Yale Pediatric Nephrology
Yale New Haven Children's Hospital
1 Park Street, Ste West Pavilion - 2nd Floor
New Haven, CT 06504
- Yale Pediatric NephrologyYale New Haven Children's Hospital1 Park Street, Ste West Pavilion - 2nd FloorNew Haven, CT 06504
Julie Goodwin, MD
Pediatrics, Pediatric Nephrology
Make an Appointment OnlineLearn more about telehealth
Telehealth is available
Patient type treated
Child
Accepting new patients
Yes
Referral required
From physicians only
Biography
Julie E. Goodwin, MD, is a pediatric nephrologist who treats broad range of conditions, including hypertension, cystic renal disease and renal transplant.
An assistant professor of pediatrics (nephrology), Dr. Goodwin has been at Yale since 2007. She is a member of the American Society of Pediatric Nephrology, American Society of Nephrology and the Society for Pediatric Research.
Titles
- Associate Professor of Pediatrics (Nephrology)
- Fellowship Program Director
Education & Training
- FellowYale University School of Medicine, New Haven, CT (2007)
- ResidentGeorgetown University Hospital, Washington, DC (2004)
- InternGeorgetown University Hospital, Washington, DC (2002)
- MDBoston University School of Medicine (2001)
Additional Information
Honors & Recognitions
- American Society of Hypertension, Eastern Regional Chapter, Young Investigator's Award, Basic Science Research: American Society of Hypertension (2008)
- Bartner Discovery Scholar Award: (2008)
- 3rd Prize-Pediatric Fellows Research Day: (2007)
- ASN Travel Grant Recipient : (2006)
- 2nd Prize-Pediatric Fellows Research Day: (2006)
- AAP Residency Scholarship Recipient: AAP (2003)
Professional Service
- Make-A-Wish Foundation (2018 - Present): Medical Advisory Council, pediatric nephrology representative
- Scientific Reports (2018 - Present): Editor
- Charles Hood Foundation (2018 - Present): Scientific Review Board
- American Society of Pediatric Nephrology (2015 - Present): Program Planning Committee
- Pediatric Academic Societies (2012 - Present): Abstract Reviewer, Platform Presentation Moderator, Pediatric Academic Socieities Annual Meetings
Publications
- Nugent JT, Reardon J, Crana C, Greenberg JH, Warejko JK, Goodwin JE. Fanconi syndrome, nephrotic-range proteinuria, and hypoalbuminemia in a newborn-Occam's razor or Hickam's dictum? Answers. Pediatric Nephrology (Berlin, Germany) 2022, 37: 129-132. PMID: 34633532, DOI: 10.1007/s00467-021-05255-w.
- Nugent JT, Reardon J, Crana C, Greenberg JH, Warejko JK, Goodwin JE. Fanconi syndrome, nephrotic-range proteinuria, and hypoalbuminemia in a newborn-Occam's razor or Hickam's dictum? Questions. Pediatric Nephrology (Berlin, Germany) 2022, 37: 127-128. PMID: 34633531, DOI: 10.1007/s00467-021-05247-w.
- Srivastava SP, Zhou H, Setia O, Dardik A, Fernandez-Hernando C, Goodwin J. Podocyte Glucocorticoid Receptors Are Essential for Glomerular Endothelial Cell Homeostasis in Diabetes Mellitus. Journal Of The American Heart Association 2021, 10: e019437. PMID: 34308664, PMCID: PMC8475689, DOI: 10.1161/JAHA.120.019437.
- Liu B, Zhou H, Zhang T, Gao X, Tao B, Xing H, Zhuang Z, Dardik A, Kyriakides TR, Goodwin JE. Loss of endothelial glucocorticoid receptor promotes angiogenesis via upregulation of Wnt/β-catenin pathway. Angiogenesis 2021, 24: 631-645. PMID: 33650028, PMCID: PMC8292305, DOI: 10.1007/s10456-021-09773-x.
