Dhanpat Jain, MD
Pathology, Anatomic Pathology, GI & Liver Pathology
Telehealth is available
Patient type treated
Adult
Accepting new patients
No
Referral required
From physicians only
Board Certified in
Anatomic Pathology
Biography
Dhanpat Jain, MD, is a pathologist specializing in gastrointestinal (GI) and liver diseases and cancers. Before he graduated high school, Dr. Jain knew he would pursue a career in medicine. Not until later in his medical training did he discover that he could apply his interests in visual art and pattern recognition to a field like pathology. “It is a natural fit for me,” Dr. Jain says.
On a daily basis, Dr. Jain examines tissue samples and biopsies from patients with suspected GI and liver diseases. He has extensive experience with samples that reflect motility, or movement, disorders of the GI tract. “These are uncommon disorders and not many people examine cases like this,” Dr. Jain says. For this reason, he regularly consults with physicians and other pathologists across the globe on challenging cases.
As a professor of pathology and of medicine (digestive diseases) at Yale School of Medicine, Dr. Jain researches liver tumors, inflammatory bowel disease, and cancers related to the liver and digestive tract.
Titles
- Professor of Pathology and of Medicine (Digestive Diseases)
Education & Training
- ResidentYale University School of Medicine (1999)
- ResidentYale University School of Medicine (1998)
- FellowYale University School of Medicine (1996)
- Senior ResidentPost Graduate Institute of Medical Education and Research (1994)
- ResidentPost Graduate Institute of Medical Education and Research (1991)
- MDPost Graduate Institute of Medical Education and Research, Chandigarh, India, Pathology (1989)
- MDMysore Medical College (1986)
Languages Spoken
- বাংলা (Bengali)
- English
- हिन्दी (Hindi)
Additional Information
Honors & Recognitions
- Averill A. Liebow Award: Department of Pathology (2014)
- Billing Compliance leader of the year: YMG (2005)
- Howard Spiro Award: Section of Digestive Diseases (2003)
- Averill A. Liebow Award: Department of Pathology (2000)
Board Certifications
- AB of Pathology, Anatomic Pathology (1998)
Professional Service
- College of American Pathologists (2022 - 2023): Committee Member
Publications
- Lam R, Tarangelo N, Wang R, Horibe M, Grimshaw AA, Jain D, Haffar S, Bazerbachi F, Kunz PL, Li DK. Microangiopathic Hemolytic Anemia Is a Late and Fatal Complication of Gastric Signet Ring Cell Carcinoma: A Systematic Review and Case-Control Study. The Oncologist 2022, 27: 751-759. PMID: 35589098, PMCID: PMC9438916, DOI: 10.1093/oncolo/oyac093.
- Madoff DC, Abi-Jaoudeh N, Braxton D, Goyal L, Jain D, Odisio BC, Salem R, Schattner M, Sheth R, Li D. An Expert, Multidisciplinary Perspective on Best Practices in Biomarker Testing in Intrahepatic Cholangiocarcinoma. The Oncologist 2022 PMID: 35925597, DOI: 10.1093/oncolo/oyac139.
- Mirza H, Besse W, Somlo S, Weinreb J, Kenney B, Jain D. An Update on Ductal Plate Malformations and Fibropolycystic Diseases of the Liver. Human Pathology 2022 PMID: 35777701, DOI: 10.1016/j.humpath.2022.06.022.
- Zhang X, Jain D. The many faces and pathologic diagnostic challenges of autoimmune hepatitis. Human Pathology 2022 PMID: 35753409, DOI: 10.1016/j.humpath.2022.06.019.
- Wang D, González IA, Russo PA, Jain D, Zhang X. Prominent Pseudoacini in Focal Nodular Hyperplasia: A Potential Diagnostic Pitfall. The American Journal Of Surgical Pathology 2022 PMID: 35749760, DOI: 10.1097/PAS.0000000000001931.
- Lerch JM, Pai RK, Brown I, Gill AJ, Jain D, Kővári B, Kushima R, Sheahan K, Slavik T, Srivastava A, Lauwers GY, Langner C. Interobserver agreement of estimating the extent of intestinal metaplasia in patients with chronic atrophic gastritis. Virchows Archiv : An International Journal Of Pathology 2022, 480: 1277-1281. PMID: 34904185, PMCID: PMC9184363, DOI: 10.1007/s00428-021-03245-9.
- Yasir S, Chen ZE, Jain D, Kakar S, Wu TT, Yeh MM, Torbenson MS. Hepatic Adenomas in Patients 60 and Older Are Enriched for HNF1A Inactivation and Malignant Transformation. The American Journal Of Surgical Pathology 2022, 46: 786-792. PMID: 35383587, DOI: 10.1097/PAS.0000000000001892.
- Wang JD, Sebastian C, Walther Z, Suresh T, Lacy J, Zhang X, Jain D. An Appraisal of Immunohistochemical Stain Use in Hepatic Metastasis Highlights the Effectiveness of the Individualized, Case-Based Approach. Archives Of Pathology & Laboratory Medicine 2022 PMID: 35512224, DOI: 10.5858/arpa.2021-0457-OA.
- Lohse AW, Sebode M, Bhathal PS, Clouston AD, Dienes HP, Jain D, Gouw ASH, Guindi M, Kakar S, Kleiner DE, Krech T, Lackner C, Longerich T, Saxena R, Terracciano L, Washington K, Weidemann S, Hübscher SG, Tiniakos D. Consensus recommendations for histological criteria of autoimmune hepatitis from the International AIH Pathology Group: Results of a workshop on AIH histology hosted by the European Reference Network on Hepatological Diseases and the European Society of Pathology: Results of a workshop on AIH histology hosted by the European Reference Network on Hepatological Diseases and the European Society of Pathology. Liver International : Official Journal Of The International Association For The Study Of The Liver 2022, 42: 1058-1069. PMID: 35230735, DOI: 10.1111/liv.15217.
- Lerch JM, Pai RK, Brown I, Gill AJ, Jain D, Kővári B, Kushima R, Sheahan K, Slavik T, Srivastava A, Lauwers GY, Langner C. Subtyping intestinal metaplasia in patients with chronic atrophic gastritis: an interobserver variability study. Pathology 2022, 54: 262-268. PMID: 35221041, DOI: 10.1016/j.pathol.2021.12.288.
- Bhat N, Esteghamat F, Chaube BK, Gunawardhana K, Mani M, Thames C, Jain D, Ginsberg HN, Fernandes-Hernando C, Mani A. TCF7L2 transcriptionally regulates Fgf15 to maintain bile acid and lipid homeostasis through gut-liver crosstalk. FASEB Journal : Official Publication Of The Federation Of American Societies For Experimental Biology 2022, 36: e22185. PMID: 35133032, DOI: 10.1096/fj.202101607R.
- Jain A, Mazer B, Deng Y, Ciarleglio M, Jain D, Taddei T, Zhang X. Hepatocellular Carcinoma: Does the Background Liver With or Without Cirrhosis Matter? American Journal Of Clinical Pathology 2022, 157: 305-313. PMID: 34542582, DOI: 10.1093/ajcp/aqab125.
- Li H, Zhang X, Finberg KE, Walther Z, Jain D, Gibson J. Pathogenic BRCA2 germline variants in combined hepatocellular-cholangiocarcinoma. Pathology International 2022, 72: 138-140. PMID: 34808016, DOI: 10.1111/pin.13188.
- Bhat N, Narayanan A, Fathzadeh M, Kahn M, Zhang D, Goedeke L, Neogi A, Cardone RL, Kibbey RG, Fernandez-Hernando C, Ginsberg HN, Jain D, Shulman G, Mani A. Dyrk1b promotes hepatic lipogenesis by bypassing canonical insulin signaling and directly activating mTORC2 in mice. The Journal Of Clinical Investigation 2022, 132 PMID: 34855620, PMCID: PMC8803348, DOI: 10.1172/JCI153724.
- Ugwu N, Atzmony L, Ellis KT, Panse G, Jain D, Ko CJ, Nassiri N, Choate KA. Erratum: Cutaneous and hepatic vascular lesions due to a recurrent somatic GJA4 mutation reveal a pathway for vascular malformation. HGG Advances 2022, 3: 100061. PMID: 35047851, PMCID: PMC8756555, DOI: 10.1016/j.xhgg.2021.100061.
- Patil PA, Taddei T, Jain D, Zhang X. HNF-1β is a More Sensitive and Specific Marker Than C-Reactive Protein for Identifying Biliary Differentiation in Primary Hepatic Carcinomas. Archives Of Pathology & Laboratory Medicine 2022, 146: 220-226. PMID: 34086854, DOI: 10.5858/arpa.2020-0725-OA.
- Pacheco MC, Torbenson MS, Wu TT, Kakar S, Jain D, Yeh MM. Pediatric Hepatocellular Adenomas: The Influence of Age and Syndrome on Subtype. The American Journal Of Surgical Pathology 2021, 45: 1641-1647. PMID: 34148984, PMCID: PMC8608351, DOI: 10.1097/PAS.0000000000001763.
- Jain D, Sreenivasan P, Inayat I, Deng Y, Ciarleglio MM, Garcia-Tsao G. Thick Fibrous Septa on Liver Biopsy Specimens Predict the Development of Decompensation in Patients With Compensated Cirrhosis. American Journal Of Clinical Pathology 2021, 156: 802-809. PMID: 33940622, PMCID: PMC8512277, DOI: 10.1093/ajcp/aqab024.
- Wen KW, Joseph NM, Srivastava A, Saunders TA, Jain D, Rank J, Feely M, Zarrinpar A, Al Diffalha S, Shyn PB, Graham RP, Drage MG, Kakar S. Inhibin-positive hepatic carcinoma: proposal for a solid-tubulocystic variant of intrahepatic cholangiocarcinoma. Human Pathology 2021, 116: 82-93. PMID: 34298064, DOI: 10.1016/j.humpath.2021.07.004.
- Yan K, Hung A, Parmer C, Yang H, Jain D, Lim B, Goodman AL, Garcia-Tsao G. Obeticholic Acid Decreases Intestinal Content of Enterococcus in Rats With Cirrhosis and Ascites. Hepatology Communications 2021, 5: 1507-1517. PMID: 34510838, PMCID: PMC8435275, DOI: 10.1002/hep4.1740.
- Rottmann BG, Patel N, Ahmed M, Deng Y, Ciarleglio M, Vyas M, Jain D, Zhang X. Clinicopathological significance of neutrophil-rich colorectal carcinoma. Journal Of Clinical Pathology 2021 PMID: 34312298, DOI: 10.1136/jclinpath-2021-207702.
- Drzewiecki K, Choi J, Brancale J, Leney-Greene MA, Sari S, Dalgiç B, Ünlüsoy Aksu A, Evirgen Şahin G, Ozen A, Baris S, Karakoc-Aydiner E, Jain D, Kleiner D, Schmalz M, Radhakrishnan K, Zhang J, Hoebe K, Su HC, Pereira JP, Lenardo MJ, Lifton RP, Vilarinho S. GIMAP5 maintains liver endothelial cell homeostasis and prevents portal hypertension. The Journal Of Experimental Medicine 2021, 218 PMID: 33956074, PMCID: PMC8105721, DOI: 10.1084/jem.20201745.
- Kumar D, Hafez O, Jain D, Zhang X. Can primary hepatocellular carcinoma histomorphology predict extrahepatic metastasis? Human Pathology 2021, 113: 39-46. PMID: 33905775, DOI: 10.1016/j.humpath.2021.04.008.
- Lu SX, Huang YH, Liu LL, Zhang CZ, Yang X, Yang YZ, Shao CK, Li JM, Xie D, Zhang X, Jain D, Yun JP. α-Fetoprotein mRNA in situ hybridisation is a highly specific marker of hepatocellular carcinoma: a multi-centre study. British Journal Of Cancer 2021, 124: 1988-1996. PMID: 33824478, PMCID: PMC8184895, DOI: 10.1038/s41416-021-01363-4.
- Vyas M, Jain D. An update on subtypes of hepatocellular carcinoma: From morphology to molecular. Indian Journal Of Pathology & Microbiology 2021, 64: S112-S120. PMID: 34135152, DOI: 10.4103/IJPM.IJPM_751_20.
- Ugwu N, Atzmony L, Ellis KT, Panse G, Jain D, Ko CJ, Nassiri N, Choate KA. Cutaneous and hepatic vascular lesions due to a recurrent somatic GJA4 mutation reveal a pathway for vascular malformation. HGG Advances 2021, 2 PMID: 33912852, PMCID: PMC8078848, DOI: 10.1016/j.xhgg.2021.100028.
- Celli R, Saffo S, Kamili S, Wiese N, Hayden T, Taddei T, Jain D. Liver Pathologic Changes After Direct-Acting Antiviral Agent Therapy and Sustained Virologic Response in the Setting of Chronic Hepatitis C Virus Infection. Archives Of Pathology & Laboratory Medicine 2021, 145: 419-427. PMID: 32810870, DOI: 10.5858/arpa.2020-0008-OA.
- Cheng L, Jain D, Kakar S, Torbenson MS, Wu TT, Yeh MM. Hepatocellular neoplasms arising in genetic metabolic disorders: steatosis is common in both the tumor and background liver. Human Pathology 2021, 108: 93-99. PMID: 33245984, DOI: 10.1016/j.humpath.2020.11.012.
- Tefera J, Revzin M, Chapiro J, Savic L, Mulligan D, Batra R, Taddei T, Jain D, Zhang X. Fibronodular hepatocellular carcinoma-a new variant of liver cancer: clinical, pathological and radiological correlation. Journal Of Clinical Pathology 2021, 74: 31-35. PMID: 32430483, PMCID: PMC7674234, DOI: 10.1136/jclinpath-2020-206574.
- Jain D, Torres R, Celli R, Koelmel J, Charkoftaki G, Vasiliou V. Evolution of the liver biopsy and its future. Translational Gastroenterology And Hepatology 2021, 6: 20. PMID: 33824924, PMCID: PMC7829074, DOI: 10.21037/tgh.2020.04.01.
- Zhang X, Jain D. Updates in staging and pathologic evaluation of esophageal carcinoma following neoadjuvant therapy. Annals Of The New York Academy Of Sciences 2020, 1482: 163-176. PMID: 32892349, DOI: 10.1111/nyas.14462.
- Vyas M, Celli R, Singh M, Patel N, Aslanian HR, Boffa D, Deng Y, Ciarleglio MM, Laine L, Jain D. Intestinal metaplasia around the gastroesophageal junction is frequently associated with antral reactive gastropathy: implications for carcinoma at the gastroesophageal junction. Human Pathology 2020, 105: 67-73. PMID: 32941964, DOI: 10.1016/j.humpath.2020.08.007.
- Odio CD, O'Brien CR, Jacox J, Jain D, Lee AI. Cryptic Cachexia. The New England Journal Of Medicine 2020, 383: 68-74. PMID: 32609985, DOI: 10.1056/NEJMcps1817531.
- Gao E, Cheema H, Waheed N, Mushtaq I, Erden N, Nelson-Williams C, Jain D, Soroka CJ, Boyer JL, Khalil Y, Clayton PT, Mistry PK, Lifton RP, Vilarinho S. Organic Solute Transporter Alpha Deficiency: A Disorder With Cholestasis, Liver Fibrosis, and Congenital Diarrhea. Hepatology (Baltimore, Md.) 2020, 71: 1879-1882. PMID: 31863603, PMCID: PMC8577800, DOI: 10.1002/hep.31087.
- Roulis M, Kaklamanos A, Schernthanner M, Bielecki P, Zhao J, Kaffe E, Frommelt LS, Qu R, Knapp MS, Henriques A, Chalkidi N, Koliaraki V, Jiao J, Brewer JR, Bacher M, Blackburn HN, Zhao X, Breyer RM, Aidinis V, Jain D, Su B, Herschman HR, Kluger Y, Kollias G, Flavell RA. Paracrine orchestration of intestinal tumorigenesis by a mesenchymal niche. Nature 2020, 580: 524-529. PMID: 32322056, PMCID: PMC7490650, DOI: 10.1038/s41586-020-2166-3.
- Johncilla M, Grover S, Zhang X, Jain D, Srivastava A. Morphological spectrum of immune check-point inhibitor therapy-associated gastritis. Histopathology 2020, 76: 531-539. PMID: 31692018, DOI: 10.1111/his.14029.
- Ueasilamongkol P, Khamphaya T, Guerra MT, Rodrigues M, Gomes DA, Kong Y, Wei W, Jain D, Trampert DC, Ananthanarayanan M, Banales JM, Roberts LR, Farshidfar F, Nathanson MH, Weerachayaphorn J. Type 3 Inositol 1,4,5-Trisphosphate Receptor Is Increased and Enhances Malignant Properties in Cholangiocarcinoma. Hepatology (Baltimore, Md.) 2020, 71: 583-599. PMID: 31251815, PMCID: PMC6934938, DOI: 10.1002/hep.30839.
- Patel N, Vyas M, Celli R, Jain D, Zhang X. Adverse Histologic Features in Colorectal Nonpedunculated Malignant Polyps With Nodal Metastasis. The American Journal Of Surgical Pathology 2020, 44: 241-246. PMID: 31498179, DOI: 10.1097/PAS.0000000000001369.
- Olave MC, Gurung A, Mistry PK, Kakar S, Yeh M, Xu M, Wu TT, Torbenson M, Jain D. Etiology of cirrhosis in the young. Human Pathology 2020, 96: 96-103. PMID: 31698008, DOI: 10.1016/j.humpath.2019.09.015.
- Guo Y, Jain D, Weinreb J. Von Meyenburg Complex: Current Concepts and Imaging Misconceptions. Journal Of Computer Assisted Tomography 2019, 43: 846-851. PMID: 31356525, DOI: 10.1097/RCT.0000000000000904.
- Nalbantoglu I, Jain D. Cryptogenic cirrhosis: Old and new perspectives in the era of molecular and genomic medicine. Seminars In Diagnostic Pathology 2019, 36: 389-394. PMID: 31395291, DOI: 10.1053/j.semdp.2019.07.003.
- Pai RK, Kleiner DE, Hart J, Adeyi OA, Clouston AD, Behling CA, Jain D, Kakar S, Brahmania M, Burgart L, Batts KP, Valasek MA, Torbenson MS, Guindi M, Wang HL, Ajmera V, Adams LA, Parker CE, Feagan BG, Loomba R, Jairath V. Standardising the interpretation of liver biopsies in non-alcoholic fatty liver disease clinical trials. Alimentary Pharmacology & Therapeutics 2019, 50: 1100-1111. PMID: 31583739, PMCID: PMC6817398, DOI: 10.1111/apt.15503.
- Balitzer D, Joseph NM, Ferrell L, Shafizadeh N, Jain D, Zhang X, Yeh M, di Tommaso L, Kakar S. Immunohistochemical and molecular features of cholangiolocellular carcinoma are similar to well-differentiated intrahepatic cholangiocarcinoma. Modern Pathology : An Official Journal Of The United States And Canadian Academy Of Pathology, Inc 2019, 32: 1486-1494. PMID: 31186529, DOI: 10.1038/s41379-019-0290-0.
- Beech C, Freedman-Weiss M, Salem R, Jain D, Zhang X. Pancreatic Intraductal Papillary Mucinous Neoplasm With Elevated Pre-Operative Cystic Carcinoembryonic Antigen Level: A Histopathologic Correlation. Gastroenterology Research 2019, 12: 185-190. PMID: 31523327, PMCID: PMC6731045, DOI: 10.14740/gr1201.
- Morin-Zorman S, Wysocki C, Zhu J, Li H, Zorman S, Matte-Martone C, Kisanga E, McNiff J, Jain D, Gonzalez D, Rothstein DM, Lakkis FG, Haberman A, Shlomchik WD. In vivo dynamics of T cells and their interactions with dendritic cells in mouse cutaneous graft-versus-host disease. Blood Advances 2019, 3: 2082-2092. PMID: 31296496, PMCID: PMC6650737, DOI: 10.1182/bloodadvances.2019000227.
- Arnold CA, Graham RP, Jain D, Kakar S, Lam-Himlin DM, Naini BV, Wu TT, Yeh MM, Torbenson MS. Knowledge gaps in the appendix: a multi-institutional study from seven academic centers. Modern Pathology : An Official Journal Of The United States And Canadian Academy Of Pathology, Inc 2019, 32: 988-996. PMID: 30765881, DOI: 10.1038/s41379-019-0216-x.
- Jeon Y, Benedict M, Taddei T, Jain D, Zhang X. Macrotrabecular Hepatocellular Carcinoma: An Aggressive Subtype of Hepatocellular Carcinoma. The American Journal Of Surgical Pathology 2019, 43: 943-948. PMID: 31135484, DOI: 10.1097/PAS.0000000000001289.
- Hakim A, Zhang X, DeLisle A, Oral EA, Dykas D, Drzewiecki K, Assis DN, Silveira M, Batisti J, Jain D, Bale A, Mistry PK, Vilarinho S. Clinical utility of genomic analysis in adults with idiopathic liver disease. Journal Of Hepatology 2019, 70: 1214-1221. PMID: 31000363, PMCID: PMC6526061, DOI: 10.1016/j.jhep.2019.01.036.
- Vyas M, Patel N, Celli R, Wajapeyee N, Jain D, Zhang X. Glucose Metabolic Reprogramming and Cell Proliferation Arrest in Colorectal Micropapillary Carcinoma. Gastroenterology Research 2019, 12: 128-134. PMID: 31236153, PMCID: PMC6575135, DOI: 10.14740/gr1145.
- Torbenson MS, Arnold CA, Graham RP, Jain D, Kakar S, Lam-Himlin DM, Naini BV, Wu TT, Yeh M. Identification of key challenges in liver pathology: data from a multicenter study of extramural consults. Human Pathology 2019, 87: 75-82. PMID: 30857968, DOI: 10.1016/j.humpath.2019.03.001.
- Ünlüsoy Aksu A, Das SK, Nelson-Williams C, Jain D, Özbay Hoşnut F, Evirgen Şahin G, Lifton RP, Vilarinho S. Recessive Mutations in KIF12 Cause High Gamma-Glutamyltransferase Cholestasis. Hepatology Communications 2019, 3: 471-477. PMID: 30976738, PMCID: PMC6442693, DOI: 10.1002/hep4.1320.
- Codina A, Renauer PA, Wang G, Chow RD, Park JJ, Ye H, Zhang K, Dong MB, Gassaway B, Ye L, Errami Y, Shen L, Chang A, Jain D, Herbst RS, Bosenberg M, Rinehart J, Fan R, Chen S. Convergent Identification and Interrogation of Tumor-Intrinsic Factors that Modulate Cancer Immunity In Vivo. Cell Systems 2019, 8: 136-151.e7. PMID: 30797773, PMCID: PMC6592847, DOI: 10.1016/j.cels.2019.01.004.
- Celli R, Tang LH, Cai G, Freedman-Weiss M, Colunga M, Salem RR, Majumdar S, Jain D. Proinsulin Expressing Neuroendocrine Tumors of the Pancreas: An Underrecognized Entity. Pancreas 2019, 48: 55-59. PMID: 30451800, DOI: 10.1097/MPA.0000000000001196.
- Gurung A, Assis DN, McCarty TR, Mitchell KA, Boyer JL, Jain D. Histologic features of autoimmune hepatitis: a critical appraisal. Human Pathology 2018, 82: 51-60. PMID: 30041025, DOI: 10.1016/j.humpath.2018.07.014.
- Sari S, Dalgic B, Muehlenbachs A, DeLeon-Carnes M, Goldsmith CS, Ekinci O, Jain D, Keating MK, Vilarinho S. Prototheca zopfii Colitis in Inherited CARD9 Deficiency. The Journal Of Infectious Diseases 2018, 218: 485-489. PMID: 29659908, PMCID: PMC6049027, DOI: 10.1093/infdis/jiy198.
- Benedict MA, Lauwers GY, Jain D. Gastric Adenocarcinoma of the Fundic Gland Type: Update and Literature Review. American Journal Of Clinical Pathology 2018, 149: 461-473. PMID: 29648578, DOI: 10.1093/ajcp/aqy019.
- Manfredo Vieira S, Hiltensperger M, Kumar V, Zegarra-Ruiz D, Dehner C, Khan N, Costa FRC, Tiniakou E, Greiling T, Ruff W, Barbieri A, Kriegel C, Mehta SS, Knight JR, Jain D, Goodman AL, Kriegel MA. Translocation of a gut pathobiont drives autoimmunity in mice and humans. Science (New York, N.Y.) 2018, 359: 1156-1161. PMID: 29590047, PMCID: PMC5959731, DOI: 10.1126/science.aar7201.
- Vyas M, Jain D. A practical diagnostic approach to hepatic masses. Indian Journal Of Pathology & Microbiology 2018, 61: 2-17. PMID: 29567877, DOI: 10.4103/IJPM.IJPM_578_17.
- Graham RP, Yeh MM, Lam-Himlin D, Roberts LR, Terracciano L, Cruise MW, Greipp PT, Zreik RT, Jain D, Zaid N, Salaria SN, Jin L, Wang X, Rustin JG, Kerr SE, Sukov WR, Solomon DA, Kakar S, Waterhouse E, Gill RM, Ferrell L, Alves VA, Nart D, Yilmaz F, Roessler S, Longerich T, Schirmacher P, Torbenson MS. Molecular testing for the clinical diagnosis of fibrolamellar carcinoma. Modern Pathology : An Official Journal Of The United States And Canadian Academy Of Pathology, Inc 2018, 31: 141-149. PMID: 28862261, PMCID: PMC5758901, DOI: 10.1038/modpathol.2017.103.
- Zhang X, Zhu H, Yang X, Adsay VN, Jain D. Post-obstructive cyst formation in pancreas and cystic acinar transformation: Are they same? Pathology, Research And Practice 2017, 213: 997-1001. PMID: 28599853, DOI: 10.1016/j.prp.2017.03.013.
- Murtha TD, Lupsa BC, Majumdar S, Jain D, Salem RR. A Systematic Review of Proinsulin-Secreting Pancreatic Neuroendocrine Tumors. Journal Of Gastrointestinal Surgery : Official Journal Of The Society For Surgery Of The Alimentary Tract 2017, 21: 1335-1341. PMID: 28510792, DOI: 10.1007/s11605-017-3428-8.
- Lawless ME, Toweill DL, Jewell KD, Jain D, Lamps L, Krasinskas AM, Swanson PE, Upton MP, Yeh MM. Massive Gastric Juvenile Polyposis: A Clinicopathologic Study Using SMAD4 Immunohistochemistry. American Journal Of Clinical Pathology 2017, 147: 390. PMID: 28340255, DOI: 10.1093/ajcp/aqx015.
- Cai SY, Ouyang X, Chen Y, Soroka CJ, Wang J, Mennone A, Wang Y, Mehal WZ, Jain D, Boyer JL. Bile acids initiate cholestatic liver injury by triggering a hepatocyte-specific inflammatory response. JCI Insight 2017, 2: e90780. PMID: 28289714, PMCID: PMC5333973, DOI: 10.1172/jci.insight.90780.
- Bartley AN, Washington MK, Colasacco C, Ventura CB, Ismaila N, Benson AB, Carrato A, Gulley ML, Jain D, Kakar S, Mackay HJ, Streutker C, Tang L, Troxell M, Ajani JA. HER2 Testing and Clinical Decision Making in Gastroesophageal Adenocarcinoma: Guideline From the College of American Pathologists, American Society for Clinical Pathology, and the American Society of Clinical Oncology. Journal Of Clinical Oncology : Official Journal Of The American Society Of Clinical Oncology 2017, 35: 446-464. PMID: 28129524, DOI: 10.1200/JCO.2016.69.4836.
- Bartley AN, Washington MK, Ventura CB, Ismaila N, Colasacco C, Benson AB, Carrato A, Gulley ML, Jain D, Kakar S, Mackay HJ, Streutker C, Tang L, Troxell M, Ajani JA. HER2 Testing and Clinical Decision Making in Gastroesophageal Adenocarcinoma: Guideline From the College of American Pathologists, American Society for Clinical Pathology, and American Society of Clinical Oncology. Archives Of Pathology & Laboratory Medicine 2016, 140: 1345-1363. PMID: 27841667, DOI: 10.5858/arpa.2016-0331-CP.
- Celli R, Colunga M, Patel N, Djekidel M, Jain D. Metabolic Signature on 18F-FDG PET/CT, HER2 Status, and Survival in Gastric Adenocarcinomas. Journal Of Nuclear Medicine Technology 2016, 44: 234-238. PMID: 27789750, DOI: 10.2967/jnmt.116.181479.
- Bartley AN, Washington MK, Ventura CB, Ismaila N, Colasacco C, Benson AB, Carrato A, Gulley ML, Jain D, Kakar S, Mackay HJ, Streutker C, Tang L, Troxell M, Ajani JA. HER2 Testing and Clinical Decision Making in Gastroesophageal Adenocarcinoma: Guideline From the College of American Pathologists, American Society for Clinical Pathology, and American Society of Clinical Oncology. American Journal Of Clinical Pathology 2016, 146: 647-669. PMID: 28077399, PMCID: PMC6272805, DOI: 10.1093/ajcp/aqw206.
- Vilarinho S, Sari S, Mazzacuva F, Bilgüvar K, Esendagli-Yilmaz G, Jain D, Akyol G, Dalgiç B, Günel M, Clayton PT, Lifton RP. ACOX2 deficiency: A disorder of bile acid synthesis with transaminase elevation, liver fibrosis, ataxia, and cognitive impairment. Proceedings Of The National Academy Of Sciences Of The United States Of America 2016, 113: 11289-11293. PMID: 27647924, PMCID: PMC5056113, DOI: 10.1073/pnas.1613228113.
- Binder HJ, Jain D. Does Increased Duodenal Intraepithelial Lymphocytosis Always Equate With Marsh 1 Lesion? Journal Of Clinical Gastroenterology 2016, 50: 613-4. PMID: 27509445, DOI: 10.1097/MCG.0000000000000562.
- Lu H, Wang T, Li J, Fedele C, Liu Q, Zhang J, Jiang Z, Jain D, Iozzo RV, Violette SM, Weinreb PH, Davis RJ, Gioeli D, FitzGerald TJ, Altieri DC, Languino LR. αvβ6 Integrin Promotes Castrate-Resistant Prostate Cancer through JNK1-Mediated Activation of Androgen Receptor. Cancer Research 2016, 76: 5163-74. PMID: 27450452, PMCID: PMC5012867, DOI: 10.1158/0008-5472.CAN-16-0543.
- Bernardo RM, Gurung A, Jain D, Malinis MF. Therapeutic Challenges of Hepatic Mucormycosis in Hematologic Malignancy: A Case Report and Review of the Literature. The American Journal Of Case Reports 2016, 17: 484-9. PMID: 27406045, PMCID: PMC4948661, DOI: 10.12659/ajcr.898480.
- Vilarinho S, Sari S, Yilmaz G, Stiegler AL, Boggon TJ, Jain D, Akyol G, Dalgic B, Günel M, Lifton RP. Recurrent recessive mutation in deoxyguanosine kinase causes idiopathic noncirrhotic portal hypertension. Hepatology (Baltimore, Md.) 2016, 63: 1977-86. PMID: 26874653, PMCID: PMC4874872, DOI: 10.1002/hep.28499.
- Host factors are dominant in the development of post-liver transplant non-alcoholic steatohepatitis.Boga S, Munoz-Abraham AS, Rodriguez-Davalos MI, Emre SH, Jain D, Schilsky ML. Host factors are dominant in the development of post-liver transplant non-alcoholic steatohepatitis. World Journal Of Hepatology 2016, 8: 659-64. PMID: 27239259, PMCID: PMC4876289, DOI: 10.4254/wjh.v8.i15.659.
- Monestime G, Borger DK, Kim J, Lopez G, Allgaeuer M, Jain D, Vortmeyer A, Wang HW, Sidransky E. Varied autopsy findings in five treated patients with Gaucher disease and parkinsonism include the absence of Gaucher cells. Molecular Genetics And Metabolism 2016, 118: 55-9. PMID: 26992326, DOI: 10.1016/j.ymgme.2016.02.008.
- Zhang Z, Jain D, Brand M. Ringed Esophagus Secondary to Lymphocytic Esophagitis. Gastroenterology & Hepatology 2016, 12: 237-9. PMID: 27231454, PMCID: PMC4872853.
- Vyas M, Zhang X, Morrow JS, Jain D, Salem RR, West AB. Focal hepatic glycogenosis associated with metastatic insulinoma presenting as mass lesions. Pathology, Research And Practice 2016, 212: 59-62. PMID: 26627264, DOI: 10.1016/j.prp.2015.11.006.
- Valika AK, Jain D, Jaffe PE, Moeckel G, Brewster UC. A Nodular Foreign Body Reaction in a Dialysis Patient Receiving Long-term Treatment With Lanthanum Carbonate. American Journal Of Kidney Diseases : The Official Journal Of The National Kidney Foundation 2016, 67: 128-32. PMID: 26385816, DOI: 10.1053/j.ajkd.2015.07.033.
- Boga S, Jain D, Schilsky ML. Trientine induced colitis during therapy for Wilson disease: a case report and review of the literature. BMC Pharmacology & Toxicology 2015, 16: 30. PMID: 26589720, PMCID: PMC4654910, DOI: 10.1186/s40360-015-0031-z.
- Boga S, Jain D, Schilsky ML. Presentation of Progressive Familial Intrahepatic Cholestasis Type 3 Mimicking Wilson Disease: Molecular Genetic Diagnosis and Response to Treatment. Pediatric Gastroenterology, Hepatology & Nutrition 2015, 18: 202-8. PMID: 26473142, PMCID: PMC4600706, DOI: 10.5223/pghn.2015.18.3.202.
- Nguyen T, Phillips D, Jain D, Torbenson M, Wu TT, Yeh MM, Kakar S. Comparison of 5 Immunohistochemical Markers of Hepatocellular Differentiation for the Diagnosis of Hepatocellular Carcinoma. Archives Of Pathology & Laboratory Medicine 2015, 139: 1028-34. PMID: 26230595, DOI: 10.5858/arpa.2014-0479-OA.
- Balakrishnan M, Garcia-Tsao G, Deng Y, Ciarleglio M, Jain D. Hepatic arteriolosclerosis: a small-vessel complication of diabetes and hypertension. The American Journal Of Surgical Pathology 2015, 39: 1000-9. PMID: 25786083, PMCID: PMC4466001, DOI: 10.1097/PAS.0000000000000419.
- Tuktamyshov R, Jain D, Ginsburg PM. Recurrence of Merkel cell carcinoma in the gastrointestinal tract: a case report. BMC Research Notes 2015, 8: 188. PMID: 25947008, PMCID: PMC4430924, DOI: 10.1186/s13104-015-1139-3.
- Sethi A, Jain D, Roland BC, Kinzel J, Gibson J, Schrader R, Hanson JA. Performing colonic mast cell counts in patients with chronic diarrhea of unknown etiology has limited diagnostic use. Archives Of Pathology & Laboratory Medicine 2015, 139: 225-32. PMID: 25611105, DOI: 10.5858/arpa.2013-0594-OA.
- Kakar S, Torbenson M, Jain D, Wu TT, Yeh M, Ferrell LD. Immunohistochemical pitfalls in the diagnosis of hepatocellular adenomas and focal nodular hyperplasia: accurate understanding of diverse staining patterns is essential for diagnosis and risk assessment. Modern Pathology : An Official Journal Of The United States And Canadian Academy Of Pathology, Inc 2015, 28: 159-60. PMID: 25560413, DOI: 10.1038/modpathol.2014.121.
- Vilarinho S, Choi M, Jain D, Malhotra A, Kulkarni S, Pashankar D, Phatak U, Patel M, Bale A, Mane S, Lifton RP, Mistry PK. Individual exome analysis in diagnosis and management of paediatric liver failure of indeterminate aetiology. Journal Of Hepatology 2014, 61: 1056-63. PMID: 25016221, PMCID: PMC4203706, DOI: 10.1016/j.jhep.2014.06.038.
- Mistry PK, Liu J, Sun L, Chuang WL, Yuen T, Yang R, Lu P, Zhang K, Li J, Keutzer J, Stachnik A, Mennone A, Boyer JL, Jain D, Brady RO, New MI, Zaidi M. Glucocerebrosidase 2 gene deletion rescues type 1 Gaucher disease. Proceedings Of The National Academy Of Sciences Of The United States Of America 2014, 111: 4934-9. PMID: 24639522, PMCID: PMC3977292, DOI: 10.1073/pnas.1400768111.
- Chen J, Wong S, Nathanson MH, Jain D. Evaluation of Barrett esophagus by multiphoton microscopy. Archives Of Pathology & Laboratory Medicine 2014, 138: 204-12. PMID: 24476518, PMCID: PMC4089503, DOI: 10.5858/arpa.2012-0675-OA.
- Joseph NM, Ferrell LD, Jain D, Torbenson MS, Wu TT, Yeh MM, Kakar S. Diagnostic utility and limitations of glutamine synthetase and serum amyloid-associated protein immunohistochemistry in the distinction of focal nodular hyperplasia and inflammatory hepatocellular adenoma. Modern Pathology : An Official Journal Of The United States And Canadian Academy Of Pathology, Inc 2014, 27: 62-72. PMID: 23807780, DOI: 10.1038/modpathol.2013.114.
- Gunal A, Hui P, Kilic S, Xu R, Jain D, Mitchell K, Robert M, Kenney B. KRAS mutations are associated with specific morphologic features in colon cancer. Journal Of Clinical Gastroenterology 2013, 47: 509-14. PMID: 23090042, DOI: 10.1097/MCG.0b013e3182703030.
- Krings G, Ramachandran R, Jain D, Wu TT, Yeh MM, Torbenson M, Kakar S. Immunohistochemical pitfalls and the importance of glypican 3 and arginase in the diagnosis of scirrhous hepatocellular carcinoma. Modern Pathology : An Official Journal Of The United States And Canadian Academy Of Pathology, Inc 2013, 26: 782-91. PMID: 23348905, DOI: 10.1038/modpathol.2012.243.
- Bedossa P, Garcia-Tsao G, Jain D. Cirrhosis Regression and Subclassification. Surgical Pathology Clinics 2013, 6: 295-309. PMID: 26838976, DOI: 10.1016/j.path.2013.03.006.
- Kakar S, Jain D. Liver Pathology: Unraveling the Art of Pattern Recognition. Surgical Pathology Clinics 2013, 6: ix-x. PMID: 26838980, DOI: 10.1016/j.path.2013.03.009.
- Marginean EC, Gown AM, Jain D. Diagnostic Approach to Hepatic Mass Lesions and Role of Immunohistochemistry. Surgical Pathology Clinics 2013, 6: 333-65. PMID: 26838978, DOI: 10.1016/j.path.2013.03.005.
- Morotti RA, Jain D. Pediatric Cholestatic Disorders: Approach to Pathologic Diagnosis. Surgical Pathology Clinics 2013, 6: 205-25. PMID: 26838972, DOI: 10.1016/j.path.2013.03.001.
- Liu J, Halene S, Yang M, Iqbal J, Yang R, Mehal WZ, Chuang WL, Jain D, Yuen T, Sun L, Zaidi M, Mistry PK. Gaucher disease gene GBA functions in immune regulation. Proceedings Of The National Academy Of Sciences Of The United States Of America 2012, 109: 10018-23. PMID: 22665763, PMCID: PMC3382552, DOI: 10.1073/pnas.1200941109.
- Lo SM, Choi M, Liu J, Jain D, Boot RG, Kallemeijn WW, Aerts JM, Pashankar F, Kupfer GM, Mane S, Lifton RP, Mistry PK. Phenotype diversity in type 1 Gaucher disease: discovering the genetic basis of Gaucher disease/hematologic malignancy phenotype by individual genome analysis. Blood 2012, 119: 4731-40. PMID: 22493294, PMCID: PMC3367875, DOI: 10.1182/blood-2011-10-386862.
- Singhi AD, Jain D, Kakar S, Wu TT, Yeh MM, Torbenson M. Reticulin loss in benign fatty liver: an important diagnostic pitfall when considering a diagnosis of hepatocellular carcinoma. The American Journal Of Surgical Pathology 2012, 36: 710-5. PMID: 22498821, DOI: 10.1097/PAS.0b013e3182495c73.
- Chan ES, Alexander J, Swanson PE, Jain D, Yeh MM. PDX-1, CDX-2, TTF-1, and CK7: a reliable immunohistochemical panel for pancreatic neuroendocrine neoplasms. The American Journal Of Surgical Pathology 2012, 36: 737-43. PMID: 22498824, DOI: 10.1097/PAS.0b013e31824aba59.
- Sethasine S, Jain D, Groszmann RJ, Garcia-Tsao G. Quantitative histological-hemodynamic correlations in cirrhosis. Hepatology (Baltimore, Md.) 2012, 55: 1146-53. PMID: 22109744, PMCID: PMC3721182, DOI: 10.1002/hep.24805.
- Aslanian H, Chander B, Robert M, Cooper D, Proctor D, Seropian S, Jain D. Prospective evaluation of acute graft-versus-host disease. Digestive Diseases And Sciences 2012, 57: 720-5. PMID: 22011927, DOI: 10.1007/s10620-011-1938-x.
- Barbieri AL, Jain D, Gobel S, Kenney B. Wagner-Meissner corpuscle proliferation: a unique cause of colon polyps. International Journal Of Surgical Pathology 2012, 20: 79-82. PMID: 21632642, DOI: 10.1177/1066896911408723.
- Cheng SX, Gathungu G, Pashankar D, Jain D, Husain SZ. Jejunal adaptation in a prepubertal boy after total ileal resection and jejunostomy placement: a four-year follow-up. Journal Of Clinical Gastroenterology 2011, 45: 846-9. PMID: 21552141, PMCID: PMC4425287, DOI: 10.1097/MCG.0b013e318214b2d9.
- Anderson BE, Tang AL, Wang Y, Froicu M, Rothstein D, McNiff JM, Jain D, Demetris AJ, Farber DL, Shlomchik WD, Shlomchik MJ. Enhancing alloreactivity does not restore GVHD induction but augments skin graft rejection by CD4⁺ effector memory T cells. European Journal Of Immunology 2011, 41: 2782-92. PMID: 21660940, PMCID: PMC3517133, DOI: 10.1002/eji.201141678.
- Gancayco J, Siddiqui UD, Jain D, Aslanian HR. Narrow band imaging features and pathological correlations of sessile serrated polyps. The American Journal Of Gastroenterology 2011, 106: 1559-60. PMID: 21811282, DOI: 10.1038/ajg.2011.122.
- Kenney B, Singh G, Salem RR, Paterno F, Robert ME, Jain D. Pseudointraductal papillary mucinous neoplasia caused by microscopic periductal endocrine tumors of the pancreas: a report of 3 cases. Human Pathology 2011, 42: 1034-41. PMID: 21292301, DOI: 10.1016/j.humpath.2010.09.018.
- Zeng H, Yu H, Lu L, Jain D, Kidd MS, Saif MW, Chanock SJ, Hartge P, Risch HA. Genetic effects and modifiers of radiotherapy and chemotherapy on survival in pancreatic cancer. Pancreas 2011, 40: 657-63. PMID: 21487324, PMCID: PMC3116071, DOI: 10.1097/MPA.0b013e31821268d1.
- Walther Z, Jain D. Molecular pathology of hepatic neoplasms: classification and clinical significance. Pathology Research International 2011, 2011: 403929. PMID: 21559202, PMCID: PMC3090128, DOI: 10.4061/2011/403929.
- Chander B, Fiedler P, Jain D. Eosinophilic myenteric ganglionitis: a case of intestinal pseudo-obstruction in a 93-year-old female. Journal Of Clinical Gastroenterology 2011, 45: 314-6. PMID: 20921901, DOI: 10.1097/MCG.0b013e3181f5978a.
- Li H, Matte-Martone C, Tan HS, Venkatesan S, McNiff J, Demetris AJ, Jain D, Lakkis F, Rothstein D, Shlomchik WD. Graft-versus-host disease is independent of innate signaling pathways triggered by pathogens in host hematopoietic cells. Journal Of Immunology (Baltimore, Md. : 1950) 2011, 186: 230-41. PMID: 21098219, PMCID: PMC5822434, DOI: 10.4049/jimmunol.1002965.
- Mistry PK, Liu J, Yang M, Nottoli T, McGrath J, Jain D, Zhang K, Keutzer J, Chuang WL, Mehal WZ, Zhao H, Lin A, Mane S, Liu X, Peng YZ, Li JH, Agrawal M, Zhu LL, Blair HC, Robinson LJ, Iqbal J, Sun L, Zaidi M. Glucocerebrosidase gene-deficient mouse recapitulates Gaucher disease displaying cellular and molecular dysregulation beyond the macrophage. Proceedings Of The National Academy Of Sciences Of The United States Of America 2010, 107: 19473-8. PMID: 20962279, PMCID: PMC2984187, DOI: 10.1073/pnas.1003308107.
- Matte-Martone C, Wang X, Anderson B, Jain D, Demetris AJ, McNiff J, Shlomchik MJ, Shlomchik WD. Recipient B cells are not required for graft-versus-host disease induction. Biology Of Blood And Marrow Transplantation : Journal Of The American Society For Blood And Marrow Transplantation 2010, 16: 1222-30. PMID: 20338255, PMCID: PMC3135976, DOI: 10.1016/j.bbmt.2010.03.015.
- Parkash V, Bifulco C, Feinn R, Concato J, Jain D. To count and how to count, that is the question: interobserver and intraobserver variability among pathologists in lymph node counting. American Journal Of Clinical Pathology 2010, 134: 42-9. PMID: 20551265, DOI: 10.1309/AJCPO92DZMUCGEUF.
- Stein P, Yu H, Jain D, Mistry PK. Hyperferritinemia and iron overload in type 1 Gaucher disease. American Journal Of Hematology 2010, 85: 472-6. PMID: 20575041, PMCID: PMC2895498, DOI: 10.1002/ajh.21721.
- Orabi AI, Shah AU, Ahmad MU, Choo-Wing R, Parness J, Jain D, Bhandari V, Husain SZ. Dantrolene mitigates caerulein-induced pancreatitis in vivo in mice. American Journal Of Physiology. Gastrointestinal And Liver Physiology 2010, 299: G196-204. PMID: 20448143, PMCID: PMC2904115, DOI: 10.1152/ajpgi.00498.2009.
- Lo SM, Stein P, Mullaly S, Bar M, Jain D, Pastores GM, Mistry PK. Expanding spectrum of the association between Type 1 Gaucher disease and cancers: a series of patients with up to 3 sequential cancers of multiple types--correlation with genotype and phenotype. American Journal Of Hematology 2010, 85: 340-5. PMID: 20425796, PMCID: PMC2875938, DOI: 10.1002/ajh.21684.
- Jain D, Ahrens W, Finkelstein S. Molecular evidence for the neoplastic potential of hepatic Von-Meyenburg complexes. Applied Immunohistochemistry & Molecular Morphology : AIMM / Official Publication Of The Society For Applied Immunohistochemistry 2010, 18: 166-71. PMID: 19770706, DOI: 10.1097/PAI.0b013e3181b94fd8.
- Van Patten K, Parkash V, Jain D. Cadherin expression in gastrointestinal tract endometriosis: possible role in deep tissue invasion and development of malignancy. Modern Pathology : An Official Journal Of The United States And Canadian Academy Of Pathology, Inc 2010, 23: 38-44. PMID: 19898423, DOI: 10.1038/modpathol.2009.127.
- Phatak UP, Seo-Mayer P, Jain D, Selbst M, Husain S, Pashankar DS. Mycophenolate mofetil-induced colitis in children. Journal Of Clinical Gastroenterology 2009, 43: 967-9. PMID: 19609219, DOI: 10.1097/MCG.0b013e3181a8754d.
- Shah AU, Sarwar A, Orabi AI, Gautam S, Grant WM, Park AJ, Shah AU, Liu J, Mistry PK, Jain D, Husain SZ. Protease activation during in vivo pancreatitis is dependent on calcineurin activation. American Journal Of Physiology. Gastrointestinal And Liver Physiology 2009, 297: G967-73. PMID: 20501444, PMCID: PMC2777459, DOI: 10.1152/ajpgi.00181.2009.
- Kakar S, Chen X, Ho C, Burgart LJ, Adeyi O, Jain D, Sahai V, Ferrell LD. Chromosomal abnormalities determined by comparative genomic hybridization are helpful in the diagnosis of atypical hepatocellular neoplasms. Histopathology 2009, 55: 197-205. PMID: 19694827, PMCID: PMC3727398, DOI: 10.1111/j.1365-2559.2009.03343.x.
- Selbst MK, Ahrens WA, Robert ME, Friedman A, Proctor DD, Jain D. Spectrum of histologic changes in colonic biopsies in patients treated with mycophenolate mofetil. Modern Pathology : An Official Journal Of The United States And Canadian Academy Of Pathology, Inc 2009, 22: 737-43. PMID: 19329937, DOI: 10.1038/modpathol.2009.44.
- Zheng H, Matte-Martone C, Jain D, McNiff J, Shlomchik WD. Central memory CD8+ T cells induce graft-versus-host disease and mediate graft-versus-leukemia. Journal Of Immunology (Baltimore, Md. : 1950) 2009, 182: 5938-48. PMID: 19414745, DOI: 10.4049/jimmunol.0802212.
- Concato J, Jain D, Uchio E, Risch H, Li WW, Wells CK. Molecular markers and death from prostate cancer. Annals Of Internal Medicine 2009, 150: 595-603. PMID: 19414838, DOI: 10.7326/0003-4819-150-9-200905050-00005.
