1
Yale Emergency Medicine
Yale New Haven Hospital
20 York Street, Ste South Pavilion Suite 218
New Haven, CT 06510
1 of 2
- Yale Emergency MedicineYale New Haven Hospital20 York Street, Ste South Pavilion Suite 218New Haven, CT 06510
- Yale Emergency MedicineYale New Haven Shoreline Medical Center111 Goose LaneGuilford, CT 06437
Charles Wira, MD
Internal Medicine, Emergency Medicine
Telehealth is available
Patient type treated
Adult
Accepting new patients
Yes
Referral required
Not Applicable
Board Certified in
Emergency Medicine
Titles
- Associate Professor Term
- Liaison, Yale-New Haven Stroke Program
Education & Training
- ResidentHenry Ford Hospital (2005)
- MDDartmouth School of Medicine (2000)
- BSUniversity of New Hampshire (1993)
Languages Spoken
- English
- Español (Spanish)
Additional Information
Honors & Recognitions
- Member, Stroke Council Leadership Committee: AHA/ASA (2020)
- Chair, Emergency Neurovascular Care Committee: AHA/ASA (2020)
- Chair: State of Connecticut Stroke Task Force (2016)
- Chair: NorthEast Cerebrovascular Consortium (NorthEast AHA/ASA) (2014)
- 2011 Residency Teacher of the Year--Yale DEM: Yale DEM Residents (2011)
- Co-Chair of the Acute Stroke Section: NECC/AHA/ASA
Board Certifications
- AB of Emergency Medicine, Emergency Medicine (2006, recertified: 2017)
Publications
- Rajendram P, Notario L, Reid C, Wira CR, Suarez JI, Weingart SD, Khosravani H. Crisis Resource Management and High-Performing Teams in Hyperacute Stroke Care. Neurocritical Care 2020, 33: 338-346. PMID: 32794144, PMCID: PMC7426067, DOI: 10.1007/s12028-020-01057-4.
- Jasne AS, Chojecka P, Maran I, Mageid R, Eldokmak M, Zhang Q, Nystrom K, Vlieks K, Askenase M, Petersen N, Falcone GJ, Wira CR, Lleva P, Zeevi N, Narula R, Amin H, Navaratnam D, Loomis C, Hwang DY, Schindler J, Hebert R, Matouk C, Krumholz HM, Spudich S, Sheth KN, Sansing LH, Sharma R. Stroke Code Presentations, Interventions, and Outcomes Before and During the COVID-19 Pandemic. Stroke; A Journal Of Cerebral Circulation 2020, 51: 2664-2673. PMID: 32755347, PMCID: PMC7446978, DOI: 10.1161/STR.0000000000000347.
- Wira CR, Goyal M, Southerland AM, Sheth KN, McNair ND, Khosravani H, Leonard A, Panagos P. Pandemic Guidance for Stroke Centers Aiding COVID-19 Treatment Teams. Stroke; A Journal Of Cerebral Circulation 2020, 51: 2587-2592. PMID: 32716826, PMCID: PMC7326321, DOI: 10.1161/STROKEAHA.120.030749.
- Goyal M, Ospel JM, Southerland AM, Wira C, Amin-Hanjani S, Fraser JF, Panagos P. Prehospital Triage of Acute Stroke Patients During the COVID-19 Pandemic. Stroke; A Journal Of Cerebral Circulation 2020, 51: 2263-2267. PMID: 32401680, DOI: 10.1161/STROKEAHA.120.030340.
- Liu RB, Bogucki S, Marcolini EG, Yu CY, Wira CR, Kalam S, Daley J, Moore CL, Cone DC. Guiding Cardiopulmonary Resuscitation with Focused Echocardiography: A Report of Five Cases. Prehospital Emergency Care : Official Journal Of The National Association Of EMS Physicians And The National Association Of State EMS Directors 2020, 24: 297-302. PMID: 31150302, DOI: 10.1080/10903127.2019.1626955.
- Wu X, Hughes DR, Gandhi D, Matouk CC, Sheth K, Schindler J, Wira C, Wintermark M, Sanelli P, Malhotra A. CT Angiography for Triage of Patients with Acute Minor Stroke: A Cost-effectiveness Analysis. Radiology 2020, 294: 580-588. PMID: 31934828, DOI: 10.1148/radiol.2019191238.
- Wira CR, Melluzzo S, Beasley TM, Magdon-Ismail Z, Day D, Madsen TE, McCullough LD, Stein J, Schwamm LH, Gropen T. Stroke Center Certification and Performance: A Longitudinal Analysis of the Northeast Cerebrovascular Consortium Region. The Yale Journal Of Biology And Medicine 2019, 92: 587-596. PMID: 31866774, PMCID: PMC6913814.
- Madsen TE, Wira CR. The Future of Minor Stroke and Transient Ischemic Attack: The RAVEN Approach Is Promising but Not Ready for Prime Time. Annals Of Emergency Medicine 2019, 74: 572-574. PMID: 31543123, DOI: 10.1016/j.annemergmed.2019.08.458.
