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Allergy & Immunology

We provide expert evaluation and treatment to adult and pediatric patients across the entire spectrum of allergic and immunologic disorders. Our board-certified specialists have specific clinical and scientific expertise, and are highly capable of providing comprehensive, thoughtful care from the most common to the rarest conditions. Our physicians meet weekly to discuss the management of complicated cases.

Yale has been the site of several key research breakthroughs in the field during the past decade, including the development of a protective Lyme disease vaccine, crucial understanding of the underlying causes of allergies, and the discovery of new inherited immunological diseases.

Our Services

Our service has specific strength in the management of inherited immune deficiencies, with a dedicated service that closely collaborates with Yale’s stem cell transplant experts. Through a long-standing collaboration with Yale Laboratory Medicine, patients have access to a broad array of state-of-the-art immunological testing.

Among the conditions we treat are:

  • Allergic rhinoconjunctivitis (nasal and eye allergies)
  • Asthma
  • Urticaria (hives)
  • Medication allergy
  • Chronic sinusitis
  • Angioedema
  • Hereditary angioneurotic edema
  • Common variable immunodeficiency
  • Secondary immune deficiencies

We offer a full suite of specialized procedures, including allergy immunotherapy ("allergy shots"), allergy skin testing, antibody replacement therapies, drug desensitization, oral food challenges, and pulmonary function testing. We also offer asthma environmental controls and pharmacological controller therapy, intensive antihistamine regimens, biological therapy for hereditary angioneurotic edema, and intravenous and subcutaneous immunoglobulin replenishment.


Our care for children and adolescents includes treatment for:


Our doctors collaborate with colleagues in the Pediatric Asthma Program to ensure that our patients receive comprehensive asthma care, including:

  • Evaluation, diagnosis, and management of childhood asthma for patients with varying degrees of severity
  • Testing for allergic precipitants
  • Mechanical analysis of respiratory function
  • Outreach care at patients' homes when needed


  • Testing for allergens, desensitization, and immunotherapy
  • Allergic rhinoconjunctivitis
  • Drug allergy
  • Food allergy
  • Insect venom allergy
  • Urticaria (hives), mastocytosis, anaphylaxis
  • Hereditary angioedema

Primary Immunodeficiency and Recurrent Infections

  • Testing for antibody deficiency, cellular immunodeficiency, and complement disorders
  • Treatment of primary immunodeficiency diseases, including intravenous immunoglobulin therapy
  • Evaluation and management of recurrent infections, including fungal infections

Our Programs