Immune Response Analysis in Lymph Node Tissue
- Study HIC#:2000032631
- Last Updated:05/24/2024
Planning to update your COVID vaccine?
Yale researchers are studying the immune response to COVID vaccinations among healthy and immune suppressed individuals. If you are planning to update your vaccine, you may qualify for a research study.
Qualifying participants should be:
- Age 18 or older
- Planning to update their COVID19 vaccination within the next 90 days
- EITHER:
- Healthy (no history of immune problems and not taking any immune suppressing medicine)
- Taking a B-cell depleting medicine (e.g. rituximab, ocrelizumab, ofatumumab) to treat an autoimmune disease
- Taking glatiramer or interferon-type medication to treat an autoimmune disease
Participants in this research project will have a fine needle aspiration and/or biopsy of lymph nodes in their armpit before and at several timepoints after vaccination. Ultrasounds will be performed before these procedures to visualize the lymph nodes. Blood will also be collected. There would be 4-6 study visits over about 10 weeks. Compensation of up to $1000 is available.
If you are interested, please complete the pre-screening survey at https://redcap.link/9md3047j or email MSResearch@yale.edu.
Contact Us
For more information about this study, including how to volunteer, contact:
MS Research
Help Us Discover!
You can help our team find trials you might be eligible for by creating a volunteer profile in MyChart. To get started, create a volunteer profile, or contact helpusdiscover@yale.edu, or call +18779788343 for more information.
Trial Purpose and Description
Planning to update your COVID vaccine?
Yale researchers are studying the immune response to COVID vaccinations among healthy and immune suppressed individuals. If you are planning to update your vaccine, you may qualify for a research study.
Qualifying participants should be:
- Age 18 or older
- Planning to update their COVID19 vaccination within the next 90 days
- EITHER:
- Healthy (no history of immune problems and not taking any immune suppressing medicine)
- Taking a B-cell depleting medicine (e.g. rituximab, ocrelizumab, ofatumumab) to treat an autoimmune disease
- Taking glatiramer or interferon-type medication to treat an autoimmune disease
Participants in this research project will have a fine needle aspiration and/or biopsy of lymph nodes in their armpit before and at several timepoints after vaccination. Ultrasounds will be performed before these procedures to visualize the lymph nodes. Blood will also be collected. There would be 4-6 study visits over about 10 weeks. Compensation of up to $1000 is available.
If you are interested, please complete the pre-screening survey at https://redcap.link/9md3047j or email MSResearch@yale.edu.
Eligibility Criteria
Qualifying participants should be:
- Age 18 or older
- Planning to update their COVID19 vaccination within the next 90 days
- EITHER:
- Healthy (no history of immune problems and not taking any immune suppressing medicine)
- Taking a B-cell depleting medicine (e.g. rituximab, ocrelizumab, ofatumumab) to treat an autoimmune disease
- Taking glatiramer or interferon-type medication to treat an autoimmune disease
