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Restless Legs Syndrome: The Role of Melanocortin Hormones

  • Study HIC#:2000026723
  • Last Updated:01/01/0001

Researchers at Yale University are conducting research to determine whether specific stress hormone levels are increased in the blood and cerebrospinal fluid of persons with RLS. This study requires a one-time visit to New Haven, Connecticut, you will be reimbursed for the COST OF YOUR TRAVEL (up to $600). Your first contact can be via email to abdalla.albanna@yale.edu at or call (203) 785-7393.

  • Age18 years and older
  • GenderBoth

Contact Us

For more information about this study, including how to volunteer, contact:

Mohamed Kandil

Help Us Discover!

You can help our team find trials you might be eligible for by creating a volunteer profile in MyChart. To get started, create a volunteer profile, or contact helpusdiscover@yale.edu, or call +18779788343 for more information.

Trial Purpose and Description

The purpose of our study is to determine whether levels of melanocortin (MC) hormones are elevated in the serum and cerebrospinal fluid (CSF) of persons with restless legs syndrome (RLS) compared to controls without RLS. 

The secondary purpose of this study is to determine whether levels of MC hormones correlate to the severity of RLS symptoms, sleep disruption, frequency of periodic limb movements during sleep (PLMS), depression/suicidality, and/or pain sensitivity.

Eligibility Criteria

  1. Eligibility criteria: Above 18 years of age, with primary Restless Legs Syndrome or healthy volunteers, eligibility will be determined by research staff on the phone.

Principal Investigator

For more information about this study, including how to volunteer, contact: