ko CJ, Glusac EJ, McNiff JM, Rodic N, Leffell DJ. Squamous proliferations on the legs of women: Qualitative examination of histopathology, TP53 sequencing, and implications for diagnosis in a series of 30 cases. Journal Of The American Academy Of Dermatology 2017, 77: 1126-1132.e1. PMID: 28709693, DOI: 10.1016/j.jaad.2017.04.1119.
- Panse G, Cowper SE, Leffell DJ, Pulitzer M, Ko CJ. Well‐differentiated neuroendocrine tumors in skin: Terminology and diagnostic utility of cytokeratin 5/6 and p63. Journal Of Cutaneous Pathology 2017, 44: 557-562. PMID: 28417484, DOI: 10.1111/cup.12952.
- Cartmel B, Bale AE, Mayne ST, Gelernter JE, DeWan AT, Spain P, Leffell DJ, Pagoto S, Ferrucci LM. Predictors of tanning dependence in white non‐Hispanic females and males. Journal Of The European Academy Of Dermatology And Venereology 2017, 31: 1223-1228. PMID: 28129487, PMCID: PMC5522341, DOI: 10.1111/jdv.14138.
- Zhang Y, Cartmel B, Choy CC, Molinaro AM, Leffell DJ, Bale AE, Mayne ST, Ferrucci LM. Body mass index, height and early-onset basal cell carcinoma in a case-control study. Cancer Epidemiology 2016, 46: 66-72. PMID: 28039770, PMCID: PMC5272867, DOI: 10.1016/j.canep.2016.12.007.
- Munday WR, Leffell DJ, McNiff JM, Ko CJ. Histopathologic features of multiple cutaneous squamous cell carcinomas of the lower extremity. Journal Of Cutaneous Pathology 2016, 43: 759-765. PMID: 27220356, DOI: 10.1111/cup.12738.
- Zhang Y, Cartmel B, Choy C, Molinaro A, Leffell D, Bale A, Mayne S, Ferucci L. Body mass index, height and early-onset basal cell carcinoma in a case-control study. Dermatology Online Journal 2016, 22 DOI: 10.5070/d3229032524.
- Cartmel B, Mayne S, Bale A, Gelernter J, DeWan A, Leffell D, Pagoto S, Spain P, Ferrucci L. Predictors of tanning dependence in white non-hispanic females and males. Dermatology Online Journal 2016, 22 DOI: 10.5070/d3229032556.
- Christensen SR, McNiff JM, Cool AJ, Aasi SZ, Hanlon AM, Leffell DJ. Histopathologic assessment of depth of follicular invasion of squamous cell carcinoma (SCC) in situ (SCCis): Implications for treatment approach. Journal Of The American Academy Of Dermatology 2015, 74: 356-362. PMID: 26670714, DOI: 10.1016/j.jaad.2015.09.060.
- Izikson R, Leffell DJ, Bock SA, Patriarca PA, Post P, Dunkle LM, Cox MM. Randomized comparison of the safety of Flublok® versus licensed inactivated influenza vaccine in healthy, medically stable adults ≥50 years of age. Vaccine 2015, 33: 6622-6628. PMID: 26529070, DOI: 10.1016/j.vaccine.2015.10.097.
- Berlin NL, Cartmel B, Leffell DJ, Bale AE, Mayne ST, Ferrucci LM. Family history of skin cancer is associated with early-onset basal cell carcinoma independent of MC1R genotype. Cancer Epidemiology 2015, 39: 1078-1083. PMID: 26381319, PMCID: PMC4679454, DOI: 10.1016/j.canep.2015.09.005.
- Higgins HW, Lee KC, Galan A, Leffell DJ. Melanoma in situ Part I. Epidemiology, screening, and clinical features. Journal Of The American Academy Of Dermatology 2015, 73: 181-190. PMID: 26183967, DOI: 10.1016/j.jaad.2015.04.014.
- Higgins HW, Lee KC, Galan A, Leffell DJ. Melanoma in situ Part II. Histopathology, treatment, and clinical management. Journal Of The American Academy Of Dermatology 2015, 73: 193-203. PMID: 26183968, DOI: 10.1016/j.jaad.2015.03.057.
- Berlin NL, Ferrucci LM, Cartmel B, Wang SY, Leffell DJ, McNiff JM, Mayne ST. Subsequent skin cancer in patients with early‐onset basal cell carcinoma. Australasian Journal Of Dermatology 2015, 56: 236-237. PMID: 26201376, DOI: 10.1111/ajd.12338.
- Molinaro AM, Ferrucci LM, Cartmel B, Loftfield E, Leffell DJ, Bale AE, Mayne ST. Indoor Tanning and the MC1R Genotype: Risk Prediction for Basal Cell Carcinoma Risk in Young People. American Journal Of Epidemiology 2015, 181: 908-916. PMID: 25858289, PMCID: PMC4445390, DOI: 10.1093/aje/kwu356.
- Kim J, Singh Maan H, Cool AJ, Hanlon AM, Leffell DJ. Fast Absorbing Gut Suture versus Cyanoacrylate Tissue Adhesive in the Epidermal Closure of Linear Repairs Following Mohs Micrographic Surgery. The Journal Of Clinical And Aesthetic Dermatology 2015, 8: 24-9. PMID: 25741400, PMCID: PMC4345930.
- Goldberg C, Hoang D, McRae M, Chung C, Leffell DJ, Narayan D. A Strategy for the Successful Management of Dermatofibrosarcoma Protuberans. Annals Of Plastic Surgery 2015, 74: 80-84. PMID: 23788146, DOI: 10.1097/sap.0b013e3182898692.
- Mendez JJ, Ghaedi M, Sivarapatna A, Dimitrievska S, Shao Z, Osuji CO, Steinbacher DM, Leffell DJ, Niklason LE. Mesenchymal stromal cells form vascular tubes when placed in fibrin sealant and accelerate wound healing in vivo. Biomaterials 2014, 40: 61-71. PMID: 25433608, PMCID: PMC4268422, DOI: 10.1016/j.biomaterials.2014.11.011.
- Zhang Y, Ferrucci LM, Cartmel B, Molinaro AM, Leffell DJ, Bale AE, Mayne ST. Alcohol intake and early‐onset basal cell carcinoma in a case–control study. British Journal Of Dermatology 2014, 171: 1451-1457. PMID: 25059635, PMCID: PMC4272627, DOI: 10.1111/bjd.13291.
- Cartmel B, Dewan A, Ferrucci LM, Gelernter J, Stapleton J, Leffell DJ, Mayne ST, Bale AE. Novel gene identified in an exome‐wide association study of tanning dependence. Experimental Dermatology 2014, 23: 757-759. PMID: 25041255, PMCID: PMC4204712, DOI: 10.1111/exd.12503.
- Ferrucci LM, Cartmel B, Molinaro AM, Leffell DJ, Bale AE, Mayne ST. Tea, coffee, and caffeine and early-onset basal cell carcinoma in a case–control study. European Journal Of Cancer Prevention 2014, 23: 296-302. PMID: 24841641, PMCID: PMC4059399, DOI: 10.1097/cej.0000000000000037.
- Troche JR, Ferrucci LM, Cartmel B, Leffell DJ, Bale AE, Mayne ST. Systemic glucocorticoid use and early-onset basal cell carcinoma. Annals Of Epidemiology 2014, 24: 625-627. PMID: 24958637, PMCID: PMC4119504, DOI: 10.1016/j.annepidem.2014.05.009.
- Higgins HW, Lee KC, Leffell DJ. Point of care cutaneous imaging technology in melanoma screening and mole mapping. Faculty Reviews 2014, 6: 34. PMID: 24860656, PMCID: PMC4017910, DOI: 10.12703/p6-34.
