Blood Clot
Definition
A blood clot is a semi-solid mass formed by the coagulation of blood components, primarily platelets and fibrin, which can occur within a blood vessel or at the site of an injury. Blood clots can be beneficial in preventing excessive bleeding but may also cause complications if they obstruct blood flow or dislodge and travel to other parts of the body.
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Hematology Program
The Hematology Program at Smilow Cancer Hospital offers comprehensive diagnosis and treatment of blood cancers: lymphoma, leukemia, and myeloma. While the causes of these cancers remain unknown, great strides in treatment, some of which originated from Yale Cancer Center research, are improving survival rates. The overall aim of treatment is to bring about a complete remission. Treatment approaches for blood cancers may include chemotherapy, radiation oncology, stem cell or marrow transplantation, or immunotherapy. Each patient receives an individual treatment plan, which includes standard care and/or clinical trials, which offer novel treatment options. Yale hematopathologists employ the complete range of diagnostic tools available, including bone marrow examination, bone imaging, M protein analysis, cytogenetics, immunophenotyping, and FISH and PCR analysis, as well as genetic testing and the identification of markers that guide prognosis. Additionally, patients have access to caregivers who help them cope with the physical, emotional, and psychological issues related to these cancers. Advanced practice nurses and social workers assist with education, general information, and practical issues of travel and accommodation assistance. The blood cancers we are fighting: Lymphoma is the most common blood cancer, affecting 81,000 Americans each year. While its rates continue to rise, there have also been rapid advances in treatment, and the current 5-year survival rate for all people diagnosed with Hodgkin lymphoma is 87%. Leukemia is a malignant cancer of the bone marrow and blood, diagnosed in 60,000 Americans each year. It is the most common cancer in children and teens. The leukemia death rate for children ranging from birth to age 14 in the United States has declined 60% over the past three decades, due to treatment advances. Myeloma is a disease of the plasma cell, and affects approximately 34,000 new patients annually. Overall survival in patients with myeloma has shown improvement in recent years, with treatments recently approved by the Food and Drug Administration (FDA). Monoclonal gammopathy of undetermined significance (MGUS) is a precursor condition that could potentially lead to cancer and should be closely evaluated and monitored. Our myeloma specialists are dedicated to the care of these patients and see them as part of a MGUS Clinic. Stem Cell Transplant The Stem Cell Transplant Program at Smilow Cancer Hospital is a FACT accredited program that was started in 1994 and currently performs around 200 transplants yearly. We perform stem cell and bone marrow transplants for a variety of malignant and benign diseases in both pediatric and adult populations. There are two types of stem cell transplantation that we perform: Autologous transplant: involves using a patient’s own stem cells, whichare collected from their blood and frozen. Allogeneic transplant: involves receiving stem cells from another person, called a donor. A searchVascular Surgery & Endovascular Therapy
At Yale Medicine, our team of highly trained vascular surgeons are here to help with a variety of circulation issues. This includes anything from blocked blood vessels and stubborn wounds to conditions that could lead to losing a limb. Our goal is to give complete care that's as easy on you as possible, which is why we focus on techniques that don't require major surgery, like treatments done inside the blood vessels themselves. Our doctors give personalized and complete care to adults with vascular problems. We rely on the newest and most advanced equipment and methods to diagnose and treat these conditions. Specialized care is offered in the following areas: Abdominal and thoracic aortic aneurysm: Bulges in the main artery that can occur in the belly or chest area. Aortoiliac occlusive disease: Blocked arteries that supply blood to the abdomen, pelvis, and legs. Carotid artery stenosis: Narrowed arteries in the neck that can reduce blood flow to the brain. Claudication: Treatments to help relieve cramping in the legs while walking or exercising Diabetic ulcers: Sores that are slow to heal in people with diabetes. Dialysis access: For patients who need dialysis (a treatment for kidney failure), we create an entry point into the bloodstream that the dialysis machine can use. Foot ulcers: Sores on the feet that can develop due to poor circulation or other health issue. Lower extremity artery conditions Lower extremity vein conditions Renal vascular disease: Conditions that affect blood flow to the kidneys. Thoracic aortic aneurysm and aortic dissection: Bulges and tears in the part of the main artery that runs through the chest. Thoracic outlet syndrome: Discomfort or circulation problems caused when blood vessels or nerves just below the neck are compressed. Varicose veins: Treatments to remove or reduce enlarged veins that appear most often on the legs. Visceral artery disease: Blood vessels that supply the internal organs, ensuring they're not narrowed or blocked.Preventive Cardiovascular Health Program
The Preventive Cardiovascular Health Program at Yale (PCHPY) brings a personalized approach to cardiovascular disease prevention. Patients referred to the program meet with one of our cardiologists for an in-depth consultation that takes into account their biology and biography, along with information from advanced diagnostic testing. This approach leads to a more personalized, evidence-based approach to cardiovascular risk assessment. Using this information, and in partnership with patients, we design tailored programs to reduce cardiovascular risk and improve well-being. PCHPY brings together experts in cardiovascular disease prevention, including cardiologists, nutritionists, exercise physiologists and health psychologists. We also work together with Digital Technology Solutions (Information Technology) and digital health companies to offer high-tech/low-burden approaches to cardiovascular care. Our team is highly attuned to the challenges of maintaining a healthy lifestyle and taking medication, and understands that a one-size-fits all approach often falls short. Instead, we strive to understand and integrate each person’ priorities, preferences and goals into the care plan. This program is particularly focused on people who are: At increased risk for cardiovascular disease, including people with: Severe hypercholesterolemia or familial hypercholesterolemia or elevated Lp(a) Family history of premature coronary artery disease (before the age of 60) Poorly controlled hypertension Underlying inflammatory condition (e.g., rheumatoid arthritis, HIV) A diagnosis of ischemic heart disease or coronary artery disease Women with cardiovascular disease Individuals seeking a more personalized approach to cardiovascular health PCHPY additionally works with communities to identify and address barriers to cardiovascular health, focusing on environmental and social factors that contribute to disparities in health outcomes.