- Yale Physicians Building800 Howard Avenue, Fl Lower LevelNew Haven, CT 06519
Charles Matouk, MD
Biography
When he was a medical student, Charles Matouk, MD, met a patient with rapidly progressive dementia and weakness on the right side of his body. He recalls being “astonished” when the patient’s symptoms were fully reversed within a few weeks of having an endovascular procedure in his brain to disconnect an abnormal blood vessel (a vascular malformation) that had been causing the problem. The patient was cured. This experience was so memorable to Dr. Matouk that it inspired his decision to pursue a specialty in neurovascular surgery.
Now the chief of neurovascular surgery at Yale Medicine, Dr. Matouk has expertise in brain aneurysms, vascular malformations of the brain and spinal cord, carotid occlusive disease, acute stroke syndromes and adult-onset hydrocephalus. “In medicine today, a lot of the work that doctors do is either preventative or palliative,” Dr. Matouk remarks. “However, in neurosurgery we are able to use simple, minimally invasive procedures that can actually change everything for a patient. Their disease can be cured.”
As a surgeon, Dr. Matouk focuses on treating each patient as a person. “I hope that what I can provide patients is the opportunity to tell me their story and concerns,” he says. “It’s a partnership. My fundamental role is to help patients make an informed decision that’s right for them.” To help patients understand their conditions and treatment options, Dr. Matouk likes to show them the radiology pictures of their brain, and to sketch out what will happen during the procedure. He often encourages patients to go home and think about the information presented before making a decision to proceed.
In addition to caring for patients, Dr. Matouk is an assistant professor of neurosurgery and of radiology & biomedical imaging. He conducts clinical research on advanced imaging to help determine which aneurysms and vascular malformations are higher risk and should be prioritized for treatment, and which can be watched safely overtime.
Titles
- Associate Professor of Neurosurgery
- Vice Chair of Clinical Affairs, Neurosurgery
- Chief, Neurovascular Surgery
- Director, Neurovascular/Endovascular Fellowship
Education & Training
- FellowshipUniversity of Toronto (2011)
- ResidencyUniversity of Toronto (2009)
- MDUniversity of Calgary (1999)
- BSMcGill University (1996)
Languages Spoken
- English
- Français (French)
Additional Information
- McLaughlin Centre for Molecular Medicine Medical Scientist Training Fellowship: University of Toronto, Canada
- Canadian Institutes of Health Research (CIHR) Research Fellowship: Univeristy of Toronto, Canada
- American Association of Neurological Surgeons (AANS) / Neurosurgery Research & Education Foundation (NREF) Research Fellowship: University of Toronto, Canada
- Royal College of Physicians & Surgeons of CANADA, Neurological Surgery (2009)
- Sujijantarat N, Renedo D, Antonios J, Koo A, Amllay A, Nowicki K, Cord B, Hebert R, de Havenon A, Sheth K, Petersen N, Matouk C. Use of a dedicated open transcarotid access system for neurovascular disease. Journal Of NeuroInterventional Surgery 2024, jnis-2024-021599. PMID: 38719442, DOI: 10.1136/jnis-2024-021599.
- Amllay A, Owolo E, Nowicki K, Sujijantarat N, Koo A, Antonios J, Renedo D, Matouk C, Hebert R. Angiographic evidence of an inadvertent cannulation of the marginal sinus following central line migration: illustrative case. Journal Of Neurosurgery Case Lessons 2024, 7: case23607. PMID: 38684119, PMCID: PMC11058405, DOI: 10.3171/case23607.
- Olexa M, Begunova Y, Dhar R, Matouk C, Sheth K, Gutierrez S, De Havenon A, Petersen N. Quantitative Assessment of Reperfusion Impact on Cerebral Edema and Functional Outcomes in Large-vessel Occlusion Stroke Patients (S23.003). Neurology 2024, 102 DOI: 10.1212/wnl.0000000000205719.
- Olexa M, Begunova Y, Gilmore E, Kim J, Herman A, Beekman R, Magid-Bernstein J, Matouk C, Sheth K, Miller E, Gutierrez S, De Havenon A, Sansing L, Petersen N. Exploring the Relationship Between Cerebrospinal Fluid Interleukin-6 and Cerebral Autoregulation After Subarachnoid Hemorrhage (S23.004). Neurology 2024, 102 DOI: 10.1212/wnl.0000000000205692.
- Hawkes M, Clocchiatti-Tuozzo S, Rivier C, Qureshi A, Matouk C, Petersen N, De Havenon A, Sheth K, Falcone G. Different Response to Blood Pressure Reduction in Lobar and Deep Intracerebral Hemorrhage (P10-2.004). Neurology 2024, 102 DOI: 10.1212/wnl.0000000000206366.
- Jayasundara S, Kim J, Choi R, Rapuano A, Barnes E, Parasram M, Moura M, Uppal P, Chen Y, Top I, Olexa M, Maarek R, Yan J, Beekman R, Magid-Bernstein J, Hebert R, Bahrassa F, Matouk C, Sheth K, Gilmore E, Petersen N. Assessing Effects of Intrathecal Nicardipine on Cerebral Autoregulation and Cortical Activity in Aneurysmal Subarachnoid Hemorrhage (P10-5.019). Neurology 2024, 102 DOI: 10.1212/wnl.0000000000206285.
- Antonios J, Barak T, Gultekin B, Yalcin K, Adenu-Mensah N, Sujijantarat N, Koo A, Haynes J, Hebert R, Matouk C, Gunel M. 306 Endothelial Infiltrating Regulatory B Cells and NK T Cells Precipitate Inflammatory Cascade That Leads to Aneurysmal Rupture. Neurosurgery 2024, 70: 88-89. DOI: 10.1227/neu.0000000000002809_306.
- Sujijantarat N, Antonios J, Koo A, Haynes J, Renedo D, Hebert R, Sheth K, King J, Matouk C. 308 Improvement in Cranial Nerve Neuropathies Following Treatment of Intracranial Aneurysms With Flow Diverters: Institutional Outcomes and Meta-analysis of Literature. Neurosurgery 2024, 70: 89-89. DOI: 10.1227/neu.0000000000002809_308.
- de Havenon A, Zhou L, Koo A, Matouk C, Falcone G, Sharma R, Ney J, Shu L, Yaghi S, Kamel H, Sheth K. Endovascular Treatment of Acute Ischemic Stroke After Cardiac Interventions in the United States. JAMA Neurology 2024, 81: 264-272. PMID: 38285452, PMCID: PMC10825786, DOI: 10.1001/jamaneurol.2023.5416.
- Avery E, Abou-Karam A, Abi-Fadel S, Behland J, Mak A, Haider S, Zeevi T, Sanelli P, Filippi C, Malhotra A, Matouk C, Falcone G, Petersen N, Sansing L, Sheth K, Payabvash S. Radiomics-Based Prediction of Collateral Status from CT Angiography of Patients Following a Large Vessel Occlusion Stroke. Diagnostics 2024, 14: 485. PMID: 38472957, PMCID: PMC10930945, DOI: 10.3390/diagnostics14050485.
- Diogo C, Na D, Sujijantarat N, Matouk C, Callahan B. Diagnostic accuracy of intraoperative neuromonitoring in transcarotid artery revascularization. Journal Of NeuroInterventional Surgery 2024, jnis-2023-021282. PMID: 38378240, DOI: 10.1136/jnis-2023-021282.
- Renedo D, Rivier C, Koo A, Sujijantarat N, Clocchiatti-Tuozzo S, Wu K, Torres-Lopez V, Huo S, Gunel M, de Havenon A, Sheth K, Matouk C, Falcone G. APOE ε4 and Intracerebral Hemorrhage in Patients With Brain Arteriovenous Malformation. JAMA Network Open 2024, 7: e2355368. PMID: 38363572, PMCID: PMC10873768, DOI: 10.1001/jamanetworkopen.2023.55368.
- Hawkes M, Clocchiatti-Tuozzo S, Rivier C, Qureshi A, Matouk C, Petersen N, de Havenon A, Sheth K, Falcone G. Abstract 149: Different Response to Blood Pressure Reduction in Lobar and Deep Intracerebral Hemorrhage. Stroke 2024, 55 DOI: 10.1161/str.55.suppl_1.149.
- Petersen N, Olexa M, Jayasundara S, Falcone G, Gilmore E, Kim J, Matouk C, Alian A, Sheth K, Miller E, Ortega-Gutierrez S, de Havenon A. Abstract 51: Impact of Cerebral Autoregulation on the Relationship Between Blood Pressure Variability and Functional Outcome Following Endovascular Thrombectomy. Stroke 2024, 55 DOI: 10.1161/str.55.suppl_1.51.
- Renedo D, Rivier C, Clocchiatti-Tuozzo S, Huo S, Hebert R, Gunel M, Matouk C, Falcone G, Sheth K. Abstract HUP7: Impact of Social Determinants of Health and Academic Hospital Care on Outcomes After Non-Traumatic Subarachnoid Hemorrhage. Stroke 2024, 55 DOI: 10.1161/str.55.suppl_1.hup7.
- Vanent K, Rivier C, Matouk C, Levitt M, Leslie-Mazwi T, Gill T, Sheth K, Falcone G. Abstract WP159: Chronic Kidney Disease and Risk of Intracerebral Hemorrhage: The Role of Hypertension as a Mediator. Stroke 2024, 55 DOI: 10.1161/str.55.suppl_1.wp159.
- Olexa M, Begunova Y, Yan J, Herman A, Gilmore E, Kim J, Beekman R, Magid-Bernstein J, Matouk C, Sheth K, Miller E, Ortega-Gutierrez S, de Havenon A, Sansing L, Petersen N. Abstract WP152: Association Between Cerebrospinal Fluid Interleukin-6 Levels and Cerebral Autoregulation After Aneurysmal Subarachnoid Hemorrhage. Stroke 2024, 55 DOI: 10.1161/str.55.suppl_1.wp152.
- Olexa M, Begunova Y, Dhar R, Matouk C, Sheth K, Ortega-Gutierrez S, de Havenon A, Petersen N. Abstract 54: Investigating the Relationship Between Reperfusion and Cerebral Edema Using Novel Cerebrospinal Fluid and Net Water Uptake Biomarkers. Stroke 2024, 55 DOI: 10.1161/str.55.suppl_1.54.
- Sorby-Adams A, Guo J, Schleicher R, Mazurek M, Baldassano S, Payavbash S, Sze G, Schindler J, de Havenon A, Goldstein J, Schaefer P, Zabinska J, Lalwani D, Wira C, Matouk C, Lee V, Muir K, Nimjee S, Pinter N, Siddiqui A, Kirsch J, Iglesias J, Rosen M, Sheth K, Kimberly W. Abstract 89: Portable, Low-Field Magnetic Resonance Imaging: Determining Mismatch Following Acute Ischemic Stroke. Stroke 2024, 55 DOI: 10.1161/str.55.suppl_1.89.
- Ghannam M, AlMajali M, Khasiyev F, Dibas M, Qudah A, AlMajali F, Ghazaleh D, Shah A, Fayad F, Joudi K, Zaidat B, Childs C, Levy B, Abouainain Y, Brunschot D, Shu L, Goldstein E, Baig A, Roeder H, Henninger N, de Havenon A, Levy E, Matouk C, Derdeyn C, Leira E, Chaturvedi S, Yaghi S. Transcarotid Arterial Revascularization of Symptomatic Internal Carotid Artery Disease: A Systematic Review and Study-Level Meta-Analysis. Stroke 2024, 55: 921-930. PMID: 38299350, DOI: 10.1161/strokeaha.123.044246.
- Renedo D, Leasure A, Young R, Rivier C, Alhanti B, Grory B, Messe S, Reeves M, Hassan A, Schwamm L, de Havenon A, Matouk C, Sheth K, Falcone G. COVID‐19 Infection Is Associated With Poor Outcomes in Patients With Intracerebral Hemorrhage. Journal Of The American Heart Association 2024, 13: e030999. PMID: 38293940, PMCID: PMC11056169, DOI: 10.1161/jaha.123.030999.
