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Phase III

STaR Trial: Multiple Ligament Knee Injuries

  • Study HIC#:2000030264
  • Last Updated:04/30/2023

The purpose of this research is to address two questions regarding a multiple ligament knee injury (MLKI). 

  • Is it best to have surgery shortly after injury or to delay surgery for MLKI? 
  • Is it best to begin weight bearing and range of motion shortly after surgery or delay it for a few weeks?  

The study will randomize eligible patients to determine whether they have early or delayed surgery as well as early or delayed rehabilitation. The type of surgery and rehabilitation is based on the injury itself. The study team will meet with the patient at their regularly scheduled office appointments, review medical records and ask that they fill out questionnaires electronically for 2 years after surgery.   

  • Age16 years - 55 years
  • GenderBoth

Contact Us

For more information about this study, including how to volunteer, contact:

Catherine Tsao

Help Us Discover!

You can help our team find trials you might be eligible for by creating a volunteer profile in MyChart. To get started, create a volunteer profile, or contact helpusdiscover@yale.edu, or call +18779788343 for more information.

Trial Purpose and Description

The purpose of this research is to address two questions regarding a multiple ligament knee injury (MLKI). 

  • Is it best to have surgery shortly after injury or to delay surgery for MLKI? 
  • Is it best to begin weight bearing and range of motion shortly after surgery or delay it for a few weeks?  

The study will randomize eligible patients to determine whether they have early or delayed surgery as well as early or delayed rehabilitation. The type of surgery and rehabilitation is based on the injury itself. The study team will meet with the patient at their regularly scheduled office appointments, review medical records and ask that they fill out questionnaires electronically for 2 years after surgery.   

Eligibility Criteria

Ages 16 - 55 years and the study participant must have obtained an injury to their knee which involves more than one ligament. 

Principal Investigator

Sub-Investigator

For more information about this study, including how to volunteer, contact: