Shamsuddin Akhtar, MD
Anesthesiology, Critical Care Medicine
Biography
Shamsuddin Akhtar, MD, is an anesthesiologist and critical care specialist who focuses on providing safe and effective anesthesia for patients undergoing surgery and those who require care in the intensive care unit. Much of his work centers on ensuring that elderly patients receive carefully adjusted doses of anesthesia to reduce complications such as low blood pressure.
As professor of anesthesiology and pharmacology at Yale School of Medicine, Dr. Akhtar conducts research aimed at refining anesthesia techniques for older patients, and he has authored a textbook on geriatric critical care. He also values mentorship and is committed to educating the next generation of medical professionals. “The mentorship of students, trainees, and junior faculty is something that I particularly enjoy and is a fulfilling aspect of my career,” he says.
He completed his medical training at Aga Khan University, followed by an internship in internal medicine and a residency in anesthesiology at SUNY at Stony Brook. He pursued a fellowship in critical care anesthesiology at the Medical College of Wisconsin and an additional fellowship in major vascular and thoracic anesthesia at Yale School of Medicine.
Titles
- Professor of Anesthesiology and Pharmacology
- Medical Director of YNHH 7-1 Surgical Intensive Care Unit
Education & Training
- FellowYale University School of Medicine (1998)
- FellowMedical College of Wisconsin (1996)
- ResidentSUNY at Stony Brook (1995)
- InternSUNY at Stony Brook (1992)
- MDAga Khan University (1989)
Languages Spoken
- English
- ਪੰਜਾਬੀ (Punjabi)
- اردو (Urdu)
Additional Information
Board Certifications
- AB of Anesthesiology, Critical Care Medicine (Anesthesiology) (1997)
Publications
- Neuman MD, Feng R, Ellenberg SS, Sieber F, Sessler DI, Magaziner J, Elkassabany N, Schwenk ES, Dillane D, Marcantonio ER, Menio D, Ayad S, Hassan M, Stone T, Papp S, Donegan D, Marshall M, Jaffe JD, Luke C, Sharma B, Azim S, Hymes R, Chin KJ, Sheppard R, Perlman B, Sappenfield J, Hauck E, Hoeft MA, Tierney A, Gaskins LJ, Horan AD, Brown T, Dattilo J, Carson JL, Looke T, Bent S, Franco-Mora A, Hedrick P, Newbern M, Tadros R, Pealer K, Vlassakov K, Buckley C, Gavin L, Gorbatov S, Gosnell J, Steen T, Vafai A, Zeballos J, Hruslinski J, Cardenas L, Berry A, Getchell J, Quercetti N, Bajracharya G, Billow D, Bloomfield M, Cuko E, Elyaderani MK, Hampton R, Honar H, Khoshknabi D, Kim D, Krahe D, Lew MM, Maheshwer CB, Niazi A, Saha P, Salih A, de Swart RJ, Volio A, Bolkus K, DeAngelis M, Dodson G, Gerritsen J, McEniry B, Mitrev L, Kwofie MK, Belliveau A, Bonazza F, Lloyd V, Panek I, Dabiri J, Chavez C, Craig J, Davidson T, Dietrichs C, Fleetwood C, Foley M, Getto C, Hailes S, Hermes S, Hooper A, Koener G, Kohls K, Law L, Lipp A, Losey A, Nelson W, Nieto M, Rogers P, Rutman S, Scales G, Sebastian B, Stanciu T, Lobel G, Giampiccolo M, Herman D, Kaufman M, Murphy B, Pau C, Puzio T, Veselsky M, Apostle K, Boyer D, Fan BC, Lee S, Lemke M, Merchant R, Moola F, Payne K, Perey B, Viskontas D, Poler M, D'Antonio P, O'Neill G, Abdullah A, Fish-Fuhrmann J, Giska M, Fidkowski C, Guthrie ST, Hakeos W, Hayes L, Hoegler J, Nowak K, Beck J, Cuff J, Gaski G, Haaser S, Holzman M, Malekzadeh AS, Ramsey L, Schulman J, Schwartzbach C, Azefor T, Davani A, Jaberi M, Masear C, Haider SB, Chungu C, Ebrahimi A, Fikry K, Marcantonio A, Shelvan A, Sanders D, Clarke C, Lawendy A, Schwartz G, Garg M, Kim J, Caruci J, Commeh E, Cuevas R, Cuff G, Franco L, Furgiuele D, Giuca M, Allman M, Barzideh O, Cossaro J, D'Arduini A, Farhi A, Gould J, Kafel J, Patel A, Peller A, Reshef H, Safur M, Toscano F, Tedore T, Akerman M, Brumberger E, Clark S, Friedlander R, Jegarl A, Lane J, Lyden JP, Mehta N, Murrell MT, Painter N, Ricci W, Sbrollini K, Sharma R, Steel PAD, Steinkamp M, Weinberg R, Wellman DS, Nader A, Fitzgerald P, Ritz M, Bryson G, Craig A, Farhat C, Gammon B, Gofton W, Harris N, Lalonde K, Liew A, Meulenkamp B, Sonnenburg K, Wai E, Wilkin G, Troxell K, Alderfer ME, Brannen J, Cupitt C, Gerhart S, McLin R, Sheidy J, Yurick K, Chen F, Dragert K, Kiss G, Malveaux H, McCloskey D, Mellender S, Mungekar SS, Noveck H, Sagebien C, Biby L, McKelvy G, Richards A, Abola R, Ayala B, Halper D, Mavarez A, Rizwan S, Choi S, Awad I, Flynn B, Henry P, Jenkinson R, Kaustov L, Lappin E, McHardy P, Singh A, Donnelly J, Gonzalez M, Haydel C, Livelsberger J, Pazionis T, Slattery B, Vazquez-Trejo M, Baratta J, Cirullo M, Deiling B, Deschamps L, Glick M, Katz D, Krieg J, Lessin J, Mojica J, Torjman M, Jin R, Salpeter MJ, Powell M, Simmons J, Lawson P, Kukreja P, Graves S, Sturdivant A, Bryant A, Crump SJ, Verrier M, Green J, Menon M, Applegate R, Arias A, Pineiro N, Uppington J, Wolinsky P, Gunnett A, Hagen J, Harris S, Hollen K, Holloway B, Horodyski MB, Pogue T, Ramani R, Smith C, Woods A, Warrick M, Flynn K, Mongan P, Ranganath Y, Fernholz S, Ingersoll-Weng E, Marian A, Seering M, Sibenaller Z, Stout L, Wagner A, Walter A, Wong C, Orwig D, Goud M, Helker C, Mezenghie L, Montgomery B, Preston P, Schwartz JS, Weber R, Fleisher LA, Mehta S, Stephens-Shields AJ, Dinh C, Chelly JE, Goel S, Goncz W, Kawabe T, Khetarpal S, Monroe A, Shick V, Breidenstein M, Dominick T, Friend A, Mathews D, Lennertz R, Sanders R, Akere H, Balweg T, Bo A, Doro C, Goodspeed D, Lang G, Parker M, Rettammel A, Roth M, White M, Whiting P, Allen BFS, Baker T, Craven D, McEvoy M, Turnbo T, Kates S, Morgan M, Willoughby T, Weigel W, Auyong D, Fox E, Welsh T, Cusson B, Dobson S, Edwards C, Harris L, Henshaw D, Johnson K, McKinney G, Miller S, Reynolds J, Segal BS, Turner J, VanEenenaam D, Weller R, Lei J, Treggiari M, Akhtar S, Blessing M, Johnson C, Kampp M, Kunze K, O'Connor M, Looke T, Tadros R, Vlassakov K, Cardenas L, Bolkus K, Mitrev L, Kwofie MK, Dabiri J, Lobel G, Poler M, Giska M, Sanders D, Schwartz G, Giuca M, Tedore T, Nader A, Bryson G, Troxell K, Kiss G, Choi S, Powell M, Applegate R, Warrick M, Ranganath Y, Chelly JE, Lennertz R, Sanders R, Allen BFS, Kates S, Weigel W, Li J, Wijeysundera DN, Kheterpal S, Moore RH, Smith AK, Tosi LL, Looke T, Mehta S, Fleisher L, Hruslinski J, Ramsey L, Langlois C, Mezenghie L, Montgomery B, Oduwole S, Rose T. Pain, Analgesic Use, and Patient Satisfaction With Spinal Versus General Anesthesia for Hip Fracture Surgery : A Randomized Clinical Trial. Annals Of Internal Medicine 2022, 175: 952-960. PMID: 35696684, DOI: 10.7326/M22-0320.
- Bardia A, Akhtar S, Schonberger RB. Response to comment on: “Association of propofol induction dose and severe pre-incision hypotension among surgical patients over age 65”. Journal Of Clinical Anesthesia 2022, 81: 110911. PMID: 35780644, PMCID: PMC11146281, DOI: 10.1016/j.jclinane.2022.110911.
- Ammar MA, Ammar AA, Wee T, Deshpande R, Band M, Akhtar S. Relationship Between Glucose Time in Range in Diabetic and Non-Diabetic Patients and Mortality in Critically Ill Patients. Journal Of Intensive Care Medicine 2022, 37: 1625-1633. PMID: 35491687, DOI: 10.1177/08850666221098383.
- Schonberger RB, Dai F, Michel G, Vaughn MT, Burg MM, Mathis M, Kheterpal S, Akhtar S, Shah N, Bardia A. Association of propofol induction dose and severe pre-incision hypotension among surgical patients over age 65. Journal Of Clinical Anesthesia 2022, 80: 110846. PMID: 35489305, PMCID: PMC11150018, DOI: 10.1016/j.jclinane.2022.110846.
- Raredon MSB, Fisher C, Heerdt PM, Schonberger RB, Nargi A, Nivison S, Fajardo E, Deshpande R, Akhtar S, Greaney AM, Belter J, Raredon T, Zinter J, McKee A, Michalski M, Baevova P, Niklason LE. Pressure-Regulated Ventilator Splitting for Disaster Relief: Design, Testing, and Clinical Experience. Anesthesia & Analgesia 2021, 134: 1094-1105. PMID: 34928890, DOI: 10.1213/ane.0000000000005825.
- Akhtar S. Preoperative evaluation of geriatric patients undergoing liver transplantation. Current Opinion In Anaesthesiology 2021, 35: 96-104. PMID: 34878418, DOI: 10.1097/aco.0000000000001084.
- Akhtar S. Neurological Aging and Pharmacological Management of Geriatric Patients. Current Anesthesiology Reports 2021, 11: 381-386. DOI: 10.1007/s40140-021-00497-8.
- Ammar M, Ammar A, Cheung C, Akhtar S. Pharmacological Adjuncts to Palliation in the Trauma Patient: Optimal Symptom Management. Current Trauma Reports 2021, 7: 73-82. DOI: 10.1007/s40719-021-00215-z.
- Akhtar S, Bardia A, Schonberger RB. Reply to: Comment on: Variation in propofol induction doses administered to surgical patients over 65. Journal Of The American Geriatrics Society 2021, 69: 2680-2681. PMID: 34185888, PMCID: PMC8440365, DOI: 10.1111/jgs.17327.
- Schonberger RB, Bardia A, Dai F, Michel G, Yanez D, Curtis JP, Vaughn MT, Burg MM, Mathis M, Kheterpal S, Akhtar S, Shah N. Variation in propofol induction doses administered to surgical patients over age 65. Journal Of The American Geriatrics Society 2021, 69: 2195-2209. PMID: 33788251, PMCID: PMC8373684, DOI: 10.1111/jgs.17139.
- Lumas S, Hsiang W, Akhtar S, Ochoa Chaar CI. Regional Anesthesia is Underutilized for Carotid Endarterectomy Despite Improved Perioperative Outcomes Compared with General Anesthesia. Annals Of Vascular Surgery 2020, 73: 336-343. PMID: 33373769, DOI: 10.1016/j.avsg.2020.11.035.
- Chen EY, Michel G, Zhou B, Dai F, Akhtar S, Schonberger RB. An Analysis of Anesthesia Induction Dosing in Female Older Adults. Drugs & Aging 2020, 37: 435-446. PMID: 32300966, PMCID: PMC7359723, DOI: 10.1007/s40266-020-00760-3.
- Ammar M, Ammar A, Deshpande R, Band M, Akhtar S. 321: RELATIONSHIP BETWEEN GLUCOSE TIME IN RANGE IN DIABETIC AND NONDIABETIC PATIENTS AND MORTALITY. Critical Care Medicine 2020, 48: 143-143. DOI: 10.1097/01.ccm.0000619640.00502.9a.
- Tao J, Bukanova EN, Akhtar S. Safety of 4-factor prothrombin complex concentrate (4F-PCC) for emergent reversal of factor Xa inhibitors. Journal Of Intensive Care 2018, 6: 34. PMID: 29942519, PMCID: PMC6001072, DOI: 10.1186/s40560-018-0303-y.
- Akhtar S. Perioperative Outcome in Geriatric Patients. Current Anesthesiology Reports 2018, 8: 232-237. DOI: 10.1007/s40140-018-0267-4.
- Akhtar S. Pharmacological considerations in the elderly. Current Opinion In Anaesthesiology 2018, 31: 11-18. PMID: 29189287, DOI: 10.1097/aco.0000000000000544.
- Freudzon L, Akhtar S, London M, Barash P, Badescu G, Sherman B, Zaidan J. Chapter 9 Electrocardiographic Monitoring. 2018, 168-202. DOI: 10.1016/b978-0-323-49798-5.00009-7.
- Tantawy H, Li A, Dai F, Elgammal M, Sukumar N, Elefteriades J, Akhtar S. Association of red blood cell transfusion and short- and longer-term mortality after coronary artery bypass graft surgery. Journal Of Cardiothoracic And Vascular Anesthesia 2017, 32: 1225-1232. PMID: 29402623, DOI: 10.1053/j.jvca.2017.12.033.
- Akhtar S, Ebert T. Cardiovascular System. 2017, 161-178. DOI: 10.1007/978-3-319-66878-9_11.
- Akhtar S. Hemophilia. 2017, 327-332. DOI: 10.1007/978-3-319-50141-3_42.
- Chen EY, Sukumar N, Dai F, Akhtar S, Schonberger RB. A Pilot Analysis of the Association Between Types of Monitored Anesthesia Care Drugs and Outcomes in Transfemoral Aortic Valve Replacement Performed Without General Anesthesia. Journal Of Cardiothoracic And Vascular Anesthesia 2017, 32: 666-671. PMID: 29277298, PMCID: PMC5766429, DOI: 10.1053/j.jvca.2017.07.009.
- Akhtar S, Heng J, Dai F, Schonberger RB, Burg MM. A Retrospective Observational Study of Anesthetic Induction Dosing Practices in Female Elderly Surgical Patients: Are We Overdosing Older Patients? Drugs & Aging 2016, 33: 737-746. PMID: 27581549, DOI: 10.1007/s40266-016-0394-x.
- Akhtar S, Liu J, Heng J, Dai F, Schonberger RB, Burg MM. Does intravenous induction dosing among patients undergoing gastrointestinal surgical procedures follow current recommendations: a study of contemporary practice. Journal Of Clinical Anesthesia 2016, 33: 208-215. PMID: 27555166, DOI: 10.1016/j.jclinane.2016.02.001.
- Akhtar S. Erratum to Case 3—2015 Preventing Adverse Outcomes in the Very Elderly Cardiac Surgical Patients J Cardiothorac Vasc Anesth 29(2015):510-521. Journal Of Cardiothoracic And Vascular Anesthesia 2015, 29: e37. DOI: 10.1053/j.jvca.2015.04.026.
- Akhtar S, Ramani R. Geriatric Pharmacology. Anesthesiology Clinics 2015, 33: 457-469. PMID: 26315631, DOI: 10.1016/j.anclin.2015.05.004.
- Akhtar S, Morris B, Roy R, Balogun SA. Case 3–2015 Preventing Adverse Outcomes in the Very Elderly Cardiac Surgical Patients. Journal Of Cardiothoracic And Vascular Anesthesia 2014, 29: 510-521. PMID: 25440648, DOI: 10.1053/j.jvca.2014.07.014.
- Akhtar S. Kidney Injury After Vascular Surgery. 2014, 125-134. DOI: 10.1007/978-1-4939-1273-5_10.
- Deshpande R, Akhtar S, Haddadin AS. Utility of ultrasound in the ICU. Current Opinion In Anaesthesiology 2014, 27: 123-132. PMID: 24589673, DOI: 10.1097/aco.0000000000000057.
- Akhtar S, Rooke G. Cardiovascular ageing. 2014, 41-52. DOI: 10.1093/med/9780199604999.003.0006.
- Heng J, Akhtar S. Increased Hypotension Due to Age-Uncorrected Anesthetic Dosing in the Elderly: A Single Institutional Study. CHEST Journal 2014, 145: 188a-1-188a-2. DOI: 10.1378/chest.1835524.
- Akhtar S. Guidelines and Perioperative Care of the Elderly. International Anesthesiology Clinics 2014, 52: 64-76. PMID: 25268865, DOI: 10.1097/aia.0000000000000033.
- Akhtar S. Vascular Surgery: Endovascular and Major Vascular Surgery. 2012, 235-253. DOI: 10.1007/978-1-4614-3888-5_16.
- Akhtar S. Chapter 13 Diseases of the Endocrine System. 2012, 401-432. DOI: 10.1016/b978-1-4377-2787-6.00013-9.
- Alexanian SM, McDonnell ME, Akhtar S. Creating a Perioperative Glycemic Control Program. Anesthesiology Research And Practice 2011, 2011: 465974. PMID: 21912542, PMCID: PMC3168770, DOI: 10.1155/2011/465974.
- Maerz LL, Akhtar S. Perioperative glycemic management in 2011. Current Opinion In Critical Care 2011, 17: 370-375. PMID: 21734491, DOI: 10.1097/mcc.0b013e328348beb7.
- Akhtar S, Matei V, London M, Barash P. 15 Electrocardiographic Monitoring. 2011, 452-465. DOI: 10.1016/b978-1-4377-1617-7.00017-0.
- Akhtar S. Diabetic Ketoacidosis (DKA). 2011, 122. DOI: 10.1016/b978-1-4377-1720-4.00109-6.
- Akhtar S, Rappa R, Ghori M. Pain Management in Elderly Patients. 2010, 699-713. DOI: 10.1007/978-0-387-87579-8_32.
- Barash P, Akhtar S. Coronary stents: factors contributing to perioperative major adverse cardiovascular events. British Journal Of Anaesthesia 2010, 105: i3-i15. PMID: 21148653, DOI: 10.1093/bja/aeq318.
- Mirchandani A, Akhtar S. Pain pathways and pain processing. 2010, 7-12. DOI: 10.1017/cbo9780511841378.003.
- Conlin F, Akhtar S. Overview of adrenergic and serotoninergic pain suppression. 2010, 328-329. DOI: 10.1017/cbo9780511841378.080.
- Peterfreund RA, Akhtar S. How Sweet It Is … (or Isn’t)! Anesthesia & Analgesia 2010, 110: 979-981. PMID: 20357141, DOI: 10.1213/ane.0b013e3181d4527e.
- Akhtar S, Barash PG, Inzucchi SE. Scientific Principles and Clinical Implications of Perioperative Glucose Regulation and Control. Anesthesia & Analgesia 2010, 110: 478-497. PMID: 20081134, DOI: 10.1213/ane.0b013e3181c6be63.
- Akhtar S. Fat Embolism. Anesthesiology Clinics 2009, 27: 533-550. PMID: 19825491, DOI: 10.1016/j.anclin.2009.07.018.
- Akhtar S, Podgoreanu M, Harrison B, Brull S. Effect of lidocaine on endothelin-1-mediated airway smooth muscle contraction in the rat trachea. Minerva Anestesiologica 2008, 74: 643-50. PMID: 18971893.
- Akhtar S, Assaad, Amin M, Holt NF, Barash PG, Silverman DG. Preoperative β-blocker use: impact of national guidelines on clinical practice. Journal Of Clinical Anesthesia 2008, 20: 122-128. PMID: 18410867, DOI: 10.1016/j.jclinane.2007.09.012.
- Akhtar S. CHAPTER 1 Ischemic Heart Disease. 2008, 1-25. DOI: 10.1016/b978-1-4160-3998-3.10001-6.
- Tantawy H, Silverman TJ, Silverman DG, Akhtar S. Survey of anesthesiologists as to the value of prior ECG in a patient with nonspecific ST-T wave changes. Connecticut Medicine 2007, 71: 453-6. PMID: 17902381.
- Akhtar S. Pulmonary Physiology Review. 2007, 23-44. DOI: 10.3109/9781420016840-3.
- Akhtar S. Pulmonary Physiology Review. 2007, 868-889. DOI: 10.1201/b16040-46.
- Ranjbaran H, Sokol SI, Gallo A, Eid RE, Iakimov AO, D’Alessio A, Kapoor JR, Akhtar S, Howes CJ, Aslan M, Pfau S, Pober JS, Tellides G. An Inflammatory Pathway of IFN-γ Production in Coronary Atherosclerosis. The Journal Of Immunology 2007, 178: 592-604. PMID: 17182600, DOI: 10.4049/jimmunol.178.1.592.
- Akhtar S. Ischemic Heart Disease. Anesthesiology Clinics 2006, 24: 461-485. PMID: 17240602, DOI: 10.1016/j.atc.2006.04.002.
- Ranjbaran H, Wang Y, Manes TD, Yakimov AO, Akhtar S, Kluger MS, Pober JS, Tellides G. Heparin Displaces Interferon-γ–Inducible Chemokines (IP-10, I-TAC, and Mig) Sequestered in the Vasculature and Inhibits the Transendothelial Migration and Arterial Recruitment of T Cells. Circulation 2006, 114: 1293-1300. PMID: 16940188, DOI: 10.1161/circulationaha.106.631457.
- Martinez EA, Nass CM, Jermyn RM, Rosenbaum SH, Akhtar S, Chan DW, Malkus H, Weiss JL, Fleisher LA. Intermittent Cardiac Troponin-I Screening is an Effective Means of Surveillance for a Perioperative Myocardial Infarction. Journal Of Cardiothoracic And Vascular Anesthesia 2005, 19: 577-582. PMID: 16202889, DOI: 10.1053/j.jvca.2005.07.002.
- Akhtar S, Amin M, Tantawy H, Senior A, Barash PG, Silverman DG. Preoperative β-blocker use: is titration to a heart rate of 60 beats per minute a consistently attainable goal? Journal Of Clinical Anesthesia 2005, 17: 191-197. PMID: 15896586, DOI: 10.1016/j.jclinane.2004.06.020.
- Silverman D, Akhtar S. DES, Not Always the Best! Critical Care Medicine 2004, 32: 2166. DOI: 10.1097/01.ccm.0000139632.93986.0d.
- Akhtar S, Silverman DG. Assessment and management of patients with ischemic heart disease. Critical Care Medicine 2004, 32: s126-s136. PMID: 15064671, DOI: 10.1097/01.ccm.0000121576.73871.2d.
- Akhtar S. Biomarkers and perioperative myocardial infarction. Journal Of Critical Care 2003, 22: 50-61. DOI: 10.1016/s0277-0326(02)00002-8.
- Akhtar S, Silverman D, Senior A, Manning C, Barash P. Pre-Operative Beta-Blocker Use in High Risk Patients: Is There Room for Improvement? Anesthesiology 2002, 96: a224. DOI: 10.1097/00000542-200209002-00224.
- Akhtar S, Barash PG. Significance of beta‐blockers in the perioperative period. Current Opinion In Anaesthesiology 2002, 15: 27. PMID: 17019181, DOI: 10.1097/00001503-200202000-00005.
- Akhtar S, Barash PG. Perioperative Use of Beta-Blockers: Past, Present, and Future. International Anesthesiology Clinics 2002, 40: 133-157. PMID: 11897941, DOI: 10.1097/00004311-200204000-00012.
- Akhtar S, Podgoreanu M. PDGF-Induced DNA Synthesis in Human Lung Fibroblast is Inhibited by Lidocaine. Anesthesiology 2001, 2001: b25. DOI: 10.1097/00000542-200109001-00025.
- Akhtar S, Fleisher L, Jermyn R, Chan D, Rosenbaum S. Room 302, 10/18/2000 9: 00 AM - 10: 30 AM (PD) Detection of Perioperative Ischemia is Improved by Troponin (TnI) Measurement. Anesthesiology 2000, 93: a-253. DOI: 10.1097/00000542-200009001-00253.
- Akhtar S, Fleisher L, Jermyn R, Weiss J, Rosenbaum S. Room 302, 10/18/2000 9: 00 AM - 10: 30 AM (PD) Incidence of Perioperative Myocardial Injury Based on ACC/ AHA Guidelines in Vascular Surgery Patients. Anesthesiology 2000, 93: a-260. DOI: 10.1097/00000542-200009001-00260.
- Akhtar S, EghbaliWebb M. Room A, 10/16/2000 9: 00 AM - 11: 00 AM (PS) Effect of Lidocaine on DNA Synthesis in Human Lung Fibroblasts. Anesthesiology 2000, 93: a-813. DOI: 10.1097/00000542-200009001-00813.
- Akhtar S, Weigle C, Cheng E, Toohill R, Berens R. Use of active noise cancellation devices in caregivers in the intensive care unit. Critical Care Medicine 2000, 28: 1157-1160. PMID: 10809298, DOI: 10.1097/00003246-200004000-00040.
- Akhtar S. Con: Preoperative thallium testing should not be performed routinely before vascular surgery. Journal Of Cardiothoracic And Vascular Anesthesia 2000, 14: 221-223. PMID: 10794348, DOI: 10.1016/s1053-0770(00)90024-7.
- RABY K, BRULL S, TIMIMI F, AKHTAR S, ROSENBAUM S, NAIMI C, WHITTEMORE A. The Effect of Heart Rate Control on Myocardial Ischemia Among High-Risk Patients After Vascular Surgery. Survey Of Anesthesiology 2000, 44: 10. DOI: 10.1097/00132586-200002000-00010.
- Akhtar S, Brull S. INTRAOPERATIVE USE OF ANTICOAGULANTS AND ANTITHROMBOTICS Heparin and Beyond. Anesthesiology Clinics 1999, 17: 831-860. DOI: 10.1016/s0889-8537(05)70136-x.
- Akhtar S, Mazzeo A, Cheng E, Bosnjak Z, Kampine J. Differential bronchodilatory effects of terbutaline, diltiazem, and aminophylline in canine intraparenchymal airways. Critical Care Medicine 1999, 27: 1551-1556.. PMID: 10470763, DOI: 10.1097/00003246-199908000-00024.
- Raby K, Brull S, Timimi F, Akhtar S, Rosenbaum S, Naimi C, Whittemore A. The effect of heart rate control on myocardial ischemia among high-risk patients after vascular surgery. Anesthesia & Analgesia 1999, 88: 477-82. PMID: 10071990, DOI: 10.1097/00000539-199903000-00002.
- Raby K, Brull S, Timimi F, Akhtar S, Rosenbaum S, Naimi C, Whittemore A. The Effect of Heart Rate Control on Myocardial Ischemia Among High-Risk Patients After Vascular Surgery. Anesthesia & Analgesia 1999, 88: 477-482.. DOI: 10.1213/00000539-199903000-00002.
- Akhtar S, Silverman D, Brull S. EFFECTS OF LIDOCAINE ON ENDOTHELIN-1 INDUCED CONSTRICTION IN RAT TRACHEA. Anesthesia & Analgesia 1998, 86: 424s.. DOI: 10.1097/00000539-199802001-00422.
Departments and Programs
Biography
Shamsuddin Akhtar, MD, is an anesthesiologist and critical care specialist who focuses on providing safe and effective anesthesia for patients undergoing surgery and those who require care in the intensive care unit. Much of his work centers on ensuring that elderly patients receive carefully adjusted doses of anesthesia to reduce complications such as low blood pressure.
As professor of anesthesiology and pharmacology at Yale School of Medicine, Dr. Akhtar conducts research aimed at refining anesthesia techniques for older patients, and he has authored a textbook on geriatric critical care. He also values mentorship and is committed to educating the next generation of medical professionals. “The mentorship of students, trainees, and junior faculty is something that I particularly enjoy and is a fulfilling aspect of my career,” he says.
He completed his medical training at Aga Khan University, followed by an internship in internal medicine and a residency in anesthesiology at SUNY at Stony Brook. He pursued a fellowship in critical care anesthesiology at the Medical College of Wisconsin and an additional fellowship in major vascular and thoracic anesthesia at Yale School of Medicine.
Titles
- Professor of Anesthesiology and Pharmacology
- Medical Director of YNHH 7-1 Surgical Intensive Care Unit
Education & Training
- FellowYale University School of Medicine (1998)
- FellowMedical College of Wisconsin (1996)
- ResidentSUNY at Stony Brook (1995)
- InternSUNY at Stony Brook (1992)
- MDAga Khan University (1989)
Languages Spoken
- English
- ਪੰਜਾਬੀ (Punjabi)
- اردو (Urdu)
Additional Information
Board Certifications
- AB of Anesthesiology, Critical Care Medicine (Anesthesiology) (1997)
Publications
- Neuman MD, Feng R, Ellenberg SS, Sieber F, Sessler DI, Magaziner J, Elkassabany N, Schwenk ES, Dillane D, Marcantonio ER, Menio D, Ayad S, Hassan M, Stone T, Papp S, Donegan D, Marshall M, Jaffe JD, Luke C, Sharma B, Azim S, Hymes R, Chin KJ, Sheppard R, Perlman B, Sappenfield J, Hauck E, Hoeft MA, Tierney A, Gaskins LJ, Horan AD, Brown T, Dattilo J, Carson JL, Looke T, Bent S, Franco-Mora A, Hedrick P, Newbern M, Tadros R, Pealer K, Vlassakov K, Buckley C, Gavin L, Gorbatov S, Gosnell J, Steen T, Vafai A, Zeballos J, Hruslinski J, Cardenas L, Berry A, Getchell J, Quercetti N, Bajracharya G, Billow D, Bloomfield M, Cuko E, Elyaderani MK, Hampton R, Honar H, Khoshknabi D, Kim D, Krahe D, Lew MM, Maheshwer CB, Niazi A, Saha P, Salih A, de Swart RJ, Volio A, Bolkus K, DeAngelis M, Dodson G, Gerritsen J, McEniry B, Mitrev L, Kwofie MK, Belliveau A, Bonazza F, Lloyd V, Panek I, Dabiri J, Chavez C, Craig J, Davidson T, Dietrichs C, Fleetwood C, Foley M, Getto C, Hailes S, Hermes S, Hooper A, Koener G, Kohls K, Law L, Lipp A, Losey A, Nelson W, Nieto M, Rogers P, Rutman S, Scales G, Sebastian B, Stanciu T, Lobel G, Giampiccolo M, Herman D, Kaufman M, Murphy B, Pau C, Puzio T, Veselsky M, Apostle K, Boyer D, Fan BC, Lee S, Lemke M, Merchant R, Moola F, Payne K, Perey B, Viskontas D, Poler M, D'Antonio P, O'Neill G, Abdullah A, Fish-Fuhrmann J, Giska M, Fidkowski C, Guthrie ST, Hakeos W, Hayes L, Hoegler J, Nowak K, Beck J, Cuff J, Gaski G, Haaser S, Holzman M, Malekzadeh AS, Ramsey L, Schulman J, Schwartzbach C, Azefor T, Davani A, Jaberi M, Masear C, Haider SB, Chungu C, Ebrahimi A, Fikry K, Marcantonio A, Shelvan A, Sanders D, Clarke C, Lawendy A, Schwartz G, Garg M, Kim J, Caruci J, Commeh E, Cuevas R, Cuff G, Franco L, Furgiuele D, Giuca M, Allman M, Barzideh O, Cossaro J, D'Arduini A, Farhi A, Gould J, Kafel J, Patel A, Peller A, Reshef H, Safur M, Toscano F, Tedore T, Akerman M, Brumberger E, Clark S, Friedlander R, Jegarl A, Lane J, Lyden JP, Mehta N, Murrell MT, Painter N, Ricci W, Sbrollini K, Sharma R, Steel PAD, Steinkamp M, Weinberg R, Wellman DS, Nader A, Fitzgerald P, Ritz M, Bryson G, Craig A, Farhat C, Gammon B, Gofton W, Harris N, Lalonde K, Liew A, Meulenkamp B, Sonnenburg K, Wai E, Wilkin G, Troxell K, Alderfer ME, Brannen J, Cupitt C, Gerhart S, McLin R, Sheidy J, Yurick K, Chen F, Dragert K, Kiss G, Malveaux H, McCloskey D, Mellender S, Mungekar SS, Noveck H, Sagebien C, Biby L, McKelvy G, Richards A, Abola R, Ayala B, Halper D, Mavarez A, Rizwan S, Choi S, Awad I, Flynn B, Henry P, Jenkinson R, Kaustov L, Lappin E, McHardy P, Singh A, Donnelly J, Gonzalez M, Haydel C, Livelsberger J, Pazionis T, Slattery B, Vazquez-Trejo M, Baratta J, Cirullo M, Deiling B, Deschamps L, Glick M, Katz D, Krieg J, Lessin J, Mojica J, Torjman M, Jin R, Salpeter MJ, Powell M, Simmons J, Lawson P, Kukreja P, Graves S, Sturdivant A, Bryant A, Crump SJ, Verrier M, Green J, Menon M, Applegate R, Arias A, Pineiro N, Uppington J, Wolinsky P, Gunnett A, Hagen J, Harris S, Hollen K, Holloway B, Horodyski MB, Pogue T, Ramani R, Smith C, Woods A, Warrick M, Flynn K, Mongan P, Ranganath Y, Fernholz S, Ingersoll-Weng E, Marian A, Seering M, Sibenaller Z, Stout L, Wagner A, Walter A, Wong C, Orwig D, Goud M, Helker C, Mezenghie L, Montgomery B, Preston P, Schwartz JS, Weber R, Fleisher LA, Mehta S, Stephens-Shields AJ, Dinh C, Chelly JE, Goel S, Goncz W, Kawabe T, Khetarpal S, Monroe A, Shick V, Breidenstein M, Dominick T, Friend A, Mathews D, Lennertz R, Sanders R, Akere H, Balweg T, Bo A, Doro C, Goodspeed D, Lang G, Parker M, Rettammel A, Roth M, White M, Whiting P, Allen BFS, Baker T, Craven D, McEvoy M, Turnbo T, Kates S, Morgan M, Willoughby T, Weigel W, Auyong D, Fox E, Welsh T, Cusson B, Dobson S, Edwards C, Harris L, Henshaw D, Johnson K, McKinney G, Miller S, Reynolds J, Segal BS, Turner J, VanEenenaam D, Weller R, Lei J, Treggiari M, Akhtar S, Blessing M, Johnson C, Kampp M, Kunze K, O'Connor M, Looke T, Tadros R, Vlassakov K, Cardenas L, Bolkus K, Mitrev L, Kwofie MK, Dabiri J, Lobel G, Poler M, Giska M, Sanders D, Schwartz G, Giuca M, Tedore T, Nader A, Bryson G, Troxell K, Kiss G, Choi S, Powell M, Applegate R, Warrick M, Ranganath Y, Chelly JE, Lennertz R, Sanders R, Allen BFS, Kates S, Weigel W, Li J, Wijeysundera DN, Kheterpal S, Moore RH, Smith AK, Tosi LL, Looke T, Mehta S, Fleisher L, Hruslinski J, Ramsey L, Langlois C, Mezenghie L, Montgomery B, Oduwole S, Rose T. Pain, Analgesic Use, and Patient Satisfaction With Spinal Versus General Anesthesia for Hip Fracture Surgery : A Randomized Clinical Trial. Annals Of Internal Medicine 2022, 175: 952-960. PMID: 35696684, DOI: 10.7326/M22-0320.
- Bardia A, Akhtar S, Schonberger RB. Response to comment on: “Association of propofol induction dose and severe pre-incision hypotension among surgical patients over age 65”. Journal Of Clinical Anesthesia 2022, 81: 110911. PMID: 35780644, PMCID: PMC11146281, DOI: 10.1016/j.jclinane.2022.110911.
- Ammar MA, Ammar AA, Wee T, Deshpande R, Band M, Akhtar S. Relationship Between Glucose Time in Range in Diabetic and Non-Diabetic Patients and Mortality in Critically Ill Patients. Journal Of Intensive Care Medicine 2022, 37: 1625-1633. PMID: 35491687, DOI: 10.1177/08850666221098383.
- Schonberger RB, Dai F, Michel G, Vaughn MT, Burg MM, Mathis M, Kheterpal S, Akhtar S, Shah N, Bardia A. Association of propofol induction dose and severe pre-incision hypotension among surgical patients over age 65. Journal Of Clinical Anesthesia 2022, 80: 110846. PMID: 35489305, PMCID: PMC11150018, DOI: 10.1016/j.jclinane.2022.110846.
- Raredon MSB, Fisher C, Heerdt PM, Schonberger RB, Nargi A, Nivison S, Fajardo E, Deshpande R, Akhtar S, Greaney AM, Belter J, Raredon T, Zinter J, McKee A, Michalski M, Baevova P, Niklason LE. Pressure-Regulated Ventilator Splitting for Disaster Relief: Design, Testing, and Clinical Experience. Anesthesia & Analgesia 2021, 134: 1094-1105. PMID: 34928890, DOI: 10.1213/ane.0000000000005825.
- Akhtar S. Preoperative evaluation of geriatric patients undergoing liver transplantation. Current Opinion In Anaesthesiology 2021, 35: 96-104. PMID: 34878418, DOI: 10.1097/aco.0000000000001084.
- Akhtar S. Neurological Aging and Pharmacological Management of Geriatric Patients. Current Anesthesiology Reports 2021, 11: 381-386. DOI: 10.1007/s40140-021-00497-8.
- Ammar M, Ammar A, Cheung C, Akhtar S. Pharmacological Adjuncts to Palliation in the Trauma Patient: Optimal Symptom Management. Current Trauma Reports 2021, 7: 73-82. DOI: 10.1007/s40719-021-00215-z.
- Akhtar S, Bardia A, Schonberger RB. Reply to: Comment on: Variation in propofol induction doses administered to surgical patients over 65. Journal Of The American Geriatrics Society 2021, 69: 2680-2681. PMID: 34185888, PMCID: PMC8440365, DOI: 10.1111/jgs.17327.
- Schonberger RB, Bardia A, Dai F, Michel G, Yanez D, Curtis JP, Vaughn MT, Burg MM, Mathis M, Kheterpal S, Akhtar S, Shah N. Variation in propofol induction doses administered to surgical patients over age 65. Journal Of The American Geriatrics Society 2021, 69: 2195-2209. PMID: 33788251, PMCID: PMC8373684, DOI: 10.1111/jgs.17139.
- Lumas S, Hsiang W, Akhtar S, Ochoa Chaar CI. Regional Anesthesia is Underutilized for Carotid Endarterectomy Despite Improved Perioperative Outcomes Compared with General Anesthesia. Annals Of Vascular Surgery 2020, 73: 336-343. PMID: 33373769, DOI: 10.1016/j.avsg.2020.11.035.
- Chen EY, Michel G, Zhou B, Dai F, Akhtar S, Schonberger RB. An Analysis of Anesthesia Induction Dosing in Female Older Adults. Drugs & Aging 2020, 37: 435-446. PMID: 32300966, PMCID: PMC7359723, DOI: 10.1007/s40266-020-00760-3.
- Ammar M, Ammar A, Deshpande R, Band M, Akhtar S. 321: RELATIONSHIP BETWEEN GLUCOSE TIME IN RANGE IN DIABETIC AND NONDIABETIC PATIENTS AND MORTALITY. Critical Care Medicine 2020, 48: 143-143. DOI: 10.1097/01.ccm.0000619640.00502.9a.
- Tao J, Bukanova EN, Akhtar S. Safety of 4-factor prothrombin complex concentrate (4F-PCC) for emergent reversal of factor Xa inhibitors. Journal Of Intensive Care 2018, 6: 34. PMID: 29942519, PMCID: PMC6001072, DOI: 10.1186/s40560-018-0303-y.
- Akhtar S. Perioperative Outcome in Geriatric Patients. Current Anesthesiology Reports 2018, 8: 232-237. DOI: 10.1007/s40140-018-0267-4.
- Akhtar S. Pharmacological considerations in the elderly. Current Opinion In Anaesthesiology 2018, 31: 11-18. PMID: 29189287, DOI: 10.1097/aco.0000000000000544.
- Freudzon L, Akhtar S, London M, Barash P, Badescu G, Sherman B, Zaidan J. Chapter 9 Electrocardiographic Monitoring. 2018, 168-202. DOI: 10.1016/b978-0-323-49798-5.00009-7.
- Tantawy H, Li A, Dai F, Elgammal M, Sukumar N, Elefteriades J, Akhtar S. Association of red blood cell transfusion and short- and longer-term mortality after coronary artery bypass graft surgery. Journal Of Cardiothoracic And Vascular Anesthesia 2017, 32: 1225-1232. PMID: 29402623, DOI: 10.1053/j.jvca.2017.12.033.
- Akhtar S, Ebert T. Cardiovascular System. 2017, 161-178. DOI: 10.1007/978-3-319-66878-9_11.
- Akhtar S. Hemophilia. 2017, 327-332. DOI: 10.1007/978-3-319-50141-3_42.
- Chen EY, Sukumar N, Dai F, Akhtar S, Schonberger RB. A Pilot Analysis of the Association Between Types of Monitored Anesthesia Care Drugs and Outcomes in Transfemoral Aortic Valve Replacement Performed Without General Anesthesia. Journal Of Cardiothoracic And Vascular Anesthesia 2017, 32: 666-671. PMID: 29277298, PMCID: PMC5766429, DOI: 10.1053/j.jvca.2017.07.009.
- Akhtar S, Heng J, Dai F, Schonberger RB, Burg MM. A Retrospective Observational Study of Anesthetic Induction Dosing Practices in Female Elderly Surgical Patients: Are We Overdosing Older Patients? Drugs & Aging 2016, 33: 737-746. PMID: 27581549, DOI: 10.1007/s40266-016-0394-x.
- Akhtar S, Liu J, Heng J, Dai F, Schonberger RB, Burg MM. Does intravenous induction dosing among patients undergoing gastrointestinal surgical procedures follow current recommendations: a study of contemporary practice. Journal Of Clinical Anesthesia 2016, 33: 208-215. PMID: 27555166, DOI: 10.1016/j.jclinane.2016.02.001.
- Akhtar S. Erratum to Case 3—2015 Preventing Adverse Outcomes in the Very Elderly Cardiac Surgical Patients J Cardiothorac Vasc Anesth 29(2015):510-521. Journal Of Cardiothoracic And Vascular Anesthesia 2015, 29: e37. DOI: 10.1053/j.jvca.2015.04.026.
- Akhtar S, Ramani R. Geriatric Pharmacology. Anesthesiology Clinics 2015, 33: 457-469. PMID: 26315631, DOI: 10.1016/j.anclin.2015.05.004.
- Akhtar S, Morris B, Roy R, Balogun SA. Case 3–2015 Preventing Adverse Outcomes in the Very Elderly Cardiac Surgical Patients. Journal Of Cardiothoracic And Vascular Anesthesia 2014, 29: 510-521. PMID: 25440648, DOI: 10.1053/j.jvca.2014.07.014.
- Akhtar S. Kidney Injury After Vascular Surgery. 2014, 125-134. DOI: 10.1007/978-1-4939-1273-5_10.
- Deshpande R, Akhtar S, Haddadin AS. Utility of ultrasound in the ICU. Current Opinion In Anaesthesiology 2014, 27: 123-132. PMID: 24589673, DOI: 10.1097/aco.0000000000000057.
- Akhtar S, Rooke G. Cardiovascular ageing. 2014, 41-52. DOI: 10.1093/med/9780199604999.003.0006.
- Heng J, Akhtar S. Increased Hypotension Due to Age-Uncorrected Anesthetic Dosing in the Elderly: A Single Institutional Study. CHEST Journal 2014, 145: 188a-1-188a-2. DOI: 10.1378/chest.1835524.
- Akhtar S. Guidelines and Perioperative Care of the Elderly. International Anesthesiology Clinics 2014, 52: 64-76. PMID: 25268865, DOI: 10.1097/aia.0000000000000033.
- Akhtar S. Vascular Surgery: Endovascular and Major Vascular Surgery. 2012, 235-253. DOI: 10.1007/978-1-4614-3888-5_16.
- Akhtar S. Chapter 13 Diseases of the Endocrine System. 2012, 401-432. DOI: 10.1016/b978-1-4377-2787-6.00013-9.
- Alexanian SM, McDonnell ME, Akhtar S. Creating a Perioperative Glycemic Control Program. Anesthesiology Research And Practice 2011, 2011: 465974. PMID: 21912542, PMCID: PMC3168770, DOI: 10.1155/2011/465974.
- Maerz LL, Akhtar S. Perioperative glycemic management in 2011. Current Opinion In Critical Care 2011, 17: 370-375. PMID: 21734491, DOI: 10.1097/mcc.0b013e328348beb7.
- Akhtar S, Matei V, London M, Barash P. 15 Electrocardiographic Monitoring. 2011, 452-465. DOI: 10.1016/b978-1-4377-1617-7.00017-0.
- Akhtar S. Diabetic Ketoacidosis (DKA). 2011, 122. DOI: 10.1016/b978-1-4377-1720-4.00109-6.
- Akhtar S, Rappa R, Ghori M. Pain Management in Elderly Patients. 2010, 699-713. DOI: 10.1007/978-0-387-87579-8_32.
- Barash P, Akhtar S. Coronary stents: factors contributing to perioperative major adverse cardiovascular events. British Journal Of Anaesthesia 2010, 105: i3-i15. PMID: 21148653, DOI: 10.1093/bja/aeq318.
- Mirchandani A, Akhtar S. Pain pathways and pain processing. 2010, 7-12. DOI: 10.1017/cbo9780511841378.003.
- Conlin F, Akhtar S. Overview of adrenergic and serotoninergic pain suppression. 2010, 328-329. DOI: 10.1017/cbo9780511841378.080.
- Peterfreund RA, Akhtar S. How Sweet It Is … (or Isn’t)! Anesthesia & Analgesia 2010, 110: 979-981. PMID: 20357141, DOI: 10.1213/ane.0b013e3181d4527e.
- Akhtar S, Barash PG, Inzucchi SE. Scientific Principles and Clinical Implications of Perioperative Glucose Regulation and Control. Anesthesia & Analgesia 2010, 110: 478-497. PMID: 20081134, DOI: 10.1213/ane.0b013e3181c6be63.
- Akhtar S. Fat Embolism. Anesthesiology Clinics 2009, 27: 533-550. PMID: 19825491, DOI: 10.1016/j.anclin.2009.07.018.
- Akhtar S, Podgoreanu M, Harrison B, Brull S. Effect of lidocaine on endothelin-1-mediated airway smooth muscle contraction in the rat trachea. Minerva Anestesiologica 2008, 74: 643-50. PMID: 18971893.
- Akhtar S, Assaad, Amin M, Holt NF, Barash PG, Silverman DG. Preoperative β-blocker use: impact of national guidelines on clinical practice. Journal Of Clinical Anesthesia 2008, 20: 122-128. PMID: 18410867, DOI: 10.1016/j.jclinane.2007.09.012.
- Akhtar S. CHAPTER 1 Ischemic Heart Disease. 2008, 1-25. DOI: 10.1016/b978-1-4160-3998-3.10001-6.
- Tantawy H, Silverman TJ, Silverman DG, Akhtar S. Survey of anesthesiologists as to the value of prior ECG in a patient with nonspecific ST-T wave changes. Connecticut Medicine 2007, 71: 453-6. PMID: 17902381.
- Akhtar S. Pulmonary Physiology Review. 2007, 23-44. DOI: 10.3109/9781420016840-3.
- Akhtar S. Pulmonary Physiology Review. 2007, 868-889. DOI: 10.1201/b16040-46.