- Srivastava SP, Srivastava R, Chand S, Goodwin JE. Coronavirus Disease (COVID)-19 and Diabetic Kidney Disease. Pharmaceuticals (Basel, Switzerland) 2021, 14 PMID: 34451848, PMCID: PMC8398861, DOI: 10.3390/ph14080751.
- Srivastava SP, Goodwin JE, Tripathi P, Kanasaki K, Koya D. Interactions among Long Non-Coding RNAs and microRNAs Influence Disease Phenotype in Diabetes and Diabetic Kidney Disease. International Journal Of Molecular Sciences 2021, 22 PMID: 34199672, PMCID: PMC8199750, DOI: 10.3390/ijms22116027.
- Srivastava SP, Li J, Takagaki Y, Kitada M, Goodwin JE, Kanasaki K, Koya D. Endothelial SIRT3 regulates myofibroblast metabolic shifts in diabetic kidneys. IScience 2021, 24: 102390. PMID: 33981977, PMCID: PMC8086030, DOI: 10.1016/j.isci.2021.102390.
- Srivastava SP, Zhou H, Setia O, Liu B, Kanasaki K, Koya D, Dardik A, Fernandez-Hernando C, Goodwin J. Loss of endothelial glucocorticoid receptor accelerates diabetic nephropathy. Nature Communications 2021, 12: 2368. PMID: 33888696, PMCID: PMC8062600, DOI: 10.1038/s41467-021-22617-y.
- Srivastava SP, Kanasaki K, Goodwin JE. Editorial: Combating Diabetes and Diabetic Kidney Disease. Frontiers In Pharmacology 2021, 12: 716029. PMID: 34305620, PMCID: PMC8295890, DOI: 10.3389/fphar.2021.716029.
- Srivastava SP, Goodwin JE, Kanasaki K, Koya D. Metabolic reprogramming by N-acetyl-seryl-aspartyl-lysyl-proline protects against diabetic kidney disease. British Journal Of Pharmacology 2020, 177: 3691-3711. PMID: 32352559, PMCID: PMC7393199, DOI: 10.1111/bph.15087.
- Srivastava SP, Goodwin JE. Cancer Biology and Prevention in Diabetes. Cells 2020, 9 PMID: 32498358, PMCID: PMC7349292, DOI: 10.3390/cells9061380.
- Srivastava SP, Goodwin JE, Kanasaki K, Koya D. Inhibition of Angiotensin-Converting Enzyme Ameliorates Renal Fibrosis by Mitigating DPP-4 Level and Restoring Antifibrotic MicroRNAs. Genes 2020, 11 PMID: 32085655, PMCID: PMC7074526, DOI: 10.3390/genes11020211.
- Zhou H, Mehta S, Srivastava SP, Grabinska K, Zhang X, Wong C, Hedayat A, Perrotta P, Fernández-Hernando C, Sessa WC, Goodwin JE. Endothelial cell-glucocorticoid receptor interactions and regulation of Wnt signaling. JCI Insight 2020, 5 PMID: 32051336, PMCID: PMC7098785, DOI: 10.1172/jci.insight.131384.
- Liu B, Goodwin JE. The Effect of Glucocorticoids on Angiogenesis in the Treatment of Solid Tumors. Journal Of Cellular Signaling 2020, 1: 42-49. PMID: 32728672, PMCID: PMC7388649.
- Srivastava SP, Kanasaki K, Goodwin JE. Loss of Mitochondrial Control Impacts Renal Health. Frontiers In Pharmacology 2020, 11: 543973. PMID: 33362536, PMCID: PMC7756079, DOI: 10.3389/fphar.2020.543973.
- Zhang TN, Yang N, Goodwin JE, Mahrer K, Li D, Xia J, Wen R, Zhou H, Zhang T, Song WL, Liu CF. Characterization of Circular RNA and microRNA Profiles in Septic Myocardial Depression: a Lipopolysaccharide-Induced Rat Septic Shock Model. Inflammation 2019, 42: 1990-2002. PMID: 31332662, DOI: 10.1007/s10753-019-01060-8.
