Departments

We provide expert evaluation and treatment to adult and pediatric patients across the entire spectrum of allergic and immunologic disorders. Our board-certified specialists have specific clinical and scientific expertise, and are highly capable of providing comprehensive, thoughtful care from the most common to the rarest conditions. Our physicians meet weekly to discuss the management of complicated cases. Yale has been the site of several key research breakthroughs in the field, including the discovery of new inherited immunological diseases and the development of a crucial understanding of the underlying causes of allergies. We offer comprehensive evaluation of both common and rare allergy and immunology conditions, including allergy skin and blood testing, oral food challenges, drug allergy testing, and contact dermatitis patch testing. We offer allergic rhinitis and asthma care through recommendations for environmental controls and pharmacological controller therapy, and biologic therapies for severe asthma, chronic rhinosinusitis with nasal polyposis, as well as chronic urticaria and hereditary angioedema. We have expertise in management of immune deficiencies with intravenous and subcutaneous immunoglobulin replenishment. We also provide consultations for drug allergy desensitization when needed. Among the conditions we treat are: Allergic rhinoconjunctivitis (nasal and eye allergies) Asthma Chronic rhinosinusitis Food allergy Insect sting allergy Medication allergy Urticaria (hives) Angioedema Hereditary angioedema Atopic Dermatitis Contact Dermatitis Common variable immunodeficiency Secondary immune deficiencies Our service has specific strength in the management of inherited immune deficiencies, with a dedicated service that closely collaborates with experts across other specialties. Through a long-standing collaboration with Yale Laboratory Medicine, patients have access to a broad array of state-of-the-art immunological testing. Our care for children and adolescents includes treatment for: Asthma Our doctors collaborate with colleagues in the Pediatric Asthma Program to ensure that our patients receive comprehensive asthma care, including: Evaluation, diagnosis, and management of childhood asthma for patients with varying degrees of severity Testing for allergic precipitants Mechanical analysis of respiratory function Outreach care at patients' homes when needed Allergy Testing for allergens, desensitization, and immunotherapy Allergic rhinoconjunctivitis Drug allergy Food allergy Insect venom allergy Urticaria (hives), mastocytosis, anaphylaxis Hereditary angioedema Primary Immunodeficiency and Recurrent Infections Testing for antibody deficiency, cellular immunodeficiency, and complement disorders Treatment of primary immunodeficiency diseases, including intravenous immunoglobulin therapy Evaluation and management of recurrent infections, including fungal infections

We offer state-of-the-art evaluation and treatment for patients with a wide range of lung disorders, including asthma, chronic obstructive pulmonary disease (COPD), emphysema, lung cancer, and undiagnosed or general respiratory problems. Many patients come to us with work-related pulmonary disease or with sleep disorders. They might not have a diagnosis, but have symptoms such as persistent or nagging cough, or shortness of breath at rest or with exertion. Our skilled, experienced specialists can diagnose and take care of difficult or unusual problems. The history of our center dates back more than a century, when it was set up through a bequest from Sarah Winchester in memory of her husband, William Wirt Winchester, and their young daughter, both of whom succumbed to tuberculosis. This gift resulted in the establishment of the original Winchester Hospital in West Haven, dedicated to the care of patients with tuberculosis. Today, the Winchester Center for Lung Disease at Yale New Haven Hospital is committed to the integration of cutting-edge patient care, education, and research across the full spectrum of pulmonary disorders. Our specialists are faculty members of the Yale School of Medicine Section of Pulmonary, Critical Care and Sleep Medicine, with national and international expertise in treating even the most challenging lung conditions. The center is continually evolving to meet changing needs. Most recently, in response to COVID-19, the center developed a Post-COVID-19 Recovery Program , which offers pulmonary-focused, multidisciplinary evaluation and care for patients recovering from COVID-19. In addition to our comprehensive general pulmonary practice, we offer the specialty center programs listed below. For more information about any of these programs, call the Winchester Center for Lung Disease at 203-495-2410. Adult Cystic Fibrosis Center Cystic fibrosis (CF) was previously thought of as a childhood disease, but is now considered a chronic disease because more adults in the U.S. are living longer with CF and maintaining good quality of life. The Adult CF Program provides team-based care for adults with CF on both an inpatient and outpatient basis. Our comprehensive program includes diagnosis, treatment, and counseling for sinus, pulmonary, gastrointestinal, liver, nutritional, endocrine, mental health, and reproductive issues. Chronic Obstructive Pulmonary Disease (COPD) Chronic obstructive pulmonary disease (COPD) is an inflammatory lung disease that blocks airflow from the lungs and makes it difficult to breathe. The COPD Program (including emphysema, chronic bronchitis, and asthma/COPD overlap syndrome) provides a personalized treatment plan for each patient to help manage their COPD. Whether patients have mild symptoms, need rehabilitation, or require assisted ventilation, we can help. Chronic Pulmonary Infection Research and Treatment (CPIRT) This program is focused on the leading innovative care and research for acute

