Our nationally ranked team of caregivers are experts in diagnosing and managing a broad range of acute and chronic kidney diseases, both in the inpatient and outpatient settings. We offer around-the-clock primary care to patients with established renal disease or hypertension, and our physicians are readily available for consultation on newly referred patients. Our services are comprehensive. In some cases, we consult and collaborate with other doctors and work hand-in-hand with referring providers. In other circumstances, we are principal caregivers for our patients. In nearly all instances, our care is multidisciplinary, involving other physicians and specialists, nurse practitioners, physician associates, and skilled nurses. We are committed to: Being available 24/7 to our patients and referring physicians Open communication with patients, families and referring physicians Applying new approaches to treating and diagnosing renal diseases and their complications Advocating for our patients We offer: A dedicated nephrology floor at Yale New Haven Hospital A large outpatient peritoneal dialysis practice and home hemodialysis practice Clinical trials on the cutting edge of polycystic kidney disease (PKD) that attract patients from surrounding areas and states. Weekend seminars for patients with PKD and inherited kidney disease Dedicated subspecialty services for inherited kidney diseases, hypertension, cardio-renal syndrome, onco-nephrology, and kidney disease in pregnancy Our special services include evaluating and caring for patients with: Acute kidney injury Cardiovascular dysautonomia (e.g., orthostatic hypotension) Chronic kidney disease Diabetic kidney disease Dialysis therapies Electrolyte and/or acid-base disorders Glomerular diseases/Glomerulonephritis Hypertension Inherited kidney diseases Kidney disease and hypertension in pregnancy Kidney disease in cancer Kidney disease in heart failure Kidney transplantation Nephrolithiasis Polycystic kidney disease Largest—and rapidly expanding—kidney transplant program in New England with multidisciplinary care clinics Inherited kidney disease program, with coordinated access to multidisciplinary care for extra-renal disease, advanced genetic testing, and counseling Joint nephrology/urology kidney stone program for management of complex nephrolithiasis Multidisciplinary hypertension program for advanced diagnostic evaluation and management of complex hypertension and cardiovascular dysautonomia Advanced chronic kidney disease and end-stage renal disease program Dedicated nephrology floor at Yale New Haven Hospital Clinical trials and innovative research protocols in polycystic kidney disease, acute kidney injury, diabetic kidney disease, anemia in kidney disease, and peritoneal dialysis

At Laboratory Medicine, we study the molecular and cellular components of blood and other body fluids. This work is crucial to diagnosing and managing illness and understanding the mechanisms and origins of disease.Our physicians, known as clinical pathologists, provide consultations to other doctors regarding optimal laboratory diagnostic approaches and the interpretation of complex laboratory tests. Our team includes pathologists, scientists, phlebotomists, medical technicians, technologists, and others who perform important support functions for our state-of-the-art laboratory. We are available every day, 24 hours a day, for physicians. We perform approximately 10 million tests each year, and also provide specialized high-tech testing to other hospitals in the Yale New Haven Health System and institutions throughout New England, and as far away as Puerto Rico. We also operate multiple satellite facilities and patient service centers located throughout the state. We ensure that every test we offer—at every location—is accurate and reliable. When physicians request to have patients’ blood drawn, here is what happens: Collection: A doctor, nurse, technician, or phlebotomist will draw the patient’s blood. Several tubes may be needed for different types of tests. Depending on what illness the patient might have, his or her doctor may want to obtain a urine sample, throat swab, or other sample. After the sample is collected, the container is labeled with the patient’s name and other information. The sample is received and processed by the Laboratory, and testing begins: Chemistry Testing Blood and other bodily fluids are tested for chemicals, drugs, and substances that indicate disease. We check cholesterol and other tests for risk of heart disease, glucose to monitor diabetes, or thyroxin to monitor the thyroid gland. Hematology Testing We analyze the amount and function of blood cells and plasma. Examples include the Complete Blood Count (CBC) that tells the doctor how many cells of each type are in the patient’s blood, and the prothrombin time (PT) to measure the time it takes for the blood to clot. Microbiology Testing We test a variety of specimen samples for infections caused by bacteria, fungi, or parasites. We often do urine cultures for urinary tract infections. Virology Testing We test for viral infections. This includes rapid tests for respiratory viruses such as influenza, molecular tests for noroviruses, and antibody tests for HIV. Immunology/Molecular Diagnostics Some tests are used to determine whether the immune system is functioning properly. State-of-the-art analysis of DNA and RNA is used to test for a variety of diseases and for the risk of developing certain diseases. Other specialized tests include the ANA, used to screen for autoimmune disease, and Factor V Leiden genotyping for patients with blood clots. Tumor Profiling Laboratory This lab analyzes tumor DNA to predict the sensitivity or resistance of tumors to a

Polycystic kidney disease (PKD) causes fluid-filled sacs called cysts to grow in the kidneys. The cysts can become large and cause scarring, eventually harming the organs’ function. This disease is caused by a gene mutation, usually passed down by a parent. Polycystic kidney disease is typically diagnosed using imaging studies, such as ultrasound, which will show the cysts in the kidneys. A genetic test performed on a blood or saliva sample can detect the gene mutations that cause the disease. The Yale Medicine Polycystic Kidney Disease Program, recognized as a Center of Excellence by the PKD Foundation, offers patients the opportunity to receive care from experts who can explain the nuances of inherited disorders to patients and skillfully manage the illness. Yale Medicine offers opportunities for patients with polycystic kidney disease to take part in clinical trials, which aim to help doctors better understand the disease and evaluate new treatment approaches. The experts at Yale Medicine are also at the forefront of basic research into the mechanisms underlying cyst formation. By seamlessly combining clinical expertise with research engagement, we provide patients with the best care and knowledge the PKD field has to offer.