- Prasad A, Gilmore E, Kim J, Begunova L, Olexa M, Beekman R, Falcone G, Matouk C, Ortega-Gutierrez S, Temkin N, Barber J, Diaz-Arrastia R, de Havenon A, Petersen N. Impact of Therapeutic Interventions on Cerebral Autoregulatory Function Following Severe Traumatic Brain Injury: A Secondary Analysis of the BOOST-II Study. Neurocritical Care 2023, 1-9. PMID: 38158481, DOI: 10.1007/s12028-023-01896-x.
- Orscelik A, Matsukawa H, Elawady S, Sowlat M, Cunningham C, Zandpazandi S, Kasem R, Maier I, Jabbour P, Kim J, Wolfe S, Rai A, Starke R, Psychogios M, Shaban A, Goyal N, Yoshimura S, Cuellar H, Howard B, Alawieh A, Romano D, Tanweer O, Mascitelli J, Fragata I, Polifka A, Osbun J, Crosa R, Matouk C, Park M, Levitt M, Brinjikji W, Moss M, Dumont T, Williamson R, Navia P, Kan P, De Leacy R, Chowdhry S, Ezzeldin M, Spiotta A, Kasab S, Collaborators S. Comparative Outcomes of Mechanical Thrombectomy in Acute Ischemic Stroke Patients with ASPECTS 2-3 vs. 4-5. Journal Of Stroke And Cerebrovascular Diseases 2023, 33: 107528. PMID: 38134550, DOI: 10.1016/j.jstrokecerebrovasdis.2023.107528.
- Clouse J, Thaci B, Clark A, Baggett M, Raslan O, Matouk C, Waldau B, Cord B. Successful mechanical thrombectomy for terminal ICA bullet embolism: A case report. Interventional Neuroradiology 2023, 15910199231219021. PMID: 38073079, DOI: 10.1177/15910199231219021.
- Ash M, Dimisko L, Chalhoub R, Howard B, Cawley C, Matouk C, Pabaney A, Spiotta A, Jabbour P, Maier I, Wolfe S, Rai A, Kim J, Psychogios M, Mascitelli J, Starke R, Shaban A, Yoshimura S, De Leacy R, Kan P, Fragata I, Polifka A, Arthur A, Park M, Crosa R, Williamson R, Dumont T, Levitt M, Kasab S, Tjoumakaris S, Liman J, Saad H, Samaniego E, Fargen K, Grossberg J, Alawieh A. Comprehensive analysis of the impact of procedure time and the ‘golden hour’ in subpopulations of stroke thrombectomy patients. Journal Of NeuroInterventional Surgery 2023, jnis-2023-020792. PMID: 37875342, DOI: 10.1136/jnis-2023-020792.
- Mazurek M, Parasuram N, Peng T, Beekman R, Yadlapalli V, Sorby-Adams A, Lalwani D, Zabinska J, Gilmore E, Petersen N, Falcone G, Sujijantarat N, Matouk C, Payabvash S, Sze G, Schiff S, Iglesias J, Rosen M, de Havenon A, Kimberly W, Sheth K. Detection of Intracerebral Hemorrhage Using Low-Field, Portable Magnetic Resonance Imaging in Patients With Stroke. Stroke 2023, 54: 2832-2841. PMID: 37795593, PMCID: PMC11103256, DOI: 10.1161/strokeaha.123.043146.
- Vranic J, Harker P, Stapleton C, Regenhardt R, Dmytriw A, Doron O, Alotaibi N, Leslie-Mazwi T, Gupta R, Berglar I, Tan C, Koch M, Raymond S, Mascitelli J, Patterson T, Seinfeld J, White A, Case D, Roark C, Gandhi C, Al-Mufti F, Cooper J, Matouk C, Sujijantarat N, Devia D, Ocampo-Navia M, Villamizar-Torres D, Puentes J, Patel A. The Impact of Dual Antiplatelet Therapy Duration on Unruptured Aneurysm Occlusion After Flow Diversion: A Multicenter Study. Journal Of Computer Assisted Tomography 2023, 47: 753-758. PMID: 37707405, DOI: 10.1097/rct.0000000000001457.
- Antonios J, Barak T, Gultekin B, Yalcin K, Chamberlain A, Hebert R, Matouk C, Gunel M. O-068 Regulatory B cell and adjunctive immune population drives intracranial aneurysm rupture in patient population. 2023, a53.1-a53. DOI: 10.1136/jnis-2023-snis.68.
- Renedo D, Acosta J, Koo A, Rivier C, Sujijantarat N, de Havenon A, Sharma R, Gill T, Sheth K, Falcone G, Matouk C. Higher Hospital Frailty Risk Score Is Associated With Increased Risk of Stroke: Observational and Genetic Analyses. Stroke 2023, 54: 1538-1547. PMID: 37216451, PMCID: PMC10212531, DOI: 10.1161/strokeaha.122.041891.
- Olexa M, Begunova Y, Bartolome D, Peng T, Matouk C, Sheth K, Petersen N. Investigating the Relationship Between Oximetry Trends During Endovascular Therapy and Neurological Worsening for Patients with Acute Ischemic Stroke (S24.006). Neurology 2023, 100 DOI: 10.1212/wnl.0000000000202997.
- Siddiqui A, Monteiro A, Hanel R, Kan P, Mohanty A, Cortez G, Rabinovich M, Matouk C, Sujijantarat N, Romero C, Stone J, Ebersole K, Fry L, Natarajan S, Thomson B, Ortega-Gutierrez S, Vivanco-Suarez J, Wakhloo A, Levy E. 482 Triple Therapy Versus Dual Antiplatelet Therapy for Dolichoectatic Vertebrobasilar Fusiform Aneurysms Treated With Flow Diverters: The Last Frontier? Neurosurgery 2023, 69: 103-104. DOI: 10.1227/neu.0000000000002375_482.
- Khan A, Khunte M, Wu X, Bajaj S, Payabvash S, Wintermark M, Matouk C, Seidenwurm D, Gandhi D, Parizel P, Mezrich J, Malhotra A. Malpractice Litigation Related to Diagnosis and Treatment of Intracranial Aneurysms. American Journal Of Neuroradiology 2023, 44: 460-466. PMID: 36997286, PMCID: PMC10084911, DOI: 10.3174/ajnr.a7828.
- Hong C, Marianayagam N, Morales-Valero S, Barak T, Tabor J, O’Brien J, Huttner A, Baehring J, Gunel M, Erson-Omay E, Fulbright R, Matouk C, Moliterno J. Vascular steal and associated intratumoral aneurysms in highly vascular brain tumors: illustrative case. Journal Of Neurosurgery Case Lessons 2023, 5: case22512. PMID: 36880509, PMCID: PMC10550659, DOI: 10.3171/case22512.
- Ammar A, Elsamadicy A, Ammar M, Reeves B, Koo A, Falcone G, Hwang D, Petersen N, Kim J, Beekman R, Prust M, Magid-Bernstein J, Acosta J, Herbert R, Sheth K, Matouk C, Gilmore E. Emergent external ventricular drain placement in patients with factor Xa inhibitor-associated intracerebral hemorrhage after reversal with andexanet alfa. Clinical Neurology And Neurosurgery 2023, 226: 107621. PMID: 36791588, DOI: 10.1016/j.clineuro.2023.107621.
- Renedo D, Rivier C, Acosta J, Clocchiatti S, Wu K, Torres-Lopez V, Sheth K, Gunel M, Matouk C, Falcone G. Abstract 51: Apoe Epsilon 4 And Risk Of Bleeding Patients With Brain Arteriovenous Malformations. A Combined Genetic Study In The Uk Biobank And All Of Us. Stroke 2023, 54: a51-a51. DOI: 10.1161/str.54.suppl_1.51.
- Clocchiatti-Tuozzo S, Renedo D, Rivier C, Lopez V, Matouk C, Sheth K, Gill T, Falcone G. Abstract HUP6: Community Deprivation And Healthcare Access/Utilization In Patients With Carotid Stenosis: Results From The All Of Us Research Program. Stroke 2023, 54: ahup6-ahup6. DOI: 10.1161/str.54.suppl_1.hup6.
- Clocchiatti-Tuozzo S, Renedo D, Rivier C, Lopez V, Matouk C, Sheth K, Gill T, Falcone G. Abstract WMP75: Community Deprivation And Healthcare Access/Utilization In Patients With Carotid Stenosis: Results From The All Of UsResearch Program. Stroke 2023, 54: awmp75-awmp75. DOI: 10.1161/str.54.suppl_1.wmp75.
- Renedo D, Leasure A, Acosta J, Young R, Alhanti B, Grory B, Spudich S, Messe S, Reeves M, Hassan A, Schwamm L, Matouk C, Sheth K, Falcone G. Abstract WP130: Intracerebral Hemorrhage Outcomes And Trends During The Covid-19 Pandemic. An Observational Study Of 61,417 Cases. Stroke 2023, 54: awp130-awp130. DOI: 10.1161/str.54.suppl_1.wp130.
- Olexa M, Begunova Y, Bartolome D, Peng T, Sheth K, Matouk C, Petersen N. Abstract 11: Identifiable Patterns Of Noninvasive Cerebral Oximetry During Endovascular Therapy For Acute Ischemic Stroke Are Associated With Neurological Deterioration. Stroke 2023, 54: a11-a11. DOI: 10.1161/str.54.suppl_1.11.
- Parasuram N, Crawford A, Mazurek M, Chavva I, Beekman R, Gilmore E, Petersen N, Payabvash S, Sze G, Eugenio Iglesias J, Omay S, Matouk C, Longbrake E, de Havenon A, Schiff S, Rosen M, Kimberly W, Sheth K. Future of Neurology & Technology: Neuroimaging Made Accessible Using Low-Field, Portable MRI. Neurology 2023, 100: 1067-1071. PMID: 36720639, PMCID: PMC10259275, DOI: 10.1212/wnl.0000000000207074.
- Koo A, Elsamadicy A, Matouk C. In Reply to the Letter to Editor Regarding "Hospital Frailty Risk Score Predicts Adverse Events and Readmission Following Ventriculoperitoneal Shunt Surgery for Normal Pressure Hydrocephalus". World Neurosurgery 2023, 169: 124. PMID: 36585096, DOI: 10.1016/j.wneu.2022.11.023.
- Koo A, Elsamadicy A, Renedo D, Matouk C. Response to letter to the Editor on ‘Utility of the Hospital Frailty Risk Score in patients undergoing endovascular treatment for ruptured aneurysms’. Journal Of NeuroInterventional Surgery 2022, 15: 307-308. PMID: 36319084, DOI: 10.1136/jnis-2022-019708.
- Ackerman-Banks C, Fardelmann K, Lam D, Simmons M, Elder R, Matouk C, Campbell K. Unrepaired Maternal Vein of Galen Malformation in Pregnancy: A Case Report. A&A Practice 2022, 16: e01634. PMID: 36599040, DOI: 10.1213/xaa.0000000000001634.
- Siddiqui A, Monteiro A, Hanel R, Kan P, Mohanty A, Cortez G, Rabinovich M, Matouk C, Sujijantarat N, Ebersole K, Fry L, Natarajan S, Owusu-Adjei B, Ortega-Gutierrez S, Vivanco-Suarez J, Wakhloo A, Levy E. P-017 Triple therapy versus dual antiplatelet therapy for dolichoectatic vertebrobasilar fusiform aneurysms treated with flow-diverters: the last frontier? 2022, a59.1-a59. DOI: 10.1136/neurintsurg-2022-snis.89.
- Bartolome D, Begunova Y, Prasad A, Soto A, Kobsa J, Top I, Quispe-Orozco D, Farooqui M, Zevallos C, Kim J, Gilmore E, Beekman R, De Havenon A, Matouk C, Sheth K, Ortega-Gutiérrez S, Petersen N. Cerebral hypoperfusion after nimodipine administration is associated with worse functional outcomes in subarachnoid hemorrhage patients (P6-7.001). Neurology 2022, 98 DOI: 10.1212/wnl.98.18_supplement.3609.
- Begunova Y, Bartolome D, Kobsa J, Soto A, Prasad A, Galecio M, Vivanco-Suarez J, Quispe-Orozco D, Farooqui M, Sansing L, Schindler J, De Havenon A, Matouk C, Sheth K, Ortega-Gutierrez S, Petersen N. Poor Collaterals and Rapid Early Infarct Progression Are Associated With Increased Vulnerability to Blood Pressure Reductions (S21.002). Neurology 2022, 98 DOI: 10.1212/wnl.98.18_supplement.3104.
- Prasad A, Kobsa J, Soto A, Bartolome D, Begunova L, Kim J, Gilmore E, Sheth K, Matouk C, De Havenon A, Diaz-Arrastia R, Petersen N. Cerebral Autoregulatory Function Before, During, and After Therapeutic Interventions Following Severe Traumatic Brain Injury: A Secondary Analysis of the BOOST-II Study (S21.001). Neurology 2022, 98 DOI: 10.1212/wnl.98.18_supplement.557.
- Top I, Chen Y, Bartolome D, Rapuano A, Gilmore E, Sheth K, Matouk C, Petersen N, Kim J. Impaired Cerebral Autoregulation Related Blood Pressure Reductions After Nimodipine Are Associated with Ischemic Changes on EEG After Subarachnoid Hemorrhage (P13-10.002). Neurology 2022, 98 DOI: 10.1212/wnl.98.18_supplement.3539.
- Koo A, Elsamadicy A, Sarkozy M, Sherman J, Reeves B, Freedman I, Antonios J, Sujijantarat N, Renado D, Hebert R, Malhotra A, Matouk C. 307 The Hospital Frailty Risk Score Independently Predicts Increased Complication Rates and Healthcare Resource Utilization After Endovascular Treatment of Ruptured Aneurysms. Neurosurgery 2022, 68: 67-68. DOI: 10.1227/neu.0000000000001880_307.
- Bartolome D, Begunova Y, Prasad A, Soto A, Kobsa J, Top I, Quispe-Orozco D, Farooqui M, Zevallos C, Kim J, Gilmore E, Beekman R, de Havenon A, Matouk C, Sheth K, Ortega-Gutierrez S, Petersen N. Abstract 89: Nimodipine-induced Blood Pressure Reductions Below Personalized Limits Of Autoregulation Are Associated With Worse Outcomes After Subarachnoid Hemorrhage. Stroke 2022, 53: a89-a89. DOI: 10.1161/str.53.suppl_1.89.
- Vanent K, Acosta J, Both C, Leasure A, Noche R, Levitt M, Matouk C, Gunel M, Sheth K, Falcone G. Abstract 105: Polygenic Burden Of Hypertension-related Alleles Leads To Non-traumatic Subarachnoid Hemorrhage At Younger Ages. Stroke 2022, 53: a105-a105. DOI: 10.1161/str.53.suppl_1.105.
- Renedo D, Acosta J, Sheth K, Matouk C, Falcone G. Abstract 123: Carotid Artery Stenosis In Underrepresented Populations Defined By Factors Other Than Race/ethnicity: Results From All Of Us. Stroke 2022, 53: a123-a123. DOI: 10.1161/str.53.suppl_1.123.
- Atillasoy J, Leasure A, Schwartz A, Reznik M, Moody S, Bevers M, Matouk C, Falcone G, Sansing L, Kimberly W, Sheth K. Abstract TP134: Association Of Neutrophil-lymphocyte Ratio With Functional Outcome In Spontaneous Intracerebral Hemorrhage. Stroke 2022, 53: atp134-atp134. DOI: 10.1161/str.53.suppl_1.tp134.
- Choi J, Saver J, Nogueira R, Poli S, Nguyen T, Chen M, Matouk C, Pile-Spellman J. Hybernia post-mechanical thrombectomy – Endovascular cerebral hypothermia trial in acute ischemic stroke (post-mtech trial). Journal Of The Neurological Sciences 2021, 429: 119718. DOI: 10.1016/j.jns.2021.119718.
- Wu X, Wira C, Matouk C, Forman H, Gandhi D, Sanelli P, Schindler J, Malhotra A. Drip-and-ship versus mothership for endovascular treatment of acute stroke: A comparative effectiveness analysis. International Journal Of Stroke 2021, 17: 315-322. PMID: 33759645, DOI: 10.1177/17474930211008701.
- Acosta J, Szejko N, Lopez V, Both C, Sansing L, Sheth K, Matouk C, Falcone G. Klotho-VS Heterozygosity is Associated with Lower Risk of Non-traumatic Subarachnoid Hemorrhage (2737). Neurology 2021, 96 DOI: 10.1212/wnl.96.15_supplement.2737.
- Peshwe K, Nguyen C, Kodali S, Kobsa J, Prasad A, Soto A, Wira C, Matouk C, Sheth K, Petersen N. Abstract MP36: Blood Pressure Reductions in the Hyperacute Phase of Large Vessel Occlusion Ischemic Stroke Are Associated With Infarct Progression and Poor Functional Outcome. Stroke 2021, 52 DOI: 10.1161/str.52.suppl_1.mp36.
- Koo A, Elsamadicy A, Lin I, David W, Reeves B, Santarosa C, Cord B, Malhotra A, Kahle K, Matouk C. Patient Risk Factors Associated with 30- and 90- Day Readmission after Ventriculoperitoneal Shunt Placement for Idiopathic Normal Pressure Hydrocephalus in Elderly Patients. Neurosurgery 2020, 67 DOI: 10.1093/neuros/nyaa447_202.
- Koo A, Elsamadicy A, Lin I, David W, Freedman I, Sujijantarat N, Cord B, Hebert R, Bahrassa F, Malhotra A, Matouk C. Predictors of Extended Length of Stay following Treatment of Unruptured Adult Cerebral Aneurysms. Neurosurgery 2020, 67 DOI: 10.1093/neuros/nyaa447_147.
- Robert S, Matouk C. Stem Cell Therapy for Stroke. 2020, 331-345. DOI: 10.1007/978-3-030-56954-9_15.
- Matouk C, Cord B. Vascular Malformations of the Brain and Spine. 2020, 177-191. DOI: 10.1007/978-3-030-52552-1_14.
- Nguyen C, Silverman A, Wang A, Kodali S, Strander S, Kimmel A, Peshwe K, de Havenon A, Gilmore E, Sansing L, Schindler J, Matouk C, Sheth K, Petersen N. Risk of Worse Outcome in Stroke Patients with High Blood Pressure Variability After Endovascular Thrombectomy May Be Amplified by Impaired Cerebral Autoregulation (4457). Neurology 2020, 94 DOI: 10.1212/wnl.94.15_supplement.4457.
- Cahn B, Shah J, Dyvorne H, O’Halloran R, Poole M, Yuen M, Mazurek M, Ward A, Payabvash S, Beekman R, Brown S, Falcone G, Gobeske K, Petersen N, Jasne A, Sharma R, Schindler J, Sansing L, Gilmore E, Wira C, Matouk C, Sze G, Rosen M, Kimberly W, Sheth K. Deployment of Portable, Bedside, Low-field Magnetic Resonance Imaging for Evaluation of Stroke Patients (272). Neurology 2020, 94 DOI: 10.1212/wnl.94.15_supplement.272.
- Kuohn L, Leasure A, Acosta J, Vanent K, Murthy S, Kamel H, Matouk C, Sansing L, Falcone G, Sheth K. Causes of Death in a Longitudinal Analysis of Spontaneous Intracerebral Hemorrhage Survivors (4228). Neurology 2020, 94 DOI: 10.1212/wnl.94.15_supplement.4228.
- Acosta J, Both C, Brown S, Leasure A, Vanent K, Noche R, Kirsch E, Petersen N, Matouk C, Gunel M, Gill T, Sheth K, Falcone G. Abstract 66: Causal Associations Between Genetically-determined Smoking and Risk of Subarachnoid Hemorrhage. Stroke 2020, 51 DOI: 10.1161/str.51.suppl_1.66.
- Silverman A, Wang A, Kodali S, Strander S, Kimmel A, Nguyen C, Peshwe K, Matouk C, Kimberly W, Sheth K, Tan C, Petersen N. Abstract TP417: An Autoregulation-Derived Prediction Model for Midline Shift After Ischemic Stroke. Stroke 2020, 51 DOI: 10.1161/str.51.suppl_1.tp417.
- Silverman A, Kodali S, Strander S, Gilmore E, Kimmel A, Wang A, Cord B, Falcone G, Hebert R, Matouk C, Sheth K, Petersen N. Deviation from Dynamic and Personalized Optimal Blood Pressure Targets is Associated With Worse Functional Outcomes After Aneurysmal Subarachnoid Hemorrhage. Neurosurgery 2019, 66: 310-186. DOI: 10.1093/neuros/nyz310_186.
- Cord B, Wang A, Chouairi F, Koo A, Porto C, Silverman A, Kodali S, Strander S, Falcone G, Sheth K, Hebert R, Sansing L, Schindler J, Petersen N, Matouk C. Percutaneous Trans-Carotid Puncture for Mechanical Thrombectomy in Acute Ischemic Stroke Patients is Safe and Effective: A Large, Single-Center Case Series. Neurosurgery 2019, 66: 310-167. DOI: 10.1093/neuros/nyz310_167.
- Cord B, Santarosa C, Sujijantarat N, Kundishora A, Falcone G, Sheth K, Sansing L, Schindler J, Petersen N, Matouk C. Preliminary Experience With Proximal Flow Reversal During Intracranial Balloon Angioplasty and Stenting for Symptomatic, Severe Intracranial Stenosis. Neurosurgery 2019, 66: 310-675. DOI: 10.1093/neuros/nyz310_675.
- Wu X, Gandhi D, Matouk C, Schindler J, Hughes D, Forman H, Sanelli P, Malhotra A. Implications of Achieving TICI 2b Versus TICI 3 Reperfusion in Patients With Ischemic Stroke: A Cost-Effectiveness Analysis. Neurosurgery 2019, 66: 310-670. DOI: 10.1093/neuros/nyz310_670.
- Silverman A, Wang A, Kodali S, Strander S, Cord B, Hebert R, Matouk C, Gilmore E, Sheth K, Petersen N. Abstract 147: Individualized Blood Pressure Management After Subarachnoid Hemorrhage Using Real-time Autoregulation Monitoring: A Pilot Study Using NIRS and ICP-derived Limits of Autoregulation. Stroke 2019, 50 DOI: 10.1161/str.50.suppl_1.147.
- Littauer R, Sather J, Rothenberg C, Finn E, Yip M, Matouk C, Pham L, Sheth K, Ulrich A, Parwani Y, Venkatesh A. 57 Improving the Safety and Quality of Inter-Hospital Transfer for Nontraumatic Intracerebral and Subarachnoid Hemorrhage. Annals Of Emergency Medicine 2018, 72: s25-s26. DOI: 10.1016/j.annemergmed.2018.08.062.
- Mandell D, Mossa-Basha M, Qiao Y, Hess C, Hui F, Matouk C, Johnson M, Daemen M, Vossough A, Edjlali M, Saloner D, Ansari S, Wasserman B, Mikulis D. Intracranial vessel wall MRI: Principles and expert consensus Recommendations of the American Society of Neuroradiology. International Journal Of Cerebrovascular Diseases 2018, 26: 641-653. DOI: 10.3760/cma.j.issn.1673-4165.2018.09.001.
- Wu X, Matouk C, Malhotra A. 316 Screening for Intracranial Aneurysms in Patients With Autosomal Dominant Polycystic Kidney Disease. Neurosurgery 2018, 65: 128. DOI: 10.1093/neuros/nyy303.316.
- Wu X, Cord B, Sommaruga S, Matouk C, Malhotra A. 315 Comparative Effectiveness Analysis of Pipeline Embolization Device versus Coiling in Unruptured Aneurysms Less Than 10 mm in Size. Neurosurgery 2018, 65: 127-128. DOI: 10.1093/neuros/nyy303.315.
- Wu X, Cord B, Sommaruga S, Matouk C, Malhotra A. 148 Management of Unruptured Intracranial Aneurysms in the Elderly. Neurosurgery 2018, 65: 97. DOI: 10.1093/neuros/nyy303.148.
- Mampre D, Wang A, Sheth K, Tan C, Hebert R, Matouk C, Petersen N. 105 Decreases in Blood Pressure During Endovascular Stroke Therapy Are Common and Associated With Poor Functional Outcome. Neurosurgery 2018, 65: 82. DOI: 10.1093/neuros/nyy303.105.
- Adeeb N, Griessenauer C, Dmytriw A, Shallwani H, Gupta R, Foreman P, Shakir H, Moore J, Limbucci N, Mangiafico S, Kumar A, Michelozzi C, Zhang Y, Pereira V, Matouk C, Harrigan M, Siddiqui A, Levy E, Renieri L, Marotta T, Cognard C, Ogilvy C, Thomas A. Risk of Branch Occlusion and Ischemic Complications with the Pipeline Embolization Device in the Treatment of Posterior Circulation Aneurysms. American Journal Of Neuroradiology 2018, 39: 1303-1309. PMID: 29880475, PMCID: PMC7655425, DOI: 10.3174/ajnr.a5696.
- Sommaruga S, Cord B, Santarosa C, Yeung J, Johnson M, Hebert R, Bijlenga P, Schaller K, Matouk C. High-Resolution Vessel Wall MRI in Ruptured Cranial Dural Arteriovenous Fistulas. Journal Of Neurological Surgery Part A Central European Neurosurgery 2018, 79: s1-s27. DOI: 10.1055/s-0038-1660759.
- Sommaruga S, Chu S, Hwang D, Dearborn J, Sansing L, Cord B, Santarosa C, Samarth G, Petersen N, Gilmore E, Schindler J, Bijlenga P, Schaller K, Matouk C, Sheth K, Falcone G. History of Intracranial Hemorrhage Is Associated with In-Hospital Mortality in Ischemic Stroke Patients Treated with Intravenous Thrombolytics. Journal Of Neurological Surgery Part A Central European Neurosurgery 2018, 79: s1-s27. DOI: 10.1055/s-0038-1660745.
- Sommaruga S, Beekman R, Chu S, King Z, Matouk C, Hwang D, Sheth K, Falcone G. Spontaneous Intracerebral Hemorrhage in the Elderly Population. Journal Of Neurological Surgery Part A Central European Neurosurgery 2018, 79: s1-s27. DOI: 10.1055/s-0038-1660768.
- Sommaruga S, Cord B, Santarosa C, Malhotra A, Jonhson M, Sheth K, Gunel M, Herbert R, Bijlenga P, Schaller K, Falcone G, Matouk C. Predictors of Vessel Wall Enhancement in Unruptured Intracranial Aneurysms. Journal Of Neurological Surgery Part A Central European Neurosurgery 2018, 79: s1-s27. DOI: 10.1055/s-0038-1660769.
- Sommaruga S, Cord B, Minja F, Malhotra A, Johnson M, Bijlenga P, Schaller K, Matouk C. High-Resolution MRI with Black Blood Sequence Increases Physician Confidence in Identification of Rupture Site in Cerebral AVMs: Application to Treatment Strategies. Journal Of Neurological Surgery Part A Central European Neurosurgery 2018, 79: s1-s27. DOI: 10.1055/s-0038-1660760.
- Sommaruga S, Cord B, Molhotra A, Johnson M, Minja F, Gunel M, Sheth K, Herbert R, Melnikov F, Schaller K, Mandell D, Bijlenga P, Falcone G, Matouk C. Abstract WMP31: Vessel Wall Enhancement is Associated With Clinical and Imaging Markers of Aneurysm Instability. Stroke 2018, 49 DOI: 10.1161/str.49.suppl_1.wmp31.
- Wang A, Mampre D, Sheth K, Tan C, Matouk C, Hebert R, Petersen N. Abstract WP320: Blood Pressure Reduction During Endovascular Stroke Therapy is Associated With Poor Functional Outcome. Stroke 2018, 49 DOI: 10.1161/str.49.suppl_1.wp320.
- Saba L, Yuan C, Hatsukami T, Balu N, Qiao Y, DeMarco J, Saam T, Moody A, Li D, Matouk C, Johnson M, Jäger H, Mossa-Basha M, Kooi M, Fan Z, Saloner D, Wintermark M, Mikulis D, Wasserman B. Carotid Artery Wall Imaging: Perspective and Guidelines from the ASNR Vessel Wall Imaging Study Group and Expert Consensus Recommendations of the American Society of Neuroradiology. American Journal Of Neuroradiology 2018, 39: e9-e31. PMID: 29326139, PMCID: PMC7410574, DOI: 10.3174/ajnr.a5488.
- Yip M, Sather J, Sheth K, Matouk C, Littauer R, Finn E, Rothenberg C, Costello D, Parwani V, Venkatesh A. 295 Interhospital Transfer is Not a Predictor of In-Hospital Mortality for Patients With Nontraumatic Intracranial Hemorrhage. Annals Of Emergency Medicine 2017, 70: s116-s117. DOI: 10.1016/j.annemergmed.2017.07.273.
- Cord B, Sommaruga S, Hebert R, Malhotra A, Johnson M, Minja F, Gunel M, Sheth K, Falcone G, Matouk C. 168 Wall Enhancement in Unruptured Aneurysms is Associated with Symptomatic Presentation and Size. Neurosurgery 2017, 64: 243. DOI: 10.1093/neuros/nyx417.168.
- White J, Matouk C. Aneurysmal Subarachnoid Hemorrhage. 2017, 55-74. DOI: 10.1007/978-3-319-48669-7_4.
- O-021 Pipeline embolization of posterior circulation aneurysms: a multicenter study of 131 aneurysmsGriessenauer C, Ogilvy C, Adeeb N, Dmytriw A, Foreman P, Shallwani H, Limbucci N, Mangiafico S, Kumar A, Michelozzi C, Krings T, Pereira V, Matouk C, Harrigan M, Shakir H, Siddiqui A, Levy E, Renieri L, Marotta T, Cognard C, Thomas A. O-021 Pipeline embolization of posterior circulation aneurysms: a multicenter study of 131 aneurysms. Journal Of NeuroInterventional Surgery 2017, 9: a13. DOI: 10.1136/neurintsurg-2017-snis.21.
- Dmytriw, Adeeb N, Kumar A, Griessenauer C, Ogilvy C, Foreman P, Shallwani H, Limbucci N, Mangiafico S, Michelozzi C, Krings T, Pereira V, Matouk C, Zhang Y, Harrigan M, Phan K, Shakir H, Siqqiqui A, Levy E, Renieri L, Cognard C, Thomas A, Marotta T. O-018 Flow diversion for the treatment of basilar apex aneurysms. Journal Of NeuroInterventional Surgery 2017, 9: a11. DOI: 10.1136/neurintsurg-2017-snis.18.
- Cord B, Sommaruga S, Yeung J, Johnson M, Matouk C. E-050 First-Line Treatment by Embolization with Intention-to-Cure in the Management of Cranial Dural Arteriovenous Fistulas. Journal Of NeuroInterventional Surgery 2016, 8: a70. DOI: 10.1136/neurintsurg-2016-012589.122.
- Malhotra A, Wu X, Kalra V, Matouk C, Forman H. Regarding “Clinical and Imaging Follow-Up of Patients with Coiled Basilar Tip Aneurysms Up to 20 Years”. American Journal Of Neuroradiology 2016, 37: e39-e39. PMID: 26822726, PMCID: PMC7960187, DOI: 10.3174/ajnr.a4708.
- Coutinho J, Sacho R, Schaafsma J, Agid R, Krings T, Radovanovic I, Matouk C, Mikulis D, Mandell D. High-Resolution Vessel Wall Magnetic Resonance Imaging in Angiogram-Negative Non-Perimesencephalic Subarachnoid Hemorrhage. Clinical Neuroradiology 2015, 27: 175-183. PMID: 26608742, DOI: 10.1007/s00062-015-0484-x.
- Bulsara K, Grant R, Matouk C. Practical Microsurgical and Endovascular Treatment of Vasospasm. 2015, 75-75. DOI: 10.5005/jp/books/12423_12.
- Matouk CC, Mandell DM, Günel M, Bulsara KR, Malhotra A, Hebert R, Johnson MH, Mikulis DJ, Minja FJ. Vessel Wall Magnetic Resonance Imaging Identifies the Site of Rupture in Patients With Multiple Intracranial AneurysmsProof of Principle. Neurosurgery 2013, 72: 492-496. PMID: 23151622, DOI: 10.1227/neu.0b013e31827d1012.
- Marsden P, Matouk C, Turgeon P. Epigenetics and stroke risk – beyond the static DNA code. Advances In Genomics And Genetics 2012, Volume 2: 67-84. DOI: 10.2147/agg.s18697.
- Matouk CC, Kaderali Z, terBrugge KG, Willinsky RA. Long-Term Clinical and Imaging Follow-Up of Complex Intracranial Aneurysms Treated by Endovascular Parent Vessel Occlusion. American Journal Of Neuroradiology 2012, 33: 1991-1997. PMID: 22555575, PMCID: PMC7964607, DOI: 10.3174/ajnr.a3079.
- Alkins R, Matouk CC, Cruz JP, Marotta T, Montanera W, Spears J. Carotid Artery Angioplasty and Stenting for Patients Less than 70 Years-of-Age. Canadian Journal Of Neurological Sciences / Journal Canadien Des Sciences Neurologiques 2012, 39: 338-342. PMID: 22547514, DOI: 10.1017/s0317167100013470.
- Martin AR, Cruz JP, Matouk CC, Spears J, Marotta TR. The Pipeline Flow-Diverting Stent for Exclusion of Ruptured Intracranial Aneurysms With Difficult Morphologies. Neurosurgery 2012, 70: ons21-ons28. PMID: 21841519, DOI: 10.1227/neu.0b013e3182315ee3.
- Mandell DM, Matouk CC, Farb RI, Krings T, Agid R, terBrugge K, Willinsky RA, Swartz RH, Silver FL, Mikulis DJ. Vessel Wall MRI to Differentiate Between Reversible Cerebral Vasoconstriction Syndrome and Central Nervous System Vasculitis. Stroke 2011, 43: 860-862. PMID: 22156692, DOI: 10.1161/strokeaha.111.626184.
- Matouk C, Hanbidge A, Mandell D, Terbrugge K, Agid R. Osteogenesis Imperfecta, Multiple Intra-Abdominal Arterial Dissections and a Ruptured Dissecting-Type Intracranial Aneurysm. Interventional Neuroradiology 2011, 17: 371-375. PMID: 22005702, PMCID: PMC3396044, DOI: 10.1177/159101991101700315.
- Ebinu J, Matouk C, Wallace M, Terbrugge K, Krings T. Hydrocephalus Secondary to Hydrodynamic Disequilibrium in an Adult Patient with a Choroidal-Type Arteriovenous Malformation. Interventional Neuroradiology 2011, 17: 212-216. PMID: 21696661, PMCID: PMC3287273, DOI: 10.1177/159101991101700212.
- Fish J, Yan M, Matouk C, St. Bernard R, Ho J, Gavryushova A, Srivastava D, Marsden P. Hypoxic repression of endothelial nitric-oxide synthase transcription is coupled with eviction of promoter histones. Journal Of Biological Chemistry 2010, 285: 11754. PMCID: PMC2857053, DOI: 10.1074/jbc.a109.067868.
- Matouk CC, Marsden PA. Epigenetic Regulation of Vascular Endothelial Gene Expression. Circulation Research 2008, 102: 873-887. PMID: 18436802, DOI: 10.1161/circresaha.107.171025.
- Farhat N, Matouk C, Mamarbachi A, Marsden P, Allen B, Thorin E. Activation of ETB receptors regulates the abundance of ET‐1 mRNA in vascular endothelial cells. British Journal Of Pharmacology 2008, 153: 1420-1431. PMID: 18278064, PMCID: PMC2437912, DOI: 10.1038/bjp.2008.25.
- Matouk C, Marsden P. Chapter 26 Molecular Insights into the Thrombotic Microangiopathies. 2008, 453-cp4. DOI: 10.1016/b978-1-4160-0252-9.50030-6.
- Matouk C, McDonald P, Drake J. Chapter 78 Midbrain Gliomas. 2005, 599-603. DOI: 10.1016/b978-0-7216-8148-1.50081-4.
- Yale Physicians Building800 Howard Avenue, Fl Lower LevelNew Haven, CT 06519
Biography
When he was a medical student, Charles Matouk, MD, met a patient with rapidly progressive dementia and weakness on the right side of his body. He recalls being “astonished” when the patient’s symptoms were fully reversed within a few weeks of having an endovascular procedure in his brain to disconnect an abnormal blood vessel (a vascular malformation) that had been causing the problem. The patient was cured. This experience was so memorable to Dr. Matouk that it inspired his decision to pursue a specialty in neurovascular surgery.
Now the chief of neurovascular surgery at Yale Medicine, Dr. Matouk has expertise in brain aneurysms, vascular malformations of the brain and spinal cord, carotid occlusive disease, acute stroke syndromes and adult-onset hydrocephalus. “In medicine today, a lot of the work that doctors do is either preventative or palliative,” Dr. Matouk remarks. “However, in neurosurgery we are able to use simple, minimally invasive procedures that can actually change everything for a patient. Their disease can be cured.”
As a surgeon, Dr. Matouk focuses on treating each patient as a person. “I hope that what I can provide patients is the opportunity to tell me their story and concerns,” he says. “It’s a partnership. My fundamental role is to help patients make an informed decision that’s right for them.” To help patients understand their conditions and treatment options, Dr. Matouk likes to show them the radiology pictures of their brain, and to sketch out what will happen during the procedure. He often encourages patients to go home and think about the information presented before making a decision to proceed.
In addition to caring for patients, Dr. Matouk is an assistant professor of neurosurgery and of radiology & biomedical imaging. He conducts clinical research on advanced imaging to help determine which aneurysms and vascular malformations are higher risk and should be prioritized for treatment, and which can be watched safely overtime.
Titles
- Associate Professor of Neurosurgery
- Vice Chair of Clinical Affairs, Neurosurgery
- Chief, Neurovascular Surgery
- Director, Neurovascular/Endovascular Fellowship
Education & Training
- FellowshipUniversity of Toronto (2011)
- ResidencyUniversity of Toronto (2009)
- MDUniversity of Calgary (1999)
- BSMcGill University (1996)
Languages Spoken
- English
- Français (French)
Additional Information
- McLaughlin Centre for Molecular Medicine Medical Scientist Training Fellowship: University of Toronto, Canada
- Canadian Institutes of Health Research (CIHR) Research Fellowship: Univeristy of Toronto, Canada
- American Association of Neurological Surgeons (AANS) / Neurosurgery Research & Education Foundation (NREF) Research Fellowship: University of Toronto, Canada
- Royal College of Physicians & Surgeons of CANADA, Neurological Surgery (2009)
- Sujijantarat N, Renedo D, Antonios J, Koo A, Amllay A, Nowicki K, Cord B, Hebert R, de Havenon A, Sheth K, Petersen N, Matouk C. Use of a dedicated open transcarotid access system for neurovascular disease. Journal Of NeuroInterventional Surgery 2024, jnis-2024-021599. PMID: 38719442, DOI: 10.1136/jnis-2024-021599.
- Amllay A, Owolo E, Nowicki K, Sujijantarat N, Koo A, Antonios J, Renedo D, Matouk C, Hebert R. Angiographic evidence of an inadvertent cannulation of the marginal sinus following central line migration: illustrative case. Journal Of Neurosurgery Case Lessons 2024, 7: case23607. PMID: 38684119, PMCID: PMC11058405, DOI: 10.3171/case23607.
- Olexa M, Begunova Y, Dhar R, Matouk C, Sheth K, Gutierrez S, De Havenon A, Petersen N. Quantitative Assessment of Reperfusion Impact on Cerebral Edema and Functional Outcomes in Large-vessel Occlusion Stroke Patients (S23.003). Neurology 2024, 102 DOI: 10.1212/wnl.0000000000205719.
- Olexa M, Begunova Y, Gilmore E, Kim J, Herman A, Beekman R, Magid-Bernstein J, Matouk C, Sheth K, Miller E, Gutierrez S, De Havenon A, Sansing L, Petersen N. Exploring the Relationship Between Cerebrospinal Fluid Interleukin-6 and Cerebral Autoregulation After Subarachnoid Hemorrhage (S23.004). Neurology 2024, 102 DOI: 10.1212/wnl.0000000000205692.
- Hawkes M, Clocchiatti-Tuozzo S, Rivier C, Qureshi A, Matouk C, Petersen N, De Havenon A, Sheth K, Falcone G. Different Response to Blood Pressure Reduction in Lobar and Deep Intracerebral Hemorrhage (P10-2.004). Neurology 2024, 102 DOI: 10.1212/wnl.0000000000206366.
- Jayasundara S, Kim J, Choi R, Rapuano A, Barnes E, Parasram M, Moura M, Uppal P, Chen Y, Top I, Olexa M, Maarek R, Yan J, Beekman R, Magid-Bernstein J, Hebert R, Bahrassa F, Matouk C, Sheth K, Gilmore E, Petersen N. Assessing Effects of Intrathecal Nicardipine on Cerebral Autoregulation and Cortical Activity in Aneurysmal Subarachnoid Hemorrhage (P10-5.019). Neurology 2024, 102 DOI: 10.1212/wnl.0000000000206285.
- Antonios J, Barak T, Gultekin B, Yalcin K, Adenu-Mensah N, Sujijantarat N, Koo A, Haynes J, Hebert R, Matouk C, Gunel M. 306 Endothelial Infiltrating Regulatory B Cells and NK T Cells Precipitate Inflammatory Cascade That Leads to Aneurysmal Rupture. Neurosurgery 2024, 70: 88-89. DOI: 10.1227/neu.0000000000002809_306.
- Sujijantarat N, Antonios J, Koo A, Haynes J, Renedo D, Hebert R, Sheth K, King J, Matouk C. 308 Improvement in Cranial Nerve Neuropathies Following Treatment of Intracranial Aneurysms With Flow Diverters: Institutional Outcomes and Meta-analysis of Literature. Neurosurgery 2024, 70: 89-89. DOI: 10.1227/neu.0000000000002809_308.
- de Havenon A, Zhou L, Koo A, Matouk C, Falcone G, Sharma R, Ney J, Shu L, Yaghi S, Kamel H, Sheth K. Endovascular Treatment of Acute Ischemic Stroke After Cardiac Interventions in the United States. JAMA Neurology 2024, 81: 264-272. PMID: 38285452, PMCID: PMC10825786, DOI: 10.1001/jamaneurol.2023.5416.
- Avery E, Abou-Karam A, Abi-Fadel S, Behland J, Mak A, Haider S, Zeevi T, Sanelli P, Filippi C, Malhotra A, Matouk C, Falcone G, Petersen N, Sansing L, Sheth K, Payabvash S. Radiomics-Based Prediction of Collateral Status from CT Angiography of Patients Following a Large Vessel Occlusion Stroke. Diagnostics 2024, 14: 485. PMID: 38472957, PMCID: PMC10930945, DOI: 10.3390/diagnostics14050485.
- Diogo C, Na D, Sujijantarat N, Matouk C, Callahan B. Diagnostic accuracy of intraoperative neuromonitoring in transcarotid artery revascularization. Journal Of NeuroInterventional Surgery 2024, jnis-2023-021282. PMID: 38378240, DOI: 10.1136/jnis-2023-021282.
- Renedo D, Rivier C, Koo A, Sujijantarat N, Clocchiatti-Tuozzo S, Wu K, Torres-Lopez V, Huo S, Gunel M, de Havenon A, Sheth K, Matouk C, Falcone G. APOE ε4 and Intracerebral Hemorrhage in Patients With Brain Arteriovenous Malformation. JAMA Network Open 2024, 7: e2355368. PMID: 38363572, PMCID: PMC10873768, DOI: 10.1001/jamanetworkopen.2023.55368.
- Hawkes M, Clocchiatti-Tuozzo S, Rivier C, Qureshi A, Matouk C, Petersen N, de Havenon A, Sheth K, Falcone G. Abstract 149: Different Response to Blood Pressure Reduction in Lobar and Deep Intracerebral Hemorrhage. Stroke 2024, 55 DOI: 10.1161/str.55.suppl_1.149.
- Petersen N, Olexa M, Jayasundara S, Falcone G, Gilmore E, Kim J, Matouk C, Alian A, Sheth K, Miller E, Ortega-Gutierrez S, de Havenon A. Abstract 51: Impact of Cerebral Autoregulation on the Relationship Between Blood Pressure Variability and Functional Outcome Following Endovascular Thrombectomy. Stroke 2024, 55 DOI: 10.1161/str.55.suppl_1.51.
- Renedo D, Rivier C, Clocchiatti-Tuozzo S, Huo S, Hebert R, Gunel M, Matouk C, Falcone G, Sheth K. Abstract HUP7: Impact of Social Determinants of Health and Academic Hospital Care on Outcomes After Non-Traumatic Subarachnoid Hemorrhage. Stroke 2024, 55 DOI: 10.1161/str.55.suppl_1.hup7.
- Vanent K, Rivier C, Matouk C, Levitt M, Leslie-Mazwi T, Gill T, Sheth K, Falcone G. Abstract WP159: Chronic Kidney Disease and Risk of Intracerebral Hemorrhage: The Role of Hypertension as a Mediator. Stroke 2024, 55 DOI: 10.1161/str.55.suppl_1.wp159.
- Olexa M, Begunova Y, Yan J, Herman A, Gilmore E, Kim J, Beekman R, Magid-Bernstein J, Matouk C, Sheth K, Miller E, Ortega-Gutierrez S, de Havenon A, Sansing L, Petersen N. Abstract WP152: Association Between Cerebrospinal Fluid Interleukin-6 Levels and Cerebral Autoregulation After Aneurysmal Subarachnoid Hemorrhage. Stroke 2024, 55 DOI: 10.1161/str.55.suppl_1.wp152.
- Olexa M, Begunova Y, Dhar R, Matouk C, Sheth K, Ortega-Gutierrez S, de Havenon A, Petersen N. Abstract 54: Investigating the Relationship Between Reperfusion and Cerebral Edema Using Novel Cerebrospinal Fluid and Net Water Uptake Biomarkers. Stroke 2024, 55 DOI: 10.1161/str.55.suppl_1.54.
- Sorby-Adams A, Guo J, Schleicher R, Mazurek M, Baldassano S, Payavbash S, Sze G, Schindler J, de Havenon A, Goldstein J, Schaefer P, Zabinska J, Lalwani D, Wira C, Matouk C, Lee V, Muir K, Nimjee S, Pinter N, Siddiqui A, Kirsch J, Iglesias J, Rosen M, Sheth K, Kimberly W. Abstract 89: Portable, Low-Field Magnetic Resonance Imaging: Determining Mismatch Following Acute Ischemic Stroke. Stroke 2024, 55 DOI: 10.1161/str.55.suppl_1.89.
- Ghannam M, AlMajali M, Khasiyev F, Dibas M, Qudah A, AlMajali F, Ghazaleh D, Shah A, Fayad F, Joudi K, Zaidat B, Childs C, Levy B, Abouainain Y, Brunschot D, Shu L, Goldstein E, Baig A, Roeder H, Henninger N, de Havenon A, Levy E, Matouk C, Derdeyn C, Leira E, Chaturvedi S, Yaghi S. Transcarotid Arterial Revascularization of Symptomatic Internal Carotid Artery Disease: A Systematic Review and Study-Level Meta-Analysis. Stroke 2024, 55: 921-930. PMID: 38299350, DOI: 10.1161/strokeaha.123.044246.
- Renedo D, Leasure A, Young R, Rivier C, Alhanti B, Grory B, Messe S, Reeves M, Hassan A, Schwamm L, de Havenon A, Matouk C, Sheth K, Falcone G. COVID‐19 Infection Is Associated With Poor Outcomes in Patients With Intracerebral Hemorrhage. Journal Of The American Heart Association 2024, 13: e030999. PMID: 38293940, PMCID: PMC11056169, DOI: 10.1161/jaha.123.030999.