- Hanlon A, Kim J, Leffell DJ. Intralesional interferon alfa-2b for refractory, recurrent squamous cell carcinoma of the face. Journal Of The American Academy Of Dermatology 2013, 69: 1070-1072. PMID: 24238178, DOI: 10.1016/j.jaad.2013.02.032.
- Kim C, Ko CJ, Leffell DJ. Cutaneous squamous cell carcinomas of the lower extremity: A distinct subset of squamous cell carcinomas. Journal Of The American Academy Of Dermatology 2013, 70: 70-74. PMID: 24210370, DOI: 10.1016/j.jaad.2013.09.026.
- Cartmel B, Ferrucci LM, Spain P, Bale AE, Pagoto SL, Leffell DJ, Gelernter J, Mayne ST. Indoor Tanning and Tanning Dependence in Young People After a Diagnosis of Basal Cell Carcinoma. JAMA Dermatology 2013, 149: 1110-1111. PMID: 23824273, PMCID: PMC3782995, DOI: 10.1001/jamadermatol.2013.5104.
- Scarmo S, Cartmel B, Lin H, Leffell DJ, Ermakov IV, Gellermann W, Bernstein PS, Mayne ST. Single v. multiple measures of skin carotenoids by resonance Raman spectroscopy as a biomarker of usual carotenoid status. British Journal Of Nutrition 2013, 110: 911-917. PMID: 23351238, PMCID: PMC3696054, DOI: 10.1017/s000711451200582x.
- Aasi S, Leffell D, Lazova R. Atlas of Practical Mohs Histopathology. 2013 DOI: 10.1007/978-1-4614-5161-7.
- Bunick CG, Leffell D, Bosenberg M, Yahalom J, Choi JN. Cutaneous Rosai-Dorfman disease of the right ear responsive to radiotherapy. Journal Of The American Academy Of Dermatology 2012, 67: e225-e226. PMID: 23062927, DOI: 10.1016/j.jaad.2012.04.025.
- Jedrych J, Leffell D, McNiff JM. Desmoplastic trichoepithelioma with perineural involvement: a series of seven cases. Journal Of Cutaneous Pathology 2012, 39: 317-323. PMID: 22335590, DOI: 10.1111/j.1600-0560.2012.01876.x.
- Lostritto K, Ferrucci LM, Cartmel B, Leffell DJ, Molinaro AM, Bale AE, Mayne ST. Lifetime history of indoor tanning in young people: a retrospective assessment of initiation, persistence, and correlates. BMC Public Health 2012, 12: 118. PMID: 22324969, PMCID: PMC3340300, DOI: 10.1186/1471-2458-12-118.
- Heffelfinger C, Ouyang Z, Engberg A, Leffell DJ, Hanlon AM, Gordon PB, Zheng W, Zhao H, Snyder MP, Bale AE. Correlation of Global MicroRNA Expression With Basal Cell Carcinoma Subtype. G3: Genes, Genomes, Genetics 2012, 2: 279-286. PMID: 22384406, PMCID: PMC3284335, DOI: 10.1534/g3.111.001115.
- Ferrucci LM, Cartmel B, Molinaro AM, Leffell DJ, Bale AE, Mayne ST. Indoor tanning and risk of early-onset basal cell carcinoma. Journal Of The American Academy Of Dermatology 2011, 67: 552-562. PMID: 22153793, PMCID: PMC3307842, DOI: 10.1016/j.jaad.2011.11.940.
- Ferrucci LM, Cartmel B, Molinaro AM, Gordon PB, Leffell DJ, Bale AE, Mayne ST. Host Phenotype Characteristics and MC1R in Relation to Early-Onset Basal Cell Carcinoma. Journal Of Investigative Dermatology 2011, 132: 1272-1279. PMID: 22158557, PMCID: PMC3305835, DOI: 10.1038/jid.2011.402.
