Carolyn Fredericks, MD
Memory Disorders & Cognitive Neurology, Neurology
Patient type treated
Adult
Accepting new patients
Yes
Referral required
From physicians only
Board Certified in
Neurology and Behavioral Neurology & Neuropsychiatry
Titles
- Assistant Professor
Education & Training
- FellowMemory and Aging Center, University of California, San Francisco (2016)
- ResidentUniversity of California, San Francisco (2014)
- ResidentJohns Hopkins Hospital (2012)
- InternStanford University Hospital (2011)
- MDStanford University School of Medicine (2010)
- BABrown University, Classics (2004)
- BSBrown University, Neuroscience (2004)
Additional Information
Board Certifications
- United Council for Neurologic Subspecialties, Behavioral Neurology & Neuropsychiatry (2018)
- AB of Psychiatry & Neurology, Neurology (2014)
Publications
- Napolioni V, Fredericks CA, Kim Y, Channappa D, Khan RR, Kim LH, Zafar F, Couthouis J, Davidzon GA, Mormino EC, Gitler AD, Montine TJ, Schüle B, Greicius MD. Phenotypic Heterogeneity among GBA p.R202X Carriers in Lewy Body Spectrum Disorders. Biomedicines 2022, 10 PMID: 35052839, PMCID: PMC8774039, DOI: 10.3390/biomedicines10010160.
- Fredericks C. Methylphenidate for Apathy in Alzheimer Disease-Why Should We Care? JAMA Neurology 2021, 78: 1311-1313. PMID: 34570178, DOI: 10.1001/jamaneurol.2021.2942.
- Mormino EC, Toueg TN, Azevedo C, Castillo JB, Guo W, Nadiadwala A, Corso NK, Hall JN, Fan A, Trelle AN, Harrison MB, Hunt MP, Sha SJ, Deutsch G, James M, Fredericks CA, Koran ME, Zeineh M, Poston K, Greicius MD, Khalighi M, Davidzon GA, Shen B, Zaharchuk G, Wagner AD, Chin FT. Tau PET imaging with 18F-PI-2620 in aging and neurodegenerative diseases. European Journal Of Nuclear Medicine And Molecular Imaging 2021, 48: 2233-2244. PMID: 32572562, PMCID: PMC7755737, DOI: 10.1007/s00259-020-04923-7.
- Trelle AN, Carr VA, Wilson EN, Swarovski MS, Hunt MP, Toueg TN, Tran TT, Channappa D, Corso NK, Thieu MK, Jayakumar M, Nadiadwala A, Guo W, Tanner NJ, Bernstein JD, Litovsky CP, Guerin SA, Khazenzon AM, Harrison MB, Rutt BK, Deutsch GK, Chin FT, Davidzon GA, Hall JN, Sha SJ, Fredericks CA, Andreasson KI, Kerchner GA, Wagner AD, Mormino EC. Association of CSF Biomarkers With Hippocampal-Dependent Memory in Preclinical Alzheimer Disease. Neurology 2021, 96: e1470-e1481. PMID: 33408146, PMCID: PMC8055319, DOI: 10.1212/WNL.0000000000011477.
- Trelle AN, Carr VA, Guerin SA, Thieu MK, Jayakumar M, Guo W, Nadiadwala A, Corso NK, Hunt MP, Litovsky CP, Tanner NJ, Deutsch GK, Bernstein JD, Harrison MB, Khazenzon AM, Jiang J, Sha SJ, Fredericks CA, Rutt BK, Mormino EC, Kerchner GA, Wagner AD. Hippocampal and cortical mechanisms at retrieval explain variability in episodic remembering in older adults. ELife 2020, 9 PMID: 32469308, PMCID: PMC7259949, DOI: 10.7554/eLife.55335.
- Pressman PS, Gola K, Shdo SM, Miller BL, Fredericks C, Mielke C, Pelak V, Rankin KP. Relative preservation of facial expression recognition in posterior cortical atrophy. Neurology 2019, 92: e1064-e1071. PMID: 30760634, PMCID: PMC6442010, DOI: 10.1212/WNL.0000000000007075.