- Prasad A, Gilmore E, Kim J, Begunova L, Olexa M, Beekman R, Falcone G, Matouk C, Ortega-Gutierrez S, Temkin N, Barber J, Diaz-Arrastia R, de Havenon A, Petersen N. Impact of Therapeutic Interventions on Cerebral Autoregulatory Function Following Severe Traumatic Brain Injury: A Secondary Analysis of the BOOST-II Study. Neurocritical Care 2023, 1-9. PMID: 38158481, DOI: 10.1007/s12028-023-01896-x.
- Orscelik A, Matsukawa H, Elawady S, Sowlat M, Cunningham C, Zandpazandi S, Kasem R, Maier I, Jabbour P, Kim J, Wolfe S, Rai A, Starke R, Psychogios M, Shaban A, Goyal N, Yoshimura S, Cuellar H, Howard B, Alawieh A, Romano D, Tanweer O, Mascitelli J, Fragata I, Polifka A, Osbun J, Crosa R, Matouk C, Park M, Levitt M, Brinjikji W, Moss M, Dumont T, Williamson R, Navia P, Kan P, De Leacy R, Chowdhry S, Ezzeldin M, Spiotta A, Kasab S, Collaborators S. Comparative Outcomes of Mechanical Thrombectomy in Acute Ischemic Stroke Patients with ASPECTS 2-3 vs. 4-5. Journal Of Stroke And Cerebrovascular Diseases 2023, 33: 107528. PMID: 38134550, DOI: 10.1016/j.jstrokecerebrovasdis.2023.107528.
- Clouse J, Thaci B, Clark A, Baggett M, Raslan O, Matouk C, Waldau B, Cord B. Successful mechanical thrombectomy for terminal ICA bullet embolism: A case report. Interventional Neuroradiology 2023, 15910199231219021. PMID: 38073079, DOI: 10.1177/15910199231219021.
- Ash M, Dimisko L, Chalhoub R, Howard B, Cawley C, Matouk C, Pabaney A, Spiotta A, Jabbour P, Maier I, Wolfe S, Rai A, Kim J, Psychogios M, Mascitelli J, Starke R, Shaban A, Yoshimura S, De Leacy R, Kan P, Fragata I, Polifka A, Arthur A, Park M, Crosa R, Williamson R, Dumont T, Levitt M, Kasab S, Tjoumakaris S, Liman J, Saad H, Samaniego E, Fargen K, Grossberg J, Alawieh A. Comprehensive analysis of the impact of procedure time and the ‘golden hour’ in subpopulations of stroke thrombectomy patients. Journal Of NeuroInterventional Surgery 2023, jnis-2023-020792. PMID: 37875342, DOI: 10.1136/jnis-2023-020792.
- Mazurek M, Parasuram N, Peng T, Beekman R, Yadlapalli V, Sorby-Adams A, Lalwani D, Zabinska J, Gilmore E, Petersen N, Falcone G, Sujijantarat N, Matouk C, Payabvash S, Sze G, Schiff S, Iglesias J, Rosen M, de Havenon A, Kimberly W, Sheth K. Detection of Intracerebral Hemorrhage Using Low-Field, Portable Magnetic Resonance Imaging in Patients With Stroke. Stroke 2023, 54: 2832-2841. PMID: 37795593, PMCID: PMC11103256, DOI: 10.1161/strokeaha.123.043146.
- Vranic J, Harker P, Stapleton C, Regenhardt R, Dmytriw A, Doron O, Alotaibi N, Leslie-Mazwi T, Gupta R, Berglar I, Tan C, Koch M, Raymond S, Mascitelli J, Patterson T, Seinfeld J, White A, Case D, Roark C, Gandhi C, Al-Mufti F, Cooper J, Matouk C, Sujijantarat N, Devia D, Ocampo-Navia M, Villamizar-Torres D, Puentes J, Patel A. The Impact of Dual Antiplatelet Therapy Duration on Unruptured Aneurysm Occlusion After Flow Diversion: A Multicenter Study. Journal Of Computer Assisted Tomography 2023, 47: 753-758. PMID: 37707405, DOI: 10.1097/rct.0000000000001457.
- Antonios J, Barak T, Gultekin B, Yalcin K, Chamberlain A, Hebert R, Matouk C, Gunel M. O-068 Regulatory B cell and adjunctive immune population drives intracranial aneurysm rupture in patient population. 2023, a53.1-a53. DOI: 10.1136/jnis-2023-snis.68.
- Renedo D, Acosta J, Koo A, Rivier C, Sujijantarat N, de Havenon A, Sharma R, Gill T, Sheth K, Falcone G, Matouk C. Higher Hospital Frailty Risk Score Is Associated With Increased Risk of Stroke: Observational and Genetic Analyses. Stroke 2023, 54: 1538-1547. PMID: 37216451, PMCID: PMC10212531, DOI: 10.1161/strokeaha.122.041891.
- Olexa M, Begunova Y, Bartolome D, Peng T, Matouk C, Sheth K, Petersen N. Investigating the Relationship Between Oximetry Trends During Endovascular Therapy and Neurological Worsening for Patients with Acute Ischemic Stroke (S24.006). Neurology 2023, 100 DOI: 10.1212/wnl.0000000000202997.
- Siddiqui A, Monteiro A, Hanel R, Kan P, Mohanty A, Cortez G, Rabinovich M, Matouk C, Sujijantarat N, Romero C, Stone J, Ebersole K, Fry L, Natarajan S, Thomson B, Ortega-Gutierrez S, Vivanco-Suarez J, Wakhloo A, Levy E. 482 Triple Therapy Versus Dual Antiplatelet Therapy for Dolichoectatic Vertebrobasilar Fusiform Aneurysms Treated With Flow Diverters: The Last Frontier? Neurosurgery 2023, 69: 103-104. DOI: 10.1227/neu.0000000000002375_482.
- Khan A, Khunte M, Wu X, Bajaj S, Payabvash S, Wintermark M, Matouk C, Seidenwurm D, Gandhi D, Parizel P, Mezrich J, Malhotra A. Malpractice Litigation Related to Diagnosis and Treatment of Intracranial Aneurysms. American Journal Of Neuroradiology 2023, 44: 460-466. PMID: 36997286, PMCID: PMC10084911, DOI: 10.3174/ajnr.a7828.
- Hong C, Marianayagam N, Morales-Valero S, Barak T, Tabor J, O’Brien J, Huttner A, Baehring J, Gunel M, Erson-Omay E, Fulbright R, Matouk C, Moliterno J. Vascular steal and associated intratumoral aneurysms in highly vascular brain tumors: illustrative case. Journal Of Neurosurgery Case Lessons 2023, 5: case22512. PMID: 36880509, PMCID: PMC10550659, DOI: 10.3171/case22512.
- Ammar A, Elsamadicy A, Ammar M, Reeves B, Koo A, Falcone G, Hwang D, Petersen N, Kim J, Beekman R, Prust M, Magid-Bernstein J, Acosta J, Herbert R, Sheth K, Matouk C, Gilmore E. Emergent external ventricular drain placement in patients with factor Xa inhibitor-associated intracerebral hemorrhage after reversal with andexanet alfa. Clinical Neurology And Neurosurgery 2023, 226: 107621. PMID: 36791588, DOI: 10.1016/j.clineuro.2023.107621.
- Renedo D, Rivier C, Acosta J, Clocchiatti S, Wu K, Torres-Lopez V, Sheth K, Gunel M, Matouk C, Falcone G. Abstract 51: Apoe Epsilon 4 And Risk Of Bleeding Patients With Brain Arteriovenous Malformations. A Combined Genetic Study In The Uk Biobank And All Of Us. Stroke 2023, 54: a51-a51. DOI: 10.1161/str.54.suppl_1.51.
- Clocchiatti-Tuozzo S, Renedo D, Rivier C, Lopez V, Matouk C, Sheth K, Gill T, Falcone G. Abstract HUP6: Community Deprivation And Healthcare Access/Utilization In Patients With Carotid Stenosis: Results From The All Of Us Research Program. Stroke 2023, 54: ahup6-ahup6. DOI: 10.1161/str.54.suppl_1.hup6.
- Clocchiatti-Tuozzo S, Renedo D, Rivier C, Lopez V, Matouk C, Sheth K, Gill T, Falcone G. Abstract WMP75: Community Deprivation And Healthcare Access/Utilization In Patients With Carotid Stenosis: Results From The All Of UsResearch Program. Stroke 2023, 54: awmp75-awmp75. DOI: 10.1161/str.54.suppl_1.wmp75.
- Renedo D, Leasure A, Acosta J, Young R, Alhanti B, Grory B, Spudich S, Messe S, Reeves M, Hassan A, Schwamm L, Matouk C, Sheth K, Falcone G. Abstract WP130: Intracerebral Hemorrhage Outcomes And Trends During The Covid-19 Pandemic. An Observational Study Of 61,417 Cases. Stroke 2023, 54: awp130-awp130. DOI: 10.1161/str.54.suppl_1.wp130.
- Olexa M, Begunova Y, Bartolome D, Peng T, Sheth K, Matouk C, Petersen N. Abstract 11: Identifiable Patterns Of Noninvasive Cerebral Oximetry During Endovascular Therapy For Acute Ischemic Stroke Are Associated With Neurological Deterioration. Stroke 2023, 54: a11-a11. DOI: 10.1161/str.54.suppl_1.11.
- Parasuram N, Crawford A, Mazurek M, Chavva I, Beekman R, Gilmore E, Petersen N, Payabvash S, Sze G, Eugenio Iglesias J, Omay S, Matouk C, Longbrake E, de Havenon A, Schiff S, Rosen M, Kimberly W, Sheth K. Future of Neurology & Technology: Neuroimaging Made Accessible Using Low-Field, Portable MRI. Neurology 2023, 100: 1067-1071. PMID: 36720639, PMCID: PMC10259275, DOI: 10.1212/wnl.0000000000207074.
- Koo A, Elsamadicy A, Matouk C. In Reply to the Letter to Editor Regarding "Hospital Frailty Risk Score Predicts Adverse Events and Readmission Following Ventriculoperitoneal Shunt Surgery for Normal Pressure Hydrocephalus". World Neurosurgery 2023, 169: 124. PMID: 36585096, DOI: 10.1016/j.wneu.2022.11.023.
- Koo A, Elsamadicy A, Renedo D, Matouk C. Response to letter to the Editor on ‘Utility of the Hospital Frailty Risk Score in patients undergoing endovascular treatment for ruptured aneurysms’. Journal Of NeuroInterventional Surgery 2022, 15: 307-308. PMID: 36319084, DOI: 10.1136/jnis-2022-019708.
- Ackerman-Banks C, Fardelmann K, Lam D, Simmons M, Elder R, Matouk C, Campbell K. Unrepaired Maternal Vein of Galen Malformation in Pregnancy: A Case Report. A&A Practice 2022, 16: e01634. PMID: 36599040, DOI: 10.1213/xaa.0000000000001634.
- Siddiqui A, Monteiro A, Hanel R, Kan P, Mohanty A, Cortez G, Rabinovich M, Matouk C, Sujijantarat N, Ebersole K, Fry L, Natarajan S, Owusu-Adjei B, Ortega-Gutierrez S, Vivanco-Suarez J, Wakhloo A, Levy E. P-017 Triple therapy versus dual antiplatelet therapy for dolichoectatic vertebrobasilar fusiform aneurysms treated with flow-diverters: the last frontier? 2022, a59.1-a59. DOI: 10.1136/neurintsurg-2022-snis.89.
- Bartolome D, Begunova Y, Prasad A, Soto A, Kobsa J, Top I, Quispe-Orozco D, Farooqui M, Zevallos C, Kim J, Gilmore E, Beekman R, De Havenon A, Matouk C, Sheth K, Ortega-Gutiérrez S, Petersen N. Cerebral hypoperfusion after nimodipine administration is associated with worse functional outcomes in subarachnoid hemorrhage patients (P6-7.001). Neurology 2022, 98 DOI: 10.1212/wnl.98.18_supplement.3609.
- Begunova Y, Bartolome D, Kobsa J, Soto A, Prasad A, Galecio M, Vivanco-Suarez J, Quispe-Orozco D, Farooqui M, Sansing L, Schindler J, De Havenon A, Matouk C, Sheth K, Ortega-Gutierrez S, Petersen N. Poor Collaterals and Rapid Early Infarct Progression Are Associated With Increased Vulnerability to Blood Pressure Reductions (S21.002). Neurology 2022, 98 DOI: 10.1212/wnl.98.18_supplement.3104.
- Prasad A, Kobsa J, Soto A, Bartolome D, Begunova L, Kim J, Gilmore E, Sheth K, Matouk C, De Havenon A, Diaz-Arrastia R, Petersen N. Cerebral Autoregulatory Function Before, During, and After Therapeutic Interventions Following Severe Traumatic Brain Injury: A Secondary Analysis of the BOOST-II Study (S21.001). Neurology 2022, 98 DOI: 10.1212/wnl.98.18_supplement.557.
- Top I, Chen Y, Bartolome D, Rapuano A, Gilmore E, Sheth K, Matouk C, Petersen N, Kim J. Impaired Cerebral Autoregulation Related Blood Pressure Reductions After Nimodipine Are Associated with Ischemic Changes on EEG After Subarachnoid Hemorrhage (P13-10.002). Neurology 2022, 98 DOI: 10.1212/wnl.98.18_supplement.3539.
- Koo A, Elsamadicy A, Sarkozy M, Sherman J, Reeves B, Freedman I, Antonios J, Sujijantarat N, Renado D, Hebert R, Malhotra A, Matouk C. 307 The Hospital Frailty Risk Score Independently Predicts Increased Complication Rates and Healthcare Resource Utilization After Endovascular Treatment of Ruptured Aneurysms. Neurosurgery 2022, 68: 67-68. DOI: 10.1227/neu.0000000000001880_307.
- Bartolome D, Begunova Y, Prasad A, Soto A, Kobsa J, Top I, Quispe-Orozco D, Farooqui M, Zevallos C, Kim J, Gilmore E, Beekman R, de Havenon A, Matouk C, Sheth K, Ortega-Gutierrez S, Petersen N. Abstract 89: Nimodipine-induced Blood Pressure Reductions Below Personalized Limits Of Autoregulation Are Associated With Worse Outcomes After Subarachnoid Hemorrhage. Stroke 2022, 53: a89-a89. DOI: 10.1161/str.53.suppl_1.89.
- Vanent K, Acosta J, Both C, Leasure A, Noche R, Levitt M, Matouk C, Gunel M, Sheth K, Falcone G. Abstract 105: Polygenic Burden Of Hypertension-related Alleles Leads To Non-traumatic Subarachnoid Hemorrhage At Younger Ages. Stroke 2022, 53: a105-a105. DOI: 10.1161/str.53.suppl_1.105.
- Renedo D, Acosta J, Sheth K, Matouk C, Falcone G. Abstract 123: Carotid Artery Stenosis In Underrepresented Populations Defined By Factors Other Than Race/ethnicity: Results From All Of Us. Stroke 2022, 53: a123-a123. DOI: 10.1161/str.53.suppl_1.123.
- Atillasoy J, Leasure A, Schwartz A, Reznik M, Moody S, Bevers M, Matouk C, Falcone G, Sansing L, Kimberly W, Sheth K. Abstract TP134: Association Of Neutrophil-lymphocyte Ratio With Functional Outcome In Spontaneous Intracerebral Hemorrhage. Stroke 2022, 53: atp134-atp134. DOI: 10.1161/str.53.suppl_1.tp134.
- Choi J, Saver J, Nogueira R, Poli S, Nguyen T, Chen M, Matouk C, Pile-Spellman J. Hybernia post-mechanical thrombectomy – Endovascular cerebral hypothermia trial in acute ischemic stroke (post-mtech trial). Journal Of The Neurological Sciences 2021, 429: 119718. DOI: 10.1016/j.jns.2021.119718.
- Wu X, Wira C, Matouk C, Forman H, Gandhi D, Sanelli P, Schindler J, Malhotra A. Drip-and-ship versus mothership for endovascular treatment of acute stroke: A comparative effectiveness analysis. International Journal Of Stroke 2021, 17: 315-322. PMID: 33759645, DOI: 10.1177/17474930211008701.
- Acosta J, Szejko N, Lopez V, Both C, Sansing L, Sheth K, Matouk C, Falcone G. Klotho-VS Heterozygosity is Associated with Lower Risk of Non-traumatic Subarachnoid Hemorrhage (2737). Neurology 2021, 96 DOI: 10.1212/wnl.96.15_supplement.2737.
- Peshwe K, Nguyen C, Kodali S, Kobsa J, Prasad A, Soto A, Wira C, Matouk C, Sheth K, Petersen N. Abstract MP36: Blood Pressure Reductions in the Hyperacute Phase of Large Vessel Occlusion Ischemic Stroke Are Associated With Infarct Progression and Poor Functional Outcome. Stroke 2021, 52 DOI: 10.1161/str.52.suppl_1.mp36.
- Koo A, Elsamadicy A, Lin I, David W, Reeves B, Santarosa C, Cord B, Malhotra A, Kahle K, Matouk C. Patient Risk Factors Associated with 30- and 90- Day Readmission after Ventriculoperitoneal Shunt Placement for Idiopathic Normal Pressure Hydrocephalus in Elderly Patients. Neurosurgery 2020, 67 DOI: 10.1093/neuros/nyaa447_202.
- Koo A, Elsamadicy A, Lin I, David W, Freedman I, Sujijantarat N, Cord B, Hebert R, Bahrassa F, Malhotra A, Matouk C. Predictors of Extended Length of Stay following Treatment of Unruptured Adult Cerebral Aneurysms. Neurosurgery 2020, 67 DOI: 10.1093/neuros/nyaa447_147.
- Robert S, Matouk C. Stem Cell Therapy for Stroke. 2020, 331-345. DOI: 10.1007/978-3-030-56954-9_15.
- Matouk C, Cord B. Vascular Malformations of the Brain and Spine. 2020, 177-191. DOI: 10.1007/978-3-030-52552-1_14.
- Nguyen C, Silverman A, Wang A, Kodali S, Strander S, Kimmel A, Peshwe K, de Havenon A, Gilmore E, Sansing L, Schindler J, Matouk C, Sheth K, Petersen N. Risk of Worse Outcome in Stroke Patients with High Blood Pressure Variability After Endovascular Thrombectomy May Be Amplified by Impaired Cerebral Autoregulation (4457). Neurology 2020, 94 DOI: 10.1212/wnl.94.15_supplement.4457.
- Cahn B, Shah J, Dyvorne H, O’Halloran R, Poole M, Yuen M, Mazurek M, Ward A, Payabvash S, Beekman R, Brown S, Falcone G, Gobeske K, Petersen N, Jasne A, Sharma R, Schindler J, Sansing L, Gilmore E, Wira C, Matouk C, Sze G, Rosen M, Kimberly W, Sheth K. Deployment of Portable, Bedside, Low-field Magnetic Resonance Imaging for Evaluation of Stroke Patients (272). Neurology 2020, 94 DOI: 10.1212/wnl.94.15_supplement.272.
- Kuohn L, Leasure A, Acosta J, Vanent K, Murthy S, Kamel H, Matouk C, Sansing L, Falcone G, Sheth K. Causes of Death in a Longitudinal Analysis of Spontaneous Intracerebral Hemorrhage Survivors (4228). Neurology 2020, 94 DOI: 10.1212/wnl.94.15_supplement.4228.
- Acosta J, Both C, Brown S, Leasure A, Vanent K, Noche R, Kirsch E, Petersen N, Matouk C, Gunel M, Gill T, Sheth K, Falcone G. Abstract 66: Causal Associations Between Genetically-determined Smoking and Risk of Subarachnoid Hemorrhage. Stroke 2020, 51 DOI: 10.1161/str.51.suppl_1.66.
- Silverman A, Wang A, Kodali S, Strander S, Kimmel A, Nguyen C, Peshwe K, Matouk C, Kimberly W, Sheth K, Tan C, Petersen N. Abstract TP417: An Autoregulation-Derived Prediction Model for Midline Shift After Ischemic Stroke. Stroke 2020, 51 DOI: 10.1161/str.51.suppl_1.tp417.
- Silverman A, Kodali S, Strander S, Gilmore E, Kimmel A, Wang A, Cord B, Falcone G, Hebert R, Matouk C, Sheth K, Petersen N. Deviation from Dynamic and Personalized Optimal Blood Pressure Targets is Associated With Worse Functional Outcomes After Aneurysmal Subarachnoid Hemorrhage. Neurosurgery 2019, 66: 310-186. DOI: 10.1093/neuros/nyz310_186.
- Cord B, Wang A, Chouairi F, Koo A, Porto C, Silverman A, Kodali S, Strander S, Falcone G, Sheth K, Hebert R, Sansing L, Schindler J, Petersen N, Matouk C. Percutaneous Trans-Carotid Puncture for Mechanical Thrombectomy in Acute Ischemic Stroke Patients is Safe and Effective: A Large, Single-Center Case Series. Neurosurgery 2019, 66: 310-167. DOI: 10.1093/neuros/nyz310_167.
- Cord B, Santarosa C, Sujijantarat N, Kundishora A, Falcone G, Sheth K, Sansing L, Schindler J, Petersen N, Matouk C. Preliminary Experience With Proximal Flow Reversal During Intracranial Balloon Angioplasty and Stenting for Symptomatic, Severe Intracranial Stenosis. Neurosurgery 2019, 66: 310-675. DOI: 10.1093/neuros/nyz310_675.
- Wu X, Gandhi D, Matouk C, Schindler J, Hughes D, Forman H, Sanelli P, Malhotra A. Implications of Achieving TICI 2b Versus TICI 3 Reperfusion in Patients With Ischemic Stroke: A Cost-Effectiveness Analysis. Neurosurgery 2019, 66: 310-670. DOI: 10.1093/neuros/nyz310_670.
- Silverman A, Wang A, Kodali S, Strander S, Cord B, Hebert R, Matouk C, Gilmore E, Sheth K, Petersen N. Abstract 147: Individualized Blood Pressure Management After Subarachnoid Hemorrhage Using Real-time Autoregulation Monitoring: A Pilot Study Using NIRS and ICP-derived Limits of Autoregulation. Stroke 2019, 50 DOI: 10.1161/str.50.suppl_1.147.
- Littauer R, Sather J, Rothenberg C, Finn E, Yip M, Matouk C, Pham L, Sheth K, Ulrich A, Parwani Y, Venkatesh A. 57 Improving the Safety and Quality of Inter-Hospital Transfer for Nontraumatic Intracerebral and Subarachnoid Hemorrhage. Annals Of Emergency Medicine 2018, 72: s25-s26. DOI: 10.1016/j.annemergmed.2018.08.062.
- Mandell D, Mossa-Basha M, Qiao Y, Hess C, Hui F, Matouk C, Johnson M, Daemen M, Vossough A, Edjlali M, Saloner D, Ansari S, Wasserman B, Mikulis D. Intracranial vessel wall MRI: Principles and expert consensus Recommendations of the American Society of Neuroradiology. International Journal Of Cerebrovascular Diseases 2018, 26: 641-653. DOI: 10.3760/cma.j.issn.1673-4165.2018.09.001.
- Wu X, Matouk C, Malhotra A. 316 Screening for Intracranial Aneurysms in Patients With Autosomal Dominant Polycystic Kidney Disease. Neurosurgery 2018, 65: 128. DOI: 10.1093/neuros/nyy303.316.
- Wu X, Cord B, Sommaruga S, Matouk C, Malhotra A. 315 Comparative Effectiveness Analysis of Pipeline Embolization Device versus Coiling in Unruptured Aneurysms Less Than 10 mm in Size. Neurosurgery 2018, 65: 127-128. DOI: 10.1093/neuros/nyy303.315.
- Wu X, Cord B, Sommaruga S, Matouk C, Malhotra A. 148 Management of Unruptured Intracranial Aneurysms in the Elderly. Neurosurgery 2018, 65: 97. DOI: 10.1093/neuros/nyy303.148.
- Mampre D, Wang A, Sheth K, Tan C, Hebert R, Matouk C, Petersen N. 105 Decreases in Blood Pressure During Endovascular Stroke Therapy Are Common and Associated With Poor Functional Outcome. Neurosurgery 2018, 65: 82. DOI: 10.1093/neuros/nyy303.105.