- Liu B, Zhang TN, Knight JK, Goodwin JE. The Glucocorticoid Receptor in Cardiovascular Health and Disease. Cells 2019, 8 PMID: 31601045, PMCID: PMC6829609, DOI: 10.3390/cells8101227.
- Zhang TN, Goodwin JE, Liu B, Li D, Wen R, Yang N, Xia J, Zhou H, Zhang T, Song WL, Liu CF. Characterization of Long Noncoding RNA and mRNA Profiles in Sepsis-Induced Myocardial Depression. Molecular Therapy. Nucleic Acids 2019, 17: 852-866. PMID: 31472370, PMCID: PMC6722300, DOI: 10.1016/j.omtn.2019.07.020.
- Goodwin JE. Role of the glucocorticoid receptor in glomerular disease. American Journal Of Physiology. Renal Physiology 2019, 317: F133-F136. PMID: 31166704, PMCID: PMC6692724, DOI: 10.1152/ajprenal.00217.2019.
- Srivastava SP, Hedayat FA, Kanasaki K, Goodwin JE. microRNA Crosstalk Influences Epithelial-to-Mesenchymal, Endothelial-to-Mesenchymal, and Macrophage-to-Mesenchymal Transitions in the Kidney. Frontiers In Pharmacology 2019, 10: 904. PMID: 31474862, PMCID: PMC6707424, DOI: 10.3389/fphar.2019.00904.
- D'Alessandri-Silva C, Carpenter M, Ayoob R, Barcia J, Chishti A, Constantinescu A, Dell KM, Goodwin J, Hashmat S, Iragorri S, Kaspar C, Mason S, Misurac JM, Muff-Luett M, Sethna C, Shah S, Weng P, Greenbaum LA, Mahan JD. Diagnosis, Treatment, and Outcomes in Children With Congenital Nephrogenic Diabetes Insipidus: A Pediatric Nephrology Research Consortium Study. Frontiers In Pediatrics 2019, 7: 550. PMID: 32039113, PMCID: PMC6985429, DOI: 10.3389/fped.2019.00550.
- Srivastava SP, Li J, Kitada M, Fujita H, Yamada Y, Goodwin JE, Kanasaki K, Koya D. SIRT3 deficiency leads to induction of abnormal glycolysis in diabetic kidney with fibrosis. Cell Death & Disease 2018, 9: 997. PMID: 30250024, PMCID: PMC6155322, DOI: 10.1038/s41419-018-1057-0.
- Zhou H, Tian X, Tufro A, Moeckel G, Ishibe S, Goodwin J. Loss of the podocyte glucocorticoid receptor exacerbates proteinuria after injury. Scientific Reports 2017, 7: 9833. PMID: 28852159, PMCID: PMC5575043, DOI: 10.1038/s41598-017-10490-z.
- Endothelial Dysfunction and Vascular Remodeling in HypertensionGoodwin JE. (2017) Endothelial Dysfunction and Vascular Remodeling in Hypertension. In Flynn J, Ingelfinger JR, Redwine K (Eds.) Pediatric Hypertension, Springer International Publishing AG, DOI: 10.1007/978-3-319-31420-4_41-1
- Goodwin JE, Zhang X, Rotllan N, Feng Y, Zhou H, Fernández-Hernando C, Yu J, Sessa WC. Endothelial glucocorticoid receptor suppresses atherogenesis--brief report. Arteriosclerosis, Thrombosis, And Vascular Biology 2015, 35: 779-782. PMID: 25810297, PMCID: PMC4375730, DOI: 10.1161/ATVBAHA.114.304525.
- Glucocorticoids and the Cardiovascular System. In: Glucocorticoid Signaling: from Molecules to Mice to ManGoodwin JE. Glucocorticoids and the Cardiovascular System. In: Glucocorticoid Signaling: from Molecules to Mice to Man. J Wang, C Harris eds; 2015: 299-314.
- Goodwin JE. Glucocorticoids and the Cardiovascular System. Advances In Experimental Medicine And Biology 2015, 872: 299-314. PMID: 26216000, DOI: 10.1007/978-1-4939-2895-8_13.
- Goodwin JE, Palmer M, Pashankar F, Tufro A, Moeckel G. A 7-year-old boy with renal insufficiency and proteinuria after stem cell transplant for T-cell acute lymphoblastic leukemia. Clinical Nephrology 2014, 82: 205-10. PMID: 23391318, PMCID: PMC6990651, DOI: 10.5414/CN107767.
- Goodwin JE, Feng Y, Velazquez H, Zhou H, Sessa WC. Loss of the endothelial glucocorticoid receptor prevents the therapeutic protection afforded by dexamethasone after LPS. PloS One 2014, 9: e108126. PMID: 25299055, PMCID: PMC4191990, DOI: 10.1371/journal.pone.0108126.
- Bedri B, Goodwin JE. Abdominal distention and renal failure in a neonate. BMJ Case Reports 2013, 2013 PMID: 23429016, PMCID: PMC3604299, DOI: 10.1136/bcr-2012-007955.
- Goodwin JE, Feng Y, Velazquez H, Sessa WC. Endothelial glucocorticoid receptor is required for protection against sepsis. Proceedings Of The National Academy Of Sciences Of The United States Of America 2013, 110: 306-11. PMID: 23248291, PMCID: PMC3538225, DOI: 10.1073/pnas.1210200110.
- Goodwin JE, Geller DS. Glucocorticoid-induced hypertension. Pediatric Nephrology (Berlin, Germany) 2012, 27: 1059-66. PMID: 21744056, DOI: 10.1007/s00467-011-1928-4.
- Goodwin JE, Zhang J, Gonzalez D, Albinsson S, Geller DS. Knockout of the vascular endothelial glucocorticoid receptor abrogates dexamethasone-induced hypertension. Journal Of Hypertension 2011, 29: 1347-56. PMID: 21659825, PMCID: PMC3439131, DOI: 10.1097/HJH.0b013e328347da54.
- Goodwin JE, Zhang J, Velazquez H, Geller DS. The glucocorticoid receptor in the distal nephron is not necessary for the development or maintenance of dexamethasone-induced hypertension. Biochemical And Biophysical Research Communications 2010, 394: 266-71. PMID: 20188070, PMCID: PMC2946623, DOI: 10.1016/j.bbrc.2010.02.123.
- Zhang J, Ge R, Matte-Martone C, Goodwin J, Shlomchik WD, Mamula MJ, Kooshkabadi A, Hardy MP, Geller D. Characterization of a novel gain of function glucocorticoid receptor knock-in mouse. The Journal Of Biological Chemistry 2009, 284: 6249-59. PMID: 19017639, PMCID: PMC2649105, DOI: 10.1074/jbc.M807997200.
- Goodwin JE, Zhang J, Geller DS. A critical role for vascular smooth muscle in acute glucocorticoid-induced hypertension. Journal Of The American Society Of Nephrology : JASN 2008, 19: 1291-9. PMID: 18434569, PMCID: PMC2440298, DOI: 10.1681/ASN.2007080911.
- Monogenic Disorders of Blood Pressure Regulation in Handbook of Hypertension Eds.Goodwin, David Geller. Monogenic Disorders of Blood Pressure Regulation in Handbook of Hypertension Eds.. A. F. Dominiczak and J. M. Connell Vol 24, 29-47. 2007.
