Emmanuelle Schindler, MD, PhD
Neurology
Titles
- Assistant Professor
- Medical Director, Headache Center of Excellence
Education & Training
- Advanced Research FellowVA Connecticut Healthcare System (2018)
- ResidentYale School of Medicine (2016)
- MDDrexel University College of Medicine (2012)
- PhDDrexel University College of Medicine, Neuroscience (2010)
- BSCollege of William & Mary, Biological Psychiatry (2003)
Languages Spoken
- English
- Français (French)
Additional Information
Honors & Recognitions
- Kindness Award: VA Connecticut Healthcare System (2019)
- Gilbert Glaser Award: Yale Neurology (2015)
- American Academy of Neurology Award: American Academy of Neurology (2012)
Board Certifications
- AB of Psychiatry & Neurology, Neurology
- United Council for Neurologic Subspecialties, Headache Medicine
Professional Service
- International Society for Research on Psychedelics (2019 - Present): Member
- International Headache Society (2017 - Present): Member
- American Headache Society (2014 - Present): Member
- American Academy of Neurology (2003 - Present): Member
Publications
- Schindler EAD, Burish MJ. Recent advances in the diagnosis and management of cluster headache. BMJ (Clinical Research Ed.) 2022, 376: e059577. PMID: 35296510, DOI: 10.1136/bmj-2020-059577.
- Grinberg AS, Best RD, Min KM, Schindler EAD, Koo BB, Sico JJ, Seng EK. Cluster Headache: Clinical Characteristics and Opportunities to Enhance Quality of Life. Current Pain And Headache Reports 2021, 25: 65. PMID: 34668084, DOI: 10.1007/s11916-021-00979-8.
- Koo BB, Bayoumi A, Albanna A, Abusuliman M, Burrone L, Sico JJ, Schindler EAD. Demoralization predicts suicidality in patients with cluster headache. The Journal Of Headache And Pain 2021, 22: 28. PMID: 33879041, PMCID: PMC8056539, DOI: 10.1186/s10194-021-01241-7.
- Schindler EAD, Cooper V, Quine DB, Fenton BT, Wright DA, Weil MJ, Sico JJ. "You will eat shoe polish if you think it would help"-Familiar and lesser-known themes identified from mixed-methods analysis of a cluster headache survey. Headache 2021, 61: 318-328. PMID: 33502769, DOI: 10.1111/head.14063.
- Schindler EAD, Sewell RA, Gottschalk CH, Luddy C, Flynn LT, Lindsey H, Pittman BP, Cozzi NV, D'Souza DC. Exploratory Controlled Study of the Migraine-Suppressing Effects of Psilocybin. Neurotherapeutics : The Journal Of The American Society For Experimental NeuroTherapeutics 2021, 18: 534-543. PMID: 33184743, PMCID: PMC8116458, DOI: 10.1007/s13311-020-00962-y.
- Schindler EAD, Schnakenberg Martin AM, Sewell RA, Ranganathan M, DeForest A, Pittman BP, Perrino A, D'Souza DC. In an exploratory randomized, double-blind, placebo-controlled, cross-over study, psychoactive doses of intravenous delta-9-tetrahydrocannabinol fail to produce antinociceptive effects in healthy human volunteers. Psychopharmacology 2020, 237: 3097-3107. PMID: 32632491, DOI: 10.1007/s00213-020-05595-9.
- Schindler EAD. Pharmacological, physiological, and familial factors in propranolol-induced visions. Neurology. Clinical Practice 2020, 10: e25-e26. PMID: 32612878, PMCID: PMC7292560, DOI: 10.1212/CPJ.0000000000000698.
- Schindler EAD, Wright DA, Weil MJ, Gottschalk CH, Pittman BP, Sico JJ. Survey Analysis of the Use, Effectiveness, and Patient-Reported Tolerability of Inhaled Oxygen Compared With Injectable Sumatriptan for the Acute Treatment of Cluster Headache. Headache 2018, 58: 1568-1578. PMID: 30221765, DOI: 10.1111/head.13405.
- Schindler EAD, Wallace RM, Sloshower JA, D'Souza DC. Neuroendocrine Associations Underlying the Persistent Therapeutic Effects of Classic Serotonergic Psychedelics. Frontiers In Pharmacology 2018, 9: 177. PMID: 29545753, PMCID: PMC5838010, DOI: 10.3389/fphar.2018.00177.
- Schindler EA, Guo XM, Schrag M, Ghoshal S, Schilsky ML, Beslow LA. Neuropsychiatric Presentation of Wilson Disease in an Adolescent Male. Neuropediatrics 2016, 47: 346-7. PMID: 27490186, DOI: 10.1055/s-0036-1586225.
- Schindler EA, Gottschalk CH, Weil MJ, Shapiro RE, Wright DA, Sewell RA. Indoleamine Hallucinogens in Cluster Headache: Results of the Clusterbusters Medication Use Survey. Journal Of Psychoactive Drugs 2015, 47: 372-81. PMID: 26595349, DOI: 10.1080/02791072.2015.1107664.
- Schindler EA, Tirado-Morales DJ, Kushon D. Clonidine abuse in a methadone-maintained, clonazepam-abusing patient. Journal Of Addiction Medicine 2013, 7: 218-9. PMID: 23519051, DOI: 10.1097/ADM.0b013e31828ab8d4.
- Schindler EA, Harvey JA, Aloyo VJ. Phospholipase C mediates (±)-1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane (DOI)-, but not lysergic acid diethylamide (LSD)-elicited head bobs in rabbit medial prefrontal cortex. Brain Research 2013, 1491: 98-108. PMID: 23123701, PMCID: PMC3559188, DOI: 10.1016/j.brainres.2012.10.057.
- Schindler EA, Dave KD, Smolock EM, Aloyo VJ, Harvey JA. Serotonergic and dopaminergic distinctions in the behavioral pharmacology of (±)-1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane (DOI) and lysergic acid diethylamide (LSD). Pharmacology, Biochemistry, And Behavior 2012, 101: 69-76. PMID: 22197710, PMCID: PMC3272148, DOI: 10.1016/j.pbb.2011.12.002.
- Romano AG, Quinn JL, Li L, Dave KD, Schindler EA, Aloyo VJ, Harvey JA. Intrahippocampal LSD accelerates learning and desensitizes the 5-HT(2A) receptor in the rabbit, Romano et al. Psychopharmacology 2010, 212: 441-8. PMID: 20827462, DOI: 10.1007/s00213-010-2004-7.
Departments and Programs
Titles
- Assistant Professor
- Medical Director, Headache Center of Excellence
Education & Training
- Advanced Research FellowVA Connecticut Healthcare System (2018)
- ResidentYale School of Medicine (2016)
- MDDrexel University College of Medicine (2012)
- PhDDrexel University College of Medicine, Neuroscience (2010)
- BSCollege of William & Mary, Biological Psychiatry (2003)
Languages Spoken
- English
- Français (French)
Additional Information
Honors & Recognitions
- Kindness Award: VA Connecticut Healthcare System (2019)
- Gilbert Glaser Award: Yale Neurology (2015)
- American Academy of Neurology Award: American Academy of Neurology (2012)
Board Certifications
- AB of Psychiatry & Neurology, Neurology
- United Council for Neurologic Subspecialties, Headache Medicine
Professional Service
- International Society for Research on Psychedelics (2019 - Present): Member
- International Headache Society (2017 - Present): Member
- American Headache Society (2014 - Present): Member
- American Academy of Neurology (2003 - Present): Member
Publications
- Schindler EAD, Burish MJ. Recent advances in the diagnosis and management of cluster headache. BMJ (Clinical Research Ed.) 2022, 376: e059577. PMID: 35296510, DOI: 10.1136/bmj-2020-059577.
- Grinberg AS, Best RD, Min KM, Schindler EAD, Koo BB, Sico JJ, Seng EK. Cluster Headache: Clinical Characteristics and Opportunities to Enhance Quality of Life. Current Pain And Headache Reports 2021, 25: 65. PMID: 34668084, DOI: 10.1007/s11916-021-00979-8.
- Koo BB, Bayoumi A, Albanna A, Abusuliman M, Burrone L, Sico JJ, Schindler EAD. Demoralization predicts suicidality in patients with cluster headache. The Journal Of Headache And Pain 2021, 22: 28. PMID: 33879041, PMCID: PMC8056539, DOI: 10.1186/s10194-021-01241-7.
- Schindler EAD, Cooper V, Quine DB, Fenton BT, Wright DA, Weil MJ, Sico JJ. "You will eat shoe polish if you think it would help"-Familiar and lesser-known themes identified from mixed-methods analysis of a cluster headache survey. Headache 2021, 61: 318-328. PMID: 33502769, DOI: 10.1111/head.14063.