- Fredericks CA, Brown JA, Deng J, Kramer A, Ossenkoppele R, Rankin K, Kramer JH, Miller BL, Rabinovici GD, Seeley WW. Intrinsic connectivity networks in posterior cortical atrophy: A role for the pulvinar? NeuroImage. Clinical 2019, 21: 101628. PMID: 30528957, PMCID: PMC6411779, DOI: 10.1016/j.nicl.2018.101628.
- Fredericks CA, Sturm VE, Brown JA, Hua AY, Bilgel M, Wong DF, Resnick SM, Seeley WW. Early affective changes and increased connectivity in preclinical Alzheimer's disease. Alzheimer's & Dementia (Amsterdam, Netherlands) 2018, 10: 471-479. PMID: 30302368, PMCID: PMC6174255, DOI: 10.1016/j.dadm.2018.06.002.
- Fredericks CA, Koestler M, Seeley W, Miller B, Boxer A, Grinberg LT. Primary chronic traumatic encephalopathy in an older patient with late-onset AD phenotype. Neurology. Clinical Practice 2015, 5: 475-479. PMID: 26716062, PMCID: PMC4684670, DOI: 10.1212/CPJ.0000000000000161.
- Burish MJ, Fredericks CA, Engstrom JW, Tateo VL, Josephson SA. Predicting success: What medical student measures predict resident performance in neurology? Clinical Neurology And Neurosurgery 2015, 135: 69-72. PMID: 26038279, DOI: 10.1016/j.clineuro.2015.05.007.
- Fredericks CA, Kvam KA, Bear J, Crabtree GS, Josephson SA. A case of progressive multifocal leukoencephalopathy in a lupus patient treated with belimumab. Lupus 2014, 23: 711-3. PMID: 24531080, DOI: 10.1177/0961203314524292.
- Blond BN, Fredericks CA, Blumberg HP. Functional neuroanatomy of bipolar disorder: structure, function, and connectivity in an amygdala-anterior paralimbic neural system. Bipolar Disorders 2012, 14: 340-55. PMID: 22631619, PMCID: PMC3880745, DOI: 10.1111/j.1399-5618.2012.01015.x.
- Fredericks CA, Drabant EM, Edge MD, Tillie JM, Hallmayer J, Ramel W, Kuo JR, Mackey S, Gross JJ, Dhabhar FS. Healthy young women with serotonin transporter SS polymorphism show a pro-inflammatory bias under resting and stress conditions. Brain, Behavior, And Immunity 2010, 24: 350-7. PMID: 19883751, PMCID: PMC2826575, DOI: 10.1016/j.bbi.2009.10.014.
- Chepenik LG, Fredericks C, Papademetris X, Spencer L, Lacadie C, Wang F, Pittman B, Duncan JS, Staib LH, Duman RS, Gelernter J, Blumberg HP. Effects of the brain-derived neurotrophic growth factor val66met variation on hippocampus morphology in bipolar disorder. Neuropsychopharmacology : Official Publication Of The American College Of Neuropsychopharmacology 2009, 34: 944-51. PMID: 18704093, PMCID: PMC2837582, DOI: 10.1038/npp.2008.107.
- Blumberg HP, Fredericks C, Wang F, Kalmar JH, Spencer L, Papademetris X, Pittman B, Martin A, Peterson BS, Fulbright RK, Krystal JH. Preliminary evidence for persistent abnormalities in amygdala volumes in adolescents and young adults with bipolar disorder. Bipolar Disorders 2005, 7: 570-6. PMID: 16403182, PMCID: PMC2291299, DOI: 10.1111/j.1399-5618.2005.00264.x.
- Blumberg HP, Leung HC, Skudlarski P, Lacadie CM, Fredericks CA, Harris BC, Charney DS, Gore JC, Krystal JH, Peterson BS. A functional magnetic resonance imaging study of bipolar disorder: state- and trait-related dysfunction in ventral prefrontal cortices. Archives Of General Psychiatry 2003, 60: 601-9. PMID: 12796223, DOI: 10.1001/archpsyc.60.6.601.
Patient Care Organizations
Titles
- Assistant Professor
Education & Training
- FellowMemory and Aging Center, University of California, San Francisco (2016)
- ResidentUniversity of California, San Francisco (2014)
- ResidentJohns Hopkins Hospital (2012)
- InternStanford University Hospital (2011)
- MDStanford University School of Medicine (2010)
- BABrown University, Classics (2004)
- BSBrown University, Neuroscience (2004)
Additional Information
Board Certifications
- United Council for Neurologic Subspecialties, Behavioral Neurology & Neuropsychiatry (2018)
- AB of Psychiatry & Neurology, Neurology (2014)
Publications
- Napolioni V, Fredericks CA, Kim Y, Channappa D, Khan RR, Kim LH, Zafar F, Couthouis J, Davidzon GA, Mormino EC, Gitler AD, Montine TJ, Schüle B, Greicius MD. Phenotypic Heterogeneity among GBA p.R202X Carriers in Lewy Body Spectrum Disorders. Biomedicines 2022, 10 PMID: 35052839, PMCID: PMC8774039, DOI: 10.3390/biomedicines10010160.
- Fredericks C. Methylphenidate for Apathy in Alzheimer Disease-Why Should We Care? JAMA Neurology 2021, 78: 1311-1313. PMID: 34570178, DOI: 10.1001/jamaneurol.2021.2942.
- Mormino EC, Toueg TN, Azevedo C, Castillo JB, Guo W, Nadiadwala A, Corso NK, Hall JN, Fan A, Trelle AN, Harrison MB, Hunt MP, Sha SJ, Deutsch G, James M, Fredericks CA, Koran ME, Zeineh M, Poston K, Greicius MD, Khalighi M, Davidzon GA, Shen B, Zaharchuk G, Wagner AD, Chin FT. Tau PET imaging with 18F-PI-2620 in aging and neurodegenerative diseases. European Journal Of Nuclear Medicine And Molecular Imaging 2021, 48: 2233-2244. PMID: 32572562, PMCID: PMC7755737, DOI: 10.1007/s00259-020-04923-7.
- Trelle AN, Carr VA, Wilson EN, Swarovski MS, Hunt MP, Toueg TN, Tran TT, Channappa D, Corso NK, Thieu MK, Jayakumar M, Nadiadwala A, Guo W, Tanner NJ, Bernstein JD, Litovsky CP, Guerin SA, Khazenzon AM, Harrison MB, Rutt BK, Deutsch GK, Chin FT, Davidzon GA, Hall JN, Sha SJ, Fredericks CA, Andreasson KI, Kerchner GA, Wagner AD, Mormino EC. Association of CSF Biomarkers With Hippocampal-Dependent Memory in Preclinical Alzheimer Disease. Neurology 2021, 96: e1470-e1481. PMID: 33408146, PMCID: PMC8055319, DOI: 10.1212/WNL.0000000000011477.
- Trelle AN, Carr VA, Guerin SA, Thieu MK, Jayakumar M, Guo W, Nadiadwala A, Corso NK, Hunt MP, Litovsky CP, Tanner NJ, Deutsch GK, Bernstein JD, Harrison MB, Khazenzon AM, Jiang J, Sha SJ, Fredericks CA, Rutt BK, Mormino EC, Kerchner GA, Wagner AD. Hippocampal and cortical mechanisms at retrieval explain variability in episodic remembering in older adults. ELife 2020, 9 PMID: 32469308, PMCID: PMC7259949, DOI: 10.7554/eLife.55335.
- Pressman PS, Gola K, Shdo SM, Miller BL, Fredericks C, Mielke C, Pelak V, Rankin KP. Relative preservation of facial expression recognition in posterior cortical atrophy. Neurology 2019, 92: e1064-e1071. PMID: 30760634, PMCID: PMC6442010, DOI: 10.1212/WNL.0000000000007075.
- Fredericks CA, Brown JA, Deng J, Kramer A, Ossenkoppele R, Rankin K, Kramer JH, Miller BL, Rabinovici GD, Seeley WW. Intrinsic connectivity networks in posterior cortical atrophy: A role for the pulvinar? NeuroImage. Clinical 2019, 21: 101628. PMID: 30528957, PMCID: PMC6411779, DOI: 10.1016/j.nicl.2018.101628.
- Fredericks CA, Sturm VE, Brown JA, Hua AY, Bilgel M, Wong DF, Resnick SM, Seeley WW. Early affective changes and increased connectivity in preclinical Alzheimer's disease. Alzheimer's & Dementia (Amsterdam, Netherlands) 2018, 10: 471-479. PMID: 30302368, PMCID: PMC6174255, DOI: 10.1016/j.dadm.2018.06.002.
- Fredericks CA, Koestler M, Seeley W, Miller B, Boxer A, Grinberg LT. Primary chronic traumatic encephalopathy in an older patient with late-onset AD phenotype. Neurology. Clinical Practice 2015, 5: 475-479. PMID: 26716062, PMCID: PMC4684670, DOI: 10.1212/CPJ.0000000000000161.
- Burish MJ, Fredericks CA, Engstrom JW, Tateo VL, Josephson SA. Predicting success: What medical student measures predict resident performance in neurology? Clinical Neurology And Neurosurgery 2015, 135: 69-72. PMID: 26038279, DOI: 10.1016/j.clineuro.2015.05.007.
- Fredericks CA, Kvam KA, Bear J, Crabtree GS, Josephson SA. A case of progressive multifocal leukoencephalopathy in a lupus patient treated with belimumab. Lupus 2014, 23: 711-3. PMID: 24531080, DOI: 10.1177/0961203314524292.
- Blond BN, Fredericks CA, Blumberg HP. Functional neuroanatomy of bipolar disorder: structure, function, and connectivity in an amygdala-anterior paralimbic neural system. Bipolar Disorders 2012, 14: 340-55. PMID: 22631619, PMCID: PMC3880745, DOI: 10.1111/j.1399-5618.2012.01015.x.
- Fredericks CA, Drabant EM, Edge MD, Tillie JM, Hallmayer J, Ramel W, Kuo JR, Mackey S, Gross JJ, Dhabhar FS. Healthy young women with serotonin transporter SS polymorphism show a pro-inflammatory bias under resting and stress conditions. Brain, Behavior, And Immunity 2010, 24: 350-7. PMID: 19883751, PMCID: PMC2826575, DOI: 10.1016/j.bbi.2009.10.014.
- Chepenik LG, Fredericks C, Papademetris X, Spencer L, Lacadie C, Wang F, Pittman B, Duncan JS, Staib LH, Duman RS, Gelernter J, Blumberg HP. Effects of the brain-derived neurotrophic growth factor val66met variation on hippocampus morphology in bipolar disorder. Neuropsychopharmacology : Official Publication Of The American College Of Neuropsychopharmacology 2009, 34: 944-51. PMID: 18704093, PMCID: PMC2837582, DOI: 10.1038/npp.2008.107.
- Blumberg HP, Fredericks C, Wang F, Kalmar JH, Spencer L, Papademetris X, Pittman B, Martin A, Peterson BS, Fulbright RK, Krystal JH. Preliminary evidence for persistent abnormalities in amygdala volumes in adolescents and young adults with bipolar disorder. Bipolar Disorders 2005, 7: 570-6. PMID: 16403182, PMCID: PMC2291299, DOI: 10.1111/j.1399-5618.2005.00264.x.
- Blumberg HP, Leung HC, Skudlarski P, Lacadie CM, Fredericks CA, Harris BC, Charney DS, Gore JC, Krystal JH, Peterson BS. A functional magnetic resonance imaging study of bipolar disorder: state- and trait-related dysfunction in ventral prefrontal cortices. Archives Of General Psychiatry 2003, 60: 601-9. PMID: 12796223, DOI: 10.1001/archpsyc.60.6.601.
Patient Care Organizations