- Choi JN, Hanlon A, Leffell D. Melanoma and Nevi: Detection and Diagnosis. Current Problems In Cancer 2011, 35: 138-161. PMID: 21911179, DOI: 10.1016/j.currproblcancer.2011.07.005.
- Colegio O, Leffell D. Chapter 2 Genetics of Skin Cancer. 2011, 12-22. DOI: 10.1016/b978-1-4377-1788-4.00002-2.
- Mayne ST, Cartmel B, Scarmo S, Lin H, Leffell DJ, Welch E, Ermakov I, Bhosale P, Bernstein PS, Gellermann W. Noninvasive assessment of dermal carotenoids as a biomarker of fruit and vegetable intake. American Journal Of Clinical Nutrition 2010, 92: 794-800. PMID: 20685953, PMCID: PMC3133234, DOI: 10.3945/ajcn.2010.29707.
- Scarmo S, Cartmel B, Lin H, Leffell DJ, Welch E, Bhosale P, Bernstein PS, Mayne ST. Significant correlations of dermal total carotenoids and dermal lycopene with their respective plasma levels in healthy adults. Archives Of Biochemistry And Biophysics 2010, 504: 34-39. PMID: 20637178, PMCID: PMC2957565, DOI: 10.1016/j.abb.2010.07.004.
- Terushkin E, Leffell DJ, Futoryan T, Cowper S, Lazova R. Squamoid Eccrine Ductal Carcinoma: A Case Report and Review of the Literature. American Journal Of Dermatopathology 2010, 32: 287-292. PMID: 20010402, DOI: 10.1097/dad.0b013e3181b623c4.
- Book S, Aasi S, Leffell D. 16 Ellipse, Ellipse Variations, and Dog-ear Repairs. 2010, 239-250. DOI: 10.1016/b978-0-323-06575-7.00016-x.
- Ko CJ, Leffell DJ, McNiff JM. Adenosquamous carcinoma: a report of nine cases with p63 and cytokeratin 5/6 staining. Journal Of Cutaneous Pathology 2009, 36: 448-452. PMID: 19278431, DOI: 10.1111/j.1600-0560.2008.01083.x.
- Mariwalla K, Aasi SZ, Glusac EJ, Leffell DJ. Mohs micrographic surgery histopathology concordance. Journal Of The American Academy Of Dermatology 2009, 60: 94-98. PMID: 19103361, PMCID: PMC2632938, DOI: 10.1016/j.jaad.2008.09.061.
- NEWMAN J, LEFFELL D. Letter. Dermatologic Surgery 2008, 34: 853. DOI: 10.1097/00042728-200806000-00030.
- NEWMAN J, LEFFELL D. Reply. Dermatologic Surgery 2008, 34: 853-853. DOI: 10.1111/j.1524-4725.2008.34161_1.x.
- Aasi S, Leffell D. Free Margin Distortion. 2008, 95-114. DOI: 10.1007/978-0-387-73152-0_9.
- NEWMAN J, LEFFELL D. Correlation of Embryonic Fusion Planes with the Anatomical Distribution of Basal Cell Carcinoma. Dermatologic Surgery 2007, 33: 957-965. DOI: 10.1097/00042728-200708000-00009.
- Neville JA, Welch E, Leffell DJ. Management of nonmelanoma skin cancer in 2007. Nature Reviews Clinical Oncology 2007, 4: 462-469. PMID: 17657251, DOI: 10.1038/ncponc0883.
- NEWMAN JC, LEFFELL DJ. Correlation of Embryonic Fusion Planes with the Anatomical Distribution of Basal Cell Carcinoma. Dermatologic Surgery 2007, 33: 957-965. PMID: 17661939, DOI: 10.1111/j.1524-4725.2007.33198.x.
- Pennington B, Bolognia J, Leffell D. Flip‐Top Pigment Transplantation. 2006, 134-138. DOI: 10.1002/9780470987568.ch17.