- Hakim W, Sheikh S, Inayat I, Caldwell C, Smith D, Lorber M, Friedman A, Jain D, Bia M, Formica R, Mehal W. HCV response in patients with end stage renal disease treated with combination pegylated interferon alpha-2a and ribavirin. Journal Of Clinical Gastroenterology 2009, 43: 477-81. PMID: 19142165, PMCID: PMC3715868, DOI: 10.1097/MCG.0b013e318180803a.
- Kamath A, Helie M, Bifulco CB, Li WW, Concato J, Jain D. Lack of immunohistochemical detection of VEGF in prostate carcinoma. Applied Immunohistochemistry & Molecular Morphology : AIMM / Official Publication Of The Society For Applied Immunohistochemistry 2009, 17: 227-32. PMID: 19098681, DOI: 10.1097/PAI.0b013e31818f9e7f.
- Ahmad I, Iyer A, Marginean CE, Yeh MM, Ferrell L, Qin L, Bifulco CB, Jain D. Diagnostic use of cytokeratins, CD34, and neuronal cell adhesion molecule staining in focal nodular hyperplasia and hepatic adenoma. Human Pathology 2009, 40: 726-34. PMID: 19157505, DOI: 10.1016/j.humpath.2008.10.018.
- Kakar S, Chen X, Ho C, Burgart LJ, Sahai V, Dachrut S, Yabes A, Jain D, Ferrell LD. Chromosomal changes in fibrolamellar hepatocellular carcinoma detected by array comparative genomic hybridization. Modern Pathology : An Official Journal Of The United States And Canadian Academy Of Pathology, Inc 2009, 22: 134-41. PMID: 18997738, DOI: 10.1038/modpathol.2008.178.
- Rogart JN, Jain D, Siddiqui UD, Oren T, Lim J, Jamidar P, Aslanian H. Narrow-band imaging without high magnification to differentiate polyps during real-time colonoscopy: improvement with experience. Gastrointestinal Endoscopy 2008, 68: 1136-45. PMID: 18691708, DOI: 10.1016/j.gie.2008.04.035.
- Zipprich A, Loureiro-Silva MR, Jain D, D'Silva I, Groszmann RJ. Nitric oxide and vascular remodeling modulate hepatic arterial vascular resistance in the isolated perfused cirrhotic rat liver. Journal Of Hepatology 2008, 49: 739-45. PMID: 18804307, DOI: 10.1016/j.jhep.2008.06.027.
- Kamath A, Mehal W, Jain D. Colchicine-associated ring mitosis in liver biopsy and their clinical implications. Journal Of Clinical Gastroenterology 2008, 42: 1060-2. PMID: 18391833, PMCID: PMC3730132, DOI: 10.1097/MCG.0b013e31803815b4.
- Kenney BC, Jain D. Identification of lymphatics within the colonic lamina propria in inflammation and neoplasia using the monoclonal antibody D2-40. The Yale Journal Of Biology And Medicine 2008, 81: 103-13. PMID: 18827885, PMCID: PMC2553648.
- Iyer A, Robert ME, Bifulco CB, Salem RR, Jain D. Different cytokeratin and neuronal cell adhesion molecule staining patterns in focal nodular hyperplasia and hepatic adenoma and their significance. Human Pathology 2008, 39: 1370-7. PMID: 18602664, PMCID: PMC3738023, DOI: 10.1016/j.humpath.2008.01.015.
- Kenney B, Tormey CA, Qin L, Sosa JA, Jain D, Neto A. Adult nesidioblastosis. Clinicopathologic correlation between pre-operative selective arterial calcium stimulation studies and post-operative pathologic findings. JOP : Journal Of The Pancreas 2008, 9: 504-11. PMID: 18648143.
- Chetty R, Jain D, Serra S. p120 catenin reduction and cytoplasmic relocalization leads to dysregulation of E-cadherin in solid pseudopapillary tumors of the pancreas. American Journal Of Clinical Pathology 2008, 130: 71-6. PMID: 18550473, DOI: 10.1309/FEYD99TXC4LMYVA5.
- Anderson BE, Taylor PA, McNiff JM, Jain D, Demetris AJ, Panoskaltsis-Mortari A, Ager A, Blazar BR, Shlomchik WD, Shlomchik MJ. Effects of donor T-cell trafficking and priming site on graft-versus-host disease induction by naive and memory phenotype CD4 T cells. Blood 2008, 111: 5242-51. PMID: 18285547, PMCID: PMC2384145, DOI: 10.1182/blood-2007-09-107953.
- Matte-Martone C, Liu J, Jain D, McNiff J, Shlomchik WD. CD8+ but not CD4+ T cells require cognate interactions with target tissues to mediate GVHD across only minor H antigens, whereas both CD4+ and CD8+ T cells require direct leukemic contact to mediate GVL. Blood 2008, 111: 3884-92. PMID: 18223170, PMCID: PMC2275040, DOI: 10.1182/blood-2007-11-125294.
- Carmack S, Taddei T, Robert ME, Mistry P, Jain D. Increased T-cell sinusoidal lymphocytosis in liver biopsies in patients with chronic hepatitis C and mixed cryoglobulinemia. The American Journal Of Gastroenterology 2008, 103: 705-11. PMID: 17970837, DOI: 10.1111/j.1572-0241.2007.01603.x.
- Zheng H, Matte-Martone C, Li H, Anderson BE, Venketesan S, Sheng Tan H, Jain D, McNiff J, Shlomchik WD. Effector memory CD4+ T cells mediate graft-versus-leukemia without inducing graft-versus-host disease. Blood 2008, 111: 2476-84. PMID: 18045967, PMCID: PMC2234071, DOI: 10.1182/blood-2007-08-109678.
- Gallagher AR, Esquivel EL, Briere TS, Tian X, Mitobe M, Menezes LF, Markowitz GS, Jain D, Onuchic LF, Somlo S. Biliary and pancreatic dysgenesis in mice harboring a mutation in Pkhd1. The American Journal Of Pathology 2008, 172: 417-29. PMID: 18202188, PMCID: PMC2312372, DOI: 10.2353/ajpath.2008.070381.
- Anderson BE, Zheng H, Taylor PA, Matte-Martone C, McNiff JM, Jain D, Demetris AJ, Panoskaltsis-Mortari A, Ager A, Blazar BR, Shlomchik MJ, Shlomchik WD. Memory T cells in GVHD and GVL. Biology Of Blood And Marrow Transplantation : Journal Of The American Society For Blood And Marrow Transplantation 2008, 14: 19-20. PMID: 19418622.
- Concato J, Jain D, Li WW, Risch HA, Uchio EM, Wells CK. Molecular markers and mortality in prostate cancer. BJU International 2007, 100: 1259-63. PMID: 17850375, DOI: 10.1111/j.1464-410X.2007.07136.x.
- Dranoff JA, Kruglov EA, Abreu-Lanfranco O, Nguyen T, Arora G, Jain D. Prevention of liver fibrosis by the purinoceptor antagonist pyridoxal-phosphate-6-azophenyl-2',4'-disulfonate (PPADS). In Vivo (Athens, Greece) 2007, 21: 957-65. PMID: 18210741.
- Neto AG, Dainiak C, Qin L, Salem RR, Jain D. Intraductal papillary cholangiocarcinoma associated with von Meyenberg complexes: a case report. Digestive Diseases And Sciences 2007, 52: 2643-5. PMID: 17394067, DOI: 10.1007/s10620-007-9777-5.
- Marginean EC, Bennick M, Cyczk J, Robert ME, Jain D. Gastric siderosis: patterns and significance. The American Journal Of Surgical Pathology 2006, 30: 514-20. PMID: 16625099, DOI: 10.1097/00000478-200604000-00013.
- Nagula S, Jain D, Groszmann RJ, Garcia-Tsao G. Histological-hemodynamic correlation in cirrhosis-a histological classification of the severity of cirrhosis. Journal Of Hepatology 2006, 44: 111-7. PMID: 16274836, DOI: 10.1016/j.jhep.2005.07.036.
- Kakar S, Burgart LJ, Batts KP, Garcia J, Jain D, Ferrell LD. Clinicopathologic features and survival in fibrolamellar carcinoma: comparison with conventional hepatocellular carcinoma with and without cirrhosis. Modern Pathology : An Official Journal Of The United States And Canadian Academy Of Pathology, Inc 2005, 18: 1417-23. PMID: 15920538, DOI: 10.1038/modpathol.3800449.
- Jain D, Eslami-Varzaneh F, Takano AM, Ayer U, Umashankar R, Muller R, Klimstra DS. Composite glandular and endocrine tumors of the stomach with pancreatic acinar differentiation. The American Journal Of Surgical Pathology 2005, 29: 1524-9. PMID: 16224221, DOI: 10.1097/01.pas.0000169498.89035.f9.
- Sheela H, Seela S, Caldwell C, Boyer JL, Jain D. Liver biopsy: evolving role in the new millennium. Journal Of Clinical Gastroenterology 2005, 39: 603-10. PMID: 16000929, DOI: 10.1097/01.mcg.0000170742.59134.60.
- Mariappan MR, Fadare O, Jain D, Chacho MS. Diagnostic intraoperative imprint cytology of a solid pseudopapillary tumor of the pancreas. Diagnostic Cytopathology 2005, 32: 351-2. PMID: 15880718, DOI: 10.1002/dc.20194.
- Achneck HE, Wong IY, Kim PJ, Fernandes MA, Walther Z, Seymour NE, Jain D. Ileostomy adenocarcinomas in the setting of ulcerative colitis. Journal Of Clinical Gastroenterology 2005, 39: 396-400. PMID: 15815208, DOI: 10.1097/01.mcg.0000159216.39795.4a.
- Anderson BE, McNiff JM, Jain D, Blazar BR, Shlomchik WD, Shlomchik MJ. Distinct roles for donor- and host-derived antigen-presenting cells and costimulatory molecules in murine chronic graft-versus-host disease: requirements depend on target organ. Blood 2005, 105: 2227-34. PMID: 15522961, DOI: 10.1182/blood-2004-08-3032.
- Dranoff JA, Kruglov EA, Toure J, Braun N, Zimmermann H, Jain D, Knowles AF, Sévigny J. Ectonucleotidase NTPDase2 is selectively down-regulated in biliary cirrhosis. Journal Of Investigative Medicine : The Official Publication Of The American Federation For Clinical Research 2004, 52: 475-82. PMID: 15651265, DOI: 10.1136/jim-52-07-42.
- Kaplan DH, Anderson BE, McNiff JM, Jain D, Shlomchik MJ, Shlomchik WD. Target antigens determine graft-versus-host disease phenotype. Journal Of Immunology (Baltimore, Md. : 1950) 2004, 173: 5467-75. PMID: 15494494, DOI: 10.4049/jimmunol.173.9.5467.
- Hong-Curtis J, Yeh MM, Jain D, Lee JH. Rapid progression of autoimmune hepatitis in the background of primary sclerosing cholangitis. Journal Of Clinical Gastroenterology 2004, 38: 906-9. PMID: 15492611, DOI: 10.1097/00004836-200411000-00015.
- Gustavo LC, Robert ME, Lamps LW, Lagarde SP, Jain D. Isolated gastric malakoplakia: a case report and review of the literature. Archives Of Pathology & Laboratory Medicine 2004, 128: e153-6. PMID: 15504079, DOI: 10.5858/2004-128-e153-IGMACR.
- Matte CC, Liu J, Cormier J, Anderson BE, Athanasiadis I, Jain D, McNiff J, Shlomchik WD. Donor APCs are required for maximal GVHD but not for GVL. Nature Medicine 2004, 10: 987-92. PMID: 15286785, DOI: 10.1038/nm1089.
- Prasad P, Salem RR, Mangla R, Aslanian H, Jain D, Lee J. Lymphoplasmacytic sclerosing pancreato-cholangitis: a case report and review of the literature. The Yale Journal Of Biology And Medicine 2004, 77: 143-8. PMID: 15989743, PMCID: PMC2259126.
- Yeh MM, Tang LH, Wang S, Robert ME, Zheng W, Jain D. Inhibin expression in ovarian-type stroma in mucinous cystic neoplasms of the pancreas. Applied Immunohistochemistry & Molecular Morphology : AIMM / Official Publication Of The Society For Applied Immunohistochemistry 2004, 12: 148-52. PMID: 15354741, DOI: 10.1097/00129039-200406000-00009.
- Eslami-Varzaneh F, Washington K, Robert ME, Kashgarian M, Goldblum JR, Jain D. Benign fibroblastic polyps of the colon: a histologic, immunohistochemical, and ultrastructural study. The American Journal Of Surgical Pathology 2004, 28: 374-8. PMID: 15104300, DOI: 10.1097/00000478-200403000-00010.
- Marginean EC, Jain D. Alcoholic pancreatitis: is it a priori chronic disease? Journal Of Clinical Gastroenterology 2004, 38: 203-5. PMID: 15128063, DOI: 10.1097/00004836-200403000-00002.
- Mariappan MR, Fadare O, Jain D. Sebaceous differentiation in salivary glands. Archives Of Pathology & Laboratory Medicine 2004, 128: 245-6. PMID: 14736269, DOI: 10.5858/2004-128-245-SDISG.
- Jain D, Robert ME, Navarro V, Friedman AL, Crawford JM. Total fibrous obliteration of main portal vein and portal foam cell venopathy in chronic hepatic allograft rejection. Archives Of Pathology & Laboratory Medicine 2004, 128: 64-7. PMID: 14692809, DOI: 10.5858/2004-128-64-TFOOMP.
- Koullias GJ, Korkolis DP, Hatzaras IS, Elefteriades JA, Jain D. Immunohistochemical testing for Helicobacter pylori infection in ascending aortic aneurysms and penetrating aortic ulcers. The American Journal Of Cardiology 2004, 93: 122-3. PMID: 14697486, DOI: 10.1016/j.amjcard.2003.09.025.
- Jain D, Moussa K, Tandon M, Culpepper-Morgan J, Proctor DD. Role of interstitial cells of Cajal in motility disorders of the bowel. The American Journal Of Gastroenterology 2003, 98: 618-24. PMID: 12650797, DOI: 10.1111/j.1572-0241.2003.07295.x.
- Calhoun BC, Gomes F, Robert ME, Jain D. Sampling error in the standard evaluation of endoscopic colonic biopsies. The American Journal Of Surgical Pathology 2003, 27: 254-7. PMID: 12548174, DOI: 10.1097/00000478-200302000-00016.
- Jain D, Martel M, Reyes-Múgica M, Parkash V. Heterotopic nephrogenic rests in the colon and multiple congenital anomalies: possibly related association. Pediatric And Developmental Pathology : The Official Journal Of The Society For Pediatric Pathology And The Paediatric Pathology Society 2002, 5: 587-91. PMID: 12375130, DOI: 10.1007/s10024-002-0055-4.
- Jain D. Diagnosis of hepatocellular carcinoma: fine needle aspiration cytology or needle core biopsy. Journal Of Clinical Gastroenterology 2002, 35: S101-8. PMID: 12394213, DOI: 10.1097/00004836-200211002-00006.
- Kruglov EA, Jain D, Dranoff JA. Isolation of primary rat liver fibroblasts. Journal Of Investigative Medicine : The Official Publication Of The American Federation For Clinical Research 2002, 50: 179-84. PMID: 12033282, DOI: 10.2310/6650.2002.33431.
- Tang LH, Hui P, Garcia-Tsao G, Salem RR, Jain D. Multiple angiomyolipomata of the liver: a case report. Modern Pathology : An Official Journal Of The United States And Canadian Academy Of Pathology, Inc 2002, 15: 167-71. PMID: 11850546, DOI: 10.1038/modpathol.3880509.
- Robert ME, Singh SK, Ikuma M, Jain D, Ardito T, Binder HJ. Morphology of isolated colonic crypts. Cells, Tissues, Organs 2001, 168: 246-51. PMID: 11275691, DOI: 10.1159/000047841.
- Jain D, Bowlus CL, Anderson JM, Robert ME. Granular cells as a marker of early amiodarone hepatotoxicity. Journal Of Clinical Gastroenterology 2000, 31: 241-3. PMID: 11034006, DOI: 10.1097/00004836-200010000-00012.
- Garcia-Tsao G, Korzenik JR, Young L, Henderson KJ, Jain D, Byrd B, Pollak JS, White RI. Liver disease in patients with hereditary hemorrhagic telangiectasia. The New England Journal Of Medicine 2000, 343: 931-6. PMID: 11006369, DOI: 10.1056/NEJM200009283431305.
- Jain D, Sarode VR, Abdul-Karim FW, Homer R, Robert ME. Evidence for the neoplastic transformation of Von-Meyenburg complexes. The American Journal Of Surgical Pathology 2000, 24: 1131-9. PMID: 10935654, DOI: 10.1097/00000478-200008000-00011.
Biography
Dhanpat Jain, MD, is a pathologist specializing in gastrointestinal (GI) and liver diseases and cancers. Before he graduated high school, Dr. Jain knew he would pursue a career in medicine. Not until later in his medical training did he discover that he could apply his interests in visual art and pattern recognition to a field like pathology. “It is a natural fit for me,” Dr. Jain says.
On a daily basis, Dr. Jain examines tissue samples and biopsies from patients with suspected GI and liver diseases. He has extensive experience with samples that reflect motility, or movement, disorders of the GI tract. “These are uncommon disorders and not many people examine cases like this,” Dr. Jain says. For this reason, he regularly consults with physicians and other pathologists across the globe on challenging cases.
As a professor of pathology and of medicine (digestive diseases) at Yale School of Medicine, Dr. Jain researches liver tumors, inflammatory bowel disease, and cancers related to the liver and digestive tract.
Titles
- Professor of Pathology and of Medicine (Digestive Diseases)
Education & Training
- ResidentYale University School of Medicine (1999)
- ResidentYale University School of Medicine (1998)
- FellowYale University School of Medicine (1996)
- Senior ResidentPost Graduate Institute of Medical Education and Research (1994)
- ResidentPost Graduate Institute of Medical Education and Research (1991)
- MDPost Graduate Institute of Medical Education and Research, Chandigarh, India, Pathology (1989)
- MDMysore Medical College (1986)
Languages Spoken
- বাংলা (Bengali)
- English
- हिन्दी (Hindi)
Additional Information
Honors & Recognitions
- Averill A. Liebow Award: Department of Pathology (2014)
- Billing Compliance leader of the year: YMG (2005)
- Howard Spiro Award: Section of Digestive Diseases (2003)
- Averill A. Liebow Award: Department of Pathology (2000)
Board Certifications
- AB of Pathology, Anatomic Pathology (1998)
Professional Service
- College of American Pathologists (2022 - 2023): Committee Member
Publications
- Lam R, Tarangelo N, Wang R, Horibe M, Grimshaw AA, Jain D, Haffar S, Bazerbachi F, Kunz PL, Li DK. Microangiopathic Hemolytic Anemia Is a Late and Fatal Complication of Gastric Signet Ring Cell Carcinoma: A Systematic Review and Case-Control Study. The Oncologist 2022, 27: 751-759. PMID: 35589098, PMCID: PMC9438916, DOI: 10.1093/oncolo/oyac093.
- Madoff DC, Abi-Jaoudeh N, Braxton D, Goyal L, Jain D, Odisio BC, Salem R, Schattner M, Sheth R, Li D. An Expert, Multidisciplinary Perspective on Best Practices in Biomarker Testing in Intrahepatic Cholangiocarcinoma. The Oncologist 2022 PMID: 35925597, DOI: 10.1093/oncolo/oyac139.
- Mirza H, Besse W, Somlo S, Weinreb J, Kenney B, Jain D. An Update on Ductal Plate Malformations and Fibropolycystic Diseases of the Liver. Human Pathology 2022 PMID: 35777701, DOI: 10.1016/j.humpath.2022.06.022.
- Zhang X, Jain D. The many faces and pathologic diagnostic challenges of autoimmune hepatitis. Human Pathology 2022 PMID: 35753409, DOI: 10.1016/j.humpath.2022.06.019.
- Wang D, González IA, Russo PA, Jain D, Zhang X. Prominent Pseudoacini in Focal Nodular Hyperplasia: A Potential Diagnostic Pitfall. The American Journal Of Surgical Pathology 2022 PMID: 35749760, DOI: 10.1097/PAS.0000000000001931.
- Lerch JM, Pai RK, Brown I, Gill AJ, Jain D, Kővári B, Kushima R, Sheahan K, Slavik T, Srivastava A, Lauwers GY, Langner C. Interobserver agreement of estimating the extent of intestinal metaplasia in patients with chronic atrophic gastritis. Virchows Archiv : An International Journal Of Pathology 2022, 480: 1277-1281. PMID: 34904185, PMCID: PMC9184363, DOI: 10.1007/s00428-021-03245-9.
- Yasir S, Chen ZE, Jain D, Kakar S, Wu TT, Yeh MM, Torbenson MS. Hepatic Adenomas in Patients 60 and Older Are Enriched for HNF1A Inactivation and Malignant Transformation. The American Journal Of Surgical Pathology 2022, 46: 786-792. PMID: 35383587, DOI: 10.1097/PAS.0000000000001892.
- Wang JD, Sebastian C, Walther Z, Suresh T, Lacy J, Zhang X, Jain D. An Appraisal of Immunohistochemical Stain Use in Hepatic Metastasis Highlights the Effectiveness of the Individualized, Case-Based Approach. Archives Of Pathology & Laboratory Medicine 2022 PMID: 35512224, DOI: 10.5858/arpa.2021-0457-OA.
- Lohse AW, Sebode M, Bhathal PS, Clouston AD, Dienes HP, Jain D, Gouw ASH, Guindi M, Kakar S, Kleiner DE, Krech T, Lackner C, Longerich T, Saxena R, Terracciano L, Washington K, Weidemann S, Hübscher SG, Tiniakos D. Consensus recommendations for histological criteria of autoimmune hepatitis from the International AIH Pathology Group: Results of a workshop on AIH histology hosted by the European Reference Network on Hepatological Diseases and the European Society of Pathology: Results of a workshop on AIH histology hosted by the European Reference Network on Hepatological Diseases and the European Society of Pathology. Liver International : Official Journal Of The International Association For The Study Of The Liver 2022, 42: 1058-1069. PMID: 35230735, DOI: 10.1111/liv.15217.
- Lerch JM, Pai RK, Brown I, Gill AJ, Jain D, Kővári B, Kushima R, Sheahan K, Slavik T, Srivastava A, Lauwers GY, Langner C. Subtyping intestinal metaplasia in patients with chronic atrophic gastritis: an interobserver variability study. Pathology 2022, 54: 262-268. PMID: 35221041, DOI: 10.1016/j.pathol.2021.12.288.
- Bhat N, Esteghamat F, Chaube BK, Gunawardhana K, Mani M, Thames C, Jain D, Ginsberg HN, Fernandes-Hernando C, Mani A. TCF7L2 transcriptionally regulates Fgf15 to maintain bile acid and lipid homeostasis through gut-liver crosstalk. FASEB Journal : Official Publication Of The Federation Of American Societies For Experimental Biology 2022, 36: e22185. PMID: 35133032, DOI: 10.1096/fj.202101607R.
- Jain A, Mazer B, Deng Y, Ciarleglio M, Jain D, Taddei T, Zhang X. Hepatocellular Carcinoma: Does the Background Liver With or Without Cirrhosis Matter? American Journal Of Clinical Pathology 2022, 157: 305-313. PMID: 34542582, DOI: 10.1093/ajcp/aqab125.
- Li H, Zhang X, Finberg KE, Walther Z, Jain D, Gibson J. Pathogenic BRCA2 germline variants in combined hepatocellular-cholangiocarcinoma. Pathology International 2022, 72: 138-140. PMID: 34808016, DOI: 10.1111/pin.13188.
- Bhat N, Narayanan A, Fathzadeh M, Kahn M, Zhang D, Goedeke L, Neogi A, Cardone RL, Kibbey RG, Fernandez-Hernando C, Ginsberg HN, Jain D, Shulman G, Mani A. Dyrk1b promotes hepatic lipogenesis by bypassing canonical insulin signaling and directly activating mTORC2 in mice. The Journal Of Clinical Investigation 2022, 132 PMID: 34855620, PMCID: PMC8803348, DOI: 10.1172/JCI153724.
- Ugwu N, Atzmony L, Ellis KT, Panse G, Jain D, Ko CJ, Nassiri N, Choate KA. Erratum: Cutaneous and hepatic vascular lesions due to a recurrent somatic GJA4 mutation reveal a pathway for vascular malformation. HGG Advances 2022, 3: 100061. PMID: 35047851, PMCID: PMC8756555, DOI: 10.1016/j.xhgg.2021.100061.
- Patil PA, Taddei T, Jain D, Zhang X. HNF-1β is a More Sensitive and Specific Marker Than C-Reactive Protein for Identifying Biliary Differentiation in Primary Hepatic Carcinomas. Archives Of Pathology & Laboratory Medicine 2022, 146: 220-226. PMID: 34086854, DOI: 10.5858/arpa.2020-0725-OA.
- Pacheco MC, Torbenson MS, Wu TT, Kakar S, Jain D, Yeh MM. Pediatric Hepatocellular Adenomas: The Influence of Age and Syndrome on Subtype. The American Journal Of Surgical Pathology 2021, 45: 1641-1647. PMID: 34148984, PMCID: PMC8608351, DOI: 10.1097/PAS.0000000000001763.
- Jain D, Sreenivasan P, Inayat I, Deng Y, Ciarleglio MM, Garcia-Tsao G. Thick Fibrous Septa on Liver Biopsy Specimens Predict the Development of Decompensation in Patients With Compensated Cirrhosis. American Journal Of Clinical Pathology 2021, 156: 802-809. PMID: 33940622, PMCID: PMC8512277, DOI: 10.1093/ajcp/aqab024.
- Wen KW, Joseph NM, Srivastava A, Saunders TA, Jain D, Rank J, Feely M, Zarrinpar A, Al Diffalha S, Shyn PB, Graham RP, Drage MG, Kakar S. Inhibin-positive hepatic carcinoma: proposal for a solid-tubulocystic variant of intrahepatic cholangiocarcinoma. Human Pathology 2021, 116: 82-93. PMID: 34298064, DOI: 10.1016/j.humpath.2021.07.004.
- Yan K, Hung A, Parmer C, Yang H, Jain D, Lim B, Goodman AL, Garcia-Tsao G. Obeticholic Acid Decreases Intestinal Content of Enterococcus in Rats With Cirrhosis and Ascites. Hepatology Communications 2021, 5: 1507-1517. PMID: 34510838, PMCID: PMC8435275, DOI: 10.1002/hep4.1740.
- Rottmann BG, Patel N, Ahmed M, Deng Y, Ciarleglio M, Vyas M, Jain D, Zhang X. Clinicopathological significance of neutrophil-rich colorectal carcinoma. Journal Of Clinical Pathology 2021 PMID: 34312298, DOI: 10.1136/jclinpath-2021-207702.
- Drzewiecki K, Choi J, Brancale J, Leney-Greene MA, Sari S, Dalgiç B, Ünlüsoy Aksu A, Evirgen Şahin G, Ozen A, Baris S, Karakoc-Aydiner E, Jain D, Kleiner D, Schmalz M, Radhakrishnan K, Zhang J, Hoebe K, Su HC, Pereira JP, Lenardo MJ, Lifton RP, Vilarinho S. GIMAP5 maintains liver endothelial cell homeostasis and prevents portal hypertension. The Journal Of Experimental Medicine 2021, 218 PMID: 33956074, PMCID: PMC8105721, DOI: 10.1084/jem.20201745.
- Kumar D, Hafez O, Jain D, Zhang X. Can primary hepatocellular carcinoma histomorphology predict extrahepatic metastasis? Human Pathology 2021, 113: 39-46. PMID: 33905775, DOI: 10.1016/j.humpath.2021.04.008.
- Lu SX, Huang YH, Liu LL, Zhang CZ, Yang X, Yang YZ, Shao CK, Li JM, Xie D, Zhang X, Jain D, Yun JP. α-Fetoprotein mRNA in situ hybridisation is a highly specific marker of hepatocellular carcinoma: a multi-centre study. British Journal Of Cancer 2021, 124: 1988-1996. PMID: 33824478, PMCID: PMC8184895, DOI: 10.1038/s41416-021-01363-4.
- Vyas M, Jain D. An update on subtypes of hepatocellular carcinoma: From morphology to molecular. Indian Journal Of Pathology & Microbiology 2021, 64: S112-S120. PMID: 34135152, DOI: 10.4103/IJPM.IJPM_751_20.
- Ugwu N, Atzmony L, Ellis KT, Panse G, Jain D, Ko CJ, Nassiri N, Choate KA. Cutaneous and hepatic vascular lesions due to a recurrent somatic GJA4 mutation reveal a pathway for vascular malformation. HGG Advances 2021, 2 PMID: 33912852, PMCID: PMC8078848, DOI: 10.1016/j.xhgg.2021.100028.
- Celli R, Saffo S, Kamili S, Wiese N, Hayden T, Taddei T, Jain D. Liver Pathologic Changes After Direct-Acting Antiviral Agent Therapy and Sustained Virologic Response in the Setting of Chronic Hepatitis C Virus Infection. Archives Of Pathology & Laboratory Medicine 2021, 145: 419-427. PMID: 32810870, DOI: 10.5858/arpa.2020-0008-OA.
- Cheng L, Jain D, Kakar S, Torbenson MS, Wu TT, Yeh MM. Hepatocellular neoplasms arising in genetic metabolic disorders: steatosis is common in both the tumor and background liver. Human Pathology 2021, 108: 93-99. PMID: 33245984, DOI: 10.1016/j.humpath.2020.11.012.
- Tefera J, Revzin M, Chapiro J, Savic L, Mulligan D, Batra R, Taddei T, Jain D, Zhang X. Fibronodular hepatocellular carcinoma-a new variant of liver cancer: clinical, pathological and radiological correlation. Journal Of Clinical Pathology 2021, 74: 31-35. PMID: 32430483, PMCID: PMC7674234, DOI: 10.1136/jclinpath-2020-206574.
- Jain D, Torres R, Celli R, Koelmel J, Charkoftaki G, Vasiliou V. Evolution of the liver biopsy and its future. Translational Gastroenterology And Hepatology 2021, 6: 20. PMID: 33824924, PMCID: PMC7829074, DOI: 10.21037/tgh.2020.04.01.
- Zhang X, Jain D. Updates in staging and pathologic evaluation of esophageal carcinoma following neoadjuvant therapy. Annals Of The New York Academy Of Sciences 2020, 1482: 163-176. PMID: 32892349, DOI: 10.1111/nyas.14462.
- Vyas M, Celli R, Singh M, Patel N, Aslanian HR, Boffa D, Deng Y, Ciarleglio MM, Laine L, Jain D. Intestinal metaplasia around the gastroesophageal junction is frequently associated with antral reactive gastropathy: implications for carcinoma at the gastroesophageal junction. Human Pathology 2020, 105: 67-73. PMID: 32941964, DOI: 10.1016/j.humpath.2020.08.007.
- Odio CD, O'Brien CR, Jacox J, Jain D, Lee AI. Cryptic Cachexia. The New England Journal Of Medicine 2020, 383: 68-74. PMID: 32609985, DOI: 10.1056/NEJMcps1817531.
- Gao E, Cheema H, Waheed N, Mushtaq I, Erden N, Nelson-Williams C, Jain D, Soroka CJ, Boyer JL, Khalil Y, Clayton PT, Mistry PK, Lifton RP, Vilarinho S. Organic Solute Transporter Alpha Deficiency: A Disorder With Cholestasis, Liver Fibrosis, and Congenital Diarrhea. Hepatology (Baltimore, Md.) 2020, 71: 1879-1882. PMID: 31863603, PMCID: PMC8577800, DOI: 10.1002/hep.31087.
- Roulis M, Kaklamanos A, Schernthanner M, Bielecki P, Zhao J, Kaffe E, Frommelt LS, Qu R, Knapp MS, Henriques A, Chalkidi N, Koliaraki V, Jiao J, Brewer JR, Bacher M, Blackburn HN, Zhao X, Breyer RM, Aidinis V, Jain D, Su B, Herschman HR, Kluger Y, Kollias G, Flavell RA. Paracrine orchestration of intestinal tumorigenesis by a mesenchymal niche. Nature 2020, 580: 524-529. PMID: 32322056, PMCID: PMC7490650, DOI: 10.1038/s41586-020-2166-3.
- Johncilla M, Grover S, Zhang X, Jain D, Srivastava A. Morphological spectrum of immune check-point inhibitor therapy-associated gastritis. Histopathology 2020, 76: 531-539. PMID: 31692018, DOI: 10.1111/his.14029.
- Ueasilamongkol P, Khamphaya T, Guerra MT, Rodrigues M, Gomes DA, Kong Y, Wei W, Jain D, Trampert DC, Ananthanarayanan M, Banales JM, Roberts LR, Farshidfar F, Nathanson MH, Weerachayaphorn J. Type 3 Inositol 1,4,5-Trisphosphate Receptor Is Increased and Enhances Malignant Properties in Cholangiocarcinoma. Hepatology (Baltimore, Md.) 2020, 71: 583-599. PMID: 31251815, PMCID: PMC6934938, DOI: 10.1002/hep.30839.
- Patel N, Vyas M, Celli R, Jain D, Zhang X. Adverse Histologic Features in Colorectal Nonpedunculated Malignant Polyps With Nodal Metastasis. The American Journal Of Surgical Pathology 2020, 44: 241-246. PMID: 31498179, DOI: 10.1097/PAS.0000000000001369.
- Olave MC, Gurung A, Mistry PK, Kakar S, Yeh M, Xu M, Wu TT, Torbenson M, Jain D. Etiology of cirrhosis in the young. Human Pathology 2020, 96: 96-103. PMID: 31698008, DOI: 10.1016/j.humpath.2019.09.015.
- Guo Y, Jain D, Weinreb J. Von Meyenburg Complex: Current Concepts and Imaging Misconceptions. Journal Of Computer Assisted Tomography 2019, 43: 846-851. PMID: 31356525, DOI: 10.1097/RCT.0000000000000904.
- Nalbantoglu I, Jain D. Cryptogenic cirrhosis: Old and new perspectives in the era of molecular and genomic medicine. Seminars In Diagnostic Pathology 2019, 36: 389-394. PMID: 31395291, DOI: 10.1053/j.semdp.2019.07.003.
- Pai RK, Kleiner DE, Hart J, Adeyi OA, Clouston AD, Behling CA, Jain D, Kakar S, Brahmania M, Burgart L, Batts KP, Valasek MA, Torbenson MS, Guindi M, Wang HL, Ajmera V, Adams LA, Parker CE, Feagan BG, Loomba R, Jairath V. Standardising the interpretation of liver biopsies in non-alcoholic fatty liver disease clinical trials. Alimentary Pharmacology & Therapeutics 2019, 50: 1100-1111. PMID: 31583739, PMCID: PMC6817398, DOI: 10.1111/apt.15503.
- Balitzer D, Joseph NM, Ferrell L, Shafizadeh N, Jain D, Zhang X, Yeh M, di Tommaso L, Kakar S. Immunohistochemical and molecular features of cholangiolocellular carcinoma are similar to well-differentiated intrahepatic cholangiocarcinoma. Modern Pathology : An Official Journal Of The United States And Canadian Academy Of Pathology, Inc 2019, 32: 1486-1494. PMID: 31186529, DOI: 10.1038/s41379-019-0290-0.
- Beech C, Freedman-Weiss M, Salem R, Jain D, Zhang X. Pancreatic Intraductal Papillary Mucinous Neoplasm With Elevated Pre-Operative Cystic Carcinoembryonic Antigen Level: A Histopathologic Correlation. Gastroenterology Research 2019, 12: 185-190. PMID: 31523327, PMCID: PMC6731045, DOI: 10.14740/gr1201.
- Morin-Zorman S, Wysocki C, Zhu J, Li H, Zorman S, Matte-Martone C, Kisanga E, McNiff J, Jain D, Gonzalez D, Rothstein DM, Lakkis FG, Haberman A, Shlomchik WD. In vivo dynamics of T cells and their interactions with dendritic cells in mouse cutaneous graft-versus-host disease. Blood Advances 2019, 3: 2082-2092. PMID: 31296496, PMCID: PMC6650737, DOI: 10.1182/bloodadvances.2019000227.
- Arnold CA, Graham RP, Jain D, Kakar S, Lam-Himlin DM, Naini BV, Wu TT, Yeh MM, Torbenson MS. Knowledge gaps in the appendix: a multi-institutional study from seven academic centers. Modern Pathology : An Official Journal Of The United States And Canadian Academy Of Pathology, Inc 2019, 32: 988-996. PMID: 30765881, DOI: 10.1038/s41379-019-0216-x.
- Jeon Y, Benedict M, Taddei T, Jain D, Zhang X. Macrotrabecular Hepatocellular Carcinoma: An Aggressive Subtype of Hepatocellular Carcinoma. The American Journal Of Surgical Pathology 2019, 43: 943-948. PMID: 31135484, DOI: 10.1097/PAS.0000000000001289.
- Hakim A, Zhang X, DeLisle A, Oral EA, Dykas D, Drzewiecki K, Assis DN, Silveira M, Batisti J, Jain D, Bale A, Mistry PK, Vilarinho S. Clinical utility of genomic analysis in adults with idiopathic liver disease. Journal Of Hepatology 2019, 70: 1214-1221. PMID: 31000363, PMCID: PMC6526061, DOI: 10.1016/j.jhep.2019.01.036.
- Vyas M, Patel N, Celli R, Wajapeyee N, Jain D, Zhang X. Glucose Metabolic Reprogramming and Cell Proliferation Arrest in Colorectal Micropapillary Carcinoma. Gastroenterology Research 2019, 12: 128-134. PMID: 31236153, PMCID: PMC6575135, DOI: 10.14740/gr1145.
- Torbenson MS, Arnold CA, Graham RP, Jain D, Kakar S, Lam-Himlin DM, Naini BV, Wu TT, Yeh M. Identification of key challenges in liver pathology: data from a multicenter study of extramural consults. Human Pathology 2019, 87: 75-82. PMID: 30857968, DOI: 10.1016/j.humpath.2019.03.001.
- Ünlüsoy Aksu A, Das SK, Nelson-Williams C, Jain D, Özbay Hoşnut F, Evirgen Şahin G, Lifton RP, Vilarinho S. Recessive Mutations in KIF12 Cause High Gamma-Glutamyltransferase Cholestasis. Hepatology Communications 2019, 3: 471-477. PMID: 30976738, PMCID: PMC6442693, DOI: 10.1002/hep4.1320.
- Codina A, Renauer PA, Wang G, Chow RD, Park JJ, Ye H, Zhang K, Dong MB, Gassaway B, Ye L, Errami Y, Shen L, Chang A, Jain D, Herbst RS, Bosenberg M, Rinehart J, Fan R, Chen S. Convergent Identification and Interrogation of Tumor-Intrinsic Factors that Modulate Cancer Immunity In Vivo. Cell Systems 2019, 8: 136-151.e7. PMID: 30797773, PMCID: PMC6592847, DOI: 10.1016/j.cels.2019.01.004.
- Celli R, Tang LH, Cai G, Freedman-Weiss M, Colunga M, Salem RR, Majumdar S, Jain D. Proinsulin Expressing Neuroendocrine Tumors of the Pancreas: An Underrecognized Entity. Pancreas 2019, 48: 55-59. PMID: 30451800, DOI: 10.1097/MPA.0000000000001196.
- Gurung A, Assis DN, McCarty TR, Mitchell KA, Boyer JL, Jain D. Histologic features of autoimmune hepatitis: a critical appraisal. Human Pathology 2018, 82: 51-60. PMID: 30041025, DOI: 10.1016/j.humpath.2018.07.014.
- Sari S, Dalgic B, Muehlenbachs A, DeLeon-Carnes M, Goldsmith CS, Ekinci O, Jain D, Keating MK, Vilarinho S. Prototheca zopfii Colitis in Inherited CARD9 Deficiency. The Journal Of Infectious Diseases 2018, 218: 485-489. PMID: 29659908, PMCID: PMC6049027, DOI: 10.1093/infdis/jiy198.
- Benedict MA, Lauwers GY, Jain D. Gastric Adenocarcinoma of the Fundic Gland Type: Update and Literature Review. American Journal Of Clinical Pathology 2018, 149: 461-473. PMID: 29648578, DOI: 10.1093/ajcp/aqy019.
- Manfredo Vieira S, Hiltensperger M, Kumar V, Zegarra-Ruiz D, Dehner C, Khan N, Costa FRC, Tiniakou E, Greiling T, Ruff W, Barbieri A, Kriegel C, Mehta SS, Knight JR, Jain D, Goodman AL, Kriegel MA. Translocation of a gut pathobiont drives autoimmunity in mice and humans. Science (New York, N.Y.) 2018, 359: 1156-1161. PMID: 29590047, PMCID: PMC5959731, DOI: 10.1126/science.aar7201.
- Vyas M, Jain D. A practical diagnostic approach to hepatic masses. Indian Journal Of Pathology & Microbiology 2018, 61: 2-17. PMID: 29567877, DOI: 10.4103/IJPM.IJPM_578_17.
- Graham RP, Yeh MM, Lam-Himlin D, Roberts LR, Terracciano L, Cruise MW, Greipp PT, Zreik RT, Jain D, Zaid N, Salaria SN, Jin L, Wang X, Rustin JG, Kerr SE, Sukov WR, Solomon DA, Kakar S, Waterhouse E, Gill RM, Ferrell L, Alves VA, Nart D, Yilmaz F, Roessler S, Longerich T, Schirmacher P, Torbenson MS. Molecular testing for the clinical diagnosis of fibrolamellar carcinoma. Modern Pathology : An Official Journal Of The United States And Canadian Academy Of Pathology, Inc 2018, 31: 141-149. PMID: 28862261, PMCID: PMC5758901, DOI: 10.1038/modpathol.2017.103.
- Zhang X, Zhu H, Yang X, Adsay VN, Jain D. Post-obstructive cyst formation in pancreas and cystic acinar transformation: Are they same? Pathology, Research And Practice 2017, 213: 997-1001. PMID: 28599853, DOI: 10.1016/j.prp.2017.03.013.
- Murtha TD, Lupsa BC, Majumdar S, Jain D, Salem RR. A Systematic Review of Proinsulin-Secreting Pancreatic Neuroendocrine Tumors. Journal Of Gastrointestinal Surgery : Official Journal Of The Society For Surgery Of The Alimentary Tract 2017, 21: 1335-1341. PMID: 28510792, DOI: 10.1007/s11605-017-3428-8.
- Lawless ME, Toweill DL, Jewell KD, Jain D, Lamps L, Krasinskas AM, Swanson PE, Upton MP, Yeh MM. Massive Gastric Juvenile Polyposis: A Clinicopathologic Study Using SMAD4 Immunohistochemistry. American Journal Of Clinical Pathology 2017, 147: 390. PMID: 28340255, DOI: 10.1093/ajcp/aqx015.
- Cai SY, Ouyang X, Chen Y, Soroka CJ, Wang J, Mennone A, Wang Y, Mehal WZ, Jain D, Boyer JL. Bile acids initiate cholestatic liver injury by triggering a hepatocyte-specific inflammatory response. JCI Insight 2017, 2: e90780. PMID: 28289714, PMCID: PMC5333973, DOI: 10.1172/jci.insight.90780.
- Bartley AN, Washington MK, Colasacco C, Ventura CB, Ismaila N, Benson AB, Carrato A, Gulley ML, Jain D, Kakar S, Mackay HJ, Streutker C, Tang L, Troxell M, Ajani JA. HER2 Testing and Clinical Decision Making in Gastroesophageal Adenocarcinoma: Guideline From the College of American Pathologists, American Society for Clinical Pathology, and the American Society of Clinical Oncology. Journal Of Clinical Oncology : Official Journal Of The American Society Of Clinical Oncology 2017, 35: 446-464. PMID: 28129524, DOI: 10.1200/JCO.2016.69.4836.
- Bartley AN, Washington MK, Ventura CB, Ismaila N, Colasacco C, Benson AB, Carrato A, Gulley ML, Jain D, Kakar S, Mackay HJ, Streutker C, Tang L, Troxell M, Ajani JA. HER2 Testing and Clinical Decision Making in Gastroesophageal Adenocarcinoma: Guideline From the College of American Pathologists, American Society for Clinical Pathology, and American Society of Clinical Oncology. Archives Of Pathology & Laboratory Medicine 2016, 140: 1345-1363. PMID: 27841667, DOI: 10.5858/arpa.2016-0331-CP.
- Celli R, Colunga M, Patel N, Djekidel M, Jain D. Metabolic Signature on 18F-FDG PET/CT, HER2 Status, and Survival in Gastric Adenocarcinomas. Journal Of Nuclear Medicine Technology 2016, 44: 234-238. PMID: 27789750, DOI: 10.2967/jnmt.116.181479.
- Bartley AN, Washington MK, Ventura CB, Ismaila N, Colasacco C, Benson AB, Carrato A, Gulley ML, Jain D, Kakar S, Mackay HJ, Streutker C, Tang L, Troxell M, Ajani JA. HER2 Testing and Clinical Decision Making in Gastroesophageal Adenocarcinoma: Guideline From the College of American Pathologists, American Society for Clinical Pathology, and American Society of Clinical Oncology. American Journal Of Clinical Pathology 2016, 146: 647-669. PMID: 28077399, PMCID: PMC6272805, DOI: 10.1093/ajcp/aqw206.
- Vilarinho S, Sari S, Mazzacuva F, Bilgüvar K, Esendagli-Yilmaz G, Jain D, Akyol G, Dalgiç B, Günel M, Clayton PT, Lifton RP. ACOX2 deficiency: A disorder of bile acid synthesis with transaminase elevation, liver fibrosis, ataxia, and cognitive impairment. Proceedings Of The National Academy Of Sciences Of The United States Of America 2016, 113: 11289-11293. PMID: 27647924, PMCID: PMC5056113, DOI: 10.1073/pnas.1613228113.
- Binder HJ, Jain D. Does Increased Duodenal Intraepithelial Lymphocytosis Always Equate With Marsh 1 Lesion? Journal Of Clinical Gastroenterology 2016, 50: 613-4. PMID: 27509445, DOI: 10.1097/MCG.0000000000000562.
- Lu H, Wang T, Li J, Fedele C, Liu Q, Zhang J, Jiang Z, Jain D, Iozzo RV, Violette SM, Weinreb PH, Davis RJ, Gioeli D, FitzGerald TJ, Altieri DC, Languino LR. αvβ6 Integrin Promotes Castrate-Resistant Prostate Cancer through JNK1-Mediated Activation of Androgen Receptor. Cancer Research 2016, 76: 5163-74. PMID: 27450452, PMCID: PMC5012867, DOI: 10.1158/0008-5472.CAN-16-0543.
- Bernardo RM, Gurung A, Jain D, Malinis MF. Therapeutic Challenges of Hepatic Mucormycosis in Hematologic Malignancy: A Case Report and Review of the Literature. The American Journal Of Case Reports 2016, 17: 484-9. PMID: 27406045, PMCID: PMC4948661, DOI: 10.12659/ajcr.898480.
- Vilarinho S, Sari S, Yilmaz G, Stiegler AL, Boggon TJ, Jain D, Akyol G, Dalgic B, Günel M, Lifton RP. Recurrent recessive mutation in deoxyguanosine kinase causes idiopathic noncirrhotic portal hypertension. Hepatology (Baltimore, Md.) 2016, 63: 1977-86. PMID: 26874653, PMCID: PMC4874872, DOI: 10.1002/hep.28499.
- Host factors are dominant in the development of post-liver transplant non-alcoholic steatohepatitis.Boga S, Munoz-Abraham AS, Rodriguez-Davalos MI, Emre SH, Jain D, Schilsky ML. Host factors are dominant in the development of post-liver transplant non-alcoholic steatohepatitis. World Journal Of Hepatology 2016, 8: 659-64. PMID: 27239259, PMCID: PMC4876289, DOI: 10.4254/wjh.v8.i15.659.
- Monestime G, Borger DK, Kim J, Lopez G, Allgaeuer M, Jain D, Vortmeyer A, Wang HW, Sidransky E. Varied autopsy findings in five treated patients with Gaucher disease and parkinsonism include the absence of Gaucher cells. Molecular Genetics And Metabolism 2016, 118: 55-9. PMID: 26992326, DOI: 10.1016/j.ymgme.2016.02.008.
- Zhang Z, Jain D, Brand M. Ringed Esophagus Secondary to Lymphocytic Esophagitis. Gastroenterology & Hepatology 2016, 12: 237-9. PMID: 27231454, PMCID: PMC4872853.
- Vyas M, Zhang X, Morrow JS, Jain D, Salem RR, West AB. Focal hepatic glycogenosis associated with metastatic insulinoma presenting as mass lesions. Pathology, Research And Practice 2016, 212: 59-62. PMID: 26627264, DOI: 10.1016/j.prp.2015.11.006.
- Valika AK, Jain D, Jaffe PE, Moeckel G, Brewster UC. A Nodular Foreign Body Reaction in a Dialysis Patient Receiving Long-term Treatment With Lanthanum Carbonate. American Journal Of Kidney Diseases : The Official Journal Of The National Kidney Foundation 2016, 67: 128-32. PMID: 26385816, DOI: 10.1053/j.ajkd.2015.07.033.
- Boga S, Jain D, Schilsky ML. Trientine induced colitis during therapy for Wilson disease: a case report and review of the literature. BMC Pharmacology & Toxicology 2015, 16: 30. PMID: 26589720, PMCID: PMC4654910, DOI: 10.1186/s40360-015-0031-z.