- Adeeb N, Griessenauer C, Dmytriw A, Shallwani H, Gupta R, Foreman P, Shakir H, Moore J, Limbucci N, Mangiafico S, Kumar A, Michelozzi C, Zhang Y, Pereira V, Matouk C, Harrigan M, Siddiqui A, Levy E, Renieri L, Marotta T, Cognard C, Ogilvy C, Thomas A. Risk of Branch Occlusion and Ischemic Complications with the Pipeline Embolization Device in the Treatment of Posterior Circulation Aneurysms. American Journal Of Neuroradiology 2018, 39: 1303-1309. PMID: 29880475, PMCID: PMC7655425, DOI: 10.3174/ajnr.a5696.
- Sommaruga S, Cord B, Santarosa C, Yeung J, Johnson M, Hebert R, Bijlenga P, Schaller K, Matouk C. High-Resolution Vessel Wall MRI in Ruptured Cranial Dural Arteriovenous Fistulas. Journal Of Neurological Surgery Part A Central European Neurosurgery 2018, 79: s1-s27. DOI: 10.1055/s-0038-1660759.
- Sommaruga S, Chu S, Hwang D, Dearborn J, Sansing L, Cord B, Santarosa C, Samarth G, Petersen N, Gilmore E, Schindler J, Bijlenga P, Schaller K, Matouk C, Sheth K, Falcone G. History of Intracranial Hemorrhage Is Associated with In-Hospital Mortality in Ischemic Stroke Patients Treated with Intravenous Thrombolytics. Journal Of Neurological Surgery Part A Central European Neurosurgery 2018, 79: s1-s27. DOI: 10.1055/s-0038-1660745.
- Sommaruga S, Beekman R, Chu S, King Z, Matouk C, Hwang D, Sheth K, Falcone G. Spontaneous Intracerebral Hemorrhage in the Elderly Population. Journal Of Neurological Surgery Part A Central European Neurosurgery 2018, 79: s1-s27. DOI: 10.1055/s-0038-1660768.
- Sommaruga S, Cord B, Santarosa C, Malhotra A, Jonhson M, Sheth K, Gunel M, Herbert R, Bijlenga P, Schaller K, Falcone G, Matouk C. Predictors of Vessel Wall Enhancement in Unruptured Intracranial Aneurysms. Journal Of Neurological Surgery Part A Central European Neurosurgery 2018, 79: s1-s27. DOI: 10.1055/s-0038-1660769.
- Sommaruga S, Cord B, Minja F, Malhotra A, Johnson M, Bijlenga P, Schaller K, Matouk C. High-Resolution MRI with Black Blood Sequence Increases Physician Confidence in Identification of Rupture Site in Cerebral AVMs: Application to Treatment Strategies. Journal Of Neurological Surgery Part A Central European Neurosurgery 2018, 79: s1-s27. DOI: 10.1055/s-0038-1660760.
- Sommaruga S, Cord B, Molhotra A, Johnson M, Minja F, Gunel M, Sheth K, Herbert R, Melnikov F, Schaller K, Mandell D, Bijlenga P, Falcone G, Matouk C. Abstract WMP31: Vessel Wall Enhancement is Associated With Clinical and Imaging Markers of Aneurysm Instability. Stroke 2018, 49 DOI: 10.1161/str.49.suppl_1.wmp31.
- Wang A, Mampre D, Sheth K, Tan C, Matouk C, Hebert R, Petersen N. Abstract WP320: Blood Pressure Reduction During Endovascular Stroke Therapy is Associated With Poor Functional Outcome. Stroke 2018, 49 DOI: 10.1161/str.49.suppl_1.wp320.
- Saba L, Yuan C, Hatsukami T, Balu N, Qiao Y, DeMarco J, Saam T, Moody A, Li D, Matouk C, Johnson M, Jäger H, Mossa-Basha M, Kooi M, Fan Z, Saloner D, Wintermark M, Mikulis D, Wasserman B. Carotid Artery Wall Imaging: Perspective and Guidelines from the ASNR Vessel Wall Imaging Study Group and Expert Consensus Recommendations of the American Society of Neuroradiology. American Journal Of Neuroradiology 2018, 39: e9-e31. PMID: 29326139, PMCID: PMC7410574, DOI: 10.3174/ajnr.a5488.
- Yip M, Sather J, Sheth K, Matouk C, Littauer R, Finn E, Rothenberg C, Costello D, Parwani V, Venkatesh A. 295 Interhospital Transfer is Not a Predictor of In-Hospital Mortality for Patients With Nontraumatic Intracranial Hemorrhage. Annals Of Emergency Medicine 2017, 70: s116-s117. DOI: 10.1016/j.annemergmed.2017.07.273.
- Cord B, Sommaruga S, Hebert R, Malhotra A, Johnson M, Minja F, Gunel M, Sheth K, Falcone G, Matouk C. 168 Wall Enhancement in Unruptured Aneurysms is Associated with Symptomatic Presentation and Size. Neurosurgery 2017, 64: 243. DOI: 10.1093/neuros/nyx417.168.
- White J, Matouk C. Aneurysmal Subarachnoid Hemorrhage. 2017, 55-74. DOI: 10.1007/978-3-319-48669-7_4.
- O-021 Pipeline embolization of posterior circulation aneurysms: a multicenter study of 131 aneurysmsGriessenauer C, Ogilvy C, Adeeb N, Dmytriw A, Foreman P, Shallwani H, Limbucci N, Mangiafico S, Kumar A, Michelozzi C, Krings T, Pereira V, Matouk C, Harrigan M, Shakir H, Siddiqui A, Levy E, Renieri L, Marotta T, Cognard C, Thomas A. O-021 Pipeline embolization of posterior circulation aneurysms: a multicenter study of 131 aneurysms. Journal Of NeuroInterventional Surgery 2017, 9: a13. DOI: 10.1136/neurintsurg-2017-snis.21.
- Dmytriw, Adeeb N, Kumar A, Griessenauer C, Ogilvy C, Foreman P, Shallwani H, Limbucci N, Mangiafico S, Michelozzi C, Krings T, Pereira V, Matouk C, Zhang Y, Harrigan M, Phan K, Shakir H, Siqqiqui A, Levy E, Renieri L, Cognard C, Thomas A, Marotta T. O-018 Flow diversion for the treatment of basilar apex aneurysms. Journal Of NeuroInterventional Surgery 2017, 9: a11. DOI: 10.1136/neurintsurg-2017-snis.18.
- Cord B, Sommaruga S, Yeung J, Johnson M, Matouk C. E-050 First-Line Treatment by Embolization with Intention-to-Cure in the Management of Cranial Dural Arteriovenous Fistulas. Journal Of NeuroInterventional Surgery 2016, 8: a70. DOI: 10.1136/neurintsurg-2016-012589.122.
- Malhotra A, Wu X, Kalra V, Matouk C, Forman H. Regarding “Clinical and Imaging Follow-Up of Patients with Coiled Basilar Tip Aneurysms Up to 20 Years”. American Journal Of Neuroradiology 2016, 37: e39-e39. PMID: 26822726, PMCID: PMC7960187, DOI: 10.3174/ajnr.a4708.
- Coutinho J, Sacho R, Schaafsma J, Agid R, Krings T, Radovanovic I, Matouk C, Mikulis D, Mandell D. High-Resolution Vessel Wall Magnetic Resonance Imaging in Angiogram-Negative Non-Perimesencephalic Subarachnoid Hemorrhage. Clinical Neuroradiology 2015, 27: 175-183. PMID: 26608742, DOI: 10.1007/s00062-015-0484-x.
- Bulsara K, Grant R, Matouk C. Practical Microsurgical and Endovascular Treatment of Vasospasm. 2015, 75-75. DOI: 10.5005/jp/books/12423_12.
- Matouk CC, Mandell DM, Günel M, Bulsara KR, Malhotra A, Hebert R, Johnson MH, Mikulis DJ, Minja FJ. Vessel Wall Magnetic Resonance Imaging Identifies the Site of Rupture in Patients With Multiple Intracranial AneurysmsProof of Principle. Neurosurgery 2013, 72: 492-496. PMID: 23151622, DOI: 10.1227/neu.0b013e31827d1012.
- Marsden P, Matouk C, Turgeon P. Epigenetics and stroke risk – beyond the static DNA code. Advances In Genomics And Genetics 2012, Volume 2: 67-84. DOI: 10.2147/agg.s18697.
- Matouk CC, Kaderali Z, terBrugge KG, Willinsky RA. Long-Term Clinical and Imaging Follow-Up of Complex Intracranial Aneurysms Treated by Endovascular Parent Vessel Occlusion. American Journal Of Neuroradiology 2012, 33: 1991-1997. PMID: 22555575, PMCID: PMC7964607, DOI: 10.3174/ajnr.a3079.
- Alkins R, Matouk CC, Cruz JP, Marotta T, Montanera W, Spears J. Carotid Artery Angioplasty and Stenting for Patients Less than 70 Years-of-Age. Canadian Journal Of Neurological Sciences / Journal Canadien Des Sciences Neurologiques 2012, 39: 338-342. PMID: 22547514, DOI: 10.1017/s0317167100013470.
- Martin AR, Cruz JP, Matouk CC, Spears J, Marotta TR. The Pipeline Flow-Diverting Stent for Exclusion of Ruptured Intracranial Aneurysms With Difficult Morphologies. Neurosurgery 2012, 70: ons21-ons28. PMID: 21841519, DOI: 10.1227/neu.0b013e3182315ee3.
- Mandell DM, Matouk CC, Farb RI, Krings T, Agid R, terBrugge K, Willinsky RA, Swartz RH, Silver FL, Mikulis DJ. Vessel Wall MRI to Differentiate Between Reversible Cerebral Vasoconstriction Syndrome and Central Nervous System Vasculitis. Stroke 2011, 43: 860-862. PMID: 22156692, DOI: 10.1161/strokeaha.111.626184.
- Matouk C, Hanbidge A, Mandell D, Terbrugge K, Agid R. Osteogenesis Imperfecta, Multiple Intra-Abdominal Arterial Dissections and a Ruptured Dissecting-Type Intracranial Aneurysm. Interventional Neuroradiology 2011, 17: 371-375. PMID: 22005702, PMCID: PMC3396044, DOI: 10.1177/159101991101700315.
- Ebinu J, Matouk C, Wallace M, Terbrugge K, Krings T. Hydrocephalus Secondary to Hydrodynamic Disequilibrium in an Adult Patient with a Choroidal-Type Arteriovenous Malformation. Interventional Neuroradiology 2011, 17: 212-216. PMID: 21696661, PMCID: PMC3287273, DOI: 10.1177/159101991101700212.
- Fish J, Yan M, Matouk C, St. Bernard R, Ho J, Gavryushova A, Srivastava D, Marsden P. Hypoxic repression of endothelial nitric-oxide synthase transcription is coupled with eviction of promoter histones. Journal Of Biological Chemistry 2010, 285: 11754. PMCID: PMC2857053, DOI: 10.1074/jbc.a109.067868.
- Matouk CC, Marsden PA. Epigenetic Regulation of Vascular Endothelial Gene Expression. Circulation Research 2008, 102: 873-887. PMID: 18436802, DOI: 10.1161/circresaha.107.171025.
- Farhat N, Matouk C, Mamarbachi A, Marsden P, Allen B, Thorin E. Activation of ETB receptors regulates the abundance of ET‐1 mRNA in vascular endothelial cells. British Journal Of Pharmacology 2008, 153: 1420-1431. PMID: 18278064, PMCID: PMC2437912, DOI: 10.1038/bjp.2008.25.
- Matouk C, Marsden P. Chapter 26 Molecular Insights into the Thrombotic Microangiopathies. 2008, 453-cp4. DOI: 10.1016/b978-1-4160-0252-9.50030-6.
- Matouk C, McDonald P, Drake J. Chapter 78 Midbrain Gliomas. 2005, 599-603. DOI: 10.1016/b978-0-7216-8148-1.50081-4.
- Yale Physicians Building800 Howard Avenue, Fl Lower LevelNew Haven, CT 06519
- Yale Physicians Building800 Howard Avenue, Fl Lower LevelNew Haven, CT 06519