- Ranjbaran H, Sokol SI, Gallo A, Eid RE, Iakimov AO, D’Alessio A, Kapoor JR, Akhtar S, Howes CJ, Aslan M, Pfau S, Pober JS, Tellides G. An Inflammatory Pathway of IFN-γ Production in Coronary Atherosclerosis. The Journal Of Immunology 2007, 178: 592-604. PMID: 17182600, DOI: 10.4049/jimmunol.178.1.592.
- Akhtar S. Ischemic Heart Disease. Anesthesiology Clinics 2006, 24: 461-485. PMID: 17240602, DOI: 10.1016/j.atc.2006.04.002.
- Ranjbaran H, Wang Y, Manes TD, Yakimov AO, Akhtar S, Kluger MS, Pober JS, Tellides G. Heparin Displaces Interferon-γ–Inducible Chemokines (IP-10, I-TAC, and Mig) Sequestered in the Vasculature and Inhibits the Transendothelial Migration and Arterial Recruitment of T Cells. Circulation 2006, 114: 1293-1300. PMID: 16940188, DOI: 10.1161/circulationaha.106.631457.
- Martinez EA, Nass CM, Jermyn RM, Rosenbaum SH, Akhtar S, Chan DW, Malkus H, Weiss JL, Fleisher LA. Intermittent Cardiac Troponin-I Screening is an Effective Means of Surveillance for a Perioperative Myocardial Infarction. Journal Of Cardiothoracic And Vascular Anesthesia 2005, 19: 577-582. PMID: 16202889, DOI: 10.1053/j.jvca.2005.07.002.
- Akhtar S, Amin M, Tantawy H, Senior A, Barash PG, Silverman DG. Preoperative β-blocker use: is titration to a heart rate of 60 beats per minute a consistently attainable goal? Journal Of Clinical Anesthesia 2005, 17: 191-197. PMID: 15896586, DOI: 10.1016/j.jclinane.2004.06.020.
- Silverman D, Akhtar S. DES, Not Always the Best! Critical Care Medicine 2004, 32: 2166. DOI: 10.1097/01.ccm.0000139632.93986.0d.
- Akhtar S, Silverman DG. Assessment and management of patients with ischemic heart disease. Critical Care Medicine 2004, 32: s126-s136. PMID: 15064671, DOI: 10.1097/01.ccm.0000121576.73871.2d.
- Akhtar S. Biomarkers and perioperative myocardial infarction. Journal Of Critical Care 2003, 22: 50-61. DOI: 10.1016/s0277-0326(02)00002-8.
- Akhtar S, Silverman D, Senior A, Manning C, Barash P. Pre-Operative Beta-Blocker Use in High Risk Patients: Is There Room for Improvement? Anesthesiology 2002, 96: a224. DOI: 10.1097/00000542-200209002-00224.
- Akhtar S, Barash PG. Significance of beta‐blockers in the perioperative period. Current Opinion In Anaesthesiology 2002, 15: 27. PMID: 17019181, DOI: 10.1097/00001503-200202000-00005.
- Akhtar S, Barash PG. Perioperative Use of Beta-Blockers: Past, Present, and Future. International Anesthesiology Clinics 2002, 40: 133-157. PMID: 11897941, DOI: 10.1097/00004311-200204000-00012.
- Akhtar S, Podgoreanu M. PDGF-Induced DNA Synthesis in Human Lung Fibroblast is Inhibited by Lidocaine. Anesthesiology 2001, 2001: b25. DOI: 10.1097/00000542-200109001-00025.
- Akhtar S, Fleisher L, Jermyn R, Chan D, Rosenbaum S. Room 302, 10/18/2000 9: 00 AM - 10: 30 AM (PD) Detection of Perioperative Ischemia is Improved by Troponin (TnI) Measurement. Anesthesiology 2000, 93: a-253. DOI: 10.1097/00000542-200009001-00253.
- Akhtar S, Fleisher L, Jermyn R, Weiss J, Rosenbaum S. Room 302, 10/18/2000 9: 00 AM - 10: 30 AM (PD) Incidence of Perioperative Myocardial Injury Based on ACC/ AHA Guidelines in Vascular Surgery Patients. Anesthesiology 2000, 93: a-260. DOI: 10.1097/00000542-200009001-00260.
- Akhtar S, EghbaliWebb M. Room A, 10/16/2000 9: 00 AM - 11: 00 AM (PS) Effect of Lidocaine on DNA Synthesis in Human Lung Fibroblasts. Anesthesiology 2000, 93: a-813. DOI: 10.1097/00000542-200009001-00813.
- Akhtar S, Weigle C, Cheng E, Toohill R, Berens R. Use of active noise cancellation devices in caregivers in the intensive care unit. Critical Care Medicine 2000, 28: 1157-1160. PMID: 10809298, DOI: 10.1097/00003246-200004000-00040.
- Akhtar S. Con: Preoperative thallium testing should not be performed routinely before vascular surgery. Journal Of Cardiothoracic And Vascular Anesthesia 2000, 14: 221-223. PMID: 10794348, DOI: 10.1016/s1053-0770(00)90024-7.
- RABY K, BRULL S, TIMIMI F, AKHTAR S, ROSENBAUM S, NAIMI C, WHITTEMORE A. The Effect of Heart Rate Control on Myocardial Ischemia Among High-Risk Patients After Vascular Surgery. Survey Of Anesthesiology 2000, 44: 10. DOI: 10.1097/00132586-200002000-00010.
- Akhtar S, Brull S. INTRAOPERATIVE USE OF ANTICOAGULANTS AND ANTITHROMBOTICS Heparin and Beyond. Anesthesiology Clinics 1999, 17: 831-860. DOI: 10.1016/s0889-8537(05)70136-x.
- Akhtar S, Mazzeo A, Cheng E, Bosnjak Z, Kampine J. Differential bronchodilatory effects of terbutaline, diltiazem, and aminophylline in canine intraparenchymal airways. Critical Care Medicine 1999, 27: 1551-1556.. PMID: 10470763, DOI: 10.1097/00003246-199908000-00024.
- Raby K, Brull S, Timimi F, Akhtar S, Rosenbaum S, Naimi C, Whittemore A. The effect of heart rate control on myocardial ischemia among high-risk patients after vascular surgery. Anesthesia & Analgesia 1999, 88: 477-82. PMID: 10071990, DOI: 10.1097/00000539-199903000-00002.
- Raby K, Brull S, Timimi F, Akhtar S, Rosenbaum S, Naimi C, Whittemore A. The Effect of Heart Rate Control on Myocardial Ischemia Among High-Risk Patients After Vascular Surgery. Anesthesia & Analgesia 1999, 88: 477-482.. DOI: 10.1213/00000539-199903000-00002.
- Akhtar S, Silverman D, Brull S. EFFECTS OF LIDOCAINE ON ENDOTHELIN-1 INDUCED CONSTRICTION IN RAT TRACHEA. Anesthesia & Analgesia 1998, 86: 424s.. DOI: 10.1097/00000539-199802001-00422.
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