Regional Versus General Anesthesia for Promoting Independence After Hip Fracture (REGAIN)
- Study HIC#:1605017791
- Last Updated:07/12/2021
The purpose of this study is to find out if two types of standard care anesthesia are the same or if one is better for people who have hip fractures.
- Age50 years and older
- Start Date03/02/2017
- End Date12/31/2021
Trial Purpose and Description
The purpose of this active comparator study is to evaluate the effect of two different standard care anesthesia care approaches for hip fracture surgery, on recovery of ambulation at approximately 60 days (primary outcome) and other patient-centered outcomes measured at 365 days (±60 days). The two approaches are spinal anesthesia (spinal block) and general anesthesia. Our overarching hypothesis is that patients undergoing hip fracture surgery with spinal anesthesia will demonstrate improved ambulation at approximately 60 days and better outcomes across a range of patient-centered endpoints compared to patients receiving general anesthesia.
Clinically or radiographically diagnosed intracapsular or extracapsular hip fracture
Planned surgical treatment via hemiarthroplasty, total hip arthroplasty or appropriate fixation procedure
Ability to walk 10 feet or across a room without human assistance before fracture
Planned concurrent surgery not amenable to spinal anesthesia
Absolute contraindications to spinal anesthesia