- Belsky JB, Wira CR, Jacob V, Sather JE, Lee PJ. A review of micronutrients in sepsis: the role of thiamine, l-carnitine, vitamin C, selenium and vitamin D. Nutrition Research Reviews 2018, 31: 281-290. PMID: 29984680, DOI: 10.1017/S0954422418000124.
- Wira CR, Madsen TE, Chang BP, Nomura JT, Marcolini E, Gentile NT, Schreyer KE, Merck LH, Siket M, Greenberg K, Zammit CG, Jauch EC, Fernanda Bellolio M. Is There a Neurologist in the House? A Summary of the Current State of Neurovascular Rotations for Emergency Medicine Residents. AEM Education And Training 2018, 2: S56-S67. PMID: 30607380, PMCID: PMC6304277, DOI: 10.1002/aet2.10200.
- Swenson KE, Dziura JD, Aydin A, Reynolds J, Wira CR. Evaluation of a novel 5-group classification system of sepsis by vasopressor use and initial serum lactate in the emergency department. Internal And Emergency Medicine 2018, 13: 257-268. PMID: 28132131, DOI: 10.1007/s11739-017-1607-y.
- Chang BP, Wira C, Miller J, Akhter M, Barth BE, Willey J, Nentwich L, Madsen T. Neurology Concepts: Young Women and Ischemic Stroke-Evaluation and Management in the Emergency Department. Academic Emergency Medicine : Official Journal Of The Society For Academic Emergency Medicine 2018, 25: 54-64. PMID: 28646558, PMCID: PMC6415947, DOI: 10.1111/acem.13243.
- McGregor AJ, Beauchamp GA, Wira CR, Perman SM, Safdar B. Sex as a Biological Variable in Emergency Medicine Research and Clinical Practice: A Brief Narrative Review. The Western Journal Of Emergency Medicine 2017, 18: 1079-1090. PMID: 29085541, PMCID: PMC5654878, DOI: 10.5811/westjem.2017.8.34997.
- Miller JB, Lewandowski C, Wira CR, Taylor A, Burmeister C, Welch R. Volume of Plasma Expansion and Functional Outcomes in Stroke. Neurocritical Care 2017, 26: 191-195. PMID: 27629275, DOI: 10.1007/s12028-016-0316-0.
- Miller JB, Merck LH, Wira CR, Meurer WJ, Schrock JW, Nomura JT, Siket MS, Madsen TE, Wright DW, Panagos PD, Lewandowski C. The Advanced Reperfusion Era: Implications for Emergency Systems of Ischemic Stroke Care. Annals Of Emergency Medicine 2017, 69: 192-201. PMID: 27600649, DOI: 10.1016/j.annemergmed.2016.06.042.
- Giberson B, Uber A, F Gaieski D, Miller JB, Wira C, Berg K, Giberson T, Cocchi MN, S Abella B, Donnino MW. When to Stop CPR and When to Perform Rhythm Analysis: Potential Confusion Among ACLS Providers. Journal Of Intensive Care Medicine 2016, 31: 537-43. PMID: 25542192, DOI: 10.1177/0885066614561589.
- Wira CR, Swenson KE. Composition of the Sepsis Definitions Task Force. JAMA 2016, 316: 460. PMID: 27458964, DOI: 10.1001/jama.2016.6371.
- Asuzu D, Nystr¿m K, Amin H, Schindler J, Wira C, Greer D, Chi NF, Halliday J, Sheth KN. Validation of TURN, a simple predictor of symptomatic intracerebral hemorrhage after IV thrombolysis. Clinical Neurology And Neurosurgery 2016, 146: 71-5. PMID: 27152469, DOI: 10.1016/j.clineuro.2016.04.017.
- Asuzu D, Nyström K, Sreekrishnan A, Schindler J, Wira C, Greer D, Halliday J, Kimberly WT, Sheth KN. TURN Score Predicts 24-Hour Cerebral Edema After IV Thrombolysis. Neurocritical Care 2016, 24: 381-8. PMID: 26341364, DOI: 10.1007/s12028-015-0198-6.
- Arch AE, Weisman DC, Coca S, Nystrom KV, Wira CR, Schindler JL. Missed Ischemic Stroke Diagnosis in the Emergency Department by Emergency Medicine and Neurology Services. Stroke; A Journal Of Cerebral Circulation 2016, 47: 668-73. PMID: 26846858, DOI: 10.1161/STROKEAHA.115.010613.
- Asuzu D, Nystr¿m K, Schindler J, Wira C, Greer D, Halliday J, Sheth KN. Risk rtPA: An iOS mobile application based on TURN for predicting 90-day outcome after IV thrombolysis. Clinical Neurology And Neurosurgery 2016, 142: 148-152. PMID: 26875069, DOI: 10.1016/j.clineuro.2016.01.030.
- Asuzu D, Nystr¿m K, Amin H, Schindler J, Wira C, Greer D, Chi NF, Halliday J, Sheth KN. On- versus Off-Hour Patient Cohorts at a Primary Stroke Center: Onset-to-Treatment Duration and Clinical Outcomes after IV Thrombolysis. Journal Of Stroke And Cerebrovascular Diseases : The Official Journal Of National Stroke Association 2016, 25: 447-51. PMID: 26654664, DOI: 10.1016/j.jstrokecerebrovasdis.2015.10.017.
- Asuzu D, Nyström K, Amin H, Schindler J, Wira C, Greer D, Chi NF, Halliday J, Sheth KN. Cohort-Based Identification of Predictors of Symptomatic Intracerebral Hemorrhage After IV Thrombolysis. Neurocritical Care 2015, 23: 394-400. PMID: 25691004, DOI: 10.1007/s12028-015-0121-1.
- Bhat SR, Swenson KE, Francis MW, Wira CR. Lactate Clearance Predicts Survival Among Patients in the Emergency Department with Severe Sepsis. The Western Journal Of Emergency Medicine 2015, 16: 1118-26. PMID: 26759665, PMCID: PMC4703153, DOI: 10.5811/westjem.2015.10.27577.
- Asuzu D, Nyström K, Amin H, Schindler J, Wira C, Greer D, Chi NF, Halliday J, Sheth KN. TURN: A Simple Predictor of Symptomatic Intracerebral Hemorrhage After IV Thrombolysis. Neurocritical Care 2015, 23: 166-71. PMID: 25869481, DOI: 10.1007/s12028-015-0131-z.
- Asuzu D, Nyström K, Schindler J, Wira C, Greer D, Halliday J, Sheth KN. TURN Score Predicts 90-day Outcome in Acute Ischemic Stroke Patients After IV Thrombolysis. Neurocritical Care 2015, 23: 172-8. PMID: 26032809, DOI: 10.1007/s12028-015-0154-5.
- Sivaraju A, Gilmore EJ, Wira CR, Stevens A, Rampal N, Moeller JJ, Greer DM, Hirsch LJ, Gaspard N. Prognostication of post-cardiac arrest coma: early clinical and electroencephalographic predictors of outcome. Intensive Care Medicine 2015, 41: 1264-72. PMID: 25940963, DOI: 10.1007/s00134-015-3834-x.
- Miller JB, Heitsch L, Siket MS, Schrock JW, Wira CR, Lewandowski C, Madsen TE, Merck LH, Wright DW. The Emergency Medicine Debate on tPA for Stroke: What Is Best for Our Patients? Efficacy in the First Three Hours. Academic Emergency Medicine : Official Journal Of The Society For Academic Emergency Medicine 2015, 22: 852-5. PMID: 26113369, DOI: 10.1111/acem.12712.
- Swenson KE, Wira CR. Cause of an Elevated Lactate Level. JAMA 2015, 313: 2381. PMID: 26080348, DOI: 10.1001/jama.2015.5043.
- Asuzu D, Nystrom K, Amin H, Schindler J, Wira C, Greer D, Chi NF, Halliday J, Sheth KN. Comparison of 8 scores for predicting symptomatic intracerebral hemorrhage after IV thrombolysis. Neurocritical Care 2015, 22: 229-33. PMID: 25168743, DOI: 10.1007/s12028-014-0060-2.
- Asuzu D, Nystrom K, Amin H, Schindler J, Wira C, Greer D, Chi NF, Halliday J, Sheth KN. Modest association between the discharge modified Rankin Scale score and symptomatic intracerebral hemorrhage after intravenous thrombolysis. Journal Of Stroke And Cerebrovascular Diseases : The Official Journal Of National Stroke Association 2015, 24: 548-53. PMID: 25540072, DOI: 10.1016/j.jstrokecerebrovasdis.2014.09.034.
- Wira CR, Swenson K. Goal-Directed Therapy for Sepsis: Has the Beast Been Slain or Do Questions Remain? Connecticut Medicine 2015, 79: 97-9. PMID: 26244208.
- Madsen TE, Seigel TA, Mackenzie RS, Marcolini EG, Wira CR, Healy ME, Wright DW, Gentile NT. Gender differences in neurologic emergencies part I: a consensus summary and research agenda on cerebrovascular disease. Academic Emergency Medicine : Official Journal Of The Society For Academic Emergency Medicine 2014, 21: 1403-13. PMID: 25422086, DOI: 10.1111/acem.12528.
- Keegan J, Wira CR. Early identification and management of patients with severe sepsis and septic shock in the emergency department. Emergency Medicine Clinics Of North America 2014, 32: 759-76. PMID: 25441033, DOI: 10.1016/j.emc.2014.07.002.
- Wira CR, Dodge K, Sather J, Dziura J. Meta-analysis of protocolized goal-directed hemodynamic optimization for the management of severe sepsis and septic shock in the Emergency Department. The Western Journal Of Emergency Medicine 2014, 15: 51-9. PMID: 24696750, PMCID: PMC3952890, DOI: 10.5811/westjem.2013.7.6828.
- Wira CR, Francis MW, Bhat S, Ehrman R, Conner D, Siegel M. The shock index as a predictor of vasopressor use in emergency department patients with severe sepsis. The Western Journal Of Emergency Medicine 2014, 15: 60-6. PMID: 24696751, PMCID: PMC3952891, DOI: 10.5811/westjem.2013.7.18472.
- Lever NM, Nyström KV, Schindler JL, Halliday J, Wira C, Funk M. Missed opportunities for recognition of ischemic stroke in the emergency department. Journal Of Emergency Nursing: JEN : Official Publication Of The Emergency Department Nurses Association 2013, 39: 434-9. PMID: 22633790, DOI: 10.1016/j.jen.2012.02.011.
- Phipps MS, Desai RA, Wira C, Bravata DM. Epidemiology and outcomes of fever burden among patients with acute ischemic stroke. Stroke; A Journal Of Cerebral Circulation 2011, 42: 3357-62. PMID: 21980196, DOI: 10.1161/STROKEAHA.111.621425.
- Wira CR, Rivers E, Martinez-Capolino C, Silver B, Iyer G, Sherwin R, Lewandowski C. Cardiac complications in acute ischemic stroke. The Western Journal Of Emergency Medicine 2011, 12: 414-20. PMID: 22224130, PMCID: PMC3236132, DOI: 10.5811/westjem.2011.2.1765.
- Ehrman R, Wira C, Lomax A, Hayward A, Marcelin J, Ellis T, Przyklenk K, Volturo G, Mullen M. Etomidate use in severe sepsis and septic shock patients does not contribute to mortality. Internal And Emergency Medicine 2011, 6: 253-7. PMID: 21394520, DOI: 10.1007/s11739-011-0553-3.
- Wira CR, Rivers E, Silver B, Lewandowski C. The impact of cardiac contractility on cerebral blood flow in ischemia. The Western Journal Of Emergency Medicine 2011, 12: 227-32. PMID: 21691533, PMCID: PMC3099614.
- Becker JU, Theodosis C, Jacob ST, Wira CR, Groce NE. Surviving sepsis in low-income and middle-income countries: new directions for care and research. The Lancet. Infectious Diseases 2009, 9: 577-82. PMID: 19695494, DOI: 10.1016/S1473-3099(09)70135-5.
- Wira CR, Becker JU, Martin G, Donnino MW. Anti-arrhythmic and vasopressor medications for the treatment of ventricular fibrillation in severe hypothermia: a systematic review of the literature. Resuscitation 2008, 78: 21-9. PMID: 18406039, DOI: 10.1016/j.resuscitation.2008.01.025.
- Wira C, Sather J. Clinical risk stratification for gastrointestinal hemorrhage: still no consensus. Critical Care (London, England) 2008, 12: 154. PMID: 18533048, PMCID: PMC2481453, DOI: 10.1186/cc6900.
- Donnino MW, Miller J, Goyal N, Loomba M, Sankey SS, Dolcourt B, Sherwin R, Otero R, Wira C. Effective lactate clearance is associated with improved outcome in post-cardiac arrest patients. Resuscitation 2007, 75: 229-34. PMID: 17583412, DOI: 10.1016/j.resuscitation.2007.03.021.
- Wira C, Martin G, Stoner J, Margolis K, Donnino M. Application of normothermic cardiac arrest algorithms to hypothermic cardiac arrest in a canine model. Resuscitation 2006, 69: 509-16. PMID: 16597482, DOI: 10.1016/j.resuscitation.2005.10.028.
- Wira C, Lewandowski C, Silver B, Martinez-Capolino C, Rivers E. Correlation of Ejection Fraction with Transcranial Doppler Flow Rates in Patients with Acute Strokes. Western Journal of Emergency Medicine,(In Press).Wira C, Lewandowski C, Silver B, Martinez-Capolino C, Rivers E. Correlation of Ejection Fraction with Transcranial Doppler Flow Rates in Patients with Acute Strokes. Western Journal of Emergency Medicine,(In Press).
- Becker J, Wira C, Arnold J, Ischemic Stroke, September 5, 2006, EMedicine, www.emedicine.com.Becker J, Wira C, Arnold J, Ischemic Stroke, September 5, 2006, EMedicine, www.emedicine.com.
- Wira C, Rivers E, Donnino M, Shirazi E, Goyal N, Tomlanovich M. Surrogate Markers for Lactic Acidosis in Patients with Severe Sepsis and Septic Shock; Critical Care Medicine 2004, Vol. 32, No. 12 (Suppl.), p. A151.Wira C, Rivers E, Donnino M, Shirazi E, Goyal N, Tomlanovich M. Surrogate Markers for Lactic Acidosis in Patients with Severe Sepsis and Septic Shock; Critical Care Medicine 2004, Vol. 32, No. 12 (Suppl.), p. A151.
Patient Care Organizations
Titles
- Associate Professor Term
- Liaison, Yale-New Haven Stroke Program
Education & Training
- ResidentHenry Ford Hospital (2005)
- MDDartmouth School of Medicine (2000)
- BSUniversity of New Hampshire (1993)
Languages Spoken
- English
- Español (Spanish)
Additional Information
Honors & Recognitions
- Member, Stroke Council Leadership Committee: AHA/ASA (2020)
- Chair, Emergency Neurovascular Care Committee: AHA/ASA (2020)
- Chair: State of Connecticut Stroke Task Force (2016)
- Chair: NorthEast Cerebrovascular Consortium (NorthEast AHA/ASA) (2014)
- 2011 Residency Teacher of the Year--Yale DEM: Yale DEM Residents (2011)
- Co-Chair of the Acute Stroke Section: NECC/AHA/ASA
Board Certifications
- AB of Emergency Medicine, Emergency Medicine (2006, recertified: 2017)
Publications
- Rajendram P, Notario L, Reid C, Wira CR, Suarez JI, Weingart SD, Khosravani H. Crisis Resource Management and High-Performing Teams in Hyperacute Stroke Care. Neurocritical Care 2020, 33: 338-346. PMID: 32794144, PMCID: PMC7426067, DOI: 10.1007/s12028-020-01057-4.
- Jasne AS, Chojecka P, Maran I, Mageid R, Eldokmak M, Zhang Q, Nystrom K, Vlieks K, Askenase M, Petersen N, Falcone GJ, Wira CR, Lleva P, Zeevi N, Narula R, Amin H, Navaratnam D, Loomis C, Hwang DY, Schindler J, Hebert R, Matouk C, Krumholz HM, Spudich S, Sheth KN, Sansing LH, Sharma R. Stroke Code Presentations, Interventions, and Outcomes Before and During the COVID-19 Pandemic. Stroke; A Journal Of Cerebral Circulation 2020, 51: 2664-2673. PMID: 32755347, PMCID: PMC7446978, DOI: 10.1161/STR.0000000000000347.
- Wira CR, Goyal M, Southerland AM, Sheth KN, McNair ND, Khosravani H, Leonard A, Panagos P. Pandemic Guidance for Stroke Centers Aiding COVID-19 Treatment Teams. Stroke; A Journal Of Cerebral Circulation 2020, 51: 2587-2592. PMID: 32716826, PMCID: PMC7326321, DOI: 10.1161/STROKEAHA.120.030749.
- Goyal M, Ospel JM, Southerland AM, Wira C, Amin-Hanjani S, Fraser JF, Panagos P. Prehospital Triage of Acute Stroke Patients During the COVID-19 Pandemic. Stroke; A Journal Of Cerebral Circulation 2020, 51: 2263-2267. PMID: 32401680, DOI: 10.1161/STROKEAHA.120.030340.
- Liu RB, Bogucki S, Marcolini EG, Yu CY, Wira CR, Kalam S, Daley J, Moore CL, Cone DC. Guiding Cardiopulmonary Resuscitation with Focused Echocardiography: A Report of Five Cases. Prehospital Emergency Care : Official Journal Of The National Association Of EMS Physicians And The National Association Of State EMS Directors 2020, 24: 297-302. PMID: 31150302, DOI: 10.1080/10903127.2019.1626955.
- Wu X, Hughes DR, Gandhi D, Matouk CC, Sheth K, Schindler J, Wira C, Wintermark M, Sanelli P, Malhotra A. CT Angiography for Triage of Patients with Acute Minor Stroke: A Cost-effectiveness Analysis. Radiology 2020, 294: 580-588. PMID: 31934828, DOI: 10.1148/radiol.2019191238.
- Wira CR, Melluzzo S, Beasley TM, Magdon-Ismail Z, Day D, Madsen TE, McCullough LD, Stein J, Schwamm LH, Gropen T. Stroke Center Certification and Performance: A Longitudinal Analysis of the Northeast Cerebrovascular Consortium Region. The Yale Journal Of Biology And Medicine 2019, 92: 587-596. PMID: 31866774, PMCID: PMC6913814.
- Madsen TE, Wira CR. The Future of Minor Stroke and Transient Ischemic Attack: The RAVEN Approach Is Promising but Not Ready for Prime Time. Annals Of Emergency Medicine 2019, 74: 572-574. PMID: 31543123, DOI: 10.1016/j.annemergmed.2019.08.458.
- Belsky JB, Wira CR, Jacob V, Sather JE, Lee PJ. A review of micronutrients in sepsis: the role of thiamine, l-carnitine, vitamin C, selenium and vitamin D. Nutrition Research Reviews 2018, 31: 281-290. PMID: 29984680, DOI: 10.1017/S0954422418000124.
- Wira CR, Madsen TE, Chang BP, Nomura JT, Marcolini E, Gentile NT, Schreyer KE, Merck LH, Siket M, Greenberg K, Zammit CG, Jauch EC, Fernanda Bellolio M. Is There a Neurologist in the House? A Summary of the Current State of Neurovascular Rotations for Emergency Medicine Residents. AEM Education And Training 2018, 2: S56-S67. PMID: 30607380, PMCID: PMC6304277, DOI: 10.1002/aet2.10200.
- Swenson KE, Dziura JD, Aydin A, Reynolds J, Wira CR. Evaluation of a novel 5-group classification system of sepsis by vasopressor use and initial serum lactate in the emergency department. Internal And Emergency Medicine 2018, 13: 257-268. PMID: 28132131, DOI: 10.1007/s11739-017-1607-y.
- Chang BP, Wira C, Miller J, Akhter M, Barth BE, Willey J, Nentwich L, Madsen T. Neurology Concepts: Young Women and Ischemic Stroke-Evaluation and Management in the Emergency Department. Academic Emergency Medicine : Official Journal Of The Society For Academic Emergency Medicine 2018, 25: 54-64. PMID: 28646558, PMCID: PMC6415947, DOI: 10.1111/acem.13243.
- McGregor AJ, Beauchamp GA, Wira CR, Perman SM, Safdar B. Sex as a Biological Variable in Emergency Medicine Research and Clinical Practice: A Brief Narrative Review. The Western Journal Of Emergency Medicine 2017, 18: 1079-1090. PMID: 29085541, PMCID: PMC5654878, DOI: 10.5811/westjem.2017.8.34997.
- Miller JB, Lewandowski C, Wira CR, Taylor A, Burmeister C, Welch R. Volume of Plasma Expansion and Functional Outcomes in Stroke. Neurocritical Care 2017, 26: 191-195. PMID: 27629275, DOI: 10.1007/s12028-016-0316-0.
- Miller JB, Merck LH, Wira CR, Meurer WJ, Schrock JW, Nomura JT, Siket MS, Madsen TE, Wright DW, Panagos PD, Lewandowski C. The Advanced Reperfusion Era: Implications for Emergency Systems of Ischemic Stroke Care. Annals Of Emergency Medicine 2017, 69: 192-201. PMID: 27600649, DOI: 10.1016/j.annemergmed.2016.06.042.
- Giberson B, Uber A, F Gaieski D, Miller JB, Wira C, Berg K, Giberson T, Cocchi MN, S Abella B, Donnino MW. When to Stop CPR and When to Perform Rhythm Analysis: Potential Confusion Among ACLS Providers. Journal Of Intensive Care Medicine 2016, 31: 537-43. PMID: 25542192, DOI: 10.1177/0885066614561589.
- Wira CR, Swenson KE. Composition of the Sepsis Definitions Task Force. JAMA 2016, 316: 460. PMID: 27458964, DOI: 10.1001/jama.2016.6371.
- Asuzu D, Nystr¿m K, Amin H, Schindler J, Wira C, Greer D, Chi NF, Halliday J, Sheth KN. Validation of TURN, a simple predictor of symptomatic intracerebral hemorrhage after IV thrombolysis. Clinical Neurology And Neurosurgery 2016, 146: 71-5. PMID: 27152469, DOI: 10.1016/j.clineuro.2016.04.017.
- Asuzu D, Nyström K, Sreekrishnan A, Schindler J, Wira C, Greer D, Halliday J, Kimberly WT, Sheth KN. TURN Score Predicts 24-Hour Cerebral Edema After IV Thrombolysis. Neurocritical Care 2016, 24: 381-8. PMID: 26341364, DOI: 10.1007/s12028-015-0198-6.
- Arch AE, Weisman DC, Coca S, Nystrom KV, Wira CR, Schindler JL. Missed Ischemic Stroke Diagnosis in the Emergency Department by Emergency Medicine and Neurology Services. Stroke; A Journal Of Cerebral Circulation 2016, 47: 668-73. PMID: 26846858, DOI: 10.1161/STROKEAHA.115.010613.
- Asuzu D, Nystr¿m K, Schindler J, Wira C, Greer D, Halliday J, Sheth KN. Risk rtPA: An iOS mobile application based on TURN for predicting 90-day outcome after IV thrombolysis. Clinical Neurology And Neurosurgery 2016, 142: 148-152. PMID: 26875069, DOI: 10.1016/j.clineuro.2016.01.030.
- Asuzu D, Nystr¿m K, Amin H, Schindler J, Wira C, Greer D, Chi NF, Halliday J, Sheth KN. On- versus Off-Hour Patient Cohorts at a Primary Stroke Center: Onset-to-Treatment Duration and Clinical Outcomes after IV Thrombolysis. Journal Of Stroke And Cerebrovascular Diseases : The Official Journal Of National Stroke Association 2016, 25: 447-51. PMID: 26654664, DOI: 10.1016/j.jstrokecerebrovasdis.2015.10.017.
- Asuzu D, Nyström K, Amin H, Schindler J, Wira C, Greer D, Chi NF, Halliday J, Sheth KN. Cohort-Based Identification of Predictors of Symptomatic Intracerebral Hemorrhage After IV Thrombolysis. Neurocritical Care 2015, 23: 394-400. PMID: 25691004, DOI: 10.1007/s12028-015-0121-1.
- Bhat SR, Swenson KE, Francis MW, Wira CR. Lactate Clearance Predicts Survival Among Patients in the Emergency Department with Severe Sepsis. The Western Journal Of Emergency Medicine 2015, 16: 1118-26. PMID: 26759665, PMCID: PMC4703153, DOI: 10.5811/westjem.2015.10.27577.
- Asuzu D, Nyström K, Amin H, Schindler J, Wira C, Greer D, Chi NF, Halliday J, Sheth KN. TURN: A Simple Predictor of Symptomatic Intracerebral Hemorrhage After IV Thrombolysis. Neurocritical Care 2015, 23: 166-71. PMID: 25869481, DOI: 10.1007/s12028-015-0131-z.
- Asuzu D, Nyström K, Schindler J, Wira C, Greer D, Halliday J, Sheth KN. TURN Score Predicts 90-day Outcome in Acute Ischemic Stroke Patients After IV Thrombolysis. Neurocritical Care 2015, 23: 172-8. PMID: 26032809, DOI: 10.1007/s12028-015-0154-5.
- Sivaraju A, Gilmore EJ, Wira CR, Stevens A, Rampal N, Moeller JJ, Greer DM, Hirsch LJ, Gaspard N. Prognostication of post-cardiac arrest coma: early clinical and electroencephalographic predictors of outcome. Intensive Care Medicine 2015, 41: 1264-72. PMID: 25940963, DOI: 10.1007/s00134-015-3834-x.
- Miller JB, Heitsch L, Siket MS, Schrock JW, Wira CR, Lewandowski C, Madsen TE, Merck LH, Wright DW. The Emergency Medicine Debate on tPA for Stroke: What Is Best for Our Patients? Efficacy in the First Three Hours. Academic Emergency Medicine : Official Journal Of The Society For Academic Emergency Medicine 2015, 22: 852-5. PMID: 26113369, DOI: 10.1111/acem.12712.
- Swenson KE, Wira CR. Cause of an Elevated Lactate Level. JAMA 2015, 313: 2381. PMID: 26080348, DOI: 10.1001/jama.2015.5043.
- Asuzu D, Nystrom K, Amin H, Schindler J, Wira C, Greer D, Chi NF, Halliday J, Sheth KN. Comparison of 8 scores for predicting symptomatic intracerebral hemorrhage after IV thrombolysis. Neurocritical Care 2015, 22: 229-33. PMID: 25168743, DOI: 10.1007/s12028-014-0060-2.
- Asuzu D, Nystrom K, Amin H, Schindler J, Wira C, Greer D, Chi NF, Halliday J, Sheth KN. Modest association between the discharge modified Rankin Scale score and symptomatic intracerebral hemorrhage after intravenous thrombolysis. Journal Of Stroke And Cerebrovascular Diseases : The Official Journal Of National Stroke Association 2015, 24: 548-53. PMID: 25540072, DOI: 10.1016/j.jstrokecerebrovasdis.2014.09.034.
- Wira CR, Swenson K. Goal-Directed Therapy for Sepsis: Has the Beast Been Slain or Do Questions Remain? Connecticut Medicine 2015, 79: 97-9. PMID: 26244208.
- Madsen TE, Seigel TA, Mackenzie RS, Marcolini EG, Wira CR, Healy ME, Wright DW, Gentile NT. Gender differences in neurologic emergencies part I: a consensus summary and research agenda on cerebrovascular disease. Academic Emergency Medicine : Official Journal Of The Society For Academic Emergency Medicine 2014, 21: 1403-13. PMID: 25422086, DOI: 10.1111/acem.12528.
- Keegan J, Wira CR. Early identification and management of patients with severe sepsis and septic shock in the emergency department. Emergency Medicine Clinics Of North America 2014, 32: 759-76. PMID: 25441033, DOI: 10.1016/j.emc.2014.07.002.
- Wira CR, Dodge K, Sather J, Dziura J. Meta-analysis of protocolized goal-directed hemodynamic optimization for the management of severe sepsis and septic shock in the Emergency Department. The Western Journal Of Emergency Medicine 2014, 15: 51-9. PMID: 24696750, PMCID: PMC3952890, DOI: 10.5811/westjem.2013.7.6828.
- Wira CR, Francis MW, Bhat S, Ehrman R, Conner D, Siegel M. The shock index as a predictor of vasopressor use in emergency department patients with severe sepsis. The Western Journal Of Emergency Medicine 2014, 15: 60-6. PMID: 24696751, PMCID: PMC3952891, DOI: 10.5811/westjem.2013.7.18472.