- Bhattacharjee P, Leffell D, McNiff JM. Primary cutaneous carcinosarcoma arising in a patient with nevoid basal cell carcinoma syndrome. Journal Of Cutaneous Pathology 2005, 32: 638-641. PMID: 16176303, DOI: 10.1111/j.0303-6987.2005.00384.x.
- Pennington BE, Leffell DJ. Mohs micrographic surgery: established uses and emerging trends. Oncology 2005, 19: 1165-71; discussion 1171-2, 1175. PMID: 16255133.
- Pennington B, Leffell D. Book Review. New England Journal Of Medicine 2005, 352: 2657-2657. DOI: 10.1056/nejm200506233522525.
- Asplund A, Gustafsson AC, Wikonkal NM, Sela A, Leffell DJ, Kidd K, Lundeberg J, Brash DE, Pontén F. PTCH codon 1315 polymorphism and risk for nonmelanoma skin cancer. British Journal Of Dermatology 2005, 152: 868-873. PMID: 15888139, DOI: 10.1111/j.1365-2133.2005.06464.x.
- Book S, Aasi S, Leffell D. Chapter 18 Ellipse, Ellipse Variations, and Dog-ear Repairs. 2005, 259-272. DOI: 10.1016/b978-0-323-02752-6.50023-7.
- Aasi SZ, Leffell DJ. Bilobed transposition flap. Dermatologic Clinics 2005, 23: 55-64. PMID: 15620619, DOI: 10.1016/j.det.2004.08.004.
- Newman J, Leffell D. Correlation of embryonic fusion planes with the anatomical distribution of basal cell carcinoma1 1Disclosure not available at press time. Journal Of The American Academy Of Dermatology 2004, 50: p7. DOI: 10.1016/j.jaad.2003.10.032.
- Balfour E, Olhoffer I, Leffell D, Handerson T. Massive Pseudoepitheliomatous Hyperplasia: An Unusual Reaction to a Tattoo. American Journal Of Dermatopathology 2003, 25: 338-340. PMID: 12876493, DOI: 10.1097/00000372-200308000-00010.
- Aasi SZ, Leffell DJ. Complications in Dermatologic Surgery: How Safe Is Safe? JAMA Dermatology 2003, 139: 213-214. PMID: 12588228, DOI: 10.1001/archderm.139.2.213.
- Leffell DJ. Clinical Efficacy of Devices for Nonablative Photorejuvenation. JAMA Dermatology 2002, 138: 1503-1508. PMID: 12437458, DOI: 10.1001/archderm.138.11.1503.
- Olhoffer IH, Lazova R, Leffell DJ. Histopathologic misdiagnoses and their clinical consequences. JAMA Dermatology 2002, 138: 1381-3. PMID: 12374557, DOI: 10.1001/archderm.138.10.1381.
- CARUCCI J, KOLENIK S, LEFFELL D. Human Cadaveric Allograft for Repair of Nasal Defects After Extirpation of Basal Cell Carcinoma by Mohs Micrographic Surgery. Dermatologic Surgery 2002, 28: 340-343. DOI: 10.1097/00042728-200204000-00008.
- Carucci JA, Kolenik SA, Leffell DJ. Human Cadaveric Allograft for Repair of Nasal Defects After Extirpation of Basal Cell Carcinoma by Mohs Micrographic Surgery. Dermatologic Surgery 2002, 28: 340-343. PMID: 11966793, DOI: 10.1046/j.1524-4725.2002.01143.x.
- CARUCCI J, KOLENIK S, LEFFELL D. Repair of a Defect of the Lower Lip. Dermatologic Surgery 2002, 28: 195-196. DOI: 10.1097/00042728-200202000-00022.
- Carucci JA, Kolenik SA, Leffell DJ. Repair of a defect of the lower lip. Dermatologic Surgery : Official Publication For American Society For Dermatologic Surgery [et Al.] 2002, 28: 195-6. PMID: 11860438, DOI: 10.1046/j.1524-4725.2002.01250.x.