- Schindler EAD, Sewell RA, Gottschalk CH, Luddy C, Flynn LT, Lindsey H, Pittman BP, Cozzi NV, D'Souza DC. Exploratory Controlled Study of the Migraine-Suppressing Effects of Psilocybin. Neurotherapeutics : The Journal Of The American Society For Experimental NeuroTherapeutics 2021, 18: 534-543. PMID: 33184743, PMCID: PMC8116458, DOI: 10.1007/s13311-020-00962-y.
- Schindler EAD, Schnakenberg Martin AM, Sewell RA, Ranganathan M, DeForest A, Pittman BP, Perrino A, D'Souza DC. In an exploratory randomized, double-blind, placebo-controlled, cross-over study, psychoactive doses of intravenous delta-9-tetrahydrocannabinol fail to produce antinociceptive effects in healthy human volunteers. Psychopharmacology 2020, 237: 3097-3107. PMID: 32632491, DOI: 10.1007/s00213-020-05595-9.
- Schindler EAD. Pharmacological, physiological, and familial factors in propranolol-induced visions. Neurology. Clinical Practice 2020, 10: e25-e26. PMID: 32612878, PMCID: PMC7292560, DOI: 10.1212/CPJ.0000000000000698.
- Schindler EAD, Wright DA, Weil MJ, Gottschalk CH, Pittman BP, Sico JJ. Survey Analysis of the Use, Effectiveness, and Patient-Reported Tolerability of Inhaled Oxygen Compared With Injectable Sumatriptan for the Acute Treatment of Cluster Headache. Headache 2018, 58: 1568-1578. PMID: 30221765, DOI: 10.1111/head.13405.
- Schindler EAD, Wallace RM, Sloshower JA, D'Souza DC. Neuroendocrine Associations Underlying the Persistent Therapeutic Effects of Classic Serotonergic Psychedelics. Frontiers In Pharmacology 2018, 9: 177. PMID: 29545753, PMCID: PMC5838010, DOI: 10.3389/fphar.2018.00177.
- Schindler EA, Guo XM, Schrag M, Ghoshal S, Schilsky ML, Beslow LA. Neuropsychiatric Presentation of Wilson Disease in an Adolescent Male. Neuropediatrics 2016, 47: 346-7. PMID: 27490186, DOI: 10.1055/s-0036-1586225.
- Schindler EA, Gottschalk CH, Weil MJ, Shapiro RE, Wright DA, Sewell RA. Indoleamine Hallucinogens in Cluster Headache: Results of the Clusterbusters Medication Use Survey. Journal Of Psychoactive Drugs 2015, 47: 372-81. PMID: 26595349, DOI: 10.1080/02791072.2015.1107664.
- Schindler EA, Tirado-Morales DJ, Kushon D. Clonidine abuse in a methadone-maintained, clonazepam-abusing patient. Journal Of Addiction Medicine 2013, 7: 218-9. PMID: 23519051, DOI: 10.1097/ADM.0b013e31828ab8d4.
- Schindler EA, Harvey JA, Aloyo VJ. Phospholipase C mediates (±)-1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane (DOI)-, but not lysergic acid diethylamide (LSD)-elicited head bobs in rabbit medial prefrontal cortex. Brain Research 2013, 1491: 98-108. PMID: 23123701, PMCID: PMC3559188, DOI: 10.1016/j.brainres.2012.10.057.
- Schindler EA, Dave KD, Smolock EM, Aloyo VJ, Harvey JA. Serotonergic and dopaminergic distinctions in the behavioral pharmacology of (±)-1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane (DOI) and lysergic acid diethylamide (LSD). Pharmacology, Biochemistry, And Behavior 2012, 101: 69-76. PMID: 22197710, PMCID: PMC3272148, DOI: 10.1016/j.pbb.2011.12.002.
- Romano AG, Quinn JL, Li L, Dave KD, Schindler EA, Aloyo VJ, Harvey JA. Intrahippocampal LSD accelerates learning and desensitizes the 5-HT(2A) receptor in the rabbit, Romano et al. Psychopharmacology 2010, 212: 441-8. PMID: 20827462, DOI: 10.1007/s00213-010-2004-7.
Departments and Programs