Beckwith-Wiedemann Syndrome
Definition
Beckwith-Wiedemann syndrome (BWS) is a rare genetic disorder characterized by overgrowth of various parts of the body, an increased risk of childhood cancer, and congenital malformations. It is caused by changes in the regulation of genes on chromosome 11. Common features include macrosomia, macroglossia, abdominal wall defects, and neonatal hypoglycemia.