Departments and Programs
Locations
Yale Pediatric Nephrology
Yale New Haven Children's Hospital
1 Park Street, Ste West Pavilion - 2nd Floor
New Haven, CT 06504
- Yale Pediatric NephrologyYale New Haven Children's Hospital1 Park Street, Ste West Pavilion - 2nd FloorNew Haven, CT 06504
Biography
Julie E. Goodwin, MD, is a pediatric nephrologist who treats broad range of conditions, including hypertension, cystic renal disease and renal transplant.
An assistant professor of pediatrics (nephrology), Dr. Goodwin has been at Yale since 2007. She is a member of the American Society of Pediatric Nephrology, American Society of Nephrology and the Society for Pediatric Research.
Titles
- Associate Professor of Pediatrics (Nephrology)
- Fellowship Program Director
Education & Training
- FellowYale University School of Medicine, New Haven, CT (2007)
- ResidentGeorgetown University Hospital, Washington, DC (2004)
- InternGeorgetown University Hospital, Washington, DC (2002)
- MDBoston University School of Medicine (2001)
Additional Information
Honors & Recognitions
- American Society of Hypertension, Eastern Regional Chapter, Young Investigator's Award, Basic Science Research: American Society of Hypertension (2008)
- Bartner Discovery Scholar Award: (2008)
- 3rd Prize-Pediatric Fellows Research Day: (2007)
- ASN Travel Grant Recipient : (2006)
- 2nd Prize-Pediatric Fellows Research Day: (2006)
- AAP Residency Scholarship Recipient: AAP (2003)
Professional Service
- Make-A-Wish Foundation (2018 - Present): Medical Advisory Council, pediatric nephrology representative
- Scientific Reports (2018 - Present): Editor
- Charles Hood Foundation (2018 - Present): Scientific Review Board
- American Society of Pediatric Nephrology (2015 - Present): Program Planning Committee
- Pediatric Academic Societies (2012 - Present): Abstract Reviewer, Platform Presentation Moderator, Pediatric Academic Socieities Annual Meetings
Publications
- Nugent JT, Reardon J, Crana C, Greenberg JH, Warejko JK, Goodwin JE. Fanconi syndrome, nephrotic-range proteinuria, and hypoalbuminemia in a newborn-Occam's razor or Hickam's dictum? Answers. Pediatric Nephrology (Berlin, Germany) 2022, 37: 129-132. PMID: 34633532, DOI: 10.1007/s00467-021-05255-w.
- Nugent JT, Reardon J, Crana C, Greenberg JH, Warejko JK, Goodwin JE. Fanconi syndrome, nephrotic-range proteinuria, and hypoalbuminemia in a newborn-Occam's razor or Hickam's dictum? Questions. Pediatric Nephrology (Berlin, Germany) 2022, 37: 127-128. PMID: 34633531, DOI: 10.1007/s00467-021-05247-w.
- Srivastava SP, Zhou H, Setia O, Dardik A, Fernandez-Hernando C, Goodwin J. Podocyte Glucocorticoid Receptors Are Essential for Glomerular Endothelial Cell Homeostasis in Diabetes Mellitus. Journal Of The American Heart Association 2021, 10: e019437. PMID: 34308664, PMCID: PMC8475689, DOI: 10.1161/JAHA.120.019437.
- Liu B, Zhou H, Zhang T, Gao X, Tao B, Xing H, Zhuang Z, Dardik A, Kyriakides TR, Goodwin JE. Loss of endothelial glucocorticoid receptor promotes angiogenesis via upregulation of Wnt/β-catenin pathway. Angiogenesis 2021, 24: 631-645. PMID: 33650028, PMCID: PMC8292305, DOI: 10.1007/s10456-021-09773-x.
- Srivastava SP, Srivastava R, Chand S, Goodwin JE. Coronavirus Disease (COVID)-19 and Diabetic Kidney Disease. Pharmaceuticals (Basel, Switzerland) 2021, 14 PMID: 34451848, PMCID: PMC8398861, DOI: 10.3390/ph14080751.
- Srivastava SP, Goodwin JE, Tripathi P, Kanasaki K, Koya D. Interactions among Long Non-Coding RNAs and microRNAs Influence Disease Phenotype in Diabetes and Diabetic Kidney Disease. International Journal Of Molecular Sciences 2021, 22 PMID: 34199672, PMCID: PMC8199750, DOI: 10.3390/ijms22116027.
- Srivastava SP, Li J, Takagaki Y, Kitada M, Goodwin JE, Kanasaki K, Koya D. Endothelial SIRT3 regulates myofibroblast metabolic shifts in diabetic kidneys. IScience 2021, 24: 102390. PMID: 33981977, PMCID: PMC8086030, DOI: 10.1016/j.isci.2021.102390.
- Srivastava SP, Zhou H, Setia O, Liu B, Kanasaki K, Koya D, Dardik A, Fernandez-Hernando C, Goodwin J. Loss of endothelial glucocorticoid receptor accelerates diabetic nephropathy. Nature Communications 2021, 12: 2368. PMID: 33888696, PMCID: PMC8062600, DOI: 10.1038/s41467-021-22617-y.
- Srivastava SP, Kanasaki K, Goodwin JE. Editorial: Combating Diabetes and Diabetic Kidney Disease. Frontiers In Pharmacology 2021, 12: 716029. PMID: 34305620, PMCID: PMC8295890, DOI: 10.3389/fphar.2021.716029.
- Srivastava SP, Goodwin JE, Kanasaki K, Koya D. Metabolic reprogramming by N-acetyl-seryl-aspartyl-lysyl-proline protects against diabetic kidney disease. British Journal Of Pharmacology 2020, 177: 3691-3711. PMID: 32352559, PMCID: PMC7393199, DOI: 10.1111/bph.15087.
- Srivastava SP, Goodwin JE. Cancer Biology and Prevention in Diabetes. Cells 2020, 9 PMID: 32498358, PMCID: PMC7349292, DOI: 10.3390/cells9061380.
- Srivastava SP, Goodwin JE, Kanasaki K, Koya D. Inhibition of Angiotensin-Converting Enzyme Ameliorates Renal Fibrosis by Mitigating DPP-4 Level and Restoring Antifibrotic MicroRNAs. Genes 2020, 11 PMID: 32085655, PMCID: PMC7074526, DOI: 10.3390/genes11020211.
- Zhou H, Mehta S, Srivastava SP, Grabinska K, Zhang X, Wong C, Hedayat A, Perrotta P, Fernández-Hernando C, Sessa WC, Goodwin JE. Endothelial cell-glucocorticoid receptor interactions and regulation of Wnt signaling. JCI Insight 2020, 5 PMID: 32051336, PMCID: PMC7098785, DOI: 10.1172/jci.insight.131384.
- Liu B, Goodwin JE. The Effect of Glucocorticoids on Angiogenesis in the Treatment of Solid Tumors. Journal Of Cellular Signaling 2020, 1: 42-49. PMID: 32728672, PMCID: PMC7388649.
- Srivastava SP, Kanasaki K, Goodwin JE. Loss of Mitochondrial Control Impacts Renal Health. Frontiers In Pharmacology 2020, 11: 543973. PMID: 33362536, PMCID: PMC7756079, DOI: 10.3389/fphar.2020.543973.
- Zhang TN, Yang N, Goodwin JE, Mahrer K, Li D, Xia J, Wen R, Zhou H, Zhang T, Song WL, Liu CF. Characterization of Circular RNA and microRNA Profiles in Septic Myocardial Depression: a Lipopolysaccharide-Induced Rat Septic Shock Model. Inflammation 2019, 42: 1990-2002. PMID: 31332662, DOI: 10.1007/s10753-019-01060-8.
- Liu B, Zhang TN, Knight JK, Goodwin JE. The Glucocorticoid Receptor in Cardiovascular Health and Disease. Cells 2019, 8 PMID: 31601045, PMCID: PMC6829609, DOI: 10.3390/cells8101227.