- Boga S, Jain D, Schilsky ML. Presentation of Progressive Familial Intrahepatic Cholestasis Type 3 Mimicking Wilson Disease: Molecular Genetic Diagnosis and Response to Treatment. Pediatric Gastroenterology, Hepatology & Nutrition 2015, 18: 202-8. PMID: 26473142, PMCID: PMC4600706, DOI: 10.5223/pghn.2015.18.3.202.
- Nguyen T, Phillips D, Jain D, Torbenson M, Wu TT, Yeh MM, Kakar S. Comparison of 5 Immunohistochemical Markers of Hepatocellular Differentiation for the Diagnosis of Hepatocellular Carcinoma. Archives Of Pathology & Laboratory Medicine 2015, 139: 1028-34. PMID: 26230595, DOI: 10.5858/arpa.2014-0479-OA.
- Balakrishnan M, Garcia-Tsao G, Deng Y, Ciarleglio M, Jain D. Hepatic arteriolosclerosis: a small-vessel complication of diabetes and hypertension. The American Journal Of Surgical Pathology 2015, 39: 1000-9. PMID: 25786083, PMCID: PMC4466001, DOI: 10.1097/PAS.0000000000000419.
- Tuktamyshov R, Jain D, Ginsburg PM. Recurrence of Merkel cell carcinoma in the gastrointestinal tract: a case report. BMC Research Notes 2015, 8: 188. PMID: 25947008, PMCID: PMC4430924, DOI: 10.1186/s13104-015-1139-3.
- Sethi A, Jain D, Roland BC, Kinzel J, Gibson J, Schrader R, Hanson JA. Performing colonic mast cell counts in patients with chronic diarrhea of unknown etiology has limited diagnostic use. Archives Of Pathology & Laboratory Medicine 2015, 139: 225-32. PMID: 25611105, DOI: 10.5858/arpa.2013-0594-OA.
- Kakar S, Torbenson M, Jain D, Wu TT, Yeh M, Ferrell LD. Immunohistochemical pitfalls in the diagnosis of hepatocellular adenomas and focal nodular hyperplasia: accurate understanding of diverse staining patterns is essential for diagnosis and risk assessment. Modern Pathology : An Official Journal Of The United States And Canadian Academy Of Pathology, Inc 2015, 28: 159-60. PMID: 25560413, DOI: 10.1038/modpathol.2014.121.
- Vilarinho S, Choi M, Jain D, Malhotra A, Kulkarni S, Pashankar D, Phatak U, Patel M, Bale A, Mane S, Lifton RP, Mistry PK. Individual exome analysis in diagnosis and management of paediatric liver failure of indeterminate aetiology. Journal Of Hepatology 2014, 61: 1056-63. PMID: 25016221, PMCID: PMC4203706, DOI: 10.1016/j.jhep.2014.06.038.
- Mistry PK, Liu J, Sun L, Chuang WL, Yuen T, Yang R, Lu P, Zhang K, Li J, Keutzer J, Stachnik A, Mennone A, Boyer JL, Jain D, Brady RO, New MI, Zaidi M. Glucocerebrosidase 2 gene deletion rescues type 1 Gaucher disease. Proceedings Of The National Academy Of Sciences Of The United States Of America 2014, 111: 4934-9. PMID: 24639522, PMCID: PMC3977292, DOI: 10.1073/pnas.1400768111.
- Chen J, Wong S, Nathanson MH, Jain D. Evaluation of Barrett esophagus by multiphoton microscopy. Archives Of Pathology & Laboratory Medicine 2014, 138: 204-12. PMID: 24476518, PMCID: PMC4089503, DOI: 10.5858/arpa.2012-0675-OA.
- Joseph NM, Ferrell LD, Jain D, Torbenson MS, Wu TT, Yeh MM, Kakar S. Diagnostic utility and limitations of glutamine synthetase and serum amyloid-associated protein immunohistochemistry in the distinction of focal nodular hyperplasia and inflammatory hepatocellular adenoma. Modern Pathology : An Official Journal Of The United States And Canadian Academy Of Pathology, Inc 2014, 27: 62-72. PMID: 23807780, DOI: 10.1038/modpathol.2013.114.
- Gunal A, Hui P, Kilic S, Xu R, Jain D, Mitchell K, Robert M, Kenney B. KRAS mutations are associated with specific morphologic features in colon cancer. Journal Of Clinical Gastroenterology 2013, 47: 509-14. PMID: 23090042, DOI: 10.1097/MCG.0b013e3182703030.
- Krings G, Ramachandran R, Jain D, Wu TT, Yeh MM, Torbenson M, Kakar S. Immunohistochemical pitfalls and the importance of glypican 3 and arginase in the diagnosis of scirrhous hepatocellular carcinoma. Modern Pathology : An Official Journal Of The United States And Canadian Academy Of Pathology, Inc 2013, 26: 782-91. PMID: 23348905, DOI: 10.1038/modpathol.2012.243.
- Bedossa P, Garcia-Tsao G, Jain D. Cirrhosis Regression and Subclassification. Surgical Pathology Clinics 2013, 6: 295-309. PMID: 26838976, DOI: 10.1016/j.path.2013.03.006.
- Kakar S, Jain D. Liver Pathology: Unraveling the Art of Pattern Recognition. Surgical Pathology Clinics 2013, 6: ix-x. PMID: 26838980, DOI: 10.1016/j.path.2013.03.009.
- Marginean EC, Gown AM, Jain D. Diagnostic Approach to Hepatic Mass Lesions and Role of Immunohistochemistry. Surgical Pathology Clinics 2013, 6: 333-65. PMID: 26838978, DOI: 10.1016/j.path.2013.03.005.
- Morotti RA, Jain D. Pediatric Cholestatic Disorders: Approach to Pathologic Diagnosis. Surgical Pathology Clinics 2013, 6: 205-25. PMID: 26838972, DOI: 10.1016/j.path.2013.03.001.
- Liu J, Halene S, Yang M, Iqbal J, Yang R, Mehal WZ, Chuang WL, Jain D, Yuen T, Sun L, Zaidi M, Mistry PK. Gaucher disease gene GBA functions in immune regulation. Proceedings Of The National Academy Of Sciences Of The United States Of America 2012, 109: 10018-23. PMID: 22665763, PMCID: PMC3382552, DOI: 10.1073/pnas.1200941109.
- Lo SM, Choi M, Liu J, Jain D, Boot RG, Kallemeijn WW, Aerts JM, Pashankar F, Kupfer GM, Mane S, Lifton RP, Mistry PK. Phenotype diversity in type 1 Gaucher disease: discovering the genetic basis of Gaucher disease/hematologic malignancy phenotype by individual genome analysis. Blood 2012, 119: 4731-40. PMID: 22493294, PMCID: PMC3367875, DOI: 10.1182/blood-2011-10-386862.
- Singhi AD, Jain D, Kakar S, Wu TT, Yeh MM, Torbenson M. Reticulin loss in benign fatty liver: an important diagnostic pitfall when considering a diagnosis of hepatocellular carcinoma. The American Journal Of Surgical Pathology 2012, 36: 710-5. PMID: 22498821, DOI: 10.1097/PAS.0b013e3182495c73.
- Chan ES, Alexander J, Swanson PE, Jain D, Yeh MM. PDX-1, CDX-2, TTF-1, and CK7: a reliable immunohistochemical panel for pancreatic neuroendocrine neoplasms. The American Journal Of Surgical Pathology 2012, 36: 737-43. PMID: 22498824, DOI: 10.1097/PAS.0b013e31824aba59.
- Sethasine S, Jain D, Groszmann RJ, Garcia-Tsao G. Quantitative histological-hemodynamic correlations in cirrhosis. Hepatology (Baltimore, Md.) 2012, 55: 1146-53. PMID: 22109744, PMCID: PMC3721182, DOI: 10.1002/hep.24805.
- Aslanian H, Chander B, Robert M, Cooper D, Proctor D, Seropian S, Jain D. Prospective evaluation of acute graft-versus-host disease. Digestive Diseases And Sciences 2012, 57: 720-5. PMID: 22011927, DOI: 10.1007/s10620-011-1938-x.
- Barbieri AL, Jain D, Gobel S, Kenney B. Wagner-Meissner corpuscle proliferation: a unique cause of colon polyps. International Journal Of Surgical Pathology 2012, 20: 79-82. PMID: 21632642, DOI: 10.1177/1066896911408723.
- Cheng SX, Gathungu G, Pashankar D, Jain D, Husain SZ. Jejunal adaptation in a prepubertal boy after total ileal resection and jejunostomy placement: a four-year follow-up. Journal Of Clinical Gastroenterology 2011, 45: 846-9. PMID: 21552141, PMCID: PMC4425287, DOI: 10.1097/MCG.0b013e318214b2d9.
- Anderson BE, Tang AL, Wang Y, Froicu M, Rothstein D, McNiff JM, Jain D, Demetris AJ, Farber DL, Shlomchik WD, Shlomchik MJ. Enhancing alloreactivity does not restore GVHD induction but augments skin graft rejection by CD4⁺ effector memory T cells. European Journal Of Immunology 2011, 41: 2782-92. PMID: 21660940, PMCID: PMC3517133, DOI: 10.1002/eji.201141678.
- Gancayco J, Siddiqui UD, Jain D, Aslanian HR. Narrow band imaging features and pathological correlations of sessile serrated polyps. The American Journal Of Gastroenterology 2011, 106: 1559-60. PMID: 21811282, DOI: 10.1038/ajg.2011.122.
- Kenney B, Singh G, Salem RR, Paterno F, Robert ME, Jain D. Pseudointraductal papillary mucinous neoplasia caused by microscopic periductal endocrine tumors of the pancreas: a report of 3 cases. Human Pathology 2011, 42: 1034-41. PMID: 21292301, DOI: 10.1016/j.humpath.2010.09.018.
- Zeng H, Yu H, Lu L, Jain D, Kidd MS, Saif MW, Chanock SJ, Hartge P, Risch HA. Genetic effects and modifiers of radiotherapy and chemotherapy on survival in pancreatic cancer. Pancreas 2011, 40: 657-63. PMID: 21487324, PMCID: PMC3116071, DOI: 10.1097/MPA.0b013e31821268d1.
- Walther Z, Jain D. Molecular pathology of hepatic neoplasms: classification and clinical significance. Pathology Research International 2011, 2011: 403929. PMID: 21559202, PMCID: PMC3090128, DOI: 10.4061/2011/403929.
- Chander B, Fiedler P, Jain D. Eosinophilic myenteric ganglionitis: a case of intestinal pseudo-obstruction in a 93-year-old female. Journal Of Clinical Gastroenterology 2011, 45: 314-6. PMID: 20921901, DOI: 10.1097/MCG.0b013e3181f5978a.
- Li H, Matte-Martone C, Tan HS, Venkatesan S, McNiff J, Demetris AJ, Jain D, Lakkis F, Rothstein D, Shlomchik WD. Graft-versus-host disease is independent of innate signaling pathways triggered by pathogens in host hematopoietic cells. Journal Of Immunology (Baltimore, Md. : 1950) 2011, 186: 230-41. PMID: 21098219, PMCID: PMC5822434, DOI: 10.4049/jimmunol.1002965.
- Mistry PK, Liu J, Yang M, Nottoli T, McGrath J, Jain D, Zhang K, Keutzer J, Chuang WL, Mehal WZ, Zhao H, Lin A, Mane S, Liu X, Peng YZ, Li JH, Agrawal M, Zhu LL, Blair HC, Robinson LJ, Iqbal J, Sun L, Zaidi M. Glucocerebrosidase gene-deficient mouse recapitulates Gaucher disease displaying cellular and molecular dysregulation beyond the macrophage. Proceedings Of The National Academy Of Sciences Of The United States Of America 2010, 107: 19473-8. PMID: 20962279, PMCID: PMC2984187, DOI: 10.1073/pnas.1003308107.
- Matte-Martone C, Wang X, Anderson B, Jain D, Demetris AJ, McNiff J, Shlomchik MJ, Shlomchik WD. Recipient B cells are not required for graft-versus-host disease induction. Biology Of Blood And Marrow Transplantation : Journal Of The American Society For Blood And Marrow Transplantation 2010, 16: 1222-30. PMID: 20338255, PMCID: PMC3135976, DOI: 10.1016/j.bbmt.2010.03.015.
- Parkash V, Bifulco C, Feinn R, Concato J, Jain D. To count and how to count, that is the question: interobserver and intraobserver variability among pathologists in lymph node counting. American Journal Of Clinical Pathology 2010, 134: 42-9. PMID: 20551265, DOI: 10.1309/AJCPO92DZMUCGEUF.
- Stein P, Yu H, Jain D, Mistry PK. Hyperferritinemia and iron overload in type 1 Gaucher disease. American Journal Of Hematology 2010, 85: 472-6. PMID: 20575041, PMCID: PMC2895498, DOI: 10.1002/ajh.21721.
- Orabi AI, Shah AU, Ahmad MU, Choo-Wing R, Parness J, Jain D, Bhandari V, Husain SZ. Dantrolene mitigates caerulein-induced pancreatitis in vivo in mice. American Journal Of Physiology. Gastrointestinal And Liver Physiology 2010, 299: G196-204. PMID: 20448143, PMCID: PMC2904115, DOI: 10.1152/ajpgi.00498.2009.
- Lo SM, Stein P, Mullaly S, Bar M, Jain D, Pastores GM, Mistry PK. Expanding spectrum of the association between Type 1 Gaucher disease and cancers: a series of patients with up to 3 sequential cancers of multiple types--correlation with genotype and phenotype. American Journal Of Hematology 2010, 85: 340-5. PMID: 20425796, PMCID: PMC2875938, DOI: 10.1002/ajh.21684.
- Jain D, Ahrens W, Finkelstein S. Molecular evidence for the neoplastic potential of hepatic Von-Meyenburg complexes. Applied Immunohistochemistry & Molecular Morphology : AIMM / Official Publication Of The Society For Applied Immunohistochemistry 2010, 18: 166-71. PMID: 19770706, DOI: 10.1097/PAI.0b013e3181b94fd8.
- Van Patten K, Parkash V, Jain D. Cadherin expression in gastrointestinal tract endometriosis: possible role in deep tissue invasion and development of malignancy. Modern Pathology : An Official Journal Of The United States And Canadian Academy Of Pathology, Inc 2010, 23: 38-44. PMID: 19898423, DOI: 10.1038/modpathol.2009.127.
- Phatak UP, Seo-Mayer P, Jain D, Selbst M, Husain S, Pashankar DS. Mycophenolate mofetil-induced colitis in children. Journal Of Clinical Gastroenterology 2009, 43: 967-9. PMID: 19609219, DOI: 10.1097/MCG.0b013e3181a8754d.
- Shah AU, Sarwar A, Orabi AI, Gautam S, Grant WM, Park AJ, Shah AU, Liu J, Mistry PK, Jain D, Husain SZ. Protease activation during in vivo pancreatitis is dependent on calcineurin activation. American Journal Of Physiology. Gastrointestinal And Liver Physiology 2009, 297: G967-73. PMID: 20501444, PMCID: PMC2777459, DOI: 10.1152/ajpgi.00181.2009.
- Kakar S, Chen X, Ho C, Burgart LJ, Adeyi O, Jain D, Sahai V, Ferrell LD. Chromosomal abnormalities determined by comparative genomic hybridization are helpful in the diagnosis of atypical hepatocellular neoplasms. Histopathology 2009, 55: 197-205. PMID: 19694827, PMCID: PMC3727398, DOI: 10.1111/j.1365-2559.2009.03343.x.
- Selbst MK, Ahrens WA, Robert ME, Friedman A, Proctor DD, Jain D. Spectrum of histologic changes in colonic biopsies in patients treated with mycophenolate mofetil. Modern Pathology : An Official Journal Of The United States And Canadian Academy Of Pathology, Inc 2009, 22: 737-43. PMID: 19329937, DOI: 10.1038/modpathol.2009.44.
- Zheng H, Matte-Martone C, Jain D, McNiff J, Shlomchik WD. Central memory CD8+ T cells induce graft-versus-host disease and mediate graft-versus-leukemia. Journal Of Immunology (Baltimore, Md. : 1950) 2009, 182: 5938-48. PMID: 19414745, DOI: 10.4049/jimmunol.0802212.
- Concato J, Jain D, Uchio E, Risch H, Li WW, Wells CK. Molecular markers and death from prostate cancer. Annals Of Internal Medicine 2009, 150: 595-603. PMID: 19414838, DOI: 10.7326/0003-4819-150-9-200905050-00005.