- Lever NM, Nyström KV, Schindler JL, Halliday J, Wira C, Funk M. Missed opportunities for recognition of ischemic stroke in the emergency department. Journal Of Emergency Nursing: JEN : Official Publication Of The Emergency Department Nurses Association 2013, 39: 434-9. PMID: 22633790, DOI: 10.1016/j.jen.2012.02.011.
- Phipps MS, Desai RA, Wira C, Bravata DM. Epidemiology and outcomes of fever burden among patients with acute ischemic stroke. Stroke; A Journal Of Cerebral Circulation 2011, 42: 3357-62. PMID: 21980196, DOI: 10.1161/STROKEAHA.111.621425.
- Wira CR, Rivers E, Martinez-Capolino C, Silver B, Iyer G, Sherwin R, Lewandowski C. Cardiac complications in acute ischemic stroke. The Western Journal Of Emergency Medicine 2011, 12: 414-20. PMID: 22224130, PMCID: PMC3236132, DOI: 10.5811/westjem.2011.2.1765.
- Ehrman R, Wira C, Lomax A, Hayward A, Marcelin J, Ellis T, Przyklenk K, Volturo G, Mullen M. Etomidate use in severe sepsis and septic shock patients does not contribute to mortality. Internal And Emergency Medicine 2011, 6: 253-7. PMID: 21394520, DOI: 10.1007/s11739-011-0553-3.
- Wira CR, Rivers E, Silver B, Lewandowski C. The impact of cardiac contractility on cerebral blood flow in ischemia. The Western Journal Of Emergency Medicine 2011, 12: 227-32. PMID: 21691533, PMCID: PMC3099614.
- Becker JU, Theodosis C, Jacob ST, Wira CR, Groce NE. Surviving sepsis in low-income and middle-income countries: new directions for care and research. The Lancet. Infectious Diseases 2009, 9: 577-82. PMID: 19695494, DOI: 10.1016/S1473-3099(09)70135-5.
- Wira CR, Becker JU, Martin G, Donnino MW. Anti-arrhythmic and vasopressor medications for the treatment of ventricular fibrillation in severe hypothermia: a systematic review of the literature. Resuscitation 2008, 78: 21-9. PMID: 18406039, DOI: 10.1016/j.resuscitation.2008.01.025.
- Wira C, Sather J. Clinical risk stratification for gastrointestinal hemorrhage: still no consensus. Critical Care (London, England) 2008, 12: 154. PMID: 18533048, PMCID: PMC2481453, DOI: 10.1186/cc6900.
- Donnino MW, Miller J, Goyal N, Loomba M, Sankey SS, Dolcourt B, Sherwin R, Otero R, Wira C. Effective lactate clearance is associated with improved outcome in post-cardiac arrest patients. Resuscitation 2007, 75: 229-34. PMID: 17583412, DOI: 10.1016/j.resuscitation.2007.03.021.
- Wira C, Martin G, Stoner J, Margolis K, Donnino M. Application of normothermic cardiac arrest algorithms to hypothermic cardiac arrest in a canine model. Resuscitation 2006, 69: 509-16. PMID: 16597482, DOI: 10.1016/j.resuscitation.2005.10.028.
- Wira C, Lewandowski C, Silver B, Martinez-Capolino C, Rivers E. Correlation of Ejection Fraction with Transcranial Doppler Flow Rates in Patients with Acute Strokes. Western Journal of Emergency Medicine,(In Press).Wira C, Lewandowski C, Silver B, Martinez-Capolino C, Rivers E. Correlation of Ejection Fraction with Transcranial Doppler Flow Rates in Patients with Acute Strokes. Western Journal of Emergency Medicine,(In Press).
- Becker J, Wira C, Arnold J, Ischemic Stroke, September 5, 2006, EMedicine, www.emedicine.com.Becker J, Wira C, Arnold J, Ischemic Stroke, September 5, 2006, EMedicine, www.emedicine.com.
- Wira C, Rivers E, Donnino M, Shirazi E, Goyal N, Tomlanovich M. Surrogate Markers for Lactic Acidosis in Patients with Severe Sepsis and Septic Shock; Critical Care Medicine 2004, Vol. 32, No. 12 (Suppl.), p. A151.Wira C, Rivers E, Donnino M, Shirazi E, Goyal N, Tomlanovich M. Surrogate Markers for Lactic Acidosis in Patients with Severe Sepsis and Septic Shock; Critical Care Medicine 2004, Vol. 32, No. 12 (Suppl.), p. A151.
Patient Care Organizations
1
Yale Emergency Medicine
Yale New Haven Hospital
20 York Street, Ste South Pavilion Suite 218
New Haven, CT 06510
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- Yale Emergency MedicineYale New Haven Hospital20 York Street, Ste South Pavilion Suite 218New Haven, CT 06510
- Yale Emergency MedicineYale New Haven Shoreline Medical Center111 Goose LaneGuilford, CT 06437