- Chen T, Yan W, Wells R, Rimm D, McNiff J, Leffell D, Reiss M. Novel inactivating mutations of transforming growth factor‐β type I receptor gene in head‐and‐neck cancer metastases. International Journal Of Cancer 2001, 93: 653-661. PMID: 11477574, DOI: 10.1002/ijc.1381.
- McGovern T, Leffell D. Surgical therapies, part II: flip‐top transplants in vitiligo. Dermatologic Therapy 2001, 14: 15-19. DOI: 10.1046/j.1529-8019.2001.014001015.x.
- Asgari M, Leffell D. Common Benign and Malignant Skin Lesions. 2001, 867-884. DOI: 10.1007/978-1-4757-3432-4_61.
- Grekin R, Tope W, Yarborough J, Olhoffer I, Lee P, Leffell D, Zachary C. Electrosurgical Facial Resurfacing: A Prospective Multicenter Study of Efficacy and Safety. JAMA Dermatology 2000, 136: 1309-1316. PMID: 11074690, DOI: 10.1001/archderm.136.11.1309.
- Carucci J, Leffell D. Intralesional interferon alfa for treatment of recurrent lentigo maligna of the eyelid in a patient with primary acquired melanosis. JAMA Dermatology 2000, 136: 1415-6. PMID: 11074712, DOI: 10.1001/archderm.136.11.1415.
- Leffell D, Arndt K. The Dermatologic Surgery Issue: A New Face for the ARCHIVES. JAMA Dermatology 2000, 136: 1404-1404. PMID: 11074706, DOI: 10.1001/archderm.136.11.1404.
- Leffell D. The other side of the sun. The Lancet 2000, 356: 699. PMID: 11085686, DOI: 10.1016/s0140-6736(00)02625-8.
- Leffell D. The scientific basis of skin cancer. Journal Of The American Academy Of Dermatology 2000, 42: s18-s22. PMID: 10607352, DOI: 10.1067/mjd.2000.103340.
- McGovern T, Grossman D, Fitzgerald D, Glusac E, Leffell D. Status of residual tumor in patients with squamous cell carcinoma referred for Mohs micrographic surgery. JAMA Dermatology 1999, 135: 1557-9. PMID: 10606080, DOI: 10.1001/archderm.135.12.1557.
- McGovern T, Bolognia J, Leffell D. Flip-Top Pigment Transplantation: A Novel Transplantation Procedure for the Treatment of Depigmentation. JAMA Dermatology 1999, 135: 1305-1307. PMID: 10566827, DOI: 10.1001/archderm.135.11.1305.
- McGovern T, Leffell D. Mohs Surgery: The Informed View. JAMA Dermatology 1999, 135: 1255-1259. PMID: 10522675, DOI: 10.1001/archderm.135.10.1255.
- Kolenik S, McGovern T, Leffell D. Use of a Lyophilized Bovine Collagen Matrix in Postoperative Wound Healing. Dermatologic Surgery 1999, 25: 303-307. PMID: 10417587, DOI: 10.1046/j.1524-4725.1999.08230.x.
- Olhoffer I, Davidson D, Longley J, Glusac E, Leffell D. Facial bowenoid papulosis secondary to human papillomavirus type 16. British Journal Of Dermatology 1999, 140: 761-2. PMID: 10233343.
- Zitelli J, Skouge J, Greenway H, Albom M, Day C, Dinehart S, Fewkes J, Geronemus R, Maloney M, Monheit G, Parlette H, Roenigk R, Robertson D, Fish F, Johnson T, Leffell D. American College of Mohs Micrographic Surgery and Cutaneous Oncology. Dermatologic Surgery 1998, 24: 481-489. DOI: 10.1111/j.1524-4725.1998.tb04192.x.
- Jonason A, Kunala S, Price G, Restifo R, Spinelli H, Persing J, Leffell D, Tarone R, Brash D. Frequent clones of p53-mutated keratinocytes in normal human skin. Proceedings Of The National Academy Of Sciences Of The United States Of America 1996, 93: 14025-14029. PMID: 8943054, PMCID: PMC19488, DOI: 10.1073/pnas.93.24.14025.
- Gailani M, Ståhle-Bäckdahl M, Leffell D, Glyn M, Zaphiropoulos P, Undén A, Dean M, Brash D, Bale A, Toftgård R. The role of the human homologue of Drosophila patched in sporadic basal cell carcinomas. Nature Genetics 1996, 14: 78-81. PMID: 8782823, DOI: 10.1038/ng0996-78.
- Hahn H, Wicking C, Zaphiropoulos P, Gailani M, Shanley S, Chidambaram A, Vorechovsky I, Holmberg E, Unden A, Gillies S, Negus K, Smyth I, Pressman C, Leffell D, Gerrard B, Goldstein A, Dean M, Toftgard R, Chenevix-Trench G, Wainwright B, Bale A. Mutations of the Human Homolog of Drosophila patched in the Nevoid Basal Cell Carcinoma Syndrome. Cell 1996, 85: 841-851. PMID: 8681379, DOI: 10.1016/s0092-8674(00)81268-4.
- Ziegler A, Jonason A, Simon J, Leffell D, Brash DE. Tumor Suppressor Gene Mutations and Photocarcinogenesis. Photochemistry And Photobiology 1996, 63: 432-435. PMID: 8934758, DOI: 10.1111/j.1751-1097.1996.tb03064.x.
- Gailani M, Leffell D, Ziegler A, Gross E, Brash D, Bale A. Relationship Between Sunlight Exposure and a Key Genetic Alteration in Basal Cell Carcinoma. Journal Of The National Cancer Institute 1996, 88: 349-354. PMID: 8609643, DOI: 10.1093/jnci/88.6.349.
- Waldorf H, Kauvar A, Geronemus R, Leffell D. Remote fire with the pulsed dye laser: Risk and prevention. Journal Of The American Academy Of Dermatology 1996, 34: 503-506. PMID: 8609266, DOI: 10.1016/s0190-9622(96)90457-0.
- KOLENIK S, LEFFELL D. The Use of Cryopreserved Human Skin Allografts in Wound Healing following Mohs Surgery. Dermatologic Surgery 1995, 21: 615-620. PMID: 7606373, DOI: 10.1111/j.1524-4725.1995.tb00517.x.
- Bale A, Gailani M, Leffell D. The Gorlin syndrome gene: a tumor suppressor active in basal cell carcinogenesis and embryonic development. Proceedings Of The Association Of American Physicians 1995, 107: 253-7. PMID: 8624861.
- Morganroth G, Tigelaar R, Longley B, Luck L, Leffell D. Targetoid hemangioma associated with pregnancy and the menstrual cycle. Journal Of The American Academy Of Dermatology 1995, 32: 282-284. PMID: 7829718, DOI: 10.1016/0190-9622(95)90149-3.
- Bale A, Gailani M, Leffell D. Nevoid Basal Cell Carcinoma Syndrome. Journal Of Investigative Dermatology 1994, 103: s126-s130. DOI: 10.1038/jid.1994.23.
- Bale A, Gailani M, Leffell D. Nevoid basal cell carcinoma syndrome. Journal Of Investigative Dermatology 1994, 103: 126s-130s. PMID: 7963674, DOI: 10.1111/1523-1747.ep12399438.
- LEFFELL D, BERWICK M, BOLOGNIA J. The Effect of Pre‐Education on Patient Compliance with Full‐Body Examination in a Public Skin Cancer Screening. Dermatologic Surgery 1993, 19: 660-663. PMID: 8349904, DOI: 10.1111/j.1524-4725.1993.tb00407.x.