- Hakim W, Sheikh S, Inayat I, Caldwell C, Smith D, Lorber M, Friedman A, Jain D, Bia M, Formica R, Mehal W. HCV response in patients with end stage renal disease treated with combination pegylated interferon alpha-2a and ribavirin. Journal Of Clinical Gastroenterology 2009, 43: 477-81. PMID: 19142165, PMCID: PMC3715868, DOI: 10.1097/MCG.0b013e318180803a.
- Kamath A, Helie M, Bifulco CB, Li WW, Concato J, Jain D. Lack of immunohistochemical detection of VEGF in prostate carcinoma. Applied Immunohistochemistry & Molecular Morphology : AIMM / Official Publication Of The Society For Applied Immunohistochemistry 2009, 17: 227-32. PMID: 19098681, DOI: 10.1097/PAI.0b013e31818f9e7f.
- Ahmad I, Iyer A, Marginean CE, Yeh MM, Ferrell L, Qin L, Bifulco CB, Jain D. Diagnostic use of cytokeratins, CD34, and neuronal cell adhesion molecule staining in focal nodular hyperplasia and hepatic adenoma. Human Pathology 2009, 40: 726-34. PMID: 19157505, DOI: 10.1016/j.humpath.2008.10.018.
- Kakar S, Chen X, Ho C, Burgart LJ, Sahai V, Dachrut S, Yabes A, Jain D, Ferrell LD. Chromosomal changes in fibrolamellar hepatocellular carcinoma detected by array comparative genomic hybridization. Modern Pathology : An Official Journal Of The United States And Canadian Academy Of Pathology, Inc 2009, 22: 134-41. PMID: 18997738, DOI: 10.1038/modpathol.2008.178.
- Rogart JN, Jain D, Siddiqui UD, Oren T, Lim J, Jamidar P, Aslanian H. Narrow-band imaging without high magnification to differentiate polyps during real-time colonoscopy: improvement with experience. Gastrointestinal Endoscopy 2008, 68: 1136-45. PMID: 18691708, DOI: 10.1016/j.gie.2008.04.035.
- Zipprich A, Loureiro-Silva MR, Jain D, D'Silva I, Groszmann RJ. Nitric oxide and vascular remodeling modulate hepatic arterial vascular resistance in the isolated perfused cirrhotic rat liver. Journal Of Hepatology 2008, 49: 739-45. PMID: 18804307, DOI: 10.1016/j.jhep.2008.06.027.
- Kamath A, Mehal W, Jain D. Colchicine-associated ring mitosis in liver biopsy and their clinical implications. Journal Of Clinical Gastroenterology 2008, 42: 1060-2. PMID: 18391833, PMCID: PMC3730132, DOI: 10.1097/MCG.0b013e31803815b4.
- Kenney BC, Jain D. Identification of lymphatics within the colonic lamina propria in inflammation and neoplasia using the monoclonal antibody D2-40. The Yale Journal Of Biology And Medicine 2008, 81: 103-13. PMID: 18827885, PMCID: PMC2553648.
- Iyer A, Robert ME, Bifulco CB, Salem RR, Jain D. Different cytokeratin and neuronal cell adhesion molecule staining patterns in focal nodular hyperplasia and hepatic adenoma and their significance. Human Pathology 2008, 39: 1370-7. PMID: 18602664, PMCID: PMC3738023, DOI: 10.1016/j.humpath.2008.01.015.
- Kenney B, Tormey CA, Qin L, Sosa JA, Jain D, Neto A. Adult nesidioblastosis. Clinicopathologic correlation between pre-operative selective arterial calcium stimulation studies and post-operative pathologic findings. JOP : Journal Of The Pancreas 2008, 9: 504-11. PMID: 18648143.
- Chetty R, Jain D, Serra S. p120 catenin reduction and cytoplasmic relocalization leads to dysregulation of E-cadherin in solid pseudopapillary tumors of the pancreas. American Journal Of Clinical Pathology 2008, 130: 71-6. PMID: 18550473, DOI: 10.1309/FEYD99TXC4LMYVA5.
- Anderson BE, Taylor PA, McNiff JM, Jain D, Demetris AJ, Panoskaltsis-Mortari A, Ager A, Blazar BR, Shlomchik WD, Shlomchik MJ. Effects of donor T-cell trafficking and priming site on graft-versus-host disease induction by naive and memory phenotype CD4 T cells. Blood 2008, 111: 5242-51. PMID: 18285547, PMCID: PMC2384145, DOI: 10.1182/blood-2007-09-107953.
- Matte-Martone C, Liu J, Jain D, McNiff J, Shlomchik WD. CD8+ but not CD4+ T cells require cognate interactions with target tissues to mediate GVHD across only minor H antigens, whereas both CD4+ and CD8+ T cells require direct leukemic contact to mediate GVL. Blood 2008, 111: 3884-92. PMID: 18223170, PMCID: PMC2275040, DOI: 10.1182/blood-2007-11-125294.
- Carmack S, Taddei T, Robert ME, Mistry P, Jain D. Increased T-cell sinusoidal lymphocytosis in liver biopsies in patients with chronic hepatitis C and mixed cryoglobulinemia. The American Journal Of Gastroenterology 2008, 103: 705-11. PMID: 17970837, DOI: 10.1111/j.1572-0241.2007.01603.x.
- Zheng H, Matte-Martone C, Li H, Anderson BE, Venketesan S, Sheng Tan H, Jain D, McNiff J, Shlomchik WD. Effector memory CD4+ T cells mediate graft-versus-leukemia without inducing graft-versus-host disease. Blood 2008, 111: 2476-84. PMID: 18045967, PMCID: PMC2234071, DOI: 10.1182/blood-2007-08-109678.
- Gallagher AR, Esquivel EL, Briere TS, Tian X, Mitobe M, Menezes LF, Markowitz GS, Jain D, Onuchic LF, Somlo S. Biliary and pancreatic dysgenesis in mice harboring a mutation in Pkhd1. The American Journal Of Pathology 2008, 172: 417-29. PMID: 18202188, PMCID: PMC2312372, DOI: 10.2353/ajpath.2008.070381.
- Anderson BE, Zheng H, Taylor PA, Matte-Martone C, McNiff JM, Jain D, Demetris AJ, Panoskaltsis-Mortari A, Ager A, Blazar BR, Shlomchik MJ, Shlomchik WD. Memory T cells in GVHD and GVL. Biology Of Blood And Marrow Transplantation : Journal Of The American Society For Blood And Marrow Transplantation 2008, 14: 19-20. PMID: 19418622.
- Concato J, Jain D, Li WW, Risch HA, Uchio EM, Wells CK. Molecular markers and mortality in prostate cancer. BJU International 2007, 100: 1259-63. PMID: 17850375, DOI: 10.1111/j.1464-410X.2007.07136.x.
- Dranoff JA, Kruglov EA, Abreu-Lanfranco O, Nguyen T, Arora G, Jain D. Prevention of liver fibrosis by the purinoceptor antagonist pyridoxal-phosphate-6-azophenyl-2',4'-disulfonate (PPADS). In Vivo (Athens, Greece) 2007, 21: 957-65. PMID: 18210741.
- Neto AG, Dainiak C, Qin L, Salem RR, Jain D. Intraductal papillary cholangiocarcinoma associated with von Meyenberg complexes: a case report. Digestive Diseases And Sciences 2007, 52: 2643-5. PMID: 17394067, DOI: 10.1007/s10620-007-9777-5.
- Marginean EC, Bennick M, Cyczk J, Robert ME, Jain D. Gastric siderosis: patterns and significance. The American Journal Of Surgical Pathology 2006, 30: 514-20. PMID: 16625099, DOI: 10.1097/00000478-200604000-00013.
- Nagula S, Jain D, Groszmann RJ, Garcia-Tsao G. Histological-hemodynamic correlation in cirrhosis-a histological classification of the severity of cirrhosis. Journal Of Hepatology 2006, 44: 111-7. PMID: 16274836, DOI: 10.1016/j.jhep.2005.07.036.
- Kakar S, Burgart LJ, Batts KP, Garcia J, Jain D, Ferrell LD. Clinicopathologic features and survival in fibrolamellar carcinoma: comparison with conventional hepatocellular carcinoma with and without cirrhosis. Modern Pathology : An Official Journal Of The United States And Canadian Academy Of Pathology, Inc 2005, 18: 1417-23. PMID: 15920538, DOI: 10.1038/modpathol.3800449.
- Jain D, Eslami-Varzaneh F, Takano AM, Ayer U, Umashankar R, Muller R, Klimstra DS. Composite glandular and endocrine tumors of the stomach with pancreatic acinar differentiation. The American Journal Of Surgical Pathology 2005, 29: 1524-9. PMID: 16224221, DOI: 10.1097/01.pas.0000169498.89035.f9.
- Sheela H, Seela S, Caldwell C, Boyer JL, Jain D. Liver biopsy: evolving role in the new millennium. Journal Of Clinical Gastroenterology 2005, 39: 603-10. PMID: 16000929, DOI: 10.1097/01.mcg.0000170742.59134.60.
- Mariappan MR, Fadare O, Jain D, Chacho MS. Diagnostic intraoperative imprint cytology of a solid pseudopapillary tumor of the pancreas. Diagnostic Cytopathology 2005, 32: 351-2. PMID: 15880718, DOI: 10.1002/dc.20194.
- Achneck HE, Wong IY, Kim PJ, Fernandes MA, Walther Z, Seymour NE, Jain D. Ileostomy adenocarcinomas in the setting of ulcerative colitis. Journal Of Clinical Gastroenterology 2005, 39: 396-400. PMID: 15815208, DOI: 10.1097/01.mcg.0000159216.39795.4a.
- Anderson BE, McNiff JM, Jain D, Blazar BR, Shlomchik WD, Shlomchik MJ. Distinct roles for donor- and host-derived antigen-presenting cells and costimulatory molecules in murine chronic graft-versus-host disease: requirements depend on target organ. Blood 2005, 105: 2227-34. PMID: 15522961, DOI: 10.1182/blood-2004-08-3032.
- Dranoff JA, Kruglov EA, Toure J, Braun N, Zimmermann H, Jain D, Knowles AF, Sévigny J. Ectonucleotidase NTPDase2 is selectively down-regulated in biliary cirrhosis. Journal Of Investigative Medicine : The Official Publication Of The American Federation For Clinical Research 2004, 52: 475-82. PMID: 15651265, DOI: 10.1136/jim-52-07-42.
- Kaplan DH, Anderson BE, McNiff JM, Jain D, Shlomchik MJ, Shlomchik WD. Target antigens determine graft-versus-host disease phenotype. Journal Of Immunology (Baltimore, Md. : 1950) 2004, 173: 5467-75. PMID: 15494494, DOI: 10.4049/jimmunol.173.9.5467.
- Hong-Curtis J, Yeh MM, Jain D, Lee JH. Rapid progression of autoimmune hepatitis in the background of primary sclerosing cholangitis. Journal Of Clinical Gastroenterology 2004, 38: 906-9. PMID: 15492611, DOI: 10.1097/00004836-200411000-00015.
- Gustavo LC, Robert ME, Lamps LW, Lagarde SP, Jain D. Isolated gastric malakoplakia: a case report and review of the literature. Archives Of Pathology & Laboratory Medicine 2004, 128: e153-6. PMID: 15504079, DOI: 10.5858/2004-128-e153-IGMACR.
- Matte CC, Liu J, Cormier J, Anderson BE, Athanasiadis I, Jain D, McNiff J, Shlomchik WD. Donor APCs are required for maximal GVHD but not for GVL. Nature Medicine 2004, 10: 987-92. PMID: 15286785, DOI: 10.1038/nm1089.
- Prasad P, Salem RR, Mangla R, Aslanian H, Jain D, Lee J. Lymphoplasmacytic sclerosing pancreato-cholangitis: a case report and review of the literature. The Yale Journal Of Biology And Medicine 2004, 77: 143-8. PMID: 15989743, PMCID: PMC2259126.
- Yeh MM, Tang LH, Wang S, Robert ME, Zheng W, Jain D. Inhibin expression in ovarian-type stroma in mucinous cystic neoplasms of the pancreas. Applied Immunohistochemistry & Molecular Morphology : AIMM / Official Publication Of The Society For Applied Immunohistochemistry 2004, 12: 148-52. PMID: 15354741, DOI: 10.1097/00129039-200406000-00009.
- Eslami-Varzaneh F, Washington K, Robert ME, Kashgarian M, Goldblum JR, Jain D. Benign fibroblastic polyps of the colon: a histologic, immunohistochemical, and ultrastructural study. The American Journal Of Surgical Pathology 2004, 28: 374-8. PMID: 15104300, DOI: 10.1097/00000478-200403000-00010.
- Marginean EC, Jain D. Alcoholic pancreatitis: is it a priori chronic disease? Journal Of Clinical Gastroenterology 2004, 38: 203-5. PMID: 15128063, DOI: 10.1097/00004836-200403000-00002.
- Mariappan MR, Fadare O, Jain D. Sebaceous differentiation in salivary glands. Archives Of Pathology & Laboratory Medicine 2004, 128: 245-6. PMID: 14736269, DOI: 10.5858/2004-128-245-SDISG.
- Jain D, Robert ME, Navarro V, Friedman AL, Crawford JM. Total fibrous obliteration of main portal vein and portal foam cell venopathy in chronic hepatic allograft rejection. Archives Of Pathology & Laboratory Medicine 2004, 128: 64-7. PMID: 14692809, DOI: 10.5858/2004-128-64-TFOOMP.
- Koullias GJ, Korkolis DP, Hatzaras IS, Elefteriades JA, Jain D. Immunohistochemical testing for Helicobacter pylori infection in ascending aortic aneurysms and penetrating aortic ulcers. The American Journal Of Cardiology 2004, 93: 122-3. PMID: 14697486, DOI: 10.1016/j.amjcard.2003.09.025.
- Jain D, Moussa K, Tandon M, Culpepper-Morgan J, Proctor DD. Role of interstitial cells of Cajal in motility disorders of the bowel. The American Journal Of Gastroenterology 2003, 98: 618-24. PMID: 12650797, DOI: 10.1111/j.1572-0241.2003.07295.x.
- Calhoun BC, Gomes F, Robert ME, Jain D. Sampling error in the standard evaluation of endoscopic colonic biopsies. The American Journal Of Surgical Pathology 2003, 27: 254-7. PMID: 12548174, DOI: 10.1097/00000478-200302000-00016.
- Jain D, Martel M, Reyes-Múgica M, Parkash V. Heterotopic nephrogenic rests in the colon and multiple congenital anomalies: possibly related association. Pediatric And Developmental Pathology : The Official Journal Of The Society For Pediatric Pathology And The Paediatric Pathology Society 2002, 5: 587-91. PMID: 12375130, DOI: 10.1007/s10024-002-0055-4.
- Jain D. Diagnosis of hepatocellular carcinoma: fine needle aspiration cytology or needle core biopsy. Journal Of Clinical Gastroenterology 2002, 35: S101-8. PMID: 12394213, DOI: 10.1097/00004836-200211002-00006.
- Kruglov EA, Jain D, Dranoff JA. Isolation of primary rat liver fibroblasts. Journal Of Investigative Medicine : The Official Publication Of The American Federation For Clinical Research 2002, 50: 179-84. PMID: 12033282, DOI: 10.2310/6650.2002.33431.
- Tang LH, Hui P, Garcia-Tsao G, Salem RR, Jain D. Multiple angiomyolipomata of the liver: a case report. Modern Pathology : An Official Journal Of The United States And Canadian Academy Of Pathology, Inc 2002, 15: 167-71. PMID: 11850546, DOI: 10.1038/modpathol.3880509.
- Robert ME, Singh SK, Ikuma M, Jain D, Ardito T, Binder HJ. Morphology of isolated colonic crypts. Cells, Tissues, Organs 2001, 168: 246-51. PMID: 11275691, DOI: 10.1159/000047841.
- Jain D, Bowlus CL, Anderson JM, Robert ME. Granular cells as a marker of early amiodarone hepatotoxicity. Journal Of Clinical Gastroenterology 2000, 31: 241-3. PMID: 11034006, DOI: 10.1097/00004836-200010000-00012.
- Garcia-Tsao G, Korzenik JR, Young L, Henderson KJ, Jain D, Byrd B, Pollak JS, White RI. Liver disease in patients with hereditary hemorrhagic telangiectasia. The New England Journal Of Medicine 2000, 343: 931-6. PMID: 11006369, DOI: 10.1056/NEJM200009283431305.
- Jain D, Sarode VR, Abdul-Karim FW, Homer R, Robert ME. Evidence for the neoplastic transformation of Von-Meyenburg complexes. The American Journal Of Surgical Pathology 2000, 24: 1131-9. PMID: 10935654, DOI: 10.1097/00000478-200008000-00011.