- Zhang TN, Goodwin JE, Liu B, Li D, Wen R, Yang N, Xia J, Zhou H, Zhang T, Song WL, Liu CF. Characterization of Long Noncoding RNA and mRNA Profiles in Sepsis-Induced Myocardial Depression. Molecular Therapy. Nucleic Acids 2019, 17: 852-866. PMID: 31472370, PMCID: PMC6722300, DOI: 10.1016/j.omtn.2019.07.020.
- Goodwin JE. Role of the glucocorticoid receptor in glomerular disease. American Journal Of Physiology. Renal Physiology 2019, 317: F133-F136. PMID: 31166704, PMCID: PMC6692724, DOI: 10.1152/ajprenal.00217.2019.
- Srivastava SP, Hedayat FA, Kanasaki K, Goodwin JE. microRNA Crosstalk Influences Epithelial-to-Mesenchymal, Endothelial-to-Mesenchymal, and Macrophage-to-Mesenchymal Transitions in the Kidney. Frontiers In Pharmacology 2019, 10: 904. PMID: 31474862, PMCID: PMC6707424, DOI: 10.3389/fphar.2019.00904.
- D'Alessandri-Silva C, Carpenter M, Ayoob R, Barcia J, Chishti A, Constantinescu A, Dell KM, Goodwin J, Hashmat S, Iragorri S, Kaspar C, Mason S, Misurac JM, Muff-Luett M, Sethna C, Shah S, Weng P, Greenbaum LA, Mahan JD. Diagnosis, Treatment, and Outcomes in Children With Congenital Nephrogenic Diabetes Insipidus: A Pediatric Nephrology Research Consortium Study. Frontiers In Pediatrics 2019, 7: 550. PMID: 32039113, PMCID: PMC6985429, DOI: 10.3389/fped.2019.00550.
- Srivastava SP, Li J, Kitada M, Fujita H, Yamada Y, Goodwin JE, Kanasaki K, Koya D. SIRT3 deficiency leads to induction of abnormal glycolysis in diabetic kidney with fibrosis. Cell Death & Disease 2018, 9: 997. PMID: 30250024, PMCID: PMC6155322, DOI: 10.1038/s41419-018-1057-0.
- Zhou H, Tian X, Tufro A, Moeckel G, Ishibe S, Goodwin J. Loss of the podocyte glucocorticoid receptor exacerbates proteinuria after injury. Scientific Reports 2017, 7: 9833. PMID: 28852159, PMCID: PMC5575043, DOI: 10.1038/s41598-017-10490-z.
- Endothelial Dysfunction and Vascular Remodeling in HypertensionGoodwin JE. (2017) Endothelial Dysfunction and Vascular Remodeling in Hypertension. In Flynn J, Ingelfinger JR, Redwine K (Eds.) Pediatric Hypertension, Springer International Publishing AG, DOI: 10.1007/978-3-319-31420-4_41-1
- Goodwin JE, Zhang X, Rotllan N, Feng Y, Zhou H, Fernández-Hernando C, Yu J, Sessa WC. Endothelial glucocorticoid receptor suppresses atherogenesis--brief report. Arteriosclerosis, Thrombosis, And Vascular Biology 2015, 35: 779-782. PMID: 25810297, PMCID: PMC4375730, DOI: 10.1161/ATVBAHA.114.304525.
- Glucocorticoids and the Cardiovascular System. In: Glucocorticoid Signaling: from Molecules to Mice to ManGoodwin JE. Glucocorticoids and the Cardiovascular System. In: Glucocorticoid Signaling: from Molecules to Mice to Man. J Wang, C Harris eds; 2015: 299-314.
- Goodwin JE. Glucocorticoids and the Cardiovascular System. Advances In Experimental Medicine And Biology 2015, 872: 299-314. PMID: 26216000, DOI: 10.1007/978-1-4939-2895-8_13.
- Goodwin JE, Palmer M, Pashankar F, Tufro A, Moeckel G. A 7-year-old boy with renal insufficiency and proteinuria after stem cell transplant for T-cell acute lymphoblastic leukemia. Clinical Nephrology 2014, 82: 205-10. PMID: 23391318, PMCID: PMC6990651, DOI: 10.5414/CN107767.
- Goodwin JE, Feng Y, Velazquez H, Zhou H, Sessa WC. Loss of the endothelial glucocorticoid receptor prevents the therapeutic protection afforded by dexamethasone after LPS. PloS One 2014, 9: e108126. PMID: 25299055, PMCID: PMC4191990, DOI: 10.1371/journal.pone.0108126.
- Bedri B, Goodwin JE. Abdominal distention and renal failure in a neonate. BMJ Case Reports 2013, 2013 PMID: 23429016, PMCID: PMC3604299, DOI: 10.1136/bcr-2012-007955.
- Goodwin JE, Feng Y, Velazquez H, Sessa WC. Endothelial glucocorticoid receptor is required for protection against sepsis. Proceedings Of The National Academy Of Sciences Of The United States Of America 2013, 110: 306-11. PMID: 23248291, PMCID: PMC3538225, DOI: 10.1073/pnas.1210200110.
- Goodwin JE, Geller DS. Glucocorticoid-induced hypertension. Pediatric Nephrology (Berlin, Germany) 2012, 27: 1059-66. PMID: 21744056, DOI: 10.1007/s00467-011-1928-4.
- Goodwin JE, Zhang J, Gonzalez D, Albinsson S, Geller DS. Knockout of the vascular endothelial glucocorticoid receptor abrogates dexamethasone-induced hypertension. Journal Of Hypertension 2011, 29: 1347-56. PMID: 21659825, PMCID: PMC3439131, DOI: 10.1097/HJH.0b013e328347da54.
- Goodwin JE, Zhang J, Velazquez H, Geller DS. The glucocorticoid receptor in the distal nephron is not necessary for the development or maintenance of dexamethasone-induced hypertension. Biochemical And Biophysical Research Communications 2010, 394: 266-71. PMID: 20188070, PMCID: PMC2946623, DOI: 10.1016/j.bbrc.2010.02.123.
- Zhang J, Ge R, Matte-Martone C, Goodwin J, Shlomchik WD, Mamula MJ, Kooshkabadi A, Hardy MP, Geller D. Characterization of a novel gain of function glucocorticoid receptor knock-in mouse. The Journal Of Biological Chemistry 2009, 284: 6249-59. PMID: 19017639, PMCID: PMC2649105, DOI: 10.1074/jbc.M807997200.
- Goodwin JE, Zhang J, Geller DS. A critical role for vascular smooth muscle in acute glucocorticoid-induced hypertension. Journal Of The American Society Of Nephrology : JASN 2008, 19: 1291-9. PMID: 18434569, PMCID: PMC2440298, DOI: 10.1681/ASN.2007080911.
- Monogenic Disorders of Blood Pressure Regulation in Handbook of Hypertension Eds.Goodwin, David Geller. Monogenic Disorders of Blood Pressure Regulation in Handbook of Hypertension Eds.. A. F. Dominiczak and J. M. Connell Vol 24, 29-47. 2007.
Departments and Programs
Locations
Yale Pediatric Nephrology
Yale New Haven Children's Hospital
1 Park Street, Ste West Pavilion - 2nd Floor
New Haven, CT 06504
- Yale Pediatric NephrologyYale New Haven Children's Hospital1 Park Street, Ste West Pavilion - 2nd FloorNew Haven, CT 06504
Yale Pediatric Nephrology
Yale New Haven Children's Hospital
1 Park Street, Ste West Pavilion - 2nd Floor
New Haven, CT 06504
- Yale Pediatric NephrologyYale New Haven Children's Hospital1 Park Street, Ste West Pavilion - 2nd FloorNew Haven, CT 06504