Our program, focused on adult primary care, is known for its excellence and emphasis on prevention and wellness. We efficiently manage potential medical problems as they arise, and collaborate with specialists when needed. Our practice includes internal medicine physicians, advanced nurse practitioners, a clinical psychologist, a social worker, registered-nurse patient care coordinators, licensed practical nurses, medical assistants, clerical office staff, and a practice supervisor. Our goal is to provide patients with the highest quality, personalized healthcare in the Patient-Centered Medical Home (PCMH) model of care. The PCMH model of care focuses on five areas: Building strong, collaborative health care teams that work together to meet the needs of patients Providing patient-centered care addressing the whole person, respecting patients’ values and preferences Coordinating comprehensive health care through clear communication among patients, families, caregivers, medical and behavioral health providers, hospitals, and other facilities Improving patients’ access to care, through such initiatives as expanded office hours and providing email access to electronic medical records Improving health care quality and standards by providing evidence-based care, patient and family education, and self-management support We would like to hear your direct feedback regarding your experience as a patient/family member of our clinic. Please visit the YIMA Patient/Family Comment Box to provide your feedback. Sign up for MyChart , our secure online patient portal, that gives you access to all of your Yale health information whenever you need it, wherever you may be.

At the Yale Pediatric Infectious Diseases Consultation Program, our internationally recognized team of clinicians focuses on treating a wide array of viral, bacterial, and parasitic infections. Through our outpatient clinical services, we diagnose and treat infectious diseases in children. In addition to HIV/AIDS, tuberculosis, and Lyme disease, our doctors are experts in: Acquired and congenital infections in newborns Infections in immunocompromised patients Fungal infections Respiratory tract infections Tropical medicine and parasitology Transplant ID Outpatient consultations in Infectious Diseases are provided at The Children's Hospital at Yale New Haven, the major teaching hospital of the Yale School of Medicine. Appointments require a referral from a Primary care provider. To schedule a consultation, physicians should call the YM CARE Center at 1-877-925-3637 (1-877-YALE MDS).

Our internationally recognized team of clinicians focuses on treating a wide array of viral, bacterial, and parasitic infections. Through our outpatient clinical services, we diagnose and treat infectious diseases in children from throughout New England and the Mid-Atlantic states. In addition to HIV/AIDS, tuberculosis, and Lyme disease, our doctors are experts in: Acquired and congenital infections in newborns Infections in immunocompromised patients Fungal infections Respiratory tract infections Tropical medicine and parasitology

The physicians in our General Internal Medicine section are national leaders in their fields, and provide dedicated, comprehensive patient care in both inpatient and outpatient settings at several sites across Connecticut: At Yale Internal Medicine Associates in New Haven, we provide state-of-the-art general medical care for adults. At the New Haven Primary Care Consortium (NHPCC), located at 150 Sargent Drive in New Haven, CT, we provide comprehensive primary care, as well as specialized programs in traveling health, rheumatology, dermatology, podiatry, mental health, and addiction medicine. The Occupational and Environmental Medicine clinic focuses on the diagnosis, treatment, and prevention of diseases due to chemical, biological, and physical hazards in the workplace and environment. The Primary Care Center located at the VA Connecticut Healthcare System in West Haven is also a major clinical and teaching site, and provides specialized Women’s Health and stroke care. The Medicine-Pediatric Clinic is located at St. Mary’s Hospital, 133 Scovill Street, in Waterbury. The Yale Addiction Medicine Consult Services provide hospital-based addiction assessment and treatment to patients who are hospitalized at Yale New Haven Hospital. Specialized programs in dermatology, mental health, rheumatology, and health care for travelers Medical forensic exams for individuals with claims of torture who are seeking asylum in the U.S. Specialized program for the treatment of substance use disorders We are also involved in community outreach and service programs that expand the reach of our research and clinical programs. Our research programs in such areas as substance abuse, occupational medicine, and chronic disease management provide our patients in the community with a variety of opportunities to access care and improve their health. Many of our faculty members are graduates of the Robert Wood Johnson Clinical Scholars Program.

Yale Infectious Diseases cares for ambulatory and hospitalized patients with every variety of infectious disease. Specialized services are offered in such areas as traveler’s health, tick-borne diseases, HIV, and related disorders. Research explores such areas as Lyme disease, West Nile and Zika virus, microbial pathogenesis, pneumonia and UTI in older adults, HIV, meningitis, malaria and international health, and nosocomial infections. We are both consultants, working hand-in-hand with referring physicians or groups, and principal caregivers for our patients. Our care is multidisciplinary, involving skilled nurses, dietitians, social workers, and other physicians to deliver the best care possible. Specialized care is offered in the following areas: Hospital-acquired infection control and management Central nervous system infections Fungal infections Hospital epidemiology Traveler's medicine/international health HIV/AIDS Care Lyme disease and tick-borne illnesses Expertise in treating infections in solid organ and stem cell transplants Comprehensive AIDS care and prevention services for people living with and at risk for HIV Multiple observational studies and clinical trial expertise in the study of HIV, HCV, immunology of aging, pneumonia, pseudomonas, tuberculosis (including MDR), urinary tract infections, and tick- and mosquito-borne diseases

At the Yale Chronic Obstructive Pulmonary Disease (COPD) program, our highly trained and skilled specialists provide comprehensive and multidisciplinary treatment to patients with COPD, an inflammatory lung disease that obstructs airflow from the lungs, making it increasingly difficult to breathe. We care for individuals: With emphysema With chronic bronchitis With COPD with associated bronchiectasis With asthma/COPD overlap With COPD/obstructive sleep apnea overlap With combined emphysema and pulmonary fibrosis (in conjunction with our interstitial lung disease team) Who experience frequent disease exacerbations and/or hospitalizations Under consideration for surgical therapies for emphysema (such as bullectomy, lung volume reduction surgery, and lung transplantation) Who need a pre-operative respiratory assessment for other forms of surgery With a suspected genetic basis for their disease (such as alpha-1-antitrypsin deficiency) With chronic respiratory failure related to COPD Patients suffering from COPD may experience flare-ups that require hospitalization, leaving them feeling weaker. Our physicians tailor treatment plans to help them manage their COPD so that they can live life to the fullest. Our physicians are also exploring therapies and medications that can help patients in the future. Whether patients have mild symptoms, need rehabilitation, or assisted ventilation, we can help. We also offer lung volume reduction surgery or lung transplantation to eligible patients. The Yale COPD program is staffed by two pulmonologists, a pulmonary specialist nurse practitioner, nurses, and respiratory therapists with special expertise in COPD. We arrange visits for patients with other specialist providers as needed, including cardiologists, thoracic surgeons, thoracic oncologists, palliative care specialists, otolaryngologists, allergists/immunologists, sleep medicine specialists, and health psychologists. The Yale COPD Program receives referrals for patients with difficult-to-control symptoms and/or frequent acute disease exacerbations, those who do not respond well to routine medical therapies, those with co-occurring complex medical conditions or overlap syndromes (as detailed above), those who may require surgical therapies, and those who have advanced disease with chronic respiratory failure. Providers in the COPD Program perform comprehensive evaluations and develop individualized care plans for all patients, with the goal of partnering closely with each patient’s primary care and other specialist providers. In addition, opportunities to participate in clinical research trials of new therapies in COPD are often available through our collaboration with the Yale Center for Asthma and Airways Disease (203-500-3808).

At Laboratory Medicine, we study the molecular and cellular components of blood and other body fluids. This work is crucial to diagnosing and managing illness and understanding the mechanisms and origins of disease.Our physicians, known as clinical pathologists, provide consultations to other doctors regarding optimal laboratory diagnostic approaches and the interpretation of complex laboratory tests. Our team includes pathologists, scientists, phlebotomists, medical technicians, technologists, and others who perform important support functions for our state-of-the-art laboratory. We are available every day, 24 hours a day, for physicians. We perform approximately 10 million tests each year, and also provide specialized high-tech testing to other hospitals in the Yale New Haven Health System and institutions throughout New England, and as far away as Puerto Rico. We also operate multiple satellite facilities and patient service centers located throughout the state. We ensure that every test we offer—at every location—is accurate and reliable. When physicians request to have patients’ blood drawn, here is what happens: Collection: A doctor, nurse, technician, or phlebotomist will draw the patient’s blood. Several tubes may be needed for different types of tests. Depending on what illness the patient might have, his or her doctor may want to obtain a urine sample, throat swab, or other sample. After the sample is collected, the container is labeled with the patient’s name and other information. The sample is received and processed by the Laboratory, and testing begins: Chemistry Testing Blood and other bodily fluids are tested for chemicals, drugs, and substances that indicate disease. We check cholesterol and other tests for risk of heart disease, glucose to monitor diabetes, or thyroxin to monitor the thyroid gland. Hematology Testing We analyze the amount and function of blood cells and plasma. Examples include the Complete Blood Count (CBC) that tells the doctor how many cells of each type are in the patient’s blood, and the prothrombin time (PT) to measure the time it takes for the blood to clot. Microbiology Testing We test a variety of specimen samples for infections caused by bacteria, fungi, or parasites. We often do urine cultures for urinary tract infections. Virology Testing We test for viral infections. This includes rapid tests for respiratory viruses such as influenza, molecular tests for noroviruses, and antibody tests for HIV. Immunology/Molecular Diagnostics Some tests are used to determine whether the immune system is functioning properly. State-of-the-art analysis of DNA and RNA is used to test for a variety of diseases and for the risk of developing certain diseases. Other specialized tests include the ANA, used to screen for autoimmune disease, and Factor V Leiden genotyping for patients with blood clots. Tumor Profiling Laboratory This lab analyzes tumor DNA to predict the sensitivity or resistance of tumors to a

We provide preventive and urgent health care to children and adolescents in the greater New Haven community. Our pediatricians work in the Yale New Haven Hospital Pediatric Primary Care Centers at three locations: York Street, St. Raphael campus, and at Chapel Pediatrics in Hamden. We offer routine vaccinations and wellness exams, screening for childhood illness, and positive parenting support and programs. We also have particular expertise in handling conditions that occur during adolescence. Our physicians are highly trained and committed to advocating for children. In our offices, we see children with Husky or commercial insurance, and offer a sliding scale for those without insurance. In our specialty programs, we treat infants and children with a broad range of childhood problems, including: Developmental and behavioral disorders Physical and sexual abuse Rheumatologic conditions, such as arthritis and lupus

At Yale Medicine, our pulmonary, critical care, and sleep medicine physicians focus on your respiratory health. We have a team of specialists to diagnose, treat, and manage respiratory conditions that affect your lungs and breathing. From asthma to complex lung diseases, our goal is to help you breathe easier. Our doctors are board-certified in internal medicine, pulmonary medicine, critical care, and sleep medicine. These expert physicians work closely with specialists in cardiology, diagnostic radiology, and pathology to provide you with comprehensive care for your respiratory condition. Office visits take place at the Winchester Center for Lung Disease in North Haven, Connecticut. Our sleep specialists treat most types of sleep disorders and see patients at our sleep centers at 3 locations in New Haven County. Specialized care is offered in the following areas: Adult cystic fibrosis Asthma and airway diseases Bronchiectasis and chronic pulmonary infections Cardiorespiratory exercise testing Chronic obstructive pulmonary disease (COPD) Clinical research in a wide range of lung diseases Interstitial lung disease Lung cancer screening and pulmonary nodule evaluation Medical intensive care unit for pulmonary conditions Multidisciplinary sleep care Pulmonary embolism Pulmonary function laboratory Pulmonary vascular disease Sleep apnea and other sleep disorders Thoracic interventional pulmonary embolism Thoracic oncology Tuberculosis

Yale Medicine serves as Connecticut’s premier primary immunodeficiency center for pediatric and adult patients. Primary immunodeficiencies, also known as inborn errors of immunity (IEI), present with features involving a disruption of the body’s immune system. The alteration of the immune system can lead to various clinical manifestations, including recurrent infection, autoimmunity, hematopoietic malignancy, lung disease, and enteropathy. These conditions are caused by monogenetic and polygenetic defects or epigenetic changes. We focus on the evaluation, diagnosis, and management of patients with primary immunodeficiency through in-depth genetic and immunological laboratory tests. In addition to patient care, our group works through research to help advance our understanding of immunodeficiency.