- Leffell D, Chen Y, Berwick M, Bolognia J. Interobserver agreement in a community skin cancer screening setting. Journal Of The American Academy Of Dermatology 1993, 28: 1003-1005. PMID: 8496441, DOI: 10.1016/s0190-9622(08)80653-6.
- Ziegler A, Leffell DJ, Kunala S, Sharma HW, Gailani M, Simon JA, Halperin AJ, Baden HP, Shapiro PE, Bale AE. Mutation hotspots due to sunlight in the p53 gene of nonmelanoma skin cancers. Proceedings Of The National Academy Of Sciences Of The United States Of America 1993, 90: 4216-4220. PMID: 8483937, PMCID: PMC46477, DOI: 10.1073/pnas.90.9.4216.
- Morganroth G, Leffell D. Nonexcisional Treatment of Benign and Premalignant Cutaneous Lesions. Clinics In Plastic Surgery 1993, 20: 91-104. PMID: 8420713, DOI: 10.1016/s0094-1298(20)30775-6.
- Leffell D, Thompson J. Lasers in Dermatology and Ophthalmology. Dermatologic Clinics 1992, 10: 687-700. PMID: 1395152, DOI: 10.1016/s0733-8635(18)30305-x.
- Developmental defects in gorlin syndrome related to a putative tumor suppressor gene on chromosome 9Gailani M, Bale S, Leffell D, DiGiovanna J, Peck G, Poliak S, Drum M, Pastakia B, McBride O, Kase R, Greene M, Mulvihill J, Bale A. Developmental defects in gorlin syndrome related to a putative tumor suppressor gene on chromosome 9. Cell 1992, 69: 111-117. PMID: 1348213, DOI: 10.1016/0092-8674(92)90122-s.
- Leffell DJ, Headington JT, Wong DS, Swanson NA. Aggressive-Growth Basal Cell Carcinoma in Young Adults. JAMA Dermatology 1991, 127: 1663-1667. PMID: 1952969, DOI: 10.1001/archderm.1991.01680100063005.
- Leffell D. An educational device for Mohs micrographic surgery. A three-dimensional model of basal cell carcinoma. Dermatologic Surgery 1991, 17: 498-501. PMID: 2040753.
- LEFFELL D, BROWN M, SWANSON N. Laser Vaporization: A Novel Treatment of Botryomycosis. Dermatologic Surgery 1989, 15: 703-705. PMID: 2501368, DOI: 10.1111/j.1524-4725.1989.tb03615.x.
- Leffell D, Stetz M, Milstone L, Deckelbaum L. In Vivo Fluorescence of Human Skin-Reply. JAMA Dermatology 1989, 125: 999-1000. DOI: 10.1001/archderm.1989.01670190133021.
- Leffell D, Stetz M, Milstone L, Deckelbaum L. In Vivo Fluorescence of Human Skin: A Potential Marker of Photoaging. JAMA Dermatology 1988, 124: 1514-1518. DOI: 10.1001/archderm.1988.01670100016005.
- Leffell DJ, Stetz ML, Milstone LM, Deckelbaum LI. In vivo fluorescence of human skin. A potential marker of photoaging. JAMA Dermatology 1988, 124: 1514-8. PMID: 3421727, DOI: 10.1001/archderm.124.10.1514.
- Leffell D, Braverman I. Familial multiple lipomatosis Report of a case and a review of the literature. Journal Of The American Academy Of Dermatology 1986, 15: 275-279. PMID: 3745530, DOI: 10.1016/s0190-9622(86)70166-7.
- Yale Dermatologic SurgeryTemple Medical Center40 Temple Street, Ste 5th Floor, Suite 5ANew Haven, CT 06510
- Yale Dermatologic SurgeryTemple Medical Center40 Temple Street, Ste 5th Floor, Suite 5ANew